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The map label for this gene is yciR [C]

Identifier: 78358062

GI number: 78358062

Start: 3008730

End: 3010430

Strand: Direct

Name: yciR [C]

Synonym: Dde_3022

Alternate gene names: 78358062

Gene position: 3008730-3010430 (Clockwise)

Preceding gene: 78358061

Following gene: 78358066

Centisome position: 80.66

GC content: 56.85

Gene sequence:

>1701_bases
GTGACAACAGCCGGTGAACTCTGTATAGTGCGGCAAAACAGGATAGCTGCCACCCCGCTCATGAACTCATTACAACACTT
TCTTCTTACCCCGTTCTCGGCATCTGTAGGCTGCGGCCTGCTGCTGCTCACATTCAGTGCACTGCGGTACCTCAAACTGC
TCAGGGAAGTCCGGCGGCATCCGGTGTCACTGCACCGCTGCGGAACCACACAGTTTATCACGCTGGTGGGCTTCATCGCC
ATGTTCATGGTGCTGTATCTGCTGATGCTTACAAACAGCGGCCCGCATATTCCGCAGGACATCTCCGCCATATCCGGAAC
CATACTTTTTCTCGGAGCCGTCTTTGTATTCATTACGGCACAGGTGACTTCCACAGGGCTGCATACCGCCCTTTCCGCCA
ATGCCTCGCTGCAGCATCAGGCCGTGCACGACTACCTGACGGGGCTGCCCAACCGCCGGCTCATCATGGAACTGCTCGGC
GAAGCCATGCAGACCGCTCCTGCCGGATATGCACTGGTTTTTGTGGATATCATGAACTTTAAACGGGTTAACATCAGCTT
TGCTCATTATGTGGGCGATCAGATTCTGGAGCAGGTCGGGCAGCGTCTCCAGACGTCCATGAAACCCGGCGATGTGGCAG
CCCGTCTCGGCGGTGACGACTTTGCCATCCTGCTGCGCACAGGCAGCCCGCGCGAAGCTGTTCAGCGCACACAGGCGGTC
AAGGCGGCGCTGAAACAACCGTATTTTTCCGGCGATATCCAGTTTTCGCTGGATTGCGGTTTCGGCCTGTATATGGGAAC
CGCGCAGGATACCAGACCCGAACATGTGATTGCCAAAGCCAACACGGCCATGATGCGGGCCAAGCAACGCGGCAGAAACC
GCATTGCCGTATTCAGCCGCTCCATGCAGGACAAAGCCCAGCTCACCATCCATTTTGAAAACCAGTTCCGCCGCAGTCTG
CGCAACGGAGACTTCTTTCTTGTCTTTCAGCCGCAGTACGCCCTTACCCCTCAGCCGGAACTGATAGGCTTTGAAACGCT
TGTCCGCTGGAACCACCCCGAAAGGGGAATAGTGAGTCCTGCCGAATTTGTGCCCATGGCGGAAACCACCGGGCTTATTC
TGCACCTTGACCGCTATGTGCTGCGCGAAGCCTGCCGCATATGGGGAGAAATGCGCGCCAGTCTTCCCGCGTGCCGCGCG
CTGCATTTTTCCGTCAACCTGAGCGCCTCGCACATGGACCGCCCGACCTTTATCCGCAAGCTGGAAAAAACACTGGCGGC
CTTTGAGATGCCGCACGAATCCATCATTCTGGAACTGACTGAATCCGCCCTGATGAGCAATCCGGAAACCGCCGCCCGCA
AAATGCAATATCTGCGCAGCATCGGCCTGCATGTGGCGCTGGACGATTTCGGCACAGGATATTCTTCGCTGGCTTATCTG
ACACGTTTTCCCTGCTACTGCCTGAAAATTGATAAAAGCTTTGTGGACAACATAACCACCGATGAAAACTCCGTGCGTGT
GGTGCGGGCCATCATCCATCTGGCACACGGTCTGGGTATGGTGGCTCTGGCCGAAGGCGTGGAAACACCTGAACAGCTGG
CGCAACTGCAGGATATGGGCTGTGATCAGGTTCAGGGCTATCTGCTGGGCAAGCCTATGCCGCAGGCGGCCCTGCGGGAT
GTCATAGCCCGCAACTGCTGA

Upstream 100 bases:

>100_bases
CACGTGGCGCTGAATTGTATCATCCACGCATACAACAGGGAGAGGACTGCCTCTCCTTTTTTTATGTCTGCGCCACTGTT
CCGGAGCCCGTGACATCCAT

Downstream 100 bases:

>100_bases
CCTGCGCGCGGCAGCAAGCTGCCGGCAGAGCCCGCGACGGGCGCCTGCGGCTTACGGCCCCGTTCATCCGCGGGCAAAAA
AGAACTCCGGCTCCTTGCGC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MTTAGELCIVRQNRIAATPLMNSLQHFLLTPFSASVGCGLLLLTFSALRYLKLLREVRRHPVSLHRCGTTQFITLVGFIA
MFMVLYLLMLTNSGPHIPQDISAISGTILFLGAVFVFITAQVTSTGLHTALSANASLQHQAVHDYLTGLPNRRLIMELLG
EAMQTAPAGYALVFVDIMNFKRVNISFAHYVGDQILEQVGQRLQTSMKPGDVAARLGGDDFAILLRTGSPREAVQRTQAV
KAALKQPYFSGDIQFSLDCGFGLYMGTAQDTRPEHVIAKANTAMMRAKQRGRNRIAVFSRSMQDKAQLTIHFENQFRRSL
RNGDFFLVFQPQYALTPQPELIGFETLVRWNHPERGIVSPAEFVPMAETTGLILHLDRYVLREACRIWGEMRASLPACRA
LHFSVNLSASHMDRPTFIRKLEKTLAAFEMPHESIILELTESALMSNPETAARKMQYLRSIGLHVALDDFGTGYSSLAYL
TRFPCYCLKIDKSFVDNITTDENSVRVVRAIIHLAHGLGMVALAEGVETPEQLAQLQDMGCDQVQGYLLGKPMPQAALRD
VIARNC

Sequences:

>Translated_566_residues
MTTAGELCIVRQNRIAATPLMNSLQHFLLTPFSASVGCGLLLLTFSALRYLKLLREVRRHPVSLHRCGTTQFITLVGFIA
MFMVLYLLMLTNSGPHIPQDISAISGTILFLGAVFVFITAQVTSTGLHTALSANASLQHQAVHDYLTGLPNRRLIMELLG
EAMQTAPAGYALVFVDIMNFKRVNISFAHYVGDQILEQVGQRLQTSMKPGDVAARLGGDDFAILLRTGSPREAVQRTQAV
KAALKQPYFSGDIQFSLDCGFGLYMGTAQDTRPEHVIAKANTAMMRAKQRGRNRIAVFSRSMQDKAQLTIHFENQFRRSL
RNGDFFLVFQPQYALTPQPELIGFETLVRWNHPERGIVSPAEFVPMAETTGLILHLDRYVLREACRIWGEMRASLPACRA
LHFSVNLSASHMDRPTFIRKLEKTLAAFEMPHESIILELTESALMSNPETAARKMQYLRSIGLHVALDDFGTGYSSLAYL
TRFPCYCLKIDKSFVDNITTDENSVRVVRAIIHLAHGLGMVALAEGVETPEQLAQLQDMGCDQVQGYLLGKPMPQAALRD
VIARNC
>Mature_565_residues
TTAGELCIVRQNRIAATPLMNSLQHFLLTPFSASVGCGLLLLTFSALRYLKLLREVRRHPVSLHRCGTTQFITLVGFIAM
FMVLYLLMLTNSGPHIPQDISAISGTILFLGAVFVFITAQVTSTGLHTALSANASLQHQAVHDYLTGLPNRRLIMELLGE
AMQTAPAGYALVFVDIMNFKRVNISFAHYVGDQILEQVGQRLQTSMKPGDVAARLGGDDFAILLRTGSPREAVQRTQAVK
AALKQPYFSGDIQFSLDCGFGLYMGTAQDTRPEHVIAKANTAMMRAKQRGRNRIAVFSRSMQDKAQLTIHFENQFRRSLR
NGDFFLVFQPQYALTPQPELIGFETLVRWNHPERGIVSPAEFVPMAETTGLILHLDRYVLREACRIWGEMRASLPACRAL
HFSVNLSASHMDRPTFIRKLEKTLAAFEMPHESIILELTESALMSNPETAARKMQYLRSIGLHVALDDFGTGYSSLAYLT
RFPCYCLKIDKSFVDNITTDENSVRVVRAIIHLAHGLGMVALAEGVETPEQLAQLQDMGCDQVQGYLLGKPMPQAALRDV
IARNC

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=416, Percent_Identity=34.1346153846154, Blast_Score=245, Evalue=7e-66,
Organism=Escherichia coli, GI87081921, Length=450, Percent_Identity=30, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI226510982, Length=416, Percent_Identity=29.3269230769231, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1788849, Length=431, Percent_Identity=29.4663573085847, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI87081845, Length=250, Percent_Identity=35.2, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788502, Length=236, Percent_Identity=34.3220338983051, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1790496, Length=242, Percent_Identity=35.5371900826446, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI87081980, Length=250, Percent_Identity=37.6, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI1786507, Length=236, Percent_Identity=35.1694915254237, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1787055, Length=264, Percent_Identity=32.1969696969697, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI87082096, Length=439, Percent_Identity=27.3348519362187, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI87081743, Length=242, Percent_Identity=32.2314049586777, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788381, Length=424, Percent_Identity=23.5849056603774, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI87081977, Length=185, Percent_Identity=30.8108108108108, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87082007, Length=206, Percent_Identity=30.0970873786408, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI145693134, Length=172, Percent_Identity=27.906976744186, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87081881, Length=162, Percent_Identity=29.0123456790123, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787262, Length=237, Percent_Identity=24.4725738396624, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789650, Length=459, Percent_Identity=23.0936819172113, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1788085, Length=162, Percent_Identity=28.3950617283951, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787410, Length=149, Percent_Identity=30.8724832214765, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786584, Length=165, Percent_Identity=29.0909090909091, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1787816, Length=156, Percent_Identity=29.4871794871795, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87081974, Length=170, Percent_Identity=27.6470588235294, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788956, Length=131, Percent_Identity=34.3511450381679, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 62964; Mature: 62833

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAGELCIVRQNRIAATPLMNSLQHFLLTPFSASVGCGLLLLTFSALRYLKLLREVRRH
CCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PVSLHRCGTTQFITLVGFIAMFMVLYLLMLTNSGPHIPQDISAISGTILFLGAVFVFITA
CCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QVTSTGLHTALSANASLQHQAVHDYLTGLPNRRLIMELLGEAMQTAPAGYALVFVDIMNF
HHHHCCHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEEHHCC
KRVNISFAHYVGDQILEQVGQRLQTSMKPGDVAARLGGDDFAILLRTGSPREAVQRTQAV
CEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHH
KAALKQPYFSGDIQFSLDCGFGLYMGTAQDTRPEHVIAKANTAMMRAKQRGRNRIAVFSR
HHHHHCCCCCCCEEEEEECCCEEEECCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEHHHH
SMQDKAQLTIHFENQFRRSLRNGDFFLVFQPQYALTPQPELIGFETLVRWNHPERGIVSP
CCCCCEEEEEEEHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCH
AEFVPMAETTGLILHLDRYVLREACRIWGEMRASLPACRALHFSVNLSASHMDRPTFIRK
HHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEEEECCHHHCCCHHHHHH
LEKTLAAFEMPHESIILELTESALMSNPETAARKMQYLRSIGLHVALDDFGTGYSSLAYL
HHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHH
TRFPCYCLKIDKSFVDNITTDENSVRVVRAIIHLAHGLGMVALAEGVETPEQLAQLQDMG
HHCCHHEEEECHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHCC
CDQVQGYLLGKPMPQAALRDVIARNC
HHHHCCEECCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TTAGELCIVRQNRIAATPLMNSLQHFLLTPFSASVGCGLLLLTFSALRYLKLLREVRRH
CCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PVSLHRCGTTQFITLVGFIAMFMVLYLLMLTNSGPHIPQDISAISGTILFLGAVFVFITA
CCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QVTSTGLHTALSANASLQHQAVHDYLTGLPNRRLIMELLGEAMQTAPAGYALVFVDIMNF
HHHHCCHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEEHHCC
KRVNISFAHYVGDQILEQVGQRLQTSMKPGDVAARLGGDDFAILLRTGSPREAVQRTQAV
CEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHH
KAALKQPYFSGDIQFSLDCGFGLYMGTAQDTRPEHVIAKANTAMMRAKQRGRNRIAVFSR
HHHHHCCCCCCCEEEEEECCCEEEECCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEHHHH
SMQDKAQLTIHFENQFRRSLRNGDFFLVFQPQYALTPQPELIGFETLVRWNHPERGIVSP
CCCCCEEEEEEEHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCH
AEFVPMAETTGLILHLDRYVLREACRIWGEMRASLPACRALHFSVNLSASHMDRPTFIRK
HHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEEEECCHHHCCCHHHHHH
LEKTLAAFEMPHESIILELTESALMSNPETAARKMQYLRSIGLHVALDDFGTGYSSLAYL
HHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHH
TRFPCYCLKIDKSFVDNITTDENSVRVVRAIIHLAHGLGMVALAEGVETPEQLAQLQDMG
HHCCHHEEEECHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHCC
CDQVQGYLLGKPMPQAALRDVIARNC
HHHHCCEECCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]