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The map label for this gene is ilvH

Identifier: 78357210

GI number: 78357210

Start: 2210264

End: 2210755

Strand: Reverse

Name: ilvH

Synonym: Dde_2167

Alternate gene names: 78357210

Gene position: 2210755-2210264 (Counterclockwise)

Preceding gene: 78357211

Following gene: 78357209

Centisome position: 59.27

GC content: 50.81

Gene sequence:

>492_bases
ATGCGTCATGTACTTTCCGTTCTGGTGGAAAACGAACCGGGCGTTCTTTCCCGGGTGGCCGGGCTGTTCAGCGGCAGGGG
GTTCAACATTGAATCGCTTAACGTTGCCCCGACTCTTGAAGCCGGTGTATCTTTGATGACCATCAGCACCAGCGGTGATG
ATCAGATTATCGAGCAGATTGTTAAACAGCTGCGAAAGCTGGTGACAGTTATAAAAGTTGTTGACTTCGAAGATATAGCC
GCCGTAGAGCGGGAGATGGTTATTTTAAAGGTTAACGCCGAGGAAACGCGCAGGGCGGAAGTTCTGCGCATTGCCGATAT
TTTCCGTTGCAAGGTGGTCGATGTGAGTTTGCATGATCTGACGCTGGAAGCGACCGGCGATCATGGTAAAATTCAGGCAG
TGATTCAGCTGCTAACCAGATTCGGCATCAAGGAGATAGCCAGAACTGGTACCGTGGCTATGAAGCGCTCCATGCAACCG
GAACAGGTTTAA

Upstream 100 bases:

>100_bases
GGCTATTGTTGATGTGCGCGTGGAGCGCGAGGAAAATGTCTATCCCATGGTTCCGGCCGGTGCGGCGCTGGACGAGATGC
TGCTTGTGTAGGAGACTTCC

Downstream 100 bases:

>100_bases
CTGCATTTTTGCGGCAACCCACCTGACGGGCGCTTGAGCCTCTCAGGTGGGTTTTTTTATAGGTAACCACTAACCTTTGG
GAAGCTGTACAAGCTACAGC

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MRHVLSVLVENEPGVLSRVAGLFSGRGFNIESLNVAPTLEAGVSLMTISTSGDDQIIEQIVKQLRKLVTVIKVVDFEDIA
AVEREMVILKVNAEETRRAEVLRIADIFRCKVVDVSLHDLTLEATGDHGKIQAVIQLLTRFGIKEIARTGTVAMKRSMQP
EQV

Sequences:

>Translated_163_residues
MRHVLSVLVENEPGVLSRVAGLFSGRGFNIESLNVAPTLEAGVSLMTISTSGDDQIIEQIVKQLRKLVTVIKVVDFEDIA
AVEREMVILKVNAEETRRAEVLRIADIFRCKVVDVSLHDLTLEATGDHGKIQAVIQLLTRFGIKEIARTGTVAMKRSMQP
EQV
>Mature_163_residues
MRHVLSVLVENEPGVLSRVAGLFSGRGFNIESLNVAPTLEAGVSLMTISTSGDDQIIEQIVKQLRKLVTVIKVVDFEDIA
AVEREMVILKVNAEETRRAEVLRIADIFRCKVVDVSLHDLTLEATGDHGKIQAVIQLLTRFGIKEIARTGTVAMKRSMQP
EQV

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=157, Percent_Identity=47.7707006369427, Blast_Score=135, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319837, Length=205, Percent_Identity=33.1707317073171, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 17991; Mature: 17991

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHVLSVLVENEPGVLSRVAGLFSGRGFNIESLNVAPTLEAGVSLMTISTSGDDQIIEQI
CHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEECCCCCHHHCCEEEEEEECCCCHHHHHHH
VKQLRKLVTVIKVVDFEDIAAVEREMVILKVNAEETRRAEVLRIADIFRCKVVDVSLHDL
HHHHHHHHHHHHHHCHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHEEEEEEEEEEEE
TLEATGDHGKIQAVIQLLTRFGIKEIARTGTVAMKRSMQPEQV
EEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRHVLSVLVENEPGVLSRVAGLFSGRGFNIESLNVAPTLEAGVSLMTISTSGDDQIIEQI
CHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEECCCCCHHHCCEEEEEEECCCCHHHHHHH
VKQLRKLVTVIKVVDFEDIAAVEREMVILKVNAEETRRAEVLRIADIFRCKVVDVSLHDL
HHHHHHHHHHHHHHCHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHEEEEEEEEEEEE
TLEATGDHGKIQAVIQLLTRFGIKEIARTGTVAMKRSMQPEQV
EEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]