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The map label for this gene is virA [H]

Identifier: 78357413

GI number: 78357413

Start: 2391639

End: 2394026

Strand: Direct

Name: virA [H]

Synonym: Dde_2370

Alternate gene names: 78357413

Gene position: 2391639-2394026 (Clockwise)

Preceding gene: 78357412

Following gene: 78357416

Centisome position: 64.12

GC content: 61.47

Gene sequence:

>2388_bases
ATGCCGGTAAACACCTGTATGCGGCCTGAAACGGCCGGAATTATCCGCCGGTTGCGCCCGCGCGCTTGCCCGGTGACAAA
GGACGCCACCATGCACCATTCGCTCAGCCTGCTTTTTGTCACCTGTTCGGAAGAACTGGCGGACGGCATAGTGCACAGCG
CTTCGGAATGCGGTCTGCACCCCGCCTATTCTCTTGTGGGGTCGGCTCAGGAGCTTTCCCGCGCGCTTGCCGAAGAATCC
TGGGACATCATTCTGGCCGAACCCCATGTGGCGGGCATGCCGTGGCAGCAGATACTTGCGGCCGTGCGCCGTGTGCACGA
AGGGATTCCTTTTGTCCTTGTCATGCCTGCCCCCGACCCGCAGGCCGCGGCGCAGGCCGTCCACGACGGTGCCGATGAAG
TGCTGCTGCCTGCGGACTGGCATACCGGCGCCGCCCTGCAGCGGCTGCGCAGTCAGGCAGTGCTGAGCCGCAGACAAGGT
GCCCGCCGCCGTTCACGCGCAGATGATGAAAAAGAATGGCGCGCGCTGGTCGAAAACACCATGGTCGGCATGTTCCGCTG
CCGCCCCTGGGGCGAGCTGGTACAGGTGAATCCTGCTTTTGCCGCCATATTCGGCTACCGTTCCCCCCAAGAGCTGCTGA
ATGCCCATGCCGGAAAAAAGGGGCCCCATGTTCCGGCCGCAGAAATAAAAGAACTGCTGCCGGCACTGAGGAATGAAGGC
CTGCTGACAGAATACGAGATGCACGCAGCACGGCCCGACGGTTCCGGCGTATGGCTTTCCGTCAATGCCAGAACCATACG
GGGGGCCGCCGGAGAAATTTCGGGCATAGAAGGCACGGTGGAAGACATCGGCAACCGCAAGTCGGTCGAAAACATGATTG
TCCGGGCAAAGCAGGAGTGGGAAAAAACATTCGACAGTGTACCCGACATAATCGTCCTGCTGGACAGCGACCTGCACATA
AGGCGATGCAACATGGCGCTGGGAACGCTGCTGGGCCGCCATCCGCGCGAACTGGTGGGACAGGACAGCCGCAAAACACT
TTTCGACGGCGGCACACACGGCCCTGTGCTTGACTCGCTGCCTGCGCTGAGCCGCGGACAAAGCCATACCGAAGAACTGC
ACCTGCCCGCGCTGGGCGGACATTTTCTGATAACCTTTTCGCCGCTGTTCACCGGCACCGGATCAGATGCGGAACCGGAA
GGCACCGTACTGGTGGCACGCGACATAAGCAGCCGCAAACAGCTGGAAGCACAGTTGCGCCAGGCTCAGAAAATGGAGGC
CATAGGCACGCTGGCAGGCGGAATCGCTCACGATTTCAACAACATCCTCGGCGTGATGATGGGCTATACTGAAATGAGCA
TGGATGAAACCACGGAAGGTTCGGCCATGCAGCGGCGGCTGGACGCCGTACTCTCTGCCGGAAGGCGCGCCCGCGACCTC
ATCCATCAGATACTTACTTTCAGCAGACACGAAGAGCCTTCGCGTCATCCGCTCAACCTTGTTTCCCCCGTCAAGGAAAC
GGTCAAACTGCTGCGGGCTTCGCTGCCGGCCAACATTGCCATCGACCTGCGTACAGACACTGTGCCTCCCGTCAACGCAA
ACCTGAGCCAGATTCAGCAGGTGGTCATGAACCTGTGCGCCAACGCAGCCCACGCCATGCGCGGCCCGGGCGGCAACCTG
CTGCTTGCGCTGGACAGCACCCTGCTTACCGCCGAAGAAGCGCGCCCTCTTTCCGTCCCTGCGGGCACGTATGTCCGCCT
GCGTGTGTCCGACACGGGGCACGGTATCGACCCGCAGATACTGCACAGCATTTTTGACCCGTTTTTCACCACAAAAAAAC
CCGACGAAGGAACGGGCATGGGGCTGGCGCTGGTGCACGGCATCATCACCGCGCACGGCGGTACGGTATCTGTCTCGTCC
GTACCCGGGCAGGGAACAGACTTCACCATACTGCTGCCCGCCACCGACGGACAGAATGTATCGGAACCGGGCGGGTCACT
GCGCCACGCGGGCAGCGGCATTGTGCTGGTGGTGGATGATGAAAAAGCACTGGCAGGCGTCATGGCCGATATGCTGCAAA
GCATGGGATACACCCCGCGCATAGCCGATTCGCCGGCTCAGGCGCTGCACATGGTAAGCCGCGCCCCGCAGGAATTTGCC
CTTGTGCTTACAGACCAGACCATGCCGGACATGACCGGAACAGAGCTGGCGGCACGCCTGCATGCGGTGCGCCCCGACCT
GCCGGTCATTCTGTGCACGGGCTTCAGCGAGGGGCTTACGCGTGAAGCCGCACGCAAGGCCGGAATCAGCGAACTGCTGC
TCAAACCCGTATTACGCGGCGATCTGGCAAAGGCGCTGGCATGTCTTGAATTTGACTGCGGGCTGTGA

Upstream 100 bases:

>100_bases
TGGGCAGTCTGCTGGGACCGGAAATAACGGTGCAGGGCATCGAACGCATGATCAACGAACCATGGGTGGCATGCCGGTGA
GCGTTCCCGTTCTGGCCTGC

Downstream 100 bases:

>100_bases
CCGCAAAAAACCCCTGCCGCAAAAACGGCAGGGGTCAGGAACTGCAGCGCAGCAGAACAATCAGCCCAGCTTGATAACAC
CCAGACCGTTGAGCATGACC

Product: multi-sensor hybrid histidine kinase

Products: NA

Alternate protein names: WHR virA [H]

Number of amino acids: Translated: 795; Mature: 794

Protein sequence:

>795_residues
MPVNTCMRPETAGIIRRLRPRACPVTKDATMHHSLSLLFVTCSEELADGIVHSASECGLHPAYSLVGSAQELSRALAEES
WDIILAEPHVAGMPWQQILAAVRRVHEGIPFVLVMPAPDPQAAAQAVHDGADEVLLPADWHTGAALQRLRSQAVLSRRQG
ARRRSRADDEKEWRALVENTMVGMFRCRPWGELVQVNPAFAAIFGYRSPQELLNAHAGKKGPHVPAAEIKELLPALRNEG
LLTEYEMHAARPDGSGVWLSVNARTIRGAAGEISGIEGTVEDIGNRKSVENMIVRAKQEWEKTFDSVPDIIVLLDSDLHI
RRCNMALGTLLGRHPRELVGQDSRKTLFDGGTHGPVLDSLPALSRGQSHTEELHLPALGGHFLITFSPLFTGTGSDAEPE
GTVLVARDISSRKQLEAQLRQAQKMEAIGTLAGGIAHDFNNILGVMMGYTEMSMDETTEGSAMQRRLDAVLSAGRRARDL
IHQILTFSRHEEPSRHPLNLVSPVKETVKLLRASLPANIAIDLRTDTVPPVNANLSQIQQVVMNLCANAAHAMRGPGGNL
LLALDSTLLTAEEARPLSVPAGTYVRLRVSDTGHGIDPQILHSIFDPFFTTKKPDEGTGMGLALVHGIITAHGGTVSVSS
VPGQGTDFTILLPATDGQNVSEPGGSLRHAGSGIVLVVDDEKALAGVMADMLQSMGYTPRIADSPAQALHMVSRAPQEFA
LVLTDQTMPDMTGTELAARLHAVRPDLPVILCTGFSEGLTREAARKAGISELLLKPVLRGDLAKALACLEFDCGL

Sequences:

>Translated_795_residues
MPVNTCMRPETAGIIRRLRPRACPVTKDATMHHSLSLLFVTCSEELADGIVHSASECGLHPAYSLVGSAQELSRALAEES
WDIILAEPHVAGMPWQQILAAVRRVHEGIPFVLVMPAPDPQAAAQAVHDGADEVLLPADWHTGAALQRLRSQAVLSRRQG
ARRRSRADDEKEWRALVENTMVGMFRCRPWGELVQVNPAFAAIFGYRSPQELLNAHAGKKGPHVPAAEIKELLPALRNEG
LLTEYEMHAARPDGSGVWLSVNARTIRGAAGEISGIEGTVEDIGNRKSVENMIVRAKQEWEKTFDSVPDIIVLLDSDLHI
RRCNMALGTLLGRHPRELVGQDSRKTLFDGGTHGPVLDSLPALSRGQSHTEELHLPALGGHFLITFSPLFTGTGSDAEPE
GTVLVARDISSRKQLEAQLRQAQKMEAIGTLAGGIAHDFNNILGVMMGYTEMSMDETTEGSAMQRRLDAVLSAGRRARDL
IHQILTFSRHEEPSRHPLNLVSPVKETVKLLRASLPANIAIDLRTDTVPPVNANLSQIQQVVMNLCANAAHAMRGPGGNL
LLALDSTLLTAEEARPLSVPAGTYVRLRVSDTGHGIDPQILHSIFDPFFTTKKPDEGTGMGLALVHGIITAHGGTVSVSS
VPGQGTDFTILLPATDGQNVSEPGGSLRHAGSGIVLVVDDEKALAGVMADMLQSMGYTPRIADSPAQALHMVSRAPQEFA
LVLTDQTMPDMTGTELAARLHAVRPDLPVILCTGFSEGLTREAARKAGISELLLKPVLRGDLAKALACLEFDCGL
>Mature_794_residues
PVNTCMRPETAGIIRRLRPRACPVTKDATMHHSLSLLFVTCSEELADGIVHSASECGLHPAYSLVGSAQELSRALAEESW
DIILAEPHVAGMPWQQILAAVRRVHEGIPFVLVMPAPDPQAAAQAVHDGADEVLLPADWHTGAALQRLRSQAVLSRRQGA
RRRSRADDEKEWRALVENTMVGMFRCRPWGELVQVNPAFAAIFGYRSPQELLNAHAGKKGPHVPAAEIKELLPALRNEGL
LTEYEMHAARPDGSGVWLSVNARTIRGAAGEISGIEGTVEDIGNRKSVENMIVRAKQEWEKTFDSVPDIIVLLDSDLHIR
RCNMALGTLLGRHPRELVGQDSRKTLFDGGTHGPVLDSLPALSRGQSHTEELHLPALGGHFLITFSPLFTGTGSDAEPEG
TVLVARDISSRKQLEAQLRQAQKMEAIGTLAGGIAHDFNNILGVMMGYTEMSMDETTEGSAMQRRLDAVLSAGRRARDLI
HQILTFSRHEEPSRHPLNLVSPVKETVKLLRASLPANIAIDLRTDTVPPVNANLSQIQQVVMNLCANAAHAMRGPGGNLL
LALDSTLLTAEEARPLSVPAGTYVRLRVSDTGHGIDPQILHSIFDPFFTTKKPDEGTGMGLALVHGIITAHGGTVSVSSV
PGQGTDFTILLPATDGQNVSEPGGSLRHAGSGIVLVVDDEKALAGVMADMLQSMGYTPRIADSPAQALHMVSRAPQEFAL
VLTDQTMPDMTGTELAARLHAVRPDLPVILCTGFSEGLTREAARKAGISELLLKPVLRGDLAKALACLEFDCGL

Specific function: Activates virG, by phosphorylating it, in the presence of acetosyringone or hydroxysyringone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=356, Percent_Identity=30.0561797752809, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1790436, Length=253, Percent_Identity=30.8300395256917, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI48994928, Length=508, Percent_Identity=23.6220472440945, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1790300, Length=357, Percent_Identity=24.9299719887955, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788713, Length=409, Percent_Identity=23.7163814180929, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1786600, Length=377, Percent_Identity=24.4031830238727, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI87081816, Length=383, Percent_Identity=25.5874673629243, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI145693157, Length=280, Percent_Identity=25, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1786912, Length=255, Percent_Identity=24.7058823529412, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 85634; Mature: 85503

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVNTCMRPETAGIIRRLRPRACPVTKDATMHHSLSLLFVTCSEELADGIVHSASECGLH
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHCCEEEEEEECCHHHHHHHHHHHHHCCCC
PAYSLVGSAQELSRALAEESWDIILAEPHVAGMPWQQILAAVRRVHEGIPFVLVMPAPDP
HHHHHHCCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCH
QAAAQAVHDGADEVLLPADWHTGAALQRLRSQAVLSRRQGARRRSRADDEKEWRALVENT
HHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
MVGMFRCRPWGELVQVNPAFAAIFGYRSPQELLNAHAGKKGPHVPAAEIKELLPALRNEG
HHHHHEECCCHHHEEECHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
LLTEYEMHAARPDGSGVWLSVNARTIRGAAGEISGIEGTVEDIGNRKSVENMIVRAKQEW
CCEEHHHHCCCCCCCEEEEEECCEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHH
EKTFDSVPDIIVLLDSDLHIRRCNMALGTLLGRHPRELVGQDSRKTLFDGGTHGPVLDSL
HHHHHCCCCEEEEECCCCCEEHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHCC
PALSRGQSHTEELHLPALGGHFLITFSPLFTGTGSDAEPEGTVLVARDISSRKQLEAQLR
CHHHCCCCCHHHEECCCCCCEEEEEEEHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHH
QAQKMEAIGTLAGGIAHDFNNILGVMMGYTEMSMDETTEGSAMQRRLDAVLSAGRRARDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHH
IHQILTFSRHEEPSRHPLNLVSPVKETVKLLRASLPANIAIDLRTDTVPPVNANLSQIQQ
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHH
VVMNLCANAAHAMRGPGGNLLLALDSTLLTAEEARPLSVPAGTYVRLRVSDTGHGIDPQI
HHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHH
LHSIFDPFFTTKKPDEGTGMGLALVHGIITAHGGTVSVSSVPGQGTDFTILLPATDGQNV
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCCCCC
SEPGGSLRHAGSGIVLVVDDEKALAGVMADMLQSMGYTPRIADSPAQALHMVSRAPQEFA
CCCCCCHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEE
LVLTDQTMPDMTGTELAARLHAVRPDLPVILCTGFSEGLTREAARKAGISELLLKPVLRG
EEEECCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHH
DLAKALACLEFDCGL
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
PVNTCMRPETAGIIRRLRPRACPVTKDATMHHSLSLLFVTCSEELADGIVHSASECGLH
CCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHCCEEEEEEECCHHHHHHHHHHHHHCCCC
PAYSLVGSAQELSRALAEESWDIILAEPHVAGMPWQQILAAVRRVHEGIPFVLVMPAPDP
HHHHHHCCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCH
QAAAQAVHDGADEVLLPADWHTGAALQRLRSQAVLSRRQGARRRSRADDEKEWRALVENT
HHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
MVGMFRCRPWGELVQVNPAFAAIFGYRSPQELLNAHAGKKGPHVPAAEIKELLPALRNEG
HHHHHEECCCHHHEEECHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
LLTEYEMHAARPDGSGVWLSVNARTIRGAAGEISGIEGTVEDIGNRKSVENMIVRAKQEW
CCEEHHHHCCCCCCCEEEEEECCEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHH
EKTFDSVPDIIVLLDSDLHIRRCNMALGTLLGRHPRELVGQDSRKTLFDGGTHGPVLDSL
HHHHHCCCCEEEEECCCCCEEHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCHHHCC
PALSRGQSHTEELHLPALGGHFLITFSPLFTGTGSDAEPEGTVLVARDISSRKQLEAQLR
CHHHCCCCCHHHEECCCCCCEEEEEEEHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHH
QAQKMEAIGTLAGGIAHDFNNILGVMMGYTEMSMDETTEGSAMQRRLDAVLSAGRRARDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHH
IHQILTFSRHEEPSRHPLNLVSPVKETVKLLRASLPANIAIDLRTDTVPPVNANLSQIQQ
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHH
VVMNLCANAAHAMRGPGGNLLLALDSTLLTAEEARPLSVPAGTYVRLRVSDTGHGIDPQI
HHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHH
LHSIFDPFFTTKKPDEGTGMGLALVHGIITAHGGTVSVSSVPGQGTDFTILLPATDGQNV
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCCCCC
SEPGGSLRHAGSGIVLVVDDEKALAGVMADMLQSMGYTPRIADSPAQALHMVSRAPQEFA
CCCCCCHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEE
LVLTDQTMPDMTGTELAARLHAVRPDLPVILCTGFSEGLTREAARKAGISELLLKPVLRG
EEEECCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHH
DLAKALACLEFDCGL
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2796735; 2194232; 11743193; 11743194 [H]