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The map label for this gene is argD [H]

Identifier: 78356471

GI number: 78356471

Start: 1452199

End: 1453401

Strand: Direct

Name: argD [H]

Synonym: Dde_1426

Alternate gene names: 78356471

Gene position: 1452199-1453401 (Clockwise)

Preceding gene: 78356470

Following gene: 78356472

Centisome position: 38.93

GC content: 59.93

Gene sequence:

>1203_bases
ATGACTACGTTCGATGAATTGAAACAGCGTGAAGAATCTCTGCTCTGCAGAACATACGGCAGATATCCGCTGGCTGTTGC
GTCCGCCCGGGGCAGTGTTCTGACAGATTTTTCCGGCAGGGAATACATTGACCTGCTTTCAGGCATAGCCGTTACCAATC
TGGGACATTGCCATCCCGCTCTTGCAGAGGTCATGCACGCGCAGGCCGGCAGGCTGGTGCATCTTTCCAATCTGTTTTAC
CAGCAGGAACAGCTGGAGCTGGCGGAAAAACTGCTCGGCACCACCCATCTGGGCAAGGCGTTTTTCTGCAATTCCGGCGC
AGAAGCCAACGAAGCGGCCATAAAGCTGGCCCGCCGCTATGCGCAGCGGGTCAAGGAACGCGATGCCGGTACGGTGATAA
CGCTTACAGGCGCTTTTCACGGCAGAACGCTTGCCACTGTGGCAGCCACGGGGCAGGCAAAGTTTCAGGACGGCTTTGCG
CCCATCCCGCAGGGTTTCCGGCAGGTGGAGTGGGGCAGCCTGGATGCGCTGGAAGCGGCCATGGATGACGACGTGGTGGC
CGTGCTGGCCGAAATTGTGCAAGGCGAAGGCGGTATCCGCCCCATGACCCCGGAATATGCACAGGGTGTGCAGGATATCT
GCCGCCGTCACGGGGTGCTTTTCATGGTGGACGAAGTGCAGTCGGGCATGTGCCGTACCGGAAGGTTCTGGGCTTTTCAG
CATTACGGACTGACGCCCGATGTGGTCACCAGCGCCAAGGCGCTGGCCAACGGGCTGCCCATGGGAGCCATGCTGGCCAC
CGACGAAGCCGCTAAAGGGTTTGAACCCGGCAGCCACGCCACCACCTTTGGCGCCGGAGCTCTTGTTTCGGCTGTGGCGG
CCCGTGTTGTGGATATCATGCAGCAGGAAAAGCTTGCCGAACGCGCCGATCGGGTGGGCGGGGCTTTCATGGCTGATGTG
CGCAGTCTGGCCGCCCGTCTGCCCGGTACCATACAGGAGGTACGCGGGCTGGGGCTTATGATAGGCATTGTGCTGACATT
TCCCGGCAGGGAAGTGTGGGAAGAGCTGCTCCGGCGCGGTTTTGTGCTTAATCTGACGCAGGAACGGGTATTGCGCCTGT
TGCCTGCGCTGACAGTGCCGGAAACGTACCTGCAGGACTTTCTGACTGCGCTGGAAGAAATACTGAGCGAGCGCACTGTA
TAG

Upstream 100 bases:

>100_bases
GCTGGGCGATACGCAGCGCGGAACCGGCGGCTTCGGTCATACGGGACGTATCTGATCCCGTCTTTTTCTCAGCTTTTTTC
CGGCACAGGAGTGCATTGCA

Downstream 100 bases:

>100_bases
TTTTTCACCGGTACTTTTTGATCTGGTGATGAAATTGTCAACGGTGCAGCCTGATGCGGGCTGCACCGTTTTTTTGTGCC
TTTCCGCCAGCAGGGCGGAA

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTTFDELKQREESLLCRTYGRYPLAVASARGSVLTDFSGREYIDLLSGIAVTNLGHCHPALAEVMHAQAGRLVHLSNLFY
QQEQLELAEKLLGTTHLGKAFFCNSGAEANEAAIKLARRYAQRVKERDAGTVITLTGAFHGRTLATVAATGQAKFQDGFA
PIPQGFRQVEWGSLDALEAAMDDDVVAVLAEIVQGEGGIRPMTPEYAQGVQDICRRHGVLFMVDEVQSGMCRTGRFWAFQ
HYGLTPDVVTSAKALANGLPMGAMLATDEAAKGFEPGSHATTFGAGALVSAVAARVVDIMQQEKLAERADRVGGAFMADV
RSLAARLPGTIQEVRGLGLMIGIVLTFPGREVWEELLRRGFVLNLTQERVLRLLPALTVPETYLQDFLTALEEILSERTV

Sequences:

>Translated_400_residues
MTTFDELKQREESLLCRTYGRYPLAVASARGSVLTDFSGREYIDLLSGIAVTNLGHCHPALAEVMHAQAGRLVHLSNLFY
QQEQLELAEKLLGTTHLGKAFFCNSGAEANEAAIKLARRYAQRVKERDAGTVITLTGAFHGRTLATVAATGQAKFQDGFA
PIPQGFRQVEWGSLDALEAAMDDDVVAVLAEIVQGEGGIRPMTPEYAQGVQDICRRHGVLFMVDEVQSGMCRTGRFWAFQ
HYGLTPDVVTSAKALANGLPMGAMLATDEAAKGFEPGSHATTFGAGALVSAVAARVVDIMQQEKLAERADRVGGAFMADV
RSLAARLPGTIQEVRGLGLMIGIVLTFPGREVWEELLRRGFVLNLTQERVLRLLPALTVPETYLQDFLTALEEILSERTV
>Mature_399_residues
TTFDELKQREESLLCRTYGRYPLAVASARGSVLTDFSGREYIDLLSGIAVTNLGHCHPALAEVMHAQAGRLVHLSNLFYQ
QEQLELAEKLLGTTHLGKAFFCNSGAEANEAAIKLARRYAQRVKERDAGTVITLTGAFHGRTLATVAATGQAKFQDGFAP
IPQGFRQVEWGSLDALEAAMDDDVVAVLAEIVQGEGGIRPMTPEYAQGVQDICRRHGVLFMVDEVQSGMCRTGRFWAFQH
YGLTPDVVTSAKALANGLPMGAMLATDEAAKGFEPGSHATTFGAGALVSAVAARVVDIMQQEKLAERADRVGGAFMADVR
SLAARLPGTIQEVRGLGLMIGIVLTFPGREVWEELLRRGFVLNLTQERVLRLLPALTVPETYLQDFLTALEEILSERTV

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=402, Percent_Identity=33.0845771144279, Blast_Score=231, Evalue=9e-61,
Organism=Homo sapiens, GI284507298, Length=303, Percent_Identity=34.983498349835, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI13994255, Length=381, Percent_Identity=29.9212598425197, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI37574042, Length=426, Percent_Identity=28.8732394366197, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI24119277, Length=372, Percent_Identity=30.9139784946237, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI226442709, Length=395, Percent_Identity=29.3670886075949, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI226442705, Length=426, Percent_Identity=28.169014084507, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI188536080, Length=435, Percent_Identity=25.2873563218391, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI38679950, Length=435, Percent_Identity=25.2873563218391, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI38679946, Length=435, Percent_Identity=25.2873563218391, Blast_Score=119, Evalue=7e-27,
Organism=Escherichia coli, GI1788044, Length=397, Percent_Identity=39.0428211586902, Blast_Score=294, Evalue=8e-81,
Organism=Escherichia coli, GI1789759, Length=389, Percent_Identity=39.3316195372751, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI145693181, Length=368, Percent_Identity=34.2391304347826, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1787560, Length=426, Percent_Identity=32.8638497652582, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1789016, Length=430, Percent_Identity=30.4651162790698, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1786991, Length=344, Percent_Identity=31.1046511627907, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786349, Length=255, Percent_Identity=28.2352941176471, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI25144271, Length=383, Percent_Identity=33.420365535248, Blast_Score=231, Evalue=5e-61,
Organism=Caenorhabditis elegans, GI32564660, Length=372, Percent_Identity=31.989247311828, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI25144274, Length=272, Percent_Identity=31.9852941176471, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71992977, Length=446, Percent_Identity=30.7174887892377, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17541228, Length=454, Percent_Identity=26.2114537444934, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71981843, Length=174, Percent_Identity=32.183908045977, Blast_Score=102, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6324432, Length=401, Percent_Identity=32.1695760598504, Blast_Score=240, Evalue=4e-64,
Organism=Saccharomyces cerevisiae, GI6323470, Length=410, Percent_Identity=31.9512195121951, Blast_Score=212, Evalue=7e-56,
Organism=Saccharomyces cerevisiae, GI6324386, Length=439, Percent_Identity=24.373576309795, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321456, Length=431, Percent_Identity=23.8979118329466, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21357415, Length=395, Percent_Identity=31.6455696202532, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI28574759, Length=436, Percent_Identity=27.7522935779816, Blast_Score=171, Evalue=6e-43,
Organism=Drosophila melanogaster, GI161085790, Length=450, Percent_Identity=27.7777777777778, Blast_Score=171, Evalue=8e-43,
Organism=Drosophila melanogaster, GI21356575, Length=443, Percent_Identity=29.1196388261851, Blast_Score=144, Evalue=9e-35,
Organism=Drosophila melanogaster, GI281366494, Length=394, Percent_Identity=24.3654822335025, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24667139, Length=394, Percent_Identity=24.3654822335025, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24667143, Length=394, Percent_Identity=24.3654822335025, Blast_Score=105, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43451; Mature: 43320

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFDELKQREESLLCRTYGRYPLAVASARGSVLTDFSGREYIDLLSGIAVTNLGHCHPA
CCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHCCCCCCHH
LAEVMHAQAGRLVHLSNLFYQQEQLELAEKLLGTTHLGKAFFCNSGAEANEAAIKLARRY
HHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCHHHHHHHHHHHH
AQRVKERDAGTVITLTGAFHGRTLATVAATGQAKFQDGFAPIPQGFRQVEWGSLDALEAA
HHHHHHCCCCCEEEEECCCCCCCHHHHEECCCHHHCCCCCCHHHHHHHCCCCCHHHHHHH
MDDDVVAVLAEIVQGEGGIRPMTPEYAQGVQDICRRHGVLFMVDEVQSGMCRTGRFWAFQ
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEHHHCCCCCCCCEEEEE
HYGLTPDVVTSAKALANGLPMGAMLATDEAAKGFEPGSHATTFGAGALVSAVAARVVDIM
CCCCCHHHHHHHHHHHCCCCCCHHEECCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QQEKLAERADRVGGAFMADVRSLAARLPGTIQEVRGLGLMIGIVLTFPGREVWEELLRRG
HHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
FVLNLTQERVLRLLPALTVPETYLQDFLTALEEILSERTV
CEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTFDELKQREESLLCRTYGRYPLAVASARGSVLTDFSGREYIDLLSGIAVTNLGHCHPA
CCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHCCCCCCHH
LAEVMHAQAGRLVHLSNLFYQQEQLELAEKLLGTTHLGKAFFCNSGAEANEAAIKLARRY
HHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCHHHHHHHHHHHH
AQRVKERDAGTVITLTGAFHGRTLATVAATGQAKFQDGFAPIPQGFRQVEWGSLDALEAA
HHHHHHCCCCCEEEEECCCCCCCHHHHEECCCHHHCCCCCCHHHHHHHCCCCCHHHHHHH
MDDDVVAVLAEIVQGEGGIRPMTPEYAQGVQDICRRHGVLFMVDEVQSGMCRTGRFWAFQ
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEHHHCCCCCCCCEEEEE
HYGLTPDVVTSAKALANGLPMGAMLATDEAAKGFEPGSHATTFGAGALVSAVAARVVDIM
CCCCCHHHHHHHHHHHCCCCCCHHEECCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QQEKLAERADRVGGAFMADVRSLAARLPGTIQEVRGLGLMIGIVLTFPGREVWEELLRRG
HHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
FVLNLTQERVLRLLPALTVPETYLQDFLTALEEILSERTV
CEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]