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The map label for this gene is pyrR [H]

Identifier: 78357059

GI number: 78357059

Start: 2058668

End: 2059201

Strand: Reverse

Name: pyrR [H]

Synonym: Dde_2016

Alternate gene names: 78357059

Gene position: 2059201-2058668 (Counterclockwise)

Preceding gene: 78357064

Following gene: 78357055

Centisome position: 55.2

GC content: 58.05

Gene sequence:

>534_bases
ATGCAGAAAAAGTGCATTCTTTCGGCACAGGACATAGCCAGAACGCTTGAGCGGCTGGCCTGTGAGGTACTTGAACGCCA
CGGAGACGCGGACAATCTTGCTCTGGTGGGCATCCAGCGCCGCGGGGTGGACATAGCGGGCAGACTGCGTGGTCTTTTGT
CCGCCCGGCTGGGCAGAGAGGTTGCTCTGGGCAGTCTGGATATCAATCTTTACCGGGATGACTGGACCAGTCTGGACACC
CAGCCCATGATCAACCGCACGGAGCTGCCTTTTGCCGTGGATGACGCCCGGATAGTGCTGGTGGACGATGTGCTCTATAC
AGGCAGAACCATCCGTTCCGCACTTGAAGCTATTCTTGATTACGGCCGGCCGGAGAGGGTCGAGCTGCTGGTTCTGGTGG
ACAGAGGGCATAGAGAGCTGCCTATACATGCTGATTATGTGGGCAAGTCACTCACAACAGGCAGGGACGAGCAGGTCAAT
GTCCTTGTGTCGGAGCGTGACGGCGACGATGCTGTGATGCTGTTGCGCCGCTAG

Upstream 100 bases:

>100_bases
AAAGTCAAATGCGGTTTGTGGCTGTCCATTTGCCTTGCCCCGCATAACGCTATACATATGGGGACGCAAAAAGCTAACGC
AAGACCGGAAAGGGTTTTTT

Downstream 100 bases:

>100_bases
CAAGAGATTGTCCGGCATGCATGTTGTCCGGCAGGCGGAACCCGGCGGTTCCGCCTGCCGGTTGTAATCAGGAACAGGCC
CTGGTGATCTCCGTACCGAT

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MQKKCILSAQDIARTLERLACEVLERHGDADNLALVGIQRRGVDIAGRLRGLLSARLGREVALGSLDINLYRDDWTSLDT
QPMINRTELPFAVDDARIVLVDDVLYTGRTIRSALEAILDYGRPERVELLVLVDRGHRELPIHADYVGKSLTTGRDEQVN
VLVSERDGDDAVMLLRR

Sequences:

>Translated_177_residues
MQKKCILSAQDIARTLERLACEVLERHGDADNLALVGIQRRGVDIAGRLRGLLSARLGREVALGSLDINLYRDDWTSLDT
QPMINRTELPFAVDDARIVLVDDVLYTGRTIRSALEAILDYGRPERVELLVLVDRGHRELPIHADYVGKSLTTGRDEQVN
VLVSERDGDDAVMLLRR
>Mature_177_residues
MQKKCILSAQDIARTLERLACEVLERHGDADNLALVGIQRRGVDIAGRLRGLLSARLGREVALGSLDINLYRDDWTSLDT
QPMINRTELPFAVDDARIVLVDDVLYTGRTIRSALEAILDYGRPERVELLVLVDRGHRELPIHADYVGKSLTTGRDEQVN
VLVSERDGDDAVMLLRR

Specific function: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 19857; Mature: 19857

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKKCILSAQDIARTLERLACEVLERHGDADNLALVGIQRRGVDIAGRLRGLLSARLGRE
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCE
VALGSLDINLYRDDWTSLDTQPMINRTELPFAVDDARIVLVDDVLYTGRTIRSALEAILD
EEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEEECCHHCCHHHHHHHHHHHH
YGRPERVELLVLVDRGHRELPIHADYVGKSLTTGRDEQVNVLVSERDGDDAVMLLRR
CCCCCEEEEEEEEECCCCCCCEEHHHCCCCCCCCCCCEEEEEEECCCCCCEEEEEEC
>Mature Secondary Structure
MQKKCILSAQDIARTLERLACEVLERHGDADNLALVGIQRRGVDIAGRLRGLLSARLGRE
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCE
VALGSLDINLYRDDWTSLDTQPMINRTELPFAVDDARIVLVDDVLYTGRTIRSALEAILD
EEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEEECCHHCCHHHHHHHHHHHH
YGRPERVELLVLVDRGHRELPIHADYVGKSLTTGRDEQVNVLVSERDGDDAVMLLRR
CCCCCEEEEEEEEECCCCCCCEEHHHCCCCCCCCCCCEEEEEEECCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]