Click here to switch to the map view.

The map label for this gene is dapB

Identifier: 78357135

GI number: 78357135

Start: 2140214

End: 2140993

Strand: Reverse

Name: dapB

Synonym: Dde_2092

Alternate gene names: 78357135

Gene position: 2140993-2140214 (Counterclockwise)

Preceding gene: 78357136

Following gene: 78357134

Centisome position: 57.4

GC content: 58.72

Gene sequence:

>780_bases
ATGAGTGTTTCCGTTATTGTGATGGGTGCCGGCGGGCGTATGGGCACAACCATTACCGGTATGGTGCGTGCTGACGGAGA
ATGCCGTCTTGCCGGTGTGGTCGAACGCGAAGGCCGCCGTGAAGGACTGGAACATCTGGGCTGTCAGGTGGCCGGAACGC
TGGAGGAACTGCTGCCCGGAATGCCCGATGCCGTGGTCATCGATTTTACCGCACCGGAAGCCAGCGTGCATAACGCGCGG
GCGTGTGCGCGGCACGGCAGCGGGCTGGTCATCGGCACAACGGGTTTCACCGAAGAGCAGAAAGCCGAACTTGCGGATTG
CGCATTGCAGACTCCCGTGTTCTGGGCTCCCAACATGAGTGTGGGGGTTAATGTGCTGCTGAAAATTCTGCCCCAGCTGG
TAACGTTGCTGGGCGAACAGTATGATCTGGAAATGGTGGAACTGCACCACAACAAAAAGAAAGACTCTCCCAGCGGGACG
GCACTGCGCCTTGCCGAATGTCTGGCGGAAGCCCGGAAATGGGATCTGGACACGGTGGCCAATTATCACCGTGAAGGTAT
CATCGGAGAACGTCCGCACGAGGAAATAGGCATTCAGACCATTCGCGGCGGAGATGTGGTCGGCGTACACACGGTCTATG
CTCTGGGTCCCGGCGAGCGCATCGAAGTGACCCATCAGGCCCATTCGCGTGAAACCTTTGCAGCAGGGGCTATCCGTGCC
GCAAAGTGGCTGGCGCAGAACAGACCCGGTAAACTGTATACCATGTCGGACATGCTGTAG

Upstream 100 bases:

>100_bases
AGGCAGGCATCAGAGTCTGAAGAAATTTCCGGACAGGCTGCAGATGACTATGAAAACAGTCTGCTGCGCGTGCAGTAGGC
GCCAGAGCGAGGAGGACGTC

Downstream 100 bases:

>100_bases
ATGCGTATCGCTCTGTTACAACTGAACCCCGTGGTGGGTGATCTTGCAGCCAATGCGTCTGCCATTGCCGGTGCGGTGCG
AAGCGCCAGTGCAGGGGGTG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSVSVIVMGAGGRMGTTITGMVRADGECRLAGVVEREGRREGLEHLGCQVAGTLEELLPGMPDAVVIDFTAPEASVHNAR
ACARHGSGLVIGTTGFTEEQKAELADCALQTPVFWAPNMSVGVNVLLKILPQLVTLLGEQYDLEMVELHHNKKKDSPSGT
ALRLAECLAEARKWDLDTVANYHREGIIGERPHEEIGIQTIRGGDVVGVHTVYALGPGERIEVTHQAHSRETFAAGAIRA
AKWLAQNRPGKLYTMSDML

Sequences:

>Translated_259_residues
MSVSVIVMGAGGRMGTTITGMVRADGECRLAGVVEREGRREGLEHLGCQVAGTLEELLPGMPDAVVIDFTAPEASVHNAR
ACARHGSGLVIGTTGFTEEQKAELADCALQTPVFWAPNMSVGVNVLLKILPQLVTLLGEQYDLEMVELHHNKKKDSPSGT
ALRLAECLAEARKWDLDTVANYHREGIIGERPHEEIGIQTIRGGDVVGVHTVYALGPGERIEVTHQAHSRETFAAGAIRA
AKWLAQNRPGKLYTMSDML
>Mature_258_residues
SVSVIVMGAGGRMGTTITGMVRADGECRLAGVVEREGRREGLEHLGCQVAGTLEELLPGMPDAVVIDFTAPEASVHNARA
CARHGSGLVIGTTGFTEEQKAELADCALQTPVFWAPNMSVGVNVLLKILPQLVTLLGEQYDLEMVELHHNKKKDSPSGTA
LRLAECLAEARKWDLDTVANYHREGIIGERPHEEIGIQTIRGGDVVGVHTVYALGPGERIEVTHQAHSRETFAAGAIRAA
KWLAQNRPGKLYTMSDML

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=265, Percent_Identity=42.6415094339623, Blast_Score=188, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_DESDG (Q30ZK7)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_388584.1
- ProteinModelPortal:   Q30ZK7
- SMR:   Q30ZK7
- STRING:   Q30ZK7
- GeneID:   3757100
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_2092
- NMPDR:   fig|207559.3.peg.2240
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- BioCyc:   DDES207559:DDE_2092-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27911; Mature: 27780

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSVIVMGAGGRMGTTITGMVRADGECRLAGVVEREGRREGLEHLGCQVAGTLEELLPG
CCEEEEEEECCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHHHHHCCHHHCCHHHHCCC
MPDAVVIDFTAPEASVHNARACARHGSGLVIGTTGFTEEQKAELADCALQTPVFWAPNMS
CCCEEEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCC
VGVNVLLKILPQLVTLLGEQYDLEMVELHHNKKKDSPSGTALRLAECLAEARKWDLDTVA
HHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
NYHREGIIGERPHEEIGIQTIRGGDVVGVHTVYALGPGERIEVTHQAHSRETFAAGAIRA
HHHHCCCCCCCCCHHHCEEEECCCCEEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHH
AKWLAQNRPGKLYTMSDML
HHHHHCCCCCCEEECCCCC
>Mature Secondary Structure 
SVSVIVMGAGGRMGTTITGMVRADGECRLAGVVEREGRREGLEHLGCQVAGTLEELLPG
CEEEEEEECCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHHHHHCCHHHCCHHHHCCC
MPDAVVIDFTAPEASVHNARACARHGSGLVIGTTGFTEEQKAELADCALQTPVFWAPNMS
CCCEEEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCC
VGVNVLLKILPQLVTLLGEQYDLEMVELHHNKKKDSPSGTALRLAECLAEARKWDLDTVA
HHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
NYHREGIIGERPHEEIGIQTIRGGDVVGVHTVYALGPGERIEVTHQAHSRETFAAGAIRA
HHHHCCCCCCCCCHHHCEEEECCCCEEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHH
AKWLAQNRPGKLYTMSDML
HHHHHCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA