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The map label for this gene is hupD [H]

Identifier: 78357179

GI number: 78357179

Start: 2183837

End: 2184307

Strand: Direct

Name: hupD [H]

Synonym: Dde_2136

Alternate gene names: 78357179

Gene position: 2183837-2184307 (Clockwise)

Preceding gene: 78357178

Following gene: 78357180

Centisome position: 58.54

GC content: 52.65

Gene sequence:

>471_bases
ATGCCCCGACTGCTGGTACTGGGAATCGGCAACAACCTGCTTACTGACGACGGTGTCGGTGTTTTTGCGGCTGAAGCACT
TCTGAAAGAAAGCTGGCCCGAGAATGTCACCATCATGGACGGCGGCACTTTTACGCAGGATATTTTCTACCTGTTCGAAG
GATACGACAGGCTGCTGGTGCTTGATGTGATCCATGCCGGCCATCCCCCCGGAACAATTTACCGGCTCACCGAAGACGAC
CTGATTCAGAAGGACAGCCAGCGGCTTTCCATACATGACGTTGACCTCATAGATTCGCTGAAAATGGCGGAACTGCGAGG
CAAACGCCCGCGCCTGCAGGTTGTCGGCATGGAACCCAAAGACATCACCACATGGAATATCGGACTTTCGGAACCATGCA
GAAACAGTTTTGAAAATTTTCTTGACGCCGCAAGGCAGGACATACGCGCCATAATTGAAGAGATGGGCTGA

Upstream 100 bases:

>100_bases
TTCGGGCCCCTTTTCTGTTACCCCGCTGCGGCGTCCGCAGGCTTGCCATGTGGCCGCCGGAAAAGCTACAACCGGCAAAA
CACAAGACGAAGGAGCACAC

Downstream 100 bases:

>100_bases
TACGCCCGCAACCTGATTTTACAGGCTGTTTTCCCAGAGAAAACAGCCTTTTTCTTTTACCGACTGGTCACCCGCACAAT
GTAGCTAGCCATCGGTAACA

Product: peptidase M52, hydrogen uptake protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MPRLLVLGIGNNLLTDDGVGVFAAEALLKESWPENVTIMDGGTFTQDIFYLFEGYDRLLVLDVIHAGHPPGTIYRLTEDD
LIQKDSQRLSIHDVDLIDSLKMAELRGKRPRLQVVGMEPKDITTWNIGLSEPCRNSFENFLDAARQDIRAIIEEMG

Sequences:

>Translated_156_residues
MPRLLVLGIGNNLLTDDGVGVFAAEALLKESWPENVTIMDGGTFTQDIFYLFEGYDRLLVLDVIHAGHPPGTIYRLTEDD
LIQKDSQRLSIHDVDLIDSLKMAELRGKRPRLQVVGMEPKDITTWNIGLSEPCRNSFENFLDAARQDIRAIIEEMG
>Mature_155_residues
PRLLVLGIGNNLLTDDGVGVFAAEALLKESWPENVTIMDGGTFTQDIFYLFEGYDRLLVLDVIHAGHPPGTIYRLTEDDL
IQKDSQRLSIHDVDLIDSLKMAELRGKRPRLQVVGMEPKDITTWNIGLSEPCRNSFENFLDAARQDIRAIIEEMG

Specific function: Not known. Could be involved in the processing of hydrogenase [H]

COG id: COG0680

COG function: function code C; Ni,Fe-hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A31 family [H]

Homologues:

Organism=Escherichia coli, GI1787209, Length=138, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1789367, Length=157, Percent_Identity=31.2101910828025, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004419
- InterPro:   IPR000671 [H]

Pfam domain/function: PF01750 HycI [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 17556; Mature: 17425

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLLVLGIGNNLLTDDGVGVFAAEALLKESWPENVTIMDGGTFTQDIFYLFEGYDRLLV
CCCEEEEECCCCEECCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCCEEE
LDVIHAGHPPGTIYRLTEDDLIQKDSQRLSIHDVDLIDSLKMAELRGKRPRLQVVGMEPK
EEHHHCCCCCCEEEEECCHHHHHCCCCEEEEECHHHHHHHHHHHHCCCCCCEEEEECCCC
DITTWNIGLSEPCRNSFENFLDAARQDIRAIIEEMG
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PRLLVLGIGNNLLTDDGVGVFAAEALLKESWPENVTIMDGGTFTQDIFYLFEGYDRLLV
CCEEEEECCCCEECCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCCEEE
LDVIHAGHPPGTIYRLTEDDLIQKDSQRLSIHDVDLIDSLKMAELRGKRPRLQVVGMEPK
EEHHHCCCCCCEEEEECCHHHHHCCCCEEEEECHHHHHHHHHHHHCCCCCCEEEEECCCC
DITTWNIGLSEPCRNSFENFLDAARQDIRAIIEEMG
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Ni [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1597428 [H]