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The map label for this gene is ppiC [H]

Identifier: 78357053

GI number: 78357053

Start: 2051634

End: 2051915

Strand: Reverse

Name: ppiC [H]

Synonym: Dde_2010

Alternate gene names: 78357053

Gene position: 2051915-2051634 (Counterclockwise)

Preceding gene: 78357055

Following gene: 78357052

Centisome position: 55.01

GC content: 52.84

Gene sequence:

>282_bases
ATGCAAACTGCAAGTGCAAGACACATTCTTGTGAATACTGAAGAAGCCTGCCTTGAGCTGAAAAAACGCATCGAAGCCGG
TGAGGCTTTTGCTGATATCGCCCGCGAACATTCCCGCTGCCCGTCCGGCCGCAGGGGCGGAGATCTCGGTAAATTCCGCA
AGGGCCAGATGGTACCGGAGTTTGATGAAGTCGTGTTCAGCGGCGATCTGAACGTGGTGCACGGTCCTGTGCGTACCCAG
TTCGGTTTTCATCTTCTTGAAATCACAGAGCGTTCAGAATAA

Upstream 100 bases:

>100_bases
CGCACGACGGCGCTACGCAAGGCGAATCATGTTGCATCGTGCCGTCTGTCGTGGCAAAAGGCATGATATCACTTGTGACG
ACCAATCCCAGGAGGACAAA

Downstream 100 bases:

>100_bases
AATTTTTGAAACTTCTGTTGATTAAGGGCGCCTGCGGGCGCCTTTTTTTATATCTTTTTCCTGTTATGTCTTTTTTTGGC
AAACATGTTCACCTCATTGG

Product: peptidyl-prolyl cis-trans isomerase C

Products: NA

Alternate protein names: PPIase C; Parvulin; Rotamase C [H]

Number of amino acids: Translated: 93; Mature: 93

Protein sequence:

>93_residues
MQTASARHILVNTEEACLELKKRIEAGEAFADIAREHSRCPSGRRGGDLGKFRKGQMVPEFDEVVFSGDLNVVHGPVRTQ
FGFHLLEITERSE

Sequences:

>Translated_93_residues
MQTASARHILVNTEEACLELKKRIEAGEAFADIAREHSRCPSGRRGGDLGKFRKGQMVPEFDEVVFSGDLNVVHGPVRTQ
FGFHLLEITERSE
>Mature_93_residues
MQTASARHILVNTEEACLELKKRIEAGEAFADIAREHSRCPSGRRGGDLGKFRKGQMVPEFDEVVFSGDLNVVHGPVRTQ
FGFHLLEITERSE

Specific function: PPIases accelerate the folding of proteins. It prefers amino acid residues with hydrophobic side chains like leucine and phenylalanine in the P1 position of the peptides substrates [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1790211, Length=91, Percent_Identity=51.6483516483517, Blast_Score=104, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 10411; Mature: 10411

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTASARHILVNTEEACLELKKRIEAGEAFADIAREHSRCPSGRRGGDLGKFRKGQMVPE
CCCCCCCEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
FDEVVFSGDLNVVHGPVRTQFGFHLLEITERSE
HHHEEECCCCCEEECCHHHCCCCCEEEECCCCC
>Mature Secondary Structure
MQTASARHILVNTEEACLELKKRIEAGEAFADIAREHSRCPSGRRGGDLGKFRKGQMVPE
CCCCCCCEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
FDEVVFSGDLNVVHGPVRTQFGFHLLEITERSE
HHHEEECCCCCEEECCHHHCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]