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The map label for this gene is ppiD [H]

Identifier: 78356452

GI number: 78356452

Start: 1424903

End: 1426792

Strand: Direct

Name: ppiD [H]

Synonym: Dde_1407

Alternate gene names: 78356452

Gene position: 1424903-1426792 (Clockwise)

Preceding gene: 78356451

Following gene: 78356453

Centisome position: 38.2

GC content: 56.08

Gene sequence:

>1890_bases
ATGCTGGACTCAATAAGACAGAACGCCCAGTCGTGGGGCGTTAAAATCGCCTTCGGGCTTATCATCATCGTGTTTGTCTT
CTGGGGCGTCGGCTCCATGGACAATCAGCCTTCCAATGTGGTGGCAAAGGTGGGCAAAACGTCCATCACCGTCAATGCCT
TTGCCAGAGAATATGAACAGCAGGTCGAGCTTGTCCGTGCTCAGTTTCCGGACGTGACCTCGGAAGATCTGAAGCAGGCG
GGGCTGAAAATGCGCGTTCTGAATCAGATGATTTCCGAAGTGCTGCTTGTGCAGCAGGCCGAAAAGCAGGGGCTGGAGGT
TTCTCCCGCCGAACTGAAGCTGCGTATCGCCGAGATTCCCGTGTTCAACGATGCCGATGGCAACTTTGACGGTGAGCGTT
ACAAACAGGTGCTGGCTGCACAGGGTACCACACCCGGCGCGTACGAAGACAAGATCCGTCGTTCCATGCTGGCGCAGAAA
ATGCGTGATTTCATCACCATGCCTGCCGCCGTCACCGCAGAAGAAGCCAAAGCCATGTTCCTGTATTCTGCAGAACGCAG
AAGCATGGATTATGTGCTTTTTGCCGCGGAAAACTATCTGGATCAGGTGAAGCCCGGCGAAGAGCAGATTTCCGCTTTTT
ACAAGCAGAATATTGAAAATTATAAAGTGCCCCCGCGCGTGACGCTGCAGTACGTGATGATCACTCCTGCGGCACTGGCC
GACGGCGCTTCTGTCTCTGATGACCGCATAGCTGCCTATTACGAAGACAATAAAGAATCATTCCGTCAGGAAGAACGGGT
GCACGCCCGTCACATTCTGGTTCTGGCAGATGCCGGTGCGTCGGAAGAAAAGGTGGCCGCGGCTGAGAAAAAGATAAACG
AATTGTATGAGCGGATCCGCAAGGGTGCTGATTTTGCCAAGGTGGCCAAAGAAGCCTCTGAAGGGCCCAGTGCTCCGCTT
GGCGGCGATCTGGGCTGGTTCGGTCGCGGACAGATGGTACCTGAGTTTGAGCAGGCAGCCTTTGCCGCTGCCGCCGGGCA
GGTAACCGCACCTGTGCGCACGCAGTTCGGTTTCCACATCATTAAAGTGGAAGAAAAAGAAAACGCCCGTATCCGCACGC
TGGACGAAGTGCATGATGAGATTTCGCACCGTCTGGCCGAAGAGGCGGCGCTGGAAAAGGTTACTCCCACTCTGGACGCC
GCACTGGAAGCACTGCTTGCCGGTGAAGACCTGCCTGCCGTGGCGGAGCGCATGCACCTTTCCCTGCGTGACAGCGGTCA
GTTCACCCGCGCTCAGGCCACCGGCCTGCTTGGTGTTGAACCTGCATCTGTCGAGCTTATTTTCACCACGCCCGAAGGGT
CTGTCATTGACACGCCCATGGAAGTGGAAGGTGGCTACATGCTGGCCAAGGTTGTTTCCAGCAAGGAAGAAACCTACCGC
GAGCTGGACGTTGTGAAGGCGGACGTCATCGCCCGTCTGAAGCAGCAGGAAGCCATGAAGCTGGCCGCTGATGCTGCGCG
CGAAGCCGTAGCAGCGCTGAAGAACGACGGTTCTCTGCCGCAGTCTGCAGCAGCCCGTGTGAAGAGAAGCGAACCTTTCG
GCCGTCAGGGCTTTATTCCCGGTGTGGGACAGGCTCCTGATGTGACTTCCGCCATATTCAAGGCTGCCGATGACGCATGG
ATAGCTGAAGCGTTTCAGACTCCCACCGGTGCTGTTGTGGCTAAGCGCGCCGCTGTGCTTACCCCCGATGAAACTCAGTG
GGCGCAGGTTAAAGACCGTTTTGTTGACGCCATGCTGCAGAGCAAGCGCGAAGAGCTGTACCGTGCCTACATGCAGGACC
TGCTTACCAAAACAAAGGTTGAGCTGGTGAACAACAAGATTCTTGAGTAA

Upstream 100 bases:

>100_bases
TGGACATTATTCGGGCAGGCGGATTGCTTAATTATGTACGTCTCTCGAAAACGGCTGCTGCTTAGCGGCGGCCCATCTGC
TTTGAAAAAACGGAGTGCTC

Downstream 100 bases:

>100_bases
CCGCAGAGCATTCCCGGGCCGCCCTGAAAGGGGCGGCCTTTTTCTGTCTTTACAAAAATCTTTCCGGCCATGCCGGAGAG
ATTTTTTTGTGTTATGGTGT

Product: peptidyl-prolyl cis-trans isomerse domain-containing protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 629; Mature: 629

Protein sequence:

>629_residues
MLDSIRQNAQSWGVKIAFGLIIIVFVFWGVGSMDNQPSNVVAKVGKTSITVNAFAREYEQQVELVRAQFPDVTSEDLKQA
GLKMRVLNQMISEVLLVQQAEKQGLEVSPAELKLRIAEIPVFNDADGNFDGERYKQVLAAQGTTPGAYEDKIRRSMLAQK
MRDFITMPAAVTAEEAKAMFLYSAERRSMDYVLFAAENYLDQVKPGEEQISAFYKQNIENYKVPPRVTLQYVMITPAALA
DGASVSDDRIAAYYEDNKESFRQEERVHARHILVLADAGASEEKVAAAEKKINELYERIRKGADFAKVAKEASEGPSAPL
GGDLGWFGRGQMVPEFEQAAFAAAAGQVTAPVRTQFGFHIIKVEEKENARIRTLDEVHDEISHRLAEEAALEKVTPTLDA
ALEALLAGEDLPAVAERMHLSLRDSGQFTRAQATGLLGVEPASVELIFTTPEGSVIDTPMEVEGGYMLAKVVSSKEETYR
ELDVVKADVIARLKQQEAMKLAADAAREAVAALKNDGSLPQSAAARVKRSEPFGRQGFIPGVGQAPDVTSAIFKAADDAW
IAEAFQTPTGAVVAKRAAVLTPDETQWAQVKDRFVDAMLQSKREELYRAYMQDLLTKTKVELVNNKILE

Sequences:

>Translated_629_residues
MLDSIRQNAQSWGVKIAFGLIIIVFVFWGVGSMDNQPSNVVAKVGKTSITVNAFAREYEQQVELVRAQFPDVTSEDLKQA
GLKMRVLNQMISEVLLVQQAEKQGLEVSPAELKLRIAEIPVFNDADGNFDGERYKQVLAAQGTTPGAYEDKIRRSMLAQK
MRDFITMPAAVTAEEAKAMFLYSAERRSMDYVLFAAENYLDQVKPGEEQISAFYKQNIENYKVPPRVTLQYVMITPAALA
DGASVSDDRIAAYYEDNKESFRQEERVHARHILVLADAGASEEKVAAAEKKINELYERIRKGADFAKVAKEASEGPSAPL
GGDLGWFGRGQMVPEFEQAAFAAAAGQVTAPVRTQFGFHIIKVEEKENARIRTLDEVHDEISHRLAEEAALEKVTPTLDA
ALEALLAGEDLPAVAERMHLSLRDSGQFTRAQATGLLGVEPASVELIFTTPEGSVIDTPMEVEGGYMLAKVVSSKEETYR
ELDVVKADVIARLKQQEAMKLAADAAREAVAALKNDGSLPQSAAARVKRSEPFGRQGFIPGVGQAPDVTSAIFKAADDAW
IAEAFQTPTGAVVAKRAAVLTPDETQWAQVKDRFVDAMLQSKREELYRAYMQDLLTKTKVELVNNKILE
>Mature_629_residues
MLDSIRQNAQSWGVKIAFGLIIIVFVFWGVGSMDNQPSNVVAKVGKTSITVNAFAREYEQQVELVRAQFPDVTSEDLKQA
GLKMRVLNQMISEVLLVQQAEKQGLEVSPAELKLRIAEIPVFNDADGNFDGERYKQVLAAQGTTPGAYEDKIRRSMLAQK
MRDFITMPAAVTAEEAKAMFLYSAERRSMDYVLFAAENYLDQVKPGEEQISAFYKQNIENYKVPPRVTLQYVMITPAALA
DGASVSDDRIAAYYEDNKESFRQEERVHARHILVLADAGASEEKVAAAEKKINELYERIRKGADFAKVAKEASEGPSAPL
GGDLGWFGRGQMVPEFEQAAFAAAAGQVTAPVRTQFGFHIIKVEEKENARIRTLDEVHDEISHRLAEEAALEKVTPTLDA
ALEALLAGEDLPAVAERMHLSLRDSGQFTRAQATGLLGVEPASVELIFTTPEGSVIDTPMEVEGGYMLAKVVSSKEETYR
ELDVVKADVIARLKQQEAMKLAADAAREAVAALKNDGSLPQSAAARVKRSEPFGRQGFIPGVGQAPDVTSAIFKAADDAW
IAEAFQTPTGAVVAKRAAVLTPDETQWAQVKDRFVDAMLQSKREELYRAYMQDLLTKTKVELVNNKILE

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=403, Percent_Identity=28.287841191067, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI1790211, Length=95, Percent_Identity=48.4210526315789, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI1786238, Length=110, Percent_Identity=35.4545454545455, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 69242; Mature: 69242

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDSIRQNAQSWGVKIAFGLIIIVFVFWGVGSMDNQPSNVVAKVGKTSITVNAFAREYEQ
CCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEEHHHHHHHHHH
QVELVRAQFPDVTSEDLKQAGLKMRVLNQMISEVLLVQQAEKQGLEVSPAELKLRIAEIP
HHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEEEEECC
VFNDADGNFDGERYKQVLAAQGTTPGAYEDKIRRSMLAQKMRDFITMPAAVTAEEAKAMF
EECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEE
LYSAERRSMDYVLFAAENYLDQVKPGEEQISAFYKQNIENYKVPPRVTLQYVMITPAALA
EEECCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEECHHHC
DGASVSDDRIAAYYEDNKESFRQEERVHARHILVLADAGASEEKVAAAEKKINELYERIR
CCCCCCCCCEEEEEECCHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
KGADFAKVAKEASEGPSAPLGGDLGWFGRGQMVPEFEQAAFAAAAGQVTAPVRTQFGFHI
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHCCCEEE
IKVEEKENARIRTLDEVHDEISHRLAEEAALEKVTPTLDAALEALLAGEDLPAVAERMHL
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHH
SLRDSGQFTRAQATGLLGVEPASVELIFTTPEGSVIDTPMEVEGGYMLAKVVSSKEETYR
HHCCCCCEEHHHHCCCEECCCCEEEEEEECCCCCEECCCCCCCCCCHHHHHHHHHHHHHH
ELDVVKADVIARLKQQEAMKLAADAAREAVAALKNDGSLPQSAAARVKRSEPFGRQGFIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCC
GVGQAPDVTSAIFKAADDAWIAEAFQTPTGAVVAKRAAVLTPDETQWAQVKDRFVDAMLQ
CCCCCCCHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHEEECCCCHHHHHHHHHHHHHHHH
SKREELYRAYMQDLLTKTKVELVNNKILE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDSIRQNAQSWGVKIAFGLIIIVFVFWGVGSMDNQPSNVVAKVGKTSITVNAFAREYEQ
CCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEEHHHHHHHHHH
QVELVRAQFPDVTSEDLKQAGLKMRVLNQMISEVLLVQQAEKQGLEVSPAELKLRIAEIP
HHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEEEEECC
VFNDADGNFDGERYKQVLAAQGTTPGAYEDKIRRSMLAQKMRDFITMPAAVTAEEAKAMF
EECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEE
LYSAERRSMDYVLFAAENYLDQVKPGEEQISAFYKQNIENYKVPPRVTLQYVMITPAALA
EEECCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEECHHHC
DGASVSDDRIAAYYEDNKESFRQEERVHARHILVLADAGASEEKVAAAEKKINELYERIR
CCCCCCCCCEEEEEECCHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
KGADFAKVAKEASEGPSAPLGGDLGWFGRGQMVPEFEQAAFAAAAGQVTAPVRTQFGFHI
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHCCCEEE
IKVEEKENARIRTLDEVHDEISHRLAEEAALEKVTPTLDAALEALLAGEDLPAVAERMHL
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHH
SLRDSGQFTRAQATGLLGVEPASVELIFTTPEGSVIDTPMEVEGGYMLAKVVSSKEETYR
HHCCCCCEEHHHHCCCEECCCCEEEEEEECCCCCEECCCCCCCCCCHHHHHHHHHHHHHH
ELDVVKADVIARLKQQEAMKLAADAAREAVAALKNDGSLPQSAAARVKRSEPFGRQGFIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCC
GVGQAPDVTSAIFKAADDAWIAEAFQTPTGAVVAKRAAVLTPDETQWAQVKDRFVDAMLQ
CCCCCCCHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHEEECCCCHHHHHHHHHHHHHHHH
SKREELYRAYMQDLLTKTKVELVNNKILE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]