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The map label for this gene is yisQ [H]

Identifier: 78357205

GI number: 78357205

Start: 2206737

End: 2208098

Strand: Direct

Name: yisQ [H]

Synonym: Dde_2162

Alternate gene names: 78357205

Gene position: 2206737-2208098 (Clockwise)

Preceding gene: 78357203

Following gene: 78357206

Centisome position: 59.16

GC content: 59.25

Gene sequence:

>1362_bases
ATGTCCCAGACCCGATCCACCGCAACACAGCAACACCCGTTCAGAACAAAACCAGCCAGAACATTTCTGTCACTGGCTGT
GCCGGTGCTGTTCTCGCTGGTGGCAGAACCGCTGACAGGTCTTGCAGACACGGCCTTTGTAGCCAGACTGGGCGAAGCGC
CGCTGGCAGCACTGGGCGTGGGCACCATGACCCTCTCGGCCATTTTCTGGGCATTCAATTTTCTGAGCATAGGAACACAG
ACAGAAGTGGCACAGGCTCTTGGCGGCGGTAACAGAGAAAAAGCGGCAGACACATGCGGAGCCGCCCTGCTCCTTTCATG
CTCACTCGGCGTGGTCACGGCTCTGGCGGCGCTCCCTTTTCTGCATCCGATCGTAACTTTCATGGGGGCCGACGAAACCA
TGGCTCCGCTGGCAGCAGAATACATCCGCCTGCGCCTTGTGGGGGCTCCCGCCCTGCTTGTGACTCTGGCCGGCATCGGA
GCGCTGCGGGGGCTGCAGGACATGCGCACACCGTTCTGGGTAGCCTGCATTGTCAATATAATGAACATTCTGCTGGACTG
GCTGCTTATATTCGGTATCGGGCCTTTTCTCGCGCTGGGCGTTTCCGGTGCGGCACTGGCCACATCGTGCAGCCAGTGGG
CCGGCGCGGCATGGACGCTGGCCGTGGTGTGGAAAAGGCTGCGTCCTTCATGGCACATCCAGCTGCACGACATAAAAAAG
CTGTTCACCATCGGCGGCGATCTTTTTGTACGCTCAGGAATGGTCATTCTGTTTCTGCTGCTGGGCACCAGAGCAGCCAC
CGCGGCAGGTACTGACGCCGGAGCGGCGCATCAGGCCATAAGACAGTTTTTCATCTTCACGGCATTGTTTCTGGATACCT
TTGCCATTACCGGACAAAGCCTCATCGGTCTTTTTTTCGGCCAGCGCGATATTGCCGCATCGCGTCTGGTCGCCTCTTTT
GTCTGCCGCTGGAGCCTGTGGACAGGTTGTCTGCTTTCTGTAGTGATGCTTGCAGGACAAAAAGGCATCGCATGGCTGCT
GGTGCCCGCATCTGTGCTGGATACATTTATTCCCGCATGGGTGGTGGCGGCGCTTATCCAGCCGGTGAACGCACTCTCTT
TTGCCACCGACGGCATCCACTGGGGCACAGGTGATTTCCGCTTCATCCGCAACGCCATGGTTGCGGCTTCCACCACGGCC
ATTGCCGCTCTTATCTGCATCACCTACCTGCAACCTGCCGCCATGCTCAACTGGGTATGGGGCATTACCGGACTGTGGAC
TACAGTCCGTGCCGGATTCGGCCTGTACCGCATCTGGCCCGGATCCCCGTCAGCCCCGCTGGGGCGCAGCAGCCCGCTGT
AG

Upstream 100 bases:

>100_bases
CTGTCTTGTCAATGCGCGCCGGAGTGCTTTTGTTCCCCGGCAAAGTACGCTATGAGTTCCTAACCACGTGCGCAGATTGT
GCATTCATACAGGAGCCGCC

Downstream 100 bases:

>100_bases
CGGTGTCCTGTACCCCGCGTACCCCGCCTGCTCATTCCTGTGCACACTGCGATTCTCTTTTACGTCTACCGGATATCACT
ATGAGCATACTCCAGATAAA

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MSQTRSTATQQHPFRTKPARTFLSLAVPVLFSLVAEPLTGLADTAFVARLGEAPLAALGVGTMTLSAIFWAFNFLSIGTQ
TEVAQALGGGNREKAADTCGAALLLSCSLGVVTALAALPFLHPIVTFMGADETMAPLAAEYIRLRLVGAPALLVTLAGIG
ALRGLQDMRTPFWVACIVNIMNILLDWLLIFGIGPFLALGVSGAALATSCSQWAGAAWTLAVVWKRLRPSWHIQLHDIKK
LFTIGGDLFVRSGMVILFLLLGTRAATAAGTDAGAAHQAIRQFFIFTALFLDTFAITGQSLIGLFFGQRDIAASRLVASF
VCRWSLWTGCLLSVVMLAGQKGIAWLLVPASVLDTFIPAWVVAALIQPVNALSFATDGIHWGTGDFRFIRNAMVAASTTA
IAALICITYLQPAAMLNWVWGITGLWTTVRAGFGLYRIWPGSPSAPLGRSSPL

Sequences:

>Translated_453_residues
MSQTRSTATQQHPFRTKPARTFLSLAVPVLFSLVAEPLTGLADTAFVARLGEAPLAALGVGTMTLSAIFWAFNFLSIGTQ
TEVAQALGGGNREKAADTCGAALLLSCSLGVVTALAALPFLHPIVTFMGADETMAPLAAEYIRLRLVGAPALLVTLAGIG
ALRGLQDMRTPFWVACIVNIMNILLDWLLIFGIGPFLALGVSGAALATSCSQWAGAAWTLAVVWKRLRPSWHIQLHDIKK
LFTIGGDLFVRSGMVILFLLLGTRAATAAGTDAGAAHQAIRQFFIFTALFLDTFAITGQSLIGLFFGQRDIAASRLVASF
VCRWSLWTGCLLSVVMLAGQKGIAWLLVPASVLDTFIPAWVVAALIQPVNALSFATDGIHWGTGDFRFIRNAMVAASTTA
IAALICITYLQPAAMLNWVWGITGLWTTVRAGFGLYRIWPGSPSAPLGRSSPL
>Mature_452_residues
SQTRSTATQQHPFRTKPARTFLSLAVPVLFSLVAEPLTGLADTAFVARLGEAPLAALGVGTMTLSAIFWAFNFLSIGTQT
EVAQALGGGNREKAADTCGAALLLSCSLGVVTALAALPFLHPIVTFMGADETMAPLAAEYIRLRLVGAPALLVTLAGIGA
LRGLQDMRTPFWVACIVNIMNILLDWLLIFGIGPFLALGVSGAALATSCSQWAGAAWTLAVVWKRLRPSWHIQLHDIKKL
FTIGGDLFVRSGMVILFLLLGTRAATAAGTDAGAAHQAIRQFFIFTALFLDTFAITGQSLIGLFFGQRDIAASRLVASFV
CRWSLWTGCLLSVVMLAGQKGIAWLLVPASVLDTFIPAWVVAALIQPVNALSFATDGIHWGTGDFRFIRNAMVAASTTAI
AALICITYLQPAAMLNWVWGITGLWTTVRAGFGLYRIWPGSPSAPLGRSSPL

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=397, Percent_Identity=29.4710327455919, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI226510954, Length=233, Percent_Identity=28.755364806867, Blast_Score=86, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48162; Mature: 48031

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTRSTATQQHPFRTKPARTFLSLAVPVLFSLVAEPLTGLADTAFVARLGEAPLAALGV
CCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
GTMTLSAIFWAFNFLSIGTQTEVAQALGGGNREKAADTCGAALLLSCSLGVVTALAALPF
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHPIVTFMGADETMAPLAAEYIRLRLVGAPALLVTLAGIGALRGLQDMRTPFWVACIVNI
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
MNILLDWLLIFGIGPFLALGVSGAALATSCSQWAGAAWTLAVVWKRLRPSWHIQLHDIKK
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEHHHHHH
LFTIGGDLFVRSGMVILFLLLGTRAATAAGTDAGAAHQAIRQFFIFTALFLDTFAITGQS
HHHHCHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIGLFFGQRDIAASRLVASFVCRWSLWTGCLLSVVMLAGQKGIAWLLVPASVLDTFIPAW
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHH
VVAALIQPVNALSFATDGIHWGTGDFRFIRNAMVAASTTAIAALICITYLQPAAMLNWVW
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GITGLWTTVRAGFGLYRIWPGSPSAPLGRSSPL
HHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
SQTRSTATQQHPFRTKPARTFLSLAVPVLFSLVAEPLTGLADTAFVARLGEAPLAALGV
CCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
GTMTLSAIFWAFNFLSIGTQTEVAQALGGGNREKAADTCGAALLLSCSLGVVTALAALPF
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHPIVTFMGADETMAPLAAEYIRLRLVGAPALLVTLAGIGALRGLQDMRTPFWVACIVNI
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
MNILLDWLLIFGIGPFLALGVSGAALATSCSQWAGAAWTLAVVWKRLRPSWHIQLHDIKK
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEHHHHHH
LFTIGGDLFVRSGMVILFLLLGTRAATAAGTDAGAAHQAIRQFFIFTALFLDTFAITGQS
HHHHCHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIGLFFGQRDIAASRLVASFVCRWSLWTGCLLSVVMLAGQKGIAWLLVPASVLDTFIPAW
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHH
VVAALIQPVNALSFATDGIHWGTGDFRFIRNAMVAASTTAIAALICITYLQPAAMLNWVW
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GITGLWTTVRAGFGLYRIWPGSPSAPLGRSSPL
HHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]