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The map label for this gene is 78357786

Identifier: 78357786

GI number: 78357786

Start: 2747502

End: 2748614

Strand: Direct

Name: 78357786

Synonym: Dde_2744

Alternate gene names: NA

Gene position: 2747502-2748614 (Clockwise)

Preceding gene: 78357785

Following gene: 78357788

Centisome position: 73.65

GC content: 64.06

Gene sequence:

>1113_bases
ATGAACGCTTACACTGAAATTCCCATGGTTCCGGGGCCCACCACCCTGCACCCCGATGCACTGGCGGCCATGGGCCGTGA
TTACGGTTCAGGACAGATAGAAACTGCCTACCTGCAGCTGTATGCAGACACGCAGAAACTGCTGGGCACGCTGGCGGGTA
CCGGCAACGATATGGTGATAATGACCGGCGAAGGCATGCTGGCCCTGTGGGGAGCGCTGAAGAGCTGTCTGGCTCCCGGT
GACAGGGTGCTCAGCGTGGCCACAGGCGTCTTCGGCGACGGCATAGGCGACATGGCCGCCGGTCTGGGCTGCGAAGTGCG
CAAAATCACACTGCCCTTCAACGCCACGCTGGACGACCTGACCGCCGTGGAAGAGGCTGTCGACCGTTTCAGGCCGCGCA
TGATCACCGCCGTGCACTGTGAAACGCCGTCCGGCACGCTGAACCCGCTGGCAGAACTGGGCAGGCTCAAAGCAGCCATG
AATGTTCCGCTTTTCTATGTTGACGCCGTGGCAAGCCTTGGCGGCGCTCCCGTAATGGCCGACGACTGGCATGTGGACCT
GCTGCTCGGCGGCTCGCAGAAATGCCTCTCCGCACCGCCTTCCATGGCCTTTGTGGGAGTAAGCCCCGCCGCATGGGAGG
CAGTGGAACAGCGGGCCTATCAGGGCTACGACGCACTGGGACCTTTCCGTACAGTGCACAGCGACGGCCGCTGCCCGTAT
ACCCCGTACTGGCACGGCACGGCGGCGCTGCATGCCGCCGCCGCGGCCATTGTTGCCGAAGGAACCGAACAGGTTTTTGC
GCGGCACCGCAATGTGGCCCGGCAATGCCGCGACGGTCTGCAGGAGATGGACATCAGGTTGTTCACCGCTGAAAACGCTG
TGAATTCACCCACAGTAACCGCGGCACTGGTTCCCCGAGGCTGGGAATGCGCTGCATGGCTGCAGGCGCTTGCCGCACGC
GGTCTGCGCGCCGCAGGCAGCTTCGGCCCCATGGCGGGCAAGGTGTTCCGGCTGGGGCATATGGGTACACAGGCACATCC
CCGGCTGATGGAAAAAGCCCTGCAGGTCATGGCGCAGGTGCTGGAACAGGGTCCGGCGGCATCCCGCCGCTGA

Upstream 100 bases:

>100_bases
GTTTTTCACGCACCGGCGGTCTTTTTCTGGGTACTCCGGTCGCCCCCGACGAAGTGGAACTGGTGGACCTGTAACAACCG
GCAACGCCGGAGGAAACGGC

Downstream 100 bases:

>100_bases
CGCTGCGCACATGGTTATCTGAAAAAATGTCCGGCACGGCGTACAAGCTGCGCCGGACTTTTTTTCACTCCCGCGCCGGC
CGCGCGCAGGCAAAAGCAGT

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MNAYTEIPMVPGPTTLHPDALAAMGRDYGSGQIETAYLQLYADTQKLLGTLAGTGNDMVIMTGEGMLALWGALKSCLAPG
DRVLSVATGVFGDGIGDMAAGLGCEVRKITLPFNATLDDLTAVEEAVDRFRPRMITAVHCETPSGTLNPLAELGRLKAAM
NVPLFYVDAVASLGGAPVMADDWHVDLLLGGSQKCLSAPPSMAFVGVSPAAWEAVEQRAYQGYDALGPFRTVHSDGRCPY
TPYWHGTAALHAAAAAIVAEGTEQVFARHRNVARQCRDGLQEMDIRLFTAENAVNSPTVTAALVPRGWECAAWLQALAAR
GLRAAGSFGPMAGKVFRLGHMGTQAHPRLMEKALQVMAQVLEQGPAASRR

Sequences:

>Translated_370_residues
MNAYTEIPMVPGPTTLHPDALAAMGRDYGSGQIETAYLQLYADTQKLLGTLAGTGNDMVIMTGEGMLALWGALKSCLAPG
DRVLSVATGVFGDGIGDMAAGLGCEVRKITLPFNATLDDLTAVEEAVDRFRPRMITAVHCETPSGTLNPLAELGRLKAAM
NVPLFYVDAVASLGGAPVMADDWHVDLLLGGSQKCLSAPPSMAFVGVSPAAWEAVEQRAYQGYDALGPFRTVHSDGRCPY
TPYWHGTAALHAAAAAIVAEGTEQVFARHRNVARQCRDGLQEMDIRLFTAENAVNSPTVTAALVPRGWECAAWLQALAAR
GLRAAGSFGPMAGKVFRLGHMGTQAHPRLMEKALQVMAQVLEQGPAASRR
>Mature_370_residues
MNAYTEIPMVPGPTTLHPDALAAMGRDYGSGQIETAYLQLYADTQKLLGTLAGTGNDMVIMTGEGMLALWGALKSCLAPG
DRVLSVATGVFGDGIGDMAAGLGCEVRKITLPFNATLDDLTAVEEAVDRFRPRMITAVHCETPSGTLNPLAELGRLKAAM
NVPLFYVDAVASLGGAPVMADDWHVDLLLGGSQKCLSAPPSMAFVGVSPAAWEAVEQRAYQGYDALGPFRTVHSDGRCPY
TPYWHGTAALHAAAAAIVAEGTEQVFARHRNVARQCRDGLQEMDIRLFTAENAVNSPTVTAALVPRGWECAAWLQALAAR
GLRAAGSFGPMAGKVFRLGHMGTQAHPRLMEKALQVMAQVLEQGPAASRR

Specific function: Unknown

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=364, Percent_Identity=28.2967032967033, Blast_Score=135, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17536281, Length=362, Percent_Identity=27.9005524861878, Blast_Score=142, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6321079, Length=371, Percent_Identity=23.989218328841, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17530823, Length=365, Percent_Identity=27.3972602739726, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 39204; Mature: 39204

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAYTEIPMVPGPTTLHPDALAAMGRDYGSGQIETAYLQLYADTQKLLGTLAGTGNDMVI
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEEEHHHHHHHHHHHCCCCCCEEE
MTGEGMLALWGALKSCLAPGDRVLSVATGVFGDGIGDMAAGLGCEVRKITLPFNATLDDL
EECCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCEEEEEEECCCCCHHHH
TAVEEAVDRFRPRMITAVHCETPSGTLNPLAELGRLKAAMNVPLFYVDAVASLGGAPVMA
HHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEE
DDWHVDLLLGGSQKCLSAPPSMAFVGVSPAAWEAVEQRAYQGYDALGPFRTVHSDGRCPY
CCCEEEEEECCCHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCC
TPYWHGTAALHAAAAAIVAEGTEQVFARHRNVARQCRDGLQEMDIRLFTAENAVNSPTVT
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEE
AALVPRGWECAAWLQALAARGLRAAGSFGPMAGKVFRLGHMGTQAHPRLMEKALQVMAQV
EEECCCCCHHHHHHHHHHHCCCHHCCCCCCCCHHHEEECCCCCCCCHHHHHHHHHHHHHH
LEQGPAASRR
HHCCCCCCCC
>Mature Secondary Structure
MNAYTEIPMVPGPTTLHPDALAAMGRDYGSGQIETAYLQLYADTQKLLGTLAGTGNDMVI
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEEEHHHHHHHHHHHCCCCCCEEE
MTGEGMLALWGALKSCLAPGDRVLSVATGVFGDGIGDMAAGLGCEVRKITLPFNATLDDL
EECCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCEEEEEEECCCCCHHHH
TAVEEAVDRFRPRMITAVHCETPSGTLNPLAELGRLKAAMNVPLFYVDAVASLGGAPVMA
HHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEE
DDWHVDLLLGGSQKCLSAPPSMAFVGVSPAAWEAVEQRAYQGYDALGPFRTVHSDGRCPY
CCCEEEEEECCCHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCC
TPYWHGTAALHAAAAAIVAEGTEQVFARHRNVARQCRDGLQEMDIRLFTAENAVNSPTVT
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEE
AALVPRGWECAAWLQALAARGLRAAGSFGPMAGKVFRLGHMGTQAHPRLMEKALQVMAQV
EEECCCCCHHHHHHHHHHHCCCHHCCCCCCCCHHHEEECCCCCCCCHHHHHHHHHHHHHH
LEQGPAASRR
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]