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The map label for this gene is ubiA [H]

Identifier: 78356437

GI number: 78356437

Start: 1409846

End: 1410703

Strand: Direct

Name: ubiA [H]

Synonym: Dde_1392

Alternate gene names: 78356437

Gene position: 1409846-1410703 (Clockwise)

Preceding gene: 78356436

Following gene: 78356438

Centisome position: 37.8

GC content: 55.48

Gene sequence:

>858_bases
ATGACAGTGTTCGGCAGATTCGGCGCGGTGTGCCGCATGGTTAAAATTGAACATTCCGTATTTGCACTGCCTTTCGCCTA
TACCGGCGCATTTATCGCCGCAGGCGGCTGGCCCGGTTGGTATACCATGGTGGTGCTTACCGCGGCCATGGTGGCTGTGC
GCTCTTTTGCCATGGCTTTCAACAGGCTGATAGACCTGCCCGTAGACCGCGCCAACCCCCGTACGCAGGGACGGCCGCTG
GTAACGGGTGAGATAACCCCCGCGCAGACATGGGCCTTTATCGGTGTCATGGCTGCAGTGTTTGTTGCCGCGTGCGCGGC
CATGAACCCGCTGTGTCTCAAGCTGGCACCTGTGGCTTTGTTCATGTCCGCGGTGTACAGCCTGTTCAAACGGTTCACAT
GGGCCTGTCATTTCTTTCTCGGCGCGGTGCTGGGGTTGGCTCCCATTGCCGGATATATTGCCGTGACGCCTGAATTCACC
GTCCCTGTCATTCTTTTCTTCTGGGGCGTGCTGTTCTGGGTGGCCGGTTTTGACATTTTGTATTCGTGTCAGGATGAAGA
CTTTGACAGAAGAGAGGGGCTGCATTCCGTACCGGCCAGAGTAGGCGTGCGTTCGGCGCTTATCGTTTCTTCTTTCTGTC
ATGTGAACACCTCTGTTTTCTTTCTTATGGCCGGATGGGCTGCAGGGCTTTCGTGGCCTTTTTTCGCGGTGTGGGGGCTT
GTCAGTCTTATTCTGCTGGCCGAGCATAAGATAATCTCGGCAGAAGACATGAGCCGGGTTAATATGGCATTCTTCACCAT
GAACGGTGTTGTCTCGGTGGTTGTGTTTGCCGGAGTGCTGCTGGGCATATACATGTAG

Upstream 100 bases:

>100_bases
GACAGCCCAGAGCAAGGCTTTGAAGGAATTCAGAGCGTTTGCCGCCAGACTGGATGATGCGGATCAATAAACTGCAACCC
TTAACAGAACGGAACGGAAG

Downstream 100 bases:

>100_bases
GTTTTTACAGACTGCGGGGAGGCCGCAATGCAGTACAGCATGCAGCAGGAATTTATGCGGCGCAGGGTGCAGGCCATGTA
TAACGAAGTGGCCGTGCCGC

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MTVFGRFGAVCRMVKIEHSVFALPFAYTGAFIAAGGWPGWYTMVVLTAAMVAVRSFAMAFNRLIDLPVDRANPRTQGRPL
VTGEITPAQTWAFIGVMAAVFVAACAAMNPLCLKLAPVALFMSAVYSLFKRFTWACHFFLGAVLGLAPIAGYIAVTPEFT
VPVILFFWGVLFWVAGFDILYSCQDEDFDRREGLHSVPARVGVRSALIVSSFCHVNTSVFFLMAGWAAGLSWPFFAVWGL
VSLILLAEHKIISAEDMSRVNMAFFTMNGVVSVVVFAGVLLGIYM

Sequences:

>Translated_285_residues
MTVFGRFGAVCRMVKIEHSVFALPFAYTGAFIAAGGWPGWYTMVVLTAAMVAVRSFAMAFNRLIDLPVDRANPRTQGRPL
VTGEITPAQTWAFIGVMAAVFVAACAAMNPLCLKLAPVALFMSAVYSLFKRFTWACHFFLGAVLGLAPIAGYIAVTPEFT
VPVILFFWGVLFWVAGFDILYSCQDEDFDRREGLHSVPARVGVRSALIVSSFCHVNTSVFFLMAGWAAGLSWPFFAVWGL
VSLILLAEHKIISAEDMSRVNMAFFTMNGVVSVVVFAGVLLGIYM
>Mature_284_residues
TVFGRFGAVCRMVKIEHSVFALPFAYTGAFIAAGGWPGWYTMVVLTAAMVAVRSFAMAFNRLIDLPVDRANPRTQGRPLV
TGEITPAQTWAFIGVMAAVFVAACAAMNPLCLKLAPVALFMSAVYSLFKRFTWACHFFLGAVLGLAPIAGYIAVTPEFTV
PVILFFWGVLFWVAGFDILYSCQDEDFDRREGLHSVPARVGVRSALIVSSFCHVNTSVFFLMAGWAAGLSWPFFAVWGLV
SLILLAEHKIISAEDMSRVNMAFFTMNGVVSVVVFAGVLLGIYM

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=284, Percent_Identity=25.7042253521127, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1790473, Length=280, Percent_Identity=23.9285714285714, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17553718, Length=248, Percent_Identity=22.9838709677419, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324370, Length=182, Percent_Identity=24.1758241758242, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355567, Length=264, Percent_Identity=23.8636363636364, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 31131; Mature: 31000

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVFGRFGAVCRMVKIEHSVFALPFAYTGAFIAAGGWPGWYTMVVLTAAMVAVRSFAMAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NRLIDLPVDRANPRTQGRPLVTGEITPAQTWAFIGVMAAVFVAACAAMNPLCLKLAPVAL
HHHHCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FMSAVYSLFKRFTWACHFFLGAVLGLAPIAGYIAVTPEFTVPVILFFWGVLFWVAGFDIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHH
YSCQDEDFDRREGLHSVPARVGVRSALIVSSFCHVNTSVFFLMAGWAAGLSWPFFAVWGL
EECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VSLILLAEHKIISAEDMSRVNMAFFTMNGVVSVVVFAGVLLGIYM
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA