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The map label for this gene is ltaE [H]

Identifier: 78356700

GI number: 78356700

Start: 1709228

End: 1710247

Strand: Direct

Name: ltaE [H]

Synonym: Dde_1657

Alternate gene names: 78356700

Gene position: 1709228-1710247 (Clockwise)

Preceding gene: 78356699

Following gene: 78356702

Centisome position: 45.82

GC content: 58.14

Gene sequence:

>1020_bases
GTGAAGAGCTTTGCCAGTGACAATACGGCGGGGGCGCATCCCAGAATTCTGAATGCATTGGCCCGGGCCAATGAAGGACA
TGCTGCCCCGTATGGTAACGACCCTTTCACCGCTCAGGCGCAGGAGTGCTTCCGCCGCATTTTCGGTGAGGAAACGCATG
TGTTTCCCGTTTTTGCGGGAACGGCAGCCAATGTGCTGGCATTGCGAGGAGCTCTCAAACCGTGGCAGGCGGTGGTATGC
TCTGATGTGGCCCACATCAATGTGGATGAAACCGGTGCCCCGGAAGCCATGGGCGGTATGAAACTTGTGGCGCTGCCTTC
AAAAAATGGCAAGCTGACTGCCGCCTGTCTGGAGCCTGCCTTTGAGCAGATAGGAGTTGTGCACCACGCTCAGCCGGGTG
TTGTGTCCATCACGCAGGTAACGGAATACGGAACCGTGTACACGCCGGACGAAGTTCGTGCCATTGCCGATGCAGTCCAC
GGGCGGGGGTTGCTGCTGCATATGGACGGCGCCCGCATTGCCAACGCCGCCGCGGCACTGGGGCTTACGCTGCGGGAACT
GACACGGGATGCGGGAGTGGATGTGCTGACTTTCGGCGGAACTAAAAACGGTCTCTTTTTTGGCGATGCCGTGGTTGTTT
TTGATGAGCGCCTTGCAGAAGGTTATGCCTACCTGCGCAAACAGACGGGCCAGCTTTGTTCAAAGATGCGTTTTATCAGT
GCGCAGTTCGTTGAGCTTTTGAAGGACGGTCTGTGGCTTGAAAATGCGCGCCACGCCAATGCCATGGCTTCCGTTCTGGC
ACAGGGACTGTCCGGCATCGATGCCGTATCCATAACGCGTCCGGTACAGGCCAACGCTGTCTTTGCCTGTCTGCCTGCAC
GCGGTGTTGCGGCGCTGCAGCGCGAGTATCTTTTCAATGTGTGGGATGCCGCAACGGGCGAAGTGCGCCTGATGACGTCG
TTTGCCACCACGGAAGACGAAGTGGCCGAATTTGTACAGGCTGTCCGCGCAGCTTGCTGA

Upstream 100 bases:

>100_bases
CGGGAACGGGATTTTCTTGATACGACACTCGCCATGTACGAACAGGCATAGTCTGTCCGTCTGTGCAGGGTATAACATCT
CCGACGACAAGGAATACATA

Downstream 100 bases:

>100_bases
CGCCCTTTCGTCCGGATGGAAAATCAAGGCGCGGCAGACTGTCAGGCTGCCGCGCCTTGTTGTTATCTGCGCAGAAACGA
ATAAATCCGCGCTGCCGCGG

Product: L-threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKSFASDNTAGAHPRILNALARANEGHAAPYGNDPFTAQAQECFRRIFGEETHVFPVFAGTAANVLALRGALKPWQAVVC
SDVAHINVDETGAPEAMGGMKLVALPSKNGKLTAACLEPAFEQIGVVHHAQPGVVSITQVTEYGTVYTPDEVRAIADAVH
GRGLLLHMDGARIANAAAALGLTLRELTRDAGVDVLTFGGTKNGLFFGDAVVVFDERLAEGYAYLRKQTGQLCSKMRFIS
AQFVELLKDGLWLENARHANAMASVLAQGLSGIDAVSITRPVQANAVFACLPARGVAALQREYLFNVWDAATGEVRLMTS
FATTEDEVAEFVQAVRAAC

Sequences:

>Translated_339_residues
MKSFASDNTAGAHPRILNALARANEGHAAPYGNDPFTAQAQECFRRIFGEETHVFPVFAGTAANVLALRGALKPWQAVVC
SDVAHINVDETGAPEAMGGMKLVALPSKNGKLTAACLEPAFEQIGVVHHAQPGVVSITQVTEYGTVYTPDEVRAIADAVH
GRGLLLHMDGARIANAAAALGLTLRELTRDAGVDVLTFGGTKNGLFFGDAVVVFDERLAEGYAYLRKQTGQLCSKMRFIS
AQFVELLKDGLWLENARHANAMASVLAQGLSGIDAVSITRPVQANAVFACLPARGVAALQREYLFNVWDAATGEVRLMTS
FATTEDEVAEFVQAVRAAC
>Mature_339_residues
MKSFASDNTAGAHPRILNALARANEGHAAPYGNDPFTAQAQECFRRIFGEETHVFPVFAGTAANVLALRGALKPWQAVVC
SDVAHINVDETGAPEAMGGMKLVALPSKNGKLTAACLEPAFEQIGVVHHAQPGVVSITQVTEYGTVYTPDEVRAIADAVH
GRGLLLHMDGARIANAAAALGLTLRELTRDAGVDVLTFGGTKNGLFFGDAVVVFDERLAEGYAYLRKQTGQLCSKMRFIS
AQFVELLKDGLWLENARHANAMASVLAQGLSGIDAVSITRPVQANAVFACLPARGVAALQREYLFNVWDAATGEVRLMTS
FATTEDEVAEFVQAVRAAC

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320789, Length=293, Percent_Identity=26.6211604095563, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 36071; Mature: 36071

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFASDNTAGAHPRILNALARANEGHAAPYGNDPFTAQAQECFRRIFGEETHVFPVFAG
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECC
TAANVLALRGALKPWQAVVCSDVAHINVDETGAPEAMGGMKLVALPSKNGKLTAACLEPA
CHHHHHHHHHCCCHHHHHHHCCHHEECCCCCCCCHHHCCEEEEEECCCCCCEEHHHHHHH
FEQIGVVHHAQPGVVSITQVTEYGTVYTPDEVRAIADAVHGRGLLLHMDGARIANAAAAL
HHHHCCCCCCCCCEEEEEEECCCCCEECCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHH
GLTLRELTRDAGVDVLTFGGTKNGLFFGDAVVVFDERLAEGYAYLRKQTGQLCSKMRFIS
HHHHHHHHHHCCCEEEEECCCCCCEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQFVELLKDGLWLENARHANAMASVLAQGLSGIDAVSITRPVQANAVFACLPARGVAALQ
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCCHHHHHH
REYLFNVWDAATGEVRLMTSFATTEDEVAEFVQAVRAAC
HHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSFASDNTAGAHPRILNALARANEGHAAPYGNDPFTAQAQECFRRIFGEETHVFPVFAG
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECC
TAANVLALRGALKPWQAVVCSDVAHINVDETGAPEAMGGMKLVALPSKNGKLTAACLEPA
CHHHHHHHHHCCCHHHHHHHCCHHEECCCCCCCCHHHCCEEEEEECCCCCCEEHHHHHHH
FEQIGVVHHAQPGVVSITQVTEYGTVYTPDEVRAIADAVHGRGLLLHMDGARIANAAAAL
HHHHCCCCCCCCCEEEEEEECCCCCEECCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHH
GLTLRELTRDAGVDVLTFGGTKNGLFFGDAVVVFDERLAEGYAYLRKQTGQLCSKMRFIS
HHHHHHHHHHCCCEEEEECCCCCCEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQFVELLKDGLWLENARHANAMASVLAQGLSGIDAVSITRPVQANAVFACLPARGVAALQ
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCCHHHHHH
REYLFNVWDAATGEVRLMTSFATTEDEVAEFVQAVRAAC
HHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]