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The map label for this gene is aroC

Identifier: 78357768

GI number: 78357768

Start: 2728462

End: 2729529

Strand: Reverse

Name: aroC

Synonym: Dde_2726

Alternate gene names: 78357768

Gene position: 2729529-2728462 (Counterclockwise)

Preceding gene: 78357769

Following gene: 78357767

Centisome position: 73.17

GC content: 63.48

Gene sequence:

>1068_bases
ATGAGCGGCAGTACCTTTGGCCGTGTTTTCAGACTGACGACCTACGGCGAATCGCACGGTGCCGGTCTGGGTGGCGTGGT
GGACGGCTGTCCGGCGGGAATTGCCCTGACGGAAGCCATGATTCAGGCCGAGCTTGACCGCCGCAGACCCGGGCAGGGCG
GCCCCGCCGCCACGGCGCGTAAAGAGCCTGACAGAGTGCGGCTGCTTTCCGGCGTGTTCGAGGGCCGGACAACGGGCACT
CCTGTGGCGTTTCATGTGGAAAATACGGACCAGCGTTCCCGCGATTACGGCGATATAATGCACGTTTACCGTCCGGGGCA
TGCCGATGTCACATATGATGCCAAGTACGGCCGGCGCGACTACCGTGGCGGCGGACGTTCGTCAGGCCGCGAGACGCTTT
CACGCGTGGCGGGCGGTGCGGTGGCGCAGGCGCTGCTGGCGGAATGCGGCATAACCGTCAATGCCTTTACCGTGGAATTG
GGCGGTGTGCCCGCGCGGCCGGAAGACCCCGCAGGGGCGCAGGACAGACCTTTTTTTGCGCCGGAAGAAGACATTGTGGC
GCAGTGGGATGCTCTGGTGCGCAACGTGAAGGGCAGGGGCGATACGGTGGGCGGCATCGTGCAGGTTGAAGCTTACGGAG
TTCCCGCCGGTCTGGGCGAGCCTGTGTTTGACAGGCTTGATGCGCGCCTTGCCTGTGCGCTTATGTCGGTGGGTGCCGTA
AAAGGGGTGGAAATAGGAGCGGGGTTTGCCGCAGCCCGTCTGACGGGCAGCAGCAACAACGACGCCATGACCGCCCGCGG
ATACGCCGGAAACAATGCCGGCGGTATTCTGGGCGGTATTTCGTCAGGGCAGACCGTTGTGGCCCGCGCCGCCGTCAAGC
CCATTCCTTCCGTCGCGCAGGAGCAGCACACGGTGGATGATTCCGGCCGCGAAGTTATTCTGCGTGTGGGCGGCAGACAC
GATATAAGTGCTATACCGCGCATTGTGCCTGTTCTTAAAGCCATGACCGCACTGACACTGGCCGACATGCTGCTGATGCA
GCGCCGTATGACCGCCGTGCGTGCATAA

Upstream 100 bases:

>100_bases
GCCTGCTTGCGGGATATGTTTCGTGCGTCCGGACCGTGCGCCGTCTGCGCGGCGTATGTTCCGGCCGCACGTATTCTTTT
TTTCTGATTCCGGAGGAACA

Downstream 100 bases:

>100_bases
GGCGTCCCGCCGCGAGAAGCGCAGTAACACCTTGACGGCATGTCGGGTACCGCCCATACCGGCAGAAAACATAACATCAA
ATAATCGACGGCTGATGCCG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSGSTFGRVFRLTTYGESHGAGLGGVVDGCPAGIALTEAMIQAELDRRRPGQGGPAATARKEPDRVRLLSGVFEGRTTGT
PVAFHVENTDQRSRDYGDIMHVYRPGHADVTYDAKYGRRDYRGGGRSSGRETLSRVAGGAVAQALLAECGITVNAFTVEL
GGVPARPEDPAGAQDRPFFAPEEDIVAQWDALVRNVKGRGDTVGGIVQVEAYGVPAGLGEPVFDRLDARLACALMSVGAV
KGVEIGAGFAAARLTGSSNNDAMTARGYAGNNAGGILGGISSGQTVVARAAVKPIPSVAQEQHTVDDSGREVILRVGGRH
DISAIPRIVPVLKAMTALTLADMLLMQRRMTAVRA

Sequences:

>Translated_355_residues
MSGSTFGRVFRLTTYGESHGAGLGGVVDGCPAGIALTEAMIQAELDRRRPGQGGPAATARKEPDRVRLLSGVFEGRTTGT
PVAFHVENTDQRSRDYGDIMHVYRPGHADVTYDAKYGRRDYRGGGRSSGRETLSRVAGGAVAQALLAECGITVNAFTVEL
GGVPARPEDPAGAQDRPFFAPEEDIVAQWDALVRNVKGRGDTVGGIVQVEAYGVPAGLGEPVFDRLDARLACALMSVGAV
KGVEIGAGFAAARLTGSSNNDAMTARGYAGNNAGGILGGISSGQTVVARAAVKPIPSVAQEQHTVDDSGREVILRVGGRH
DISAIPRIVPVLKAMTALTLADMLLMQRRMTAVRA
>Mature_354_residues
SGSTFGRVFRLTTYGESHGAGLGGVVDGCPAGIALTEAMIQAELDRRRPGQGGPAATARKEPDRVRLLSGVFEGRTTGTP
VAFHVENTDQRSRDYGDIMHVYRPGHADVTYDAKYGRRDYRGGGRSSGRETLSRVAGGAVAQALLAECGITVNAFTVELG
GVPARPEDPAGAQDRPFFAPEEDIVAQWDALVRNVKGRGDTVGGIVQVEAYGVPAGLGEPVFDRLDARLACALMSVGAVK
GVEIGAGFAAARLTGSSNNDAMTARGYAGNNAGGILGGISSGQTVVARAAVKPIPSVAQEQHTVDDSGREVILRVGGRHD
ISAIPRIVPVLKAMTALTLADMLLMQRRMTAVRA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=353, Percent_Identity=54.1076487252125, Blast_Score=343, Evalue=9e-96,
Organism=Saccharomyces cerevisiae, GI6321290, Length=366, Percent_Identity=42.0765027322404, Blast_Score=283, Evalue=2e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_DESDG (Q30XS4)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_389217.1
- HSSP:   P63611
- ProteinModelPortal:   Q30XS4
- SMR:   Q30XS4
- STRING:   Q30XS4
- GeneID:   3757749
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_2726
- NMPDR:   fig|207559.3.peg.3133
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- BioCyc:   DDES207559:DDE_2726-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 37064; Mature: 36933

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSTFGRVFRLTTYGESHGAGLGGVVDGCPAGIALTEAMIQAELDRRRPGQGGPAATAR
CCCCCCEEEEEEEECCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
KEPDRVRLLSGVFEGRTTGTPVAFHVENTDQRSRDYGDIMHVYRPGHADVTYDAKYGRRD
CCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHCCHHHHHHHEECCCCCCEEECCCCCCCC
YRGGGRSSGRETLSRVAGGAVAQALLAECGITVNAFTVELGGVPARPEDPAGAQDRPFFA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCC
PEEDIVAQWDALVRNVKGRGDTVGGIVQVEAYGVPAGLGEPVFDRLDARLACALMSVGAV
CCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCC
KGVEIGAGFAAARLTGSSNNDAMTARGYAGNNAGGILGGISSGQTVVARAAVKPIPSVAQ
CCEEECCCEEEEEEECCCCCCCEEECCCCCCCCCCEEECCCCCCHHHHHHHHCCCHHHHH
EQHTVDDSGREVILRVGGRHDISAIPRIVPVLKAMTALTLADMLLMQRRMTAVRA
HHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGSTFGRVFRLTTYGESHGAGLGGVVDGCPAGIALTEAMIQAELDRRRPGQGGPAATAR
CCCCCEEEEEEEECCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
KEPDRVRLLSGVFEGRTTGTPVAFHVENTDQRSRDYGDIMHVYRPGHADVTYDAKYGRRD
CCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHCCHHHHHHHEECCCCCCEEECCCCCCCC
YRGGGRSSGRETLSRVAGGAVAQALLAECGITVNAFTVELGGVPARPEDPAGAQDRPFFA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCC
PEEDIVAQWDALVRNVKGRGDTVGGIVQVEAYGVPAGLGEPVFDRLDARLACALMSVGAV
CCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCC
KGVEIGAGFAAARLTGSSNNDAMTARGYAGNNAGGILGGISSGQTVVARAAVKPIPSVAQ
CCEEECCCEEEEEEECCCCCCCEEECCCCCCCCCCEEECCCCCCHHHHHHHHCCCHHHHH
EQHTVDDSGREVILRVGGRHDISAIPRIVPVLKAMTALTLADMLLMQRRMTAVRA
HHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA