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The map label for this gene is kamA [H]

Identifier: 78358081

GI number: 78358081

Start: 3032194

End: 3033777

Strand: Direct

Name: kamA [H]

Synonym: Dde_3041

Alternate gene names: 78358081

Gene position: 3032194-3033777 (Clockwise)

Preceding gene: 78358080

Following gene: 78358082

Centisome position: 81.29

GC content: 61.81

Gene sequence:

>1584_bases
GTGATTCCGGCCTGTCACAAGGCCGGAACGCAACTGCCCGCCTGTTTTTCGCATTGCGCGCCTGCGCAACCGGAACATCA
TGTTCCGCCCATGCTACAGCCACAGGCAACCTTACTCCATGATATCAGCACGATAAGCAACACATGCCATAATGGCATGG
CAGTTGCTATCCGCGGCTCATTGCGCACGCTGTGCACACGGCAGCGCGCGGTAACCACTACAAGCAGAATCATGGAGAAA
ACGGTGACACTCAGCACTGCAGAACTTGAACAGGCACCCGCAGAGCCTCCTTCTCTAACGACGGCACTTTCCCGCGGCAC
GGCACAGGCTCCCTCGGCCCATGATGCCGCGTCTTTTTCCCGTACCCAGAACACCGCGTCCGGCTTTGTGCTGAGCGCCC
GTTCCGATGCCTTCCGCAGGCGTTTTTACCCCGAAGTCAGCCAGAAGACATGGTCTGACTGGCACTGGCAGTACGCCAAC
CGCATCACCTCGCTCGGCGTGCTGGGCACCATGCTTGGGCTTTCCGAAGAAGAAGCCGGTGCCGGCACGGGGCTTGCCGC
GCTGCCGCTGGCAGTCACCCCTTATTATGCGGCCCAGTTTGACCCGCACAATCCCGCACATCCCCTGCGGCGCACCATGG
TGCCCACAGTGGAGGAATGGTCGCTGAACCCCGGCGAGTCCGCAGACCCGCTGGGTGAAGACAGCCACAGCCCGGTGCCC
GGTCTTGTGCACAGATATCCTGACCGTGTGCTCTTTCTTGCCACGGATTCCTGCTCGGCCTACTGCCGTTACTGCACCCG
CTCGCGCCGCGTGGGCAAGCCCTGCGCCGGCAGTGCCTCGCGCAGACGCTGGCCCGCAGCCATCGAATACATAGAAAATC
ACCCCGAAGTGCGCGATGTGCTCATCTCCGGCGGCGACCCGCTGACCATGACGGACAGTGCACTCAACCACCTGCTGTCA
CAGTTGCGCCGTATTCCGCATGTGGAATTCATCCGCATAGGAACCAAGGCGCCCATCGTCATGCCGCAGCGCATCACGCC
TGCGCTTGTCCGCATGCTGCGCCGGTATCACCCGCTGTTCATGAGCATCCACTGCACGCACCCCGACGAACTGACGCCGG
AAGCGTCTCAGGCGCTCAACCGGCTGGCCGATGGCGGTATTCCGCTGGGCAGCCAGACAGTGCTGCTCAAGGGCATAAAC
GATAACGTGCCCACCATGACAGCTCTTATGCAGGGTCTGCTCAAAAACCGCGTGCGCCCGTACTACCTGTATCATTGCGA
TCCGGTACAGGGTTCGGCGCATTTCCGCACGCCCATATACAAAGGCGTGGAGATAATCCGCGGCATGCGCGGCTTTACCA
CCGGCTATGCCGTGCCCACCTATGTGGTGGACGCTCCCGGCGGGGGCGGCAAAATTCCGCTGATGCCCGATTATGTTCAG
GGATACGACGGCGAAGAGCTTGTCATGCGCAACTATGAAGGCGGCCTGTACCGCTCGTATGACCCCGCGGTGCCCCTTGC
CGCACACAACGTGCACAACGCCGGCCCCGCAGGCTGCGCAGACGGAGACATGCCGTGCTTGTAG

Upstream 100 bases:

>100_bases
CTGCTCACCCGCTACGGCATCGACAAATCCGTGTACAAGCAGTCCAAAAGCGGAACTTCAGGTACCCAAAAATAAAAAAC
GGAACCGGACGTTCCGTTCT

Downstream 100 bases:

>100_bases
GCATTACATACGACCTGAAAGAAGAGTATCTCGCACGGGGCTATTCGGAAGAAGAAGCAGCTGAGTTCGACAGCCCCGCC
ACCATTGAGGGCATAGAAAC

Product: L-lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MIPACHKAGTQLPACFSHCAPAQPEHHVPPMLQPQATLLHDISTISNTCHNGMAVAIRGSLRTLCTRQRAVTTTSRIMEK
TVTLSTAELEQAPAEPPSLTTALSRGTAQAPSAHDAASFSRTQNTASGFVLSARSDAFRRRFYPEVSQKTWSDWHWQYAN
RITSLGVLGTMLGLSEEEAGAGTGLAALPLAVTPYYAAQFDPHNPAHPLRRTMVPTVEEWSLNPGESADPLGEDSHSPVP
GLVHRYPDRVLFLATDSCSAYCRYCTRSRRVGKPCAGSASRRRWPAAIEYIENHPEVRDVLISGGDPLTMTDSALNHLLS
QLRRIPHVEFIRIGTKAPIVMPQRITPALVRMLRRYHPLFMSIHCTHPDELTPEASQALNRLADGGIPLGSQTVLLKGIN
DNVPTMTALMQGLLKNRVRPYYLYHCDPVQGSAHFRTPIYKGVEIIRGMRGFTTGYAVPTYVVDAPGGGGKIPLMPDYVQ
GYDGEELVMRNYEGGLYRSYDPAVPLAAHNVHNAGPAGCADGDMPCL

Sequences:

>Translated_527_residues
MIPACHKAGTQLPACFSHCAPAQPEHHVPPMLQPQATLLHDISTISNTCHNGMAVAIRGSLRTLCTRQRAVTTTSRIMEK
TVTLSTAELEQAPAEPPSLTTALSRGTAQAPSAHDAASFSRTQNTASGFVLSARSDAFRRRFYPEVSQKTWSDWHWQYAN
RITSLGVLGTMLGLSEEEAGAGTGLAALPLAVTPYYAAQFDPHNPAHPLRRTMVPTVEEWSLNPGESADPLGEDSHSPVP
GLVHRYPDRVLFLATDSCSAYCRYCTRSRRVGKPCAGSASRRRWPAAIEYIENHPEVRDVLISGGDPLTMTDSALNHLLS
QLRRIPHVEFIRIGTKAPIVMPQRITPALVRMLRRYHPLFMSIHCTHPDELTPEASQALNRLADGGIPLGSQTVLLKGIN
DNVPTMTALMQGLLKNRVRPYYLYHCDPVQGSAHFRTPIYKGVEIIRGMRGFTTGYAVPTYVVDAPGGGGKIPLMPDYVQ
GYDGEELVMRNYEGGLYRSYDPAVPLAAHNVHNAGPAGCADGDMPCL
>Mature_527_residues
MIPACHKAGTQLPACFSHCAPAQPEHHVPPMLQPQATLLHDISTISNTCHNGMAVAIRGSLRTLCTRQRAVTTTSRIMEK
TVTLSTAELEQAPAEPPSLTTALSRGTAQAPSAHDAASFSRTQNTASGFVLSARSDAFRRRFYPEVSQKTWSDWHWQYAN
RITSLGVLGTMLGLSEEEAGAGTGLAALPLAVTPYYAAQFDPHNPAHPLRRTMVPTVEEWSLNPGESADPLGEDSHSPVP
GLVHRYPDRVLFLATDSCSAYCRYCTRSRRVGKPCAGSASRRRWPAAIEYIENHPEVRDVLISGGDPLTMTDSALNHLLS
QLRRIPHVEFIRIGTKAPIVMPQRITPALVRMLRRYHPLFMSIHCTHPDELTPEASQALNRLADGGIPLGSQTVLLKGIN
DNVPTMTALMQGLLKNRVRPYYLYHCDPVQGSAHFRTPIYKGVEIIRGMRGFTTGYAVPTYVVDAPGGGGKIPLMPDYVQ
GYDGEELVMRNYEGGLYRSYDPAVPLAAHNVHNAGPAGCADGDMPCL

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=326, Percent_Identity=37.1165644171779, Blast_Score=212, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 57539; Mature: 57539

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPACHKAGTQLPACFSHCAPAQPEHHVPPMLQPQATLLHDISTISNTCHNGMAVAIRGS
CCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECH
LRTLCTRQRAVTTTSRIMEKTVTLSTAELEQAPAEPPSLTTALSRGTAQAPSAHDAASFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHH
RTQNTASGFVLSARSDAFRRRFYPEVSQKTWSDWHWQYANRITSLGVLGTMLGLSEEEAG
HHCCCCCCEEEECCHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AGTGLAALPLAVTPYYAAQFDPHNPAHPLRRTMVPTVEEWSLNPGESADPLGEDSHSPVP
CCCCHHHHHHHCCCHHHCCCCCCCCCHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCC
GLVHRYPDRVLFLATDSCSAYCRYCTRSRRVGKPCAGSASRRRWPAAIEYIENHPEVRDV
HHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHE
LISGGDPLTMTDSALNHLLSQLRRIPHVEFIRIGTKAPIVMPQRITPALVRMLRRYHPLF
EECCCCCCEECHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCHHHHHHHHHCCCEE
MSIHCTHPDELTPEASQALNRLADGGIPLGSQTVLLKGINDNVPTMTALMQGLLKNRVRP
EEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCC
YYLYHCDPVQGSAHFRTPIYKGVEIIRGMRGFTTGYAVPTYVVDAPGGGGKIPLMPDYVQ
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCHHHC
GYDGEELVMRNYEGGLYRSYDPAVPLAAHNVHNAGPAGCADGDMPCL
CCCCCHHHEECCCCCCEECCCCCCCEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIPACHKAGTQLPACFSHCAPAQPEHHVPPMLQPQATLLHDISTISNTCHNGMAVAIRGS
CCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECH
LRTLCTRQRAVTTTSRIMEKTVTLSTAELEQAPAEPPSLTTALSRGTAQAPSAHDAASFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHH
RTQNTASGFVLSARSDAFRRRFYPEVSQKTWSDWHWQYANRITSLGVLGTMLGLSEEEAG
HHCCCCCCEEEECCHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AGTGLAALPLAVTPYYAAQFDPHNPAHPLRRTMVPTVEEWSLNPGESADPLGEDSHSPVP
CCCCHHHHHHHCCCHHHCCCCCCCCCHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCC
GLVHRYPDRVLFLATDSCSAYCRYCTRSRRVGKPCAGSASRRRWPAAIEYIENHPEVRDV
HHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHE
LISGGDPLTMTDSALNHLLSQLRRIPHVEFIRIGTKAPIVMPQRITPALVRMLRRYHPLF
EECCCCCCEECHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCHHHHHHHHHCCCEE
MSIHCTHPDELTPEASQALNRLADGGIPLGSQTVLLKGINDNVPTMTALMQGLLKNRVRP
EEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCC
YYLYHCDPVQGSAHFRTPIYKGVEIIRGMRGFTTGYAVPTYVVDAPGGGGKIPLMPDYVQ
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCHHHC
GYDGEELVMRNYEGGLYRSYDPAVPLAAHNVHNAGPAGCADGDMPCL
CCCCCHHHEECCCCCCEECCCCCCCEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]