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The map label for this gene is livK [C]

Identifier: 78357810

GI number: 78357810

Start: 2768399

End: 2769652

Strand: Direct

Name: livK [C]

Synonym: Dde_2768

Alternate gene names: 78357810

Gene position: 2768399-2769652 (Clockwise)

Preceding gene: 78357807

Following gene: 78357811

Centisome position: 74.22

GC content: 63.56

Gene sequence:

>1254_bases
ATGGGGGGACGCAGTACGGTATATTCTGTCCGGTACAGGGCCGCAGATGTTCTGACGGCAGCCCTGCTGGCTGTGCTGTG
CCTTGCGGCTGCTCTTCCGGCCTTTGCCGGCGGCAGACAGGGTCCGGCAGTGCTGGGCATAGCCGCCGTATCCCCCGTGA
CCGACCCCGCCGAAGTATCTTTCCAGCACGGAGTGCGTGTTGCCGTGGCCGTGTTCAACTCTCTGGGCGGACTCATGGGG
CAGCCGATACGCACCGTGCTCATTCCGCTGGGGTCTTCTCCGCTGGAAGCACGCCATGCCGCCAGACAACTGGTGCATAC
ACCGCCGCTGGGCATCATCGGGCCGTCTGCCAGCACGCAGGCCCTTGCCATGGCCGAAGTGCTGGACCGCGCGCGTATAC
CCACCATCACGCCTTCGGCATCCCACCCGCTTGTCATCCGCGGCAGGCCGTACATTTTCCGCATCTGCAACGGCGACACA
GCCAACGCCAACGCCATGGCGCGGTTCATCACGCGGCATCTGGGACTTTCACGCGTGGCCGTCATAACCAACATCAGCAG
CGATTACAGCATTTCCATGTCGGAATCGTTTGTGGATGAAGCCATCAGGCAGGGCGGTGAAGTCGTCTGGCGGGGACAAT
ATCTGGACCGTCAGCAGGATTTTTCCGTCATTATACACCAGTTGCTGCGGCTGAAGCCGGAATGCGTCTTCCTGCCCGAC
TTCATGCGTTCCAGCGGACTGTTCATGCAGCAGGCCGCCGGCATGGGGCTGAAGACAGTATTTGCAGGGGGCGATGCATG
GGACGCCACCCTGCCCCGCTACGCGGCCGCCGCTGCGGAAAATGCCTATTATATGGCACAATGGATACCCGAAGAACCGG
CCGGTGCCGCAAAAAACCATCATGACCGGTGCCGCGGGCATATCACTCCCATGCGTGCATTCTGCAAGGCACCGTGGCTG
CTGGCCCGCACCCATGCCTTGCGTTATCTGGGCAGAGACTTTGCCGGCAGTCTGGAAGCGCTGGGCTACGATGCGGCCTG
TGTGCTGCTGGCCGCCGCCCGCCGTGCGGGTTCGTGCGACCCGCGCGCGGTGCGCGAAGCTCTGGCGCAGACATACTGGC
ACGGGCTGACCGGTCCGCTGCACTTTGACGCCGACGGTGCACCGCCCCCCGGACCTGTTCATATCCTGCAGCTGCGCAAC
GGTTCGGCCCGGCCGGTACAGACTGTCACGCTTTCCCCGCGGGAGGCTCAATGA

Upstream 100 bases:

>100_bases
TCATTTGGCATACTCCACCAGTCAAGGCAAGCATCTAACCCTCTTGCCTGATTCCGCCAATGCATGTATTAAGAATGATT
CTTTTTTGTGGGGAGTGACA

Downstream 100 bases:

>100_bases
ACCGAACCCCTCTCAAACGCAGATTCACCGTCACCCTCATGCTGTTCACCCTGCTGTGCTGTGCTCTGTACACTGTGACG
GCAAGCAGTTTCATGCATTA

Product: ABC-type branched-chain amino acid transport systems periplasmic component-like

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MGGRSTVYSVRYRAADVLTAALLAVLCLAAALPAFAGGRQGPAVLGIAAVSPVTDPAEVSFQHGVRVAVAVFNSLGGLMG
QPIRTVLIPLGSSPLEARHAARQLVHTPPLGIIGPSASTQALAMAEVLDRARIPTITPSASHPLVIRGRPYIFRICNGDT
ANANAMARFITRHLGLSRVAVITNISSDYSISMSESFVDEAIRQGGEVVWRGQYLDRQQDFSVIIHQLLRLKPECVFLPD
FMRSSGLFMQQAAGMGLKTVFAGGDAWDATLPRYAAAAAENAYYMAQWIPEEPAGAAKNHHDRCRGHITPMRAFCKAPWL
LARTHALRYLGRDFAGSLEALGYDAACVLLAAARRAGSCDPRAVREALAQTYWHGLTGPLHFDADGAPPPGPVHILQLRN
GSARPVQTVTLSPREAQ

Sequences:

>Translated_417_residues
MGGRSTVYSVRYRAADVLTAALLAVLCLAAALPAFAGGRQGPAVLGIAAVSPVTDPAEVSFQHGVRVAVAVFNSLGGLMG
QPIRTVLIPLGSSPLEARHAARQLVHTPPLGIIGPSASTQALAMAEVLDRARIPTITPSASHPLVIRGRPYIFRICNGDT
ANANAMARFITRHLGLSRVAVITNISSDYSISMSESFVDEAIRQGGEVVWRGQYLDRQQDFSVIIHQLLRLKPECVFLPD
FMRSSGLFMQQAAGMGLKTVFAGGDAWDATLPRYAAAAAENAYYMAQWIPEEPAGAAKNHHDRCRGHITPMRAFCKAPWL
LARTHALRYLGRDFAGSLEALGYDAACVLLAAARRAGSCDPRAVREALAQTYWHGLTGPLHFDADGAPPPGPVHILQLRN
GSARPVQTVTLSPREAQ
>Mature_416_residues
GGRSTVYSVRYRAADVLTAALLAVLCLAAALPAFAGGRQGPAVLGIAAVSPVTDPAEVSFQHGVRVAVAVFNSLGGLMGQ
PIRTVLIPLGSSPLEARHAARQLVHTPPLGIIGPSASTQALAMAEVLDRARIPTITPSASHPLVIRGRPYIFRICNGDTA
NANAMARFITRHLGLSRVAVITNISSDYSISMSESFVDEAIRQGGEVVWRGQYLDRQQDFSVIIHQLLRLKPECVFLPDF
MRSSGLFMQQAAGMGLKTVFAGGDAWDATLPRYAAAAAENAYYMAQWIPEEPAGAAKNHHDRCRGHITPMRAFCKAPWLL
ARTHALRYLGRDFAGSLEALGYDAACVLLAAARRAGSCDPRAVREALAQTYWHGLTGPLHFDADGAPPPGPVHILQLRNG
SARPVQTVTLSPREAQ

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Escherichia coli, GI1789867, Length=347, Percent_Identity=24.7838616714697, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI48994941, Length=249, Percent_Identity=24.8995983935743, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 44636; Mature: 44505

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGRSTVYSVRYRAADVLTAALLAVLCLAAALPAFAGGRQGPAVLGIAAVSPVTDPAEVS
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHH
FQHGVRVAVAVFNSLGGLMGQPIRTVLIPLGSSPLEARHAARQLVHTPPLGIIGPSASTQ
HHCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEECCCCCHH
ALAMAEVLDRARIPTITPSASHPLVIRGRPYIFRICNGDTANANAMARFITRHLGLSRVA
HHHHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHHHCCHHEE
VITNISSDYSISMSESFVDEAIRQGGEVVWRGQYLDRQQDFSVIIHQLLRLKPECVFLPD
EEEECCCCCEEEHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEECCH
FMRSSGLFMQQAAGMGLKTVFAGGDAWDATLPRYAAAAAENAYYMAQWIPEEPAGAAKNH
HHCCCCCHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCC
HDRCRGHITPMRAFCKAPWLLARTHALRYLGRDFAGSLEALGYDAACVLLAAARRAGSCD
HHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHCCCCC
PRAVREALAQTYWHGLTGPLHFDADGAPPPGPVHILQLRNGSARPVQTVTLSPREAQ
HHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
GGRSTVYSVRYRAADVLTAALLAVLCLAAALPAFAGGRQGPAVLGIAAVSPVTDPAEVS
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHH
FQHGVRVAVAVFNSLGGLMGQPIRTVLIPLGSSPLEARHAARQLVHTPPLGIIGPSASTQ
HHCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEECCCCCHH
ALAMAEVLDRARIPTITPSASHPLVIRGRPYIFRICNGDTANANAMARFITRHLGLSRVA
HHHHHHHHHHCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHHHCCHHEE
VITNISSDYSISMSESFVDEAIRQGGEVVWRGQYLDRQQDFSVIIHQLLRLKPECVFLPD
EEEECCCCCEEEHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEECCH
FMRSSGLFMQQAAGMGLKTVFAGGDAWDATLPRYAAAAAENAYYMAQWIPEEPAGAAKNH
HHCCCCCHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCC
HDRCRGHITPMRAFCKAPWLLARTHALRYLGRDFAGSLEALGYDAACVLLAAARRAGSCD
HHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHCCCCC
PRAVREALAQTYWHGLTGPLHFDADGAPPPGPVHILQLRNGSARPVQTVTLSPREAQ
HHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]