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The map label for this gene is mog [H]

Identifier: 78356435

GI number: 78356435

Start: 1407556

End: 1408491

Strand: Direct

Name: mog [H]

Synonym: Dde_1390

Alternate gene names: 78356435

Gene position: 1407556-1408491 (Clockwise)

Preceding gene: 78356434

Following gene: 78356436

Centisome position: 37.73

GC content: 63.68

Gene sequence:

>936_bases
ATGCAAAGACCGGTTCAGGCAGTGACGTCAATTGCCGCGCTGTCCGCTCCGGACAGAAATGTGCGCGGCGCAACGCGGGA
GTCCGGCATGGTGTGTACGGCGGATGTTGATCTGGAGCTGAAATCTCCGTGCAGGCGCGGAGAGATGATTTTGCTTGCCG
CTCCGGTGGCGGACAGGCAGAGTGCGGCGGTTGAAAGCGGCTGTGCCGGTGACATGCCGGATGGTTTTTCCGGTATGTGC
GCGGGCTTTTTTACGGGCGGTGCGGACGGTACCGGTCTGAAGGCCGGTGCGGTGCTGCATGATGCGTCGCGTCGCGCCGT
GCTGCGTGTGACGGCCAGAGTGCCGCTGGTGCTGCCGTGCATGCAGCATGCGGCATATGGCTATACAGCAACCGTGCTGG
AAGACCTGCCCGCGGGCCGTCTGTCTGCGGCGGTGTGCAGTCCGCAGCTGACCGCCGCATGGGTTACTCTTTCTGACAAA
GGCGCCGCGGGACTGCGTACCGACTCCAGCGGACCGGCCATCGGCGAGATGTTTCGCGGGGCGTTTGCGGATAGCCATGT
GCAGGGGTATCTGCTGCCCGATGAGGGAGCGGCCCTGAAGGCTCTGCTGACCGACCTTGCGCTGACCCAGCGGTACGATG
TCGTTTTCACGACGGGCGGTACGGGGCTGGGCCCCCGTGACGTGACGCCCGAAGCGACGCTGGCCGTCATTGAAAAAAGG
CTGCACGGATTTGAGCAGGCCATGATGGCCGCCAGCCTGTGCAAGACGCCGCATGCGGTGATATCCCGCGCGGTGGCGGG
TACGCTGGGTACCTGCATTATCATTAATATGCCGGGCAGCCGCAAGGCTGTCCTTGAAAACATGCAGGCGGTGCTGCCCG
CTCTTGCTCATGCTTCAGCCAAGCTGCGGGGAGACAAGGCCGACTGCGGAACGTAA

Upstream 100 bases:

>100_bases
TCATGAAGTCCCGCTGCGATGAGCGGTTCTCACATCTGTACCATCGTAAAGGGTGCAAAGACGCTGCGGACGCTTACTAC
CGCATATTGTTTCCCGCATT

Downstream 100 bases:

>100_bases
TCTGAACGTCTCATACGGCGGGGGGGACATATCTTGCCGGTATGAGCTTGTGAGACTGATAATGGATTGTGGAATTCGGG
TCGGGCTTTTTCCTTTGGTG

Product: molybdopterin binding domain-containing protein

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MQRPVQAVTSIAALSAPDRNVRGATRESGMVCTADVDLELKSPCRRGEMILLAAPVADRQSAAVESGCAGDMPDGFSGMC
AGFFTGGADGTGLKAGAVLHDASRRAVLRVTARVPLVLPCMQHAAYGYTATVLEDLPAGRLSAAVCSPQLTAAWVTLSDK
GAAGLRTDSSGPAIGEMFRGAFADSHVQGYLLPDEGAALKALLTDLALTQRYDVVFTTGGTGLGPRDVTPEATLAVIEKR
LHGFEQAMMAASLCKTPHAVISRAVAGTLGTCIIINMPGSRKAVLENMQAVLPALAHASAKLRGDKADCGT

Sequences:

>Translated_311_residues
MQRPVQAVTSIAALSAPDRNVRGATRESGMVCTADVDLELKSPCRRGEMILLAAPVADRQSAAVESGCAGDMPDGFSGMC
AGFFTGGADGTGLKAGAVLHDASRRAVLRVTARVPLVLPCMQHAAYGYTATVLEDLPAGRLSAAVCSPQLTAAWVTLSDK
GAAGLRTDSSGPAIGEMFRGAFADSHVQGYLLPDEGAALKALLTDLALTQRYDVVFTTGGTGLGPRDVTPEATLAVIEKR
LHGFEQAMMAASLCKTPHAVISRAVAGTLGTCIIINMPGSRKAVLENMQAVLPALAHASAKLRGDKADCGT
>Mature_311_residues
MQRPVQAVTSIAALSAPDRNVRGATRESGMVCTADVDLELKSPCRRGEMILLAAPVADRQSAAVESGCAGDMPDGFSGMC
AGFFTGGADGTGLKAGAVLHDASRRAVLRVTARVPLVLPCMQHAAYGYTATVLEDLPAGRLSAAVCSPQLTAAWVTLSDK
GAAGLRTDSSGPAIGEMFRGAFADSHVQGYLLPDEGAALKALLTDLALTQRYDVVFTTGGTGLGPRDVTPEATLAVIEKR
LHGFEQAMMAASLCKTPHAVISRAVAGTLGTCIIINMPGSRKAVLENMQAVLPALAHASAKLRGDKADCGT

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=157, Percent_Identity=39.4904458598726, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI10880983, Length=157, Percent_Identity=39.4904458598726, Blast_Score=105, Evalue=4e-23,
Organism=Escherichia coli, GI1786190, Length=143, Percent_Identity=35.6643356643357, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17564954, Length=154, Percent_Identity=42.8571428571429, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI17136978, Length=156, Percent_Identity=36.5384615384615, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24638841, Length=156, Percent_Identity=36.5384615384615, Blast_Score=102, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 32048; Mature: 32048

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRPVQAVTSIAALSAPDRNVRGATRESGMVCTADVDLELKSPCRRGEMILLAAPVADRQ
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCEEECCCCCCCCEEEEECCCCCCH
SAAVESGCAGDMPDGFSGMCAGFFTGGADGTGLKAGAVLHDASRRAVLRVTARVPLVLPC
HHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCEEHHCCCCEEEEEECCCCHHHHH
MQHAAYGYTATVLEDLPAGRLSAAVCSPQLTAAWVTLSDKGAAGLRTDSSGPAIGEMFRG
HHHHHCCHHHHHHHHCCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
AFADSHVQGYLLPDEGAALKALLTDLALTQRYDVVFTTGGTGLGPRDVTPEATLAVIEKR
HHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHH
LHGFEQAMMAASLCKTPHAVISRAVAGTLGTCIIINMPGSRKAVLENMQAVLPALAHASA
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
KLRGDKADCGT
HCCCCCCCCCC
>Mature Secondary Structure
MQRPVQAVTSIAALSAPDRNVRGATRESGMVCTADVDLELKSPCRRGEMILLAAPVADRQ
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCEEECCCCCCCCEEEEECCCCCCH
SAAVESGCAGDMPDGFSGMCAGFFTGGADGTGLKAGAVLHDASRRAVLRVTARVPLVLPC
HHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCEEHHCCCCEEEEEECCCCHHHHH
MQHAAYGYTATVLEDLPAGRLSAAVCSPQLTAAWVTLSDKGAAGLRTDSSGPAIGEMFRG
HHHHHCCHHHHHHHHCCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
AFADSHVQGYLLPDEGAALKALLTDLALTQRYDVVFTTGGTGLGPRDVTPEATLAVIEKR
HHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHH
LHGFEQAMMAASLCKTPHAVISRAVAGTLGTCIIINMPGSRKAVLENMQAVLPALAHASA
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
KLRGDKADCGT
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]