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The map label for this gene is gmhB [H]

Identifier: 78356526

GI number: 78356526

Start: 1500136

End: 1500816

Strand: Direct

Name: gmhB [H]

Synonym: Dde_1481

Alternate gene names: 78356526

Gene position: 1500136-1500816 (Clockwise)

Preceding gene: 78356517

Following gene: 78356527

Centisome position: 40.22

GC content: 60.06

Gene sequence:

>681_bases
ATGCTGTCCGCCGCGATTCAATTTGTTTCGCCCCTGACCCAGCTGCATGAAGGAGGCTCAGTGCCCCGTATTGACTGTAT
TCTTCTTGACCGTGACGGTACGGTCATCGTCGACAAGCATTATCTGAGCGACCCGCAGGGCGTTGAACTGCTGCCGGGGG
CCGGAGAAGCATTGGCCGGAGCCTGTGCCGAAGGCAGAAAGCTGTTCATCGTGACCAATCAGTCCGGTATCGGGCGGGGA
ATGTTTTCGGAAAACGACTACGAGGCGTGCAGGATGCAGCTTGACGCCATGCTGCAATCCTGCGGCGCGTCGGTCACTGC
TTCGCGCCATTGTCCGCATGCTCCTGACAGTTCCTGCATATGCCGCAAGCCGGAGACAGGCCTGTGGCAGACCCTGCGCG
ATGCCTACGGGCTGAAGGCGGAGCGCTGCGTGATGGTGGGCGACAAGCTGGCTGATGTGGGCTTCGGGCGCAACGCCTGT
CTGGCTGCTTCTGTGCTGGTACTTACCGGCAAAGGGCGGGCAGAGGCGGAAAAGGCCGGATTGAAAGCGGAAGCTGATAT
GGCGTTGCGTGAGGACGGCTGGGTTGAAGTGCATAAACGCTCAGGCGTGCTGCCGGATGTTGTGGCATGCGATGTGCGTG
CCGCGCTCGACTGGGTAAGAACTGTGCTGGAGGAGAAATAA

Upstream 100 bases:

>100_bases
TGCCGCCGGTGTGCGGGGCCTGCGGCCGCCGTGCGCCTTGCAAAAACATAACTGCCGTGCCATCTAGACACGCCTGTTGC
GTGGTGTGTGCGGCAGGATT

Downstream 100 bases:

>100_bases
TGCGACGCATAGCCGTCTGGAACACCGCTTTTCTCGGCGATGCCGTGCTGACGCTGCCGCTTATCAGCACGCTGAAGGCT
GCCTATCCTGATGCCGCCAT

Product: HAD family hydrolase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MLSAAIQFVSPLTQLHEGGSVPRIDCILLDRDGTVIVDKHYLSDPQGVELLPGAGEALAGACAEGRKLFIVTNQSGIGRG
MFSENDYEACRMQLDAMLQSCGASVTASRHCPHAPDSSCICRKPETGLWQTLRDAYGLKAERCVMVGDKLADVGFGRNAC
LAASVLVLTGKGRAEAEKAGLKAEADMALREDGWVEVHKRSGVLPDVVACDVRAALDWVRTVLEEK

Sequences:

>Translated_226_residues
MLSAAIQFVSPLTQLHEGGSVPRIDCILLDRDGTVIVDKHYLSDPQGVELLPGAGEALAGACAEGRKLFIVTNQSGIGRG
MFSENDYEACRMQLDAMLQSCGASVTASRHCPHAPDSSCICRKPETGLWQTLRDAYGLKAERCVMVGDKLADVGFGRNAC
LAASVLVLTGKGRAEAEKAGLKAEADMALREDGWVEVHKRSGVLPDVVACDVRAALDWVRTVLEEK
>Mature_226_residues
MLSAAIQFVSPLTQLHEGGSVPRIDCILLDRDGTVIVDKHYLSDPQGVELLPGAGEALAGACAEGRKLFIVTNQSGIGRG
MFSENDYEACRMQLDAMLQSCGASVTASRHCPHAPDSSCICRKPETGLWQTLRDAYGLKAERCVMVGDKLADVGFGRNAC
LAASVLVLTGKGRAEAEKAGLKAEADMALREDGWVEVHKRSGVLPDVVACDVRAALDWVRTVLEEK

Specific function: Converts the D-glycero-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=169, Percent_Identity=37.2781065088757, Blast_Score=98, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 24184; Mature: 24184

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSAAIQFVSPLTQLHEGGSVPRIDCILLDRDGTVIVDKHYLSDPQGVELLPGAGEALAG
CCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEHHHCCCCCCCEECCCCCHHHHH
ACAEGRKLFIVTNQSGIGRGMFSENDYEACRMQLDAMLQSCGASVTASRHCPHAPDSSCI
HHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCE
CRKPETGLWQTLRDAYGLKAERCVMVGDKLADVGFGRNACLAASVLVLTGKGRAEAEKAG
ECCCCCHHHHHHHHHHCCCCCEEEEECCHHHHCCCCCCHHHHEEEEEEECCCCCHHHHCC
LKAEADMALREDGWVEVHKRSGVLPDVVACDVRAALDWVRTVLEEK
CCCCCCHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLSAAIQFVSPLTQLHEGGSVPRIDCILLDRDGTVIVDKHYLSDPQGVELLPGAGEALAG
CCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEHHHCCCCCCCEECCCCCHHHHH
ACAEGRKLFIVTNQSGIGRGMFSENDYEACRMQLDAMLQSCGASVTASRHCPHAPDSSCI
HHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCE
CRKPETGLWQTLRDAYGLKAERCVMVGDKLADVGFGRNACLAASVLVLTGKGRAEAEKAG
ECCCCCHHHHHHHHHHCCCCCEEEEECCHHHHCCCCCCHHHHEEEEEEECCCCCHHHHCC
LKAEADMALREDGWVEVHKRSGVLPDVVACDVRAALDWVRTVLEEK
CCCCCCHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11121031 [H]