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The map label for this gene is acpS

Identifier: 78357087

GI number: 78357087

Start: 2086992

End: 2087363

Strand: Direct

Name: acpS

Synonym: Dde_2044

Alternate gene names: 78357087

Gene position: 2086992-2087363 (Clockwise)

Preceding gene: 304570586

Following gene: 78357088

Centisome position: 55.95

GC content: 57.53

Gene sequence:

>372_bases
ATGATTTTAGGAACAGGACTGGACCTGACCGAACTCGGACGCATACGCGCCGCCCTTGAAAGGCAGCCTGAAAGGTTTCC
GCGCCGCATTCTGCATGATTCTGAACTTGCGGCCATGCCACGTCTGTCCGTCGCGTGGCTGGCCGCACGTTTTGCCGCCA
AGGAAGCCGCGGCAAAGGCACTGGGAACAGGATTCACCGGCGGTGTGGCGTTCAGGGACATCGAAGTGTATAAGGAACTG
TCGGGAAAGCCATGCCTGCGCTTTCACGGCGCCGCGTTTGAGCATGCACAAAAAATGGGTGTGAAAAAAATCCACCTTTC
ACTGACCCACGGCAGAGACACCGCTGCCGCCGTTGTCATACTCGAAGGCTGA

Upstream 100 bases:

>100_bases
TGTTTCCAGAGCTGTGCTGACAGGCATGGAAAAAGCCGTGGCACAGATGGCGGCCATCATAGCCACGTTCAGCGAATAGC
CCTTCACCGCGGAAACAGGC

Downstream 100 bases:

>100_bases
CAAAGGGGCCCCGCGGATCTGCAACAAGAGGTGTGTTTATGTTTCTCCCCCTGCCCACACCACAGGAAATGAACCGGTGG
GATCAGGCTGCCGTTGACGA

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MILGTGLDLTELGRIRAALERQPERFPRRILHDSELAAMPRLSVAWLAARFAAKEAAAKALGTGFTGGVAFRDIEVYKEL
SGKPCLRFHGAAFEHAQKMGVKKIHLSLTHGRDTAAAVVILEG

Sequences:

>Translated_123_residues
MILGTGLDLTELGRIRAALERQPERFPRRILHDSELAAMPRLSVAWLAARFAAKEAAAKALGTGFTGGVAFRDIEVYKEL
SGKPCLRFHGAAFEHAQKMGVKKIHLSLTHGRDTAAAVVILEG
>Mature_123_residues
MILGTGLDLTELGRIRAALERQPERFPRRILHDSELAAMPRLSVAWLAARFAAKEAAAKALGTGFTGGVAFRDIEVYKEL
SGKPCLRFHGAAFEHAQKMGVKKIHLSLTHGRDTAAAVVILEG

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=123, Percent_Identity=46.3414634146341, Blast_Score=102, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_DESDG (Q30ZQ5)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_388536.1
- ProteinModelPortal:   Q30ZQ5
- SMR:   Q30ZQ5
- STRING:   Q30ZQ5
- GeneID:   3757052
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_2044
- NMPDR:   fig|207559.3.peg.2327
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   VHVSITH
- ProtClustDB:   PRK14657
- BioCyc:   DDES207559:DDE_2044-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13348; Mature: 13348

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILGTGLDLTELGRIRAALERQPERFPRRILHDSELAAMPRLSVAWLAARFAAKEAAAKA
CEECCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHH
LGTGFTGGVAFRDIEVYKELSGKPCLRFHGAAFEHAQKMGVKKIHLSLTHGRDTAAAVVI
HCCCCCCCEEHHHHHHHHHCCCCCCEEECCHHHHHHHHCCCEEEEEEEECCCCCEEEEEE
LEG
EEC
>Mature Secondary Structure
MILGTGLDLTELGRIRAALERQPERFPRRILHDSELAAMPRLSVAWLAARFAAKEAAAKA
CEECCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHH
LGTGFTGGVAFRDIEVYKELSGKPCLRFHGAAFEHAQKMGVKKIHLSLTHGRDTAAAVVI
HCCCCCCCEEHHHHHHHHHCCCCCCEEECCHHHHHHHHCCCEEEEEEEECCCCCEEEEEE
LEG
EEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA