Click here to switch to the map view.

The map label for this gene is aroL

Identifier: 78357770

GI number: 78357770

Start: 2730262

End: 2730804

Strand: Reverse

Name: aroL

Synonym: Dde_2728

Alternate gene names: 78357770

Gene position: 2730804-2730262 (Counterclockwise)

Preceding gene: 78357775

Following gene: 78357769

Centisome position: 73.21

GC content: 67.77

Gene sequence:

>543_bases
ATGCGCGGTGCAGGCGGAGGTAGGATGGAGCGTATTTTTCTGATCGGGGCGCGGGCCAGCGGCAAAACGACGGCGGGCCG
TATTCTGGCGGAAAAACTGGGCTGGCGGTGTGCTGATACCGATGAGATGGTGCAGCGCAGGGCAGGGTGCAGCATTGCGG
ACATGGTGGCCCGCGACGGGTGGCCGGTGTTCCGTGAGGCGGAAGCCGGGGCGCTGCAGGCGGCGTGTGCGCTGACACGG
GTGGTGGTCTCTACCGGCGGCGGCATGGTGCTGCGCGCGGATAACCGCGCGGCGCTGCGCGAGGGGGGCATTGTGTTTTA
TCTGTGCGCTCCTGCGGCTGTTCTGGCATCCAGACTGGTGCTGGACCCTGTGGTCTCGCAGCGGCCTTCGCTGACAGGGG
GGAACCCTGCGGCCGAGATTGCCGCCGTGCTGGCGGAACGCGATACCCTGTACCGCGAGACGGCGCATCATGTGGTGGAT
GCCTGTCAGCCTGCCGCAGCGGTTGCCGGACAGATGCTGCGGCTGCTGGCTGCCGCGGGATGA

Upstream 100 bases:

>100_bases
CGCGTTTCGGCGTATGTCATAGCATACCTGCATTGACGGGTATTTGAAAGAGACAAAGCACACTTGTTACGGGCGTCCGG
GTGCGGATGGTACAGGCCGC

Downstream 100 bases:

>100_bases
CTGCTGCCGGATGACCGGCGCGGACACTGTACGCGTGACGCCCCGTGGGGTATGCTGTGGCTGTACCGCCTGCATGGCAG
GCAGAGGCGTTTCTGCCGGT

Product: shikimate kinase II

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MRGAGGGRMERIFLIGARASGKTTAGRILAEKLGWRCADTDEMVQRRAGCSIADMVARDGWPVFREAEAGALQAACALTR
VVVSTGGGMVLRADNRAALREGGIVFYLCAPAAVLASRLVLDPVVSQRPSLTGGNPAAEIAAVLAERDTLYRETAHHVVD
ACQPAAAVAGQMLRLLAAAG

Sequences:

>Translated_180_residues
MRGAGGGRMERIFLIGARASGKTTAGRILAEKLGWRCADTDEMVQRRAGCSIADMVARDGWPVFREAEAGALQAACALTR
VVVSTGGGMVLRADNRAALREGGIVFYLCAPAAVLASRLVLDPVVSQRPSLTGGNPAAEIAAVLAERDTLYRETAHHVVD
ACQPAAAVAGQMLRLLAAAG
>Mature_180_residues
MRGAGGGRMERIFLIGARASGKTTAGRILAEKLGWRCADTDEMVQRRAGCSIADMVARDGWPVFREAEAGALQAACALTR
VVVSTGGGMVLRADNRAALREGGIVFYLCAPAAVLASRLVLDPVVSQRPSLTGGNPAAEIAAVLAERDTLYRETAHHVVD
ACQPAAAVAGQMLRLLAAAG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fifth step. [C]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI1786587, Length=166, Percent_Identity=43.3734939759036, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87082255, Length=169, Percent_Identity=31.3609467455621, Blast_Score=79, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320332, Length=171, Percent_Identity=31.5789473684211, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROK_DESDG (Q30XS2)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_389219.1
- ProteinModelPortal:   Q30XS2
- SMR:   Q30XS2
- STRING:   Q30XS2
- GeneID:   3757751
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_2728
- NMPDR:   fig|207559.3.peg.3135
- eggNOG:   COG0703
- HOGENOM:   HBG335815
- OMA:   GGMVLAE
- ProtClustDB:   PRK03731
- BioCyc:   DDES207559:DDE_2728-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 18714; Mature: 18714

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGAGGGRMERIFLIGARASGKTTAGRILAEKLGWRCADTDEMVQRRAGCSIADMVARDG
CCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHCCC
WPVFREAEAGALQAACALTRVVVSTGGGMVLRADNRAALREGGIVFYLCAPAAVLASRLV
CCCHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCEEEEECCCHHHHHHHHH
LDPVVSQRPSLTGGNPAAEIAAVLAERDTLYRETAHHVVDACQPAAAVAGQMLRLLAAAG
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRGAGGGRMERIFLIGARASGKTTAGRILAEKLGWRCADTDEMVQRRAGCSIADMVARDG
CCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHCCC
WPVFREAEAGALQAACALTRVVVSTGGGMVLRADNRAALREGGIVFYLCAPAAVLASRLV
CCCHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCEEEEECCCHHHHHHHHH
LDPVVSQRPSLTGGNPAAEIAAVLAERDTLYRETAHHVVDACQPAAAVAGQMLRLLAAAG
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA