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The map label for this gene is pheT

Identifier: 78357676

GI number: 78357676

Start: 2650225

End: 2652627

Strand: Reverse

Name: pheT

Synonym: Dde_2634

Alternate gene names: 78357676

Gene position: 2652627-2650225 (Counterclockwise)

Preceding gene: 78357677

Following gene: 78357675

Centisome position: 71.11

GC content: 60.63

Gene sequence:

>2403_bases
ATGCTTCTTAGTCTTAATTGGCTGCGGGAATTTGTTCCCTATACAGGCACGGCACAGGAGCTGGGCGACCGGCTGACCAT
GCTGGGTCTTGAGCTTGAGGAAATTATCCGCCCGTTCGACGCCATAGCCGACATAGTAGTGGGCCATGTGCTTGAATGCG
GCCGCCACCCCGAAGCGGACAAGCTGTCCGTGTGCAGGGTGGACGTAGGCACCGAGGTGCTGGATATCGTGTGCGGCGCG
CCCAACGTGGCTGCCGGACAGAAGGTGCCGGTGGCCAAAGTGGGCGTCACCATGCCTTCCGGATTGAAAATCAAAAAAGC
CAAGCTGCGCGGACAGCCTTCCTGCGGGATGATCTGTTCCGAATCCGAGCTTGAGCTTTCCGACGAATCCGACGGCATCA
TGGTGTTGCCGCAGGATTCTGTACCCGGCGTGCGGCTGGTCGACCTGCTGCAGCTTGACGACACGGTGCTCGATATCAGC
ATCACCCCCAACAGGGCAGACTGCCTTTCTGTTCTGGGGCTGGCACGCGAAGTGGCGCTTGCCTTTGATCTGCCGCTGAC
CATGCCGCAGCTTGAACTGCGCGAACAGGGCGAAGACGCCGGCAGTGACGTGACCATAGCCATTGCAGACGGTGCGCAGT
GCCCAGTGTATCAGGGCCGCATCATCGAAGGTATCAGCACCTGTCCTTCTCCGCTCTGGATGCGCCACCGGCTCAAGTCG
GTGGGTGTGCGTCCCATTTCCGCCATTGTGGATGTGACCAACTATATTCTTATGGAACTCGGCCAGCCGCTGCATGCCTT
TGACCTTGACCTGCTTGAAGGGGCACGCATCGTCGTGGAAACGGCGGCGGAGGGTGAGCGCTTTACCACTCTGGACGGTC
AGGAACGGGTGCTCAAGGCATCGGACCTGCTCATCAGGGACGGCGCCAAAGCCGTGGCGCTGGCCGGTGTGATGGGCGGA
GCCAACACTGAAATCAACGATGCCAGCCGTAGGGTGTTTCTGGAATGCGCCGTCTTCAAACCGGCCACCATTCGCAGAAC
GGCCCGCAGGCTGGGGCTGAGCAGTGAATCTTCCTACCGGTTCGAGCGCGGTGTGGATCAGGTGCTTTCCACATTTGCCA
TGAACCGCGCAGCCCAGCTGATGTGCGAACTGAGCGGTGGCGTGCTGCGTCCCGGCGTATGCCGTGCAGAGCCCGCTCCG
TGGCAGGCTGCACAGCTGCGGTTCCGCCCCGCCCGTGCTGCAGCGCTTCTGGGCATATCGCTTGATGACGGCTTCTGCCG
TGAAACGCTGCAGAAGCTCGGATGCACGCTGAGCGGTGCTGATACGCCCGAATGGACGGTAACCGCCCCCAGTCACCGGC
ACGACCTTGAACGCGAAGCCGACCTGATAGAAGAAGTCGGCCGTGTTTACGGTATGGACAACATTCCTCCCGTGCTGCCC
AAAGTTTCCAAGCCGCTGGAGCAGGGCCGTACGGACAGCGAATATGAATTCTGGGCGCGTATCAAGGCATGGGGCCGCGG
TCTGGGGCTTAACGAGGCTGTGAACTACAGCTTTGTGGGGCACAAGGATCTTGATTTTCTCGGCCTGCCTGCCGGCAACC
GCATATCCATCATGAATCCGCTGACCTCGGAGCAGGACGTGCTGCGCACAGAACTTGCTCCCGGTCTGCTGAACACTCTG
CGGCACAACCTTGCTCAGGGCAGCACCGGACTTCAGGTGTTTGAACTGGCGCACATATTCGAGGCCGACCAGTCGTCTGA
CACCACCGCGCGTGAATCGGGCAGGCTCGGCCTGCTGGTTTACGGTCAGCGCTATCAGGACGGCTGGCCCCGCCGCGAAG
AAGATGCCGGCTACGAAGACCTTAAGGGTATTGTGGAGCATCTGCTGCGCGTGCTTAATCTCGGTCCGGCTGCCTTTACC
CTGCGCAAGGATCACAGCTGGCTGCTGCCCTGCGTGGAAATACGCGTGGGCAGTGTATGCGCGGGCGTGGCAGGCCGCGT
AAAACCCGATATCGCCGATGCCTATCATGCCCGCAAGGACGTGTGGATGGCGGAAATCGATCTGGACGCGCTGCGTACCC
TTTGCCGCGATGTGGCGGTACAGTTCAGCGCGTTGCCGGTGTTTCCGCCGGTCAAGCGCGACATCACCGTCATGGCGCCT
GCCTCCGTGCCTGTGTCTGCCGTGACAGACCATGTACGCGGCATGAGCCTGAAGCTGTTCAGCGACATCGTGCTGGTTGA
CGTGTTTGAACCGGAAACGCCTGAAGGCGGGACTCCGGAGCGCAACCTGACCTTCCGGCTTACGTTCAGACATGCTGAGC
GTACCCTCAAGGACAAGGAAGTGGACAAGGAACGCGACAAAGTGGCAGAATCGCTTACGGAAGCACTGGGAGTCCGTATC
TAG

Upstream 100 bases:

>100_bases
GGGCGCTGCATGTGCCCCGCTGCGTGGCCTGCCGGATGCGCGGCAAACCAGAATTCAAGCCTGCATGACCGGACTCGCTG
TCCGGCCACGGGAGACGAGG

Downstream 100 bases:

>100_bases
ACGCATATATCCGCCACAGCACTGTCCGGCGTGCGGCCGGACAGTGCTGTGAAGGTTGCGCTTAACAGCAGGGAATCATT
CGTTTCGTCGGCATTCCGTC

Product: phenylalanyl-tRNA synthetase subunit beta

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase beta chain; PheRS

Number of amino acids: Translated: 800; Mature: 800

Protein sequence:

>800_residues
MLLSLNWLREFVPYTGTAQELGDRLTMLGLELEEIIRPFDAIADIVVGHVLECGRHPEADKLSVCRVDVGTEVLDIVCGA
PNVAAGQKVPVAKVGVTMPSGLKIKKAKLRGQPSCGMICSESELELSDESDGIMVLPQDSVPGVRLVDLLQLDDTVLDIS
ITPNRADCLSVLGLAREVALAFDLPLTMPQLELREQGEDAGSDVTIAIADGAQCPVYQGRIIEGISTCPSPLWMRHRLKS
VGVRPISAIVDVTNYILMELGQPLHAFDLDLLEGARIVVETAAEGERFTTLDGQERVLKASDLLIRDGAKAVALAGVMGG
ANTEINDASRRVFLECAVFKPATIRRTARRLGLSSESSYRFERGVDQVLSTFAMNRAAQLMCELSGGVLRPGVCRAEPAP
WQAAQLRFRPARAAALLGISLDDGFCRETLQKLGCTLSGADTPEWTVTAPSHRHDLEREADLIEEVGRVYGMDNIPPVLP
KVSKPLEQGRTDSEYEFWARIKAWGRGLGLNEAVNYSFVGHKDLDFLGLPAGNRISIMNPLTSEQDVLRTELAPGLLNTL
RHNLAQGSTGLQVFELAHIFEADQSSDTTARESGRLGLLVYGQRYQDGWPRREEDAGYEDLKGIVEHLLRVLNLGPAAFT
LRKDHSWLLPCVEIRVGSVCAGVAGRVKPDIADAYHARKDVWMAEIDLDALRTLCRDVAVQFSALPVFPPVKRDITVMAP
ASVPVSAVTDHVRGMSLKLFSDIVLVDVFEPETPEGGTPERNLTFRLTFRHAERTLKDKEVDKERDKVAESLTEALGVRI

Sequences:

>Translated_800_residues
MLLSLNWLREFVPYTGTAQELGDRLTMLGLELEEIIRPFDAIADIVVGHVLECGRHPEADKLSVCRVDVGTEVLDIVCGA
PNVAAGQKVPVAKVGVTMPSGLKIKKAKLRGQPSCGMICSESELELSDESDGIMVLPQDSVPGVRLVDLLQLDDTVLDIS
ITPNRADCLSVLGLAREVALAFDLPLTMPQLELREQGEDAGSDVTIAIADGAQCPVYQGRIIEGISTCPSPLWMRHRLKS
VGVRPISAIVDVTNYILMELGQPLHAFDLDLLEGARIVVETAAEGERFTTLDGQERVLKASDLLIRDGAKAVALAGVMGG
ANTEINDASRRVFLECAVFKPATIRRTARRLGLSSESSYRFERGVDQVLSTFAMNRAAQLMCELSGGVLRPGVCRAEPAP
WQAAQLRFRPARAAALLGISLDDGFCRETLQKLGCTLSGADTPEWTVTAPSHRHDLEREADLIEEVGRVYGMDNIPPVLP
KVSKPLEQGRTDSEYEFWARIKAWGRGLGLNEAVNYSFVGHKDLDFLGLPAGNRISIMNPLTSEQDVLRTELAPGLLNTL
RHNLAQGSTGLQVFELAHIFEADQSSDTTARESGRLGLLVYGQRYQDGWPRREEDAGYEDLKGIVEHLLRVLNLGPAAFT
LRKDHSWLLPCVEIRVGSVCAGVAGRVKPDIADAYHARKDVWMAEIDLDALRTLCRDVAVQFSALPVFPPVKRDITVMAP
ASVPVSAVTDHVRGMSLKLFSDIVLVDVFEPETPEGGTPERNLTFRLTFRHAERTLKDKEVDKERDKVAESLTEALGVRI
>Mature_800_residues
MLLSLNWLREFVPYTGTAQELGDRLTMLGLELEEIIRPFDAIADIVVGHVLECGRHPEADKLSVCRVDVGTEVLDIVCGA
PNVAAGQKVPVAKVGVTMPSGLKIKKAKLRGQPSCGMICSESELELSDESDGIMVLPQDSVPGVRLVDLLQLDDTVLDIS
ITPNRADCLSVLGLAREVALAFDLPLTMPQLELREQGEDAGSDVTIAIADGAQCPVYQGRIIEGISTCPSPLWMRHRLKS
VGVRPISAIVDVTNYILMELGQPLHAFDLDLLEGARIVVETAAEGERFTTLDGQERVLKASDLLIRDGAKAVALAGVMGG
ANTEINDASRRVFLECAVFKPATIRRTARRLGLSSESSYRFERGVDQVLSTFAMNRAAQLMCELSGGVLRPGVCRAEPAP
WQAAQLRFRPARAAALLGISLDDGFCRETLQKLGCTLSGADTPEWTVTAPSHRHDLEREADLIEEVGRVYGMDNIPPVLP
KVSKPLEQGRTDSEYEFWARIKAWGRGLGLNEAVNYSFVGHKDLDFLGLPAGNRISIMNPLTSEQDVLRTELAPGLLNTL
RHNLAQGSTGLQVFELAHIFEADQSSDTTARESGRLGLLVYGQRYQDGWPRREEDAGYEDLKGIVEHLLRVLNLGPAAFT
LRKDHSWLLPCVEIRVGSVCAGVAGRVKPDIADAYHARKDVWMAEIDLDALRTLCRDVAVQFSALPVFPPVKRDITVMAP
ASVPVSAVTDHVRGMSLKLFSDIVLVDVFEPETPEGGTPERNLTFRLTFRHAERTLKDKEVDKERDKVAESLTEALGVRI

Specific function: Unknown

COG id: COG0072

COG function: function code J; Phenylalanyl-tRNA synthetase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 tRNA-binding domain

Homologues:

Organism=Homo sapiens, GI124028525, Length=384, Percent_Identity=22.9166666666667, Blast_Score=74, Evalue=6e-13,
Organism=Escherichia coli, GI1788006, Length=801, Percent_Identity=36.3295880149813, Blast_Score=445, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17533403, Length=607, Percent_Identity=22.8995057660626, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI21355211, Length=394, Percent_Identity=24.3654822335025, Blast_Score=84, Evalue=5e-16,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYFB_DESDG (Q30Y16)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_389125.1
- ProteinModelPortal:   Q30Y16
- STRING:   Q30Y16
- GeneID:   3757656
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_2634
- NMPDR:   fig|207559.3.peg.2851
- eggNOG:   COG0072
- HOGENOM:   HBG399638
- OMA:   ADKLRVC
- ProtClustDB:   PRK00629
- BioCyc:   DDES207559:DDE_2634-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00283
- InterPro:   IPR005146
- InterPro:   IPR005147
- InterPro:   IPR009061
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004532
- InterPro:   IPR020825
- InterPro:   IPR005121
- InterPro:   IPR002547
- Gene3D:   G3DSA:3.50.40.10
- Gene3D:   G3DSA:3.30.56.20
- Gene3D:   G3DSA:3.30.70.380
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00873
- SMART:   SM00874
- SMART:   SM00896
- TIGRFAMs:   TIGR00472

Pfam domain/function: PF03483 B3_4; PF03484 B5; PF03147 FDX-ACB; PF01588 tRNA_bind; SSF56037 B3_4; SSF54991 Fdx_AntiC_bd; SSF50249 Nucleic_acid_OB; SSF46955 Putativ_DNA_bind

EC number: =6.1.1.20

Molecular weight: Translated: 87502; Mature: 87502

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS51483 B5; PS51447 FDX_ACB; PS50886 TRBD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLSLNWLREFVPYTGTAQELGDRLTMLGLELEEIIRPFDAIADIVVGHVLECGRHPEAD
CEEEHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KLSVCRVDVGTEVLDIVCGAPNVAAGQKVPVAKVGVTMPSGLKIKKAKLRGQPSCGMICS
CEEEEEEECCHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCEEEHHHHCCCCCCCEEEC
ESELELSDESDGIMVLPQDSVPGVRLVDLLQLDDTVLDISITPNRADCLSVLGLAREVAL
CCCCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
AFDLPLTMPQLELREQGEDAGSDVTIAIADGAQCPVYQGRIIEGISTCPSPLWMRHRLKS
HCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHHH
VGVRPISAIVDVTNYILMELGQPLHAFDLDLLEGARIVVETAAEGERFTTLDGQERVLKA
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCEEEECCCHHHHHHH
SDLLIRDGAKAVALAGVMGGANTEINDASRRVFLECAVFKPATIRRTARRLGLSSESSYR
HHHHEECCCCCEEHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHH
FERGVDQVLSTFAMNRAAQLMCELSGGVLRPGVCRAEPAPWQAAQLRFRPARAAALLGIS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHEEECCCCEEEEEEEE
LDDGFCRETLQKLGCTLSGADTPEWTVTAPSHRHDLEREADLIEEVGRVYGMDNIPPVLP
CCCHHHHHHHHHHCCEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
KVSKPLEQGRTDSEYEFWARIKAWGRGLGLNEAVNYSFVGHKDLDFLGLPAGNRISIMNP
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHCCEEEECCCCCCEEECCCCCEEEEECC
LTSEQDVLRTELAPGLLNTLRHNLAQGSTGLQVFELAHIFEADQSSDTTARESGRLGLLV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCEEEEE
YGQRYQDGWPRREEDAGYEDLKGIVEHLLRVLNLGPAAFTLRKDHSWLLPCVEIRVGSVC
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHH
AGVAGRVKPDIADAYHARKDVWMAEIDLDALRTLCRDVAVQFSALPVFPPVKRDITVMAP
HCCCCCCCCCHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEC
ASVPVSAVTDHVRGMSLKLFSDIVLVDVFEPETPEGGTPERNLTFRLTFRHAERTLKDKE
CCCCHHHHHHHHCCCCHHHHCCEEEEEEECCCCCCCCCCCCCEEEEEEEHHHHHHHHHHH
VDKERDKVAESLTEALGVRI
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLLSLNWLREFVPYTGTAQELGDRLTMLGLELEEIIRPFDAIADIVVGHVLECGRHPEAD
CEEEHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KLSVCRVDVGTEVLDIVCGAPNVAAGQKVPVAKVGVTMPSGLKIKKAKLRGQPSCGMICS
CEEEEEEECCHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCEEEHHHHCCCCCCCEEEC
ESELELSDESDGIMVLPQDSVPGVRLVDLLQLDDTVLDISITPNRADCLSVLGLAREVAL
CCCCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
AFDLPLTMPQLELREQGEDAGSDVTIAIADGAQCPVYQGRIIEGISTCPSPLWMRHRLKS
HCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHHH
VGVRPISAIVDVTNYILMELGQPLHAFDLDLLEGARIVVETAAEGERFTTLDGQERVLKA
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCEEEECCCHHHHHHH
SDLLIRDGAKAVALAGVMGGANTEINDASRRVFLECAVFKPATIRRTARRLGLSSESSYR
HHHHEECCCCCEEHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHH
FERGVDQVLSTFAMNRAAQLMCELSGGVLRPGVCRAEPAPWQAAQLRFRPARAAALLGIS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHEEECCCCEEEEEEEE
LDDGFCRETLQKLGCTLSGADTPEWTVTAPSHRHDLEREADLIEEVGRVYGMDNIPPVLP
CCCHHHHHHHHHHCCEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
KVSKPLEQGRTDSEYEFWARIKAWGRGLGLNEAVNYSFVGHKDLDFLGLPAGNRISIMNP
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHCCEEEECCCCCCEEECCCCCEEEEECC
LTSEQDVLRTELAPGLLNTLRHNLAQGSTGLQVFELAHIFEADQSSDTTARESGRLGLLV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCEEEEE
YGQRYQDGWPRREEDAGYEDLKGIVEHLLRVLNLGPAAFTLRKDHSWLLPCVEIRVGSVC
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHH
AGVAGRVKPDIADAYHARKDVWMAEIDLDALRTLCRDVAVQFSALPVFPPVKRDITVMAP
HCCCCCCCCCHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEC
ASVPVSAVTDHVRGMSLKLFSDIVLVDVFEPETPEGGTPERNLTFRLTFRHAERTLKDKE
CCCCHHHHHHHHCCCCHHHHCCEEEEEEECCCCCCCCCCCCCEEEEEEEHHHHHHHHHHH
VDKERDKVAESLTEALGVRI
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA