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The map label for this gene is ttdA [C]

Identifier: 78356302

GI number: 78356302

Start: 1269399

End: 1270238

Strand: Reverse

Name: ttdA [C]

Synonym: Dde_1255

Alternate gene names: 78356302

Gene position: 1270238-1269399 (Counterclockwise)

Preceding gene: 78356303

Following gene: 78356301

Centisome position: 34.05

GC content: 58.93

Gene sequence:

>840_bases
ATGAAAAGCATTAAGGCCGCCGATCTGCACGCCGCCGTGCGTGACATGATTATGGACGCCAACCGTGTGCTGGGAAAAGA
CGTGTACAACGCCTTTCAGACCTGCATGCAGCAAGAGACTACCGACTCCGGCAAGGAGGTACTGCGTCAGCTGCTGGAAA
ACGCCGATCTGGCCGCGCAAAGCGGACTGGCCCTGTGTCAGGACACAGGAGTAGCTGTTTTCTTTGTCGAAATGGGAGAA
GAAGTGCGCATGGAAGGCGGCGGACTGAAAGAAACCCTCAACGCCGCCATGGTGGAAGCCTATAACAAGGCCTTTCTGCG
CAAATCCATGTGCCACCCGCTGACCCGCAAAAACACCGGTGACAACACTCCCGCAGTCATCCACGTGGAACTGGTGCCCG
GGGATACGCTGAAAGTGCGGTACATGGCCAAAGGCGGCGGCAGTGAAAACATGTCGCGCTGTACCATGCTTACCCCCGCA
CAGGGCTGGCAGGGCATCAAGGACTTTGTTGTCCGGCGTATGGCCGAAGCCGGTCCCAACCCCTGCCCCCCCACCATCGT
GGGTGTGGGCATAGGCGGCACGTTCGATCTGGCGCCTTCGCTTGCCAAAGGCGCGCTGTTCCGCCGCGTGGACGATGTGC
ATCCCGACCCGGAAATAGCTGCCATGGAAAAAGAACTGCTGGACGAAATCAATGCGCTGGGCATCGGCCCCATGGGACTG
GGCGGCAAAACCACATGCCTTGCCGTTAAAATAGCCATGCATCCCTGCCACATCGCCAGCCTGCCGCTGGCCGTCAACGT
GCAGTGCCATTCTTCGCGGCACAAGGAGGTTGTATTCTAA

Upstream 100 bases:

>100_bases
CAGCTGGGAATCATGCGCCGCATGCTGGCGCTGAACTCCGTAAAGGGCATTCTGCCCGCTTCCGTGGTGAAAAAACTGCA
AAACCACAAGGGGTGCTGCC

Downstream 100 bases:

>100_bases
TGGCCACCTATTATCTGCAGACCCCCCTGCGCGACCAGGATACCGAACAGCTTAAAGCGGGCGATGTCGTTTTTCTGAAC
GGCGAAATATTCACCGCCCG

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKSIKAADLHAAVRDMIMDANRVLGKDVYNAFQTCMQQETTDSGKEVLRQLLENADLAAQSGLALCQDTGVAVFFVEMGE
EVRMEGGGLKETLNAAMVEAYNKAFLRKSMCHPLTRKNTGDNTPAVIHVELVPGDTLKVRYMAKGGGSENMSRCTMLTPA
QGWQGIKDFVVRRMAEAGPNPCPPTIVGVGIGGTFDLAPSLAKGALFRRVDDVHPDPEIAAMEKELLDEINALGIGPMGL
GGKTTCLAVKIAMHPCHIASLPLAVNVQCHSSRHKEVVF

Sequences:

>Translated_279_residues
MKSIKAADLHAAVRDMIMDANRVLGKDVYNAFQTCMQQETTDSGKEVLRQLLENADLAAQSGLALCQDTGVAVFFVEMGE
EVRMEGGGLKETLNAAMVEAYNKAFLRKSMCHPLTRKNTGDNTPAVIHVELVPGDTLKVRYMAKGGGSENMSRCTMLTPA
QGWQGIKDFVVRRMAEAGPNPCPPTIVGVGIGGTFDLAPSLAKGALFRRVDDVHPDPEIAAMEKELLDEINALGIGPMGL
GGKTTCLAVKIAMHPCHIASLPLAVNVQCHSSRHKEVVF
>Mature_279_residues
MKSIKAADLHAAVRDMIMDANRVLGKDVYNAFQTCMQQETTDSGKEVLRQLLENADLAAQSGLALCQDTGVAVFFVEMGE
EVRMEGGGLKETLNAAMVEAYNKAFLRKSMCHPLTRKNTGDNTPAVIHVELVPGDTLKVRYMAKGGGSENMSRCTMLTPA
QGWQGIKDFVVRRMAEAGPNPCPPTIVGVGIGGTFDLAPSLAKGALFRRVDDVHPDPEIAAMEKELLDEINALGIGPMGL
GGKTTCLAVKIAMHPCHIASLPLAVNVQCHSSRHKEVVF

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=251, Percent_Identity=31.4741035856574, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1790564, Length=262, Percent_Identity=32.824427480916, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787897, Length=262, Percent_Identity=32.824427480916, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 29988; Mature: 29988

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIKAADLHAAVRDMIMDANRVLGKDVYNAFQTCMQQETTDSGKEVLRQLLENADLAAQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHH
SGLALCQDTGVAVFFVEMGEEVRMEGGGLKETLNAAMVEAYNKAFLRKSMCHPLTRKNTG
CCCHHEECCCEEEEEEECCCHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DNTPAVIHVELVPGDTLKVRYMAKGGGSENMSRCTMLTPAQGWQGIKDFVVRRMAEAGPN
CCCCEEEEEEEECCCCEEEEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCC
PCPPTIVGVGIGGTFDLAPSLAKGALFRRVDDVHPDPEIAAMEKELLDEINALGIGPMGL
CCCCCEEEECCCCCHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
GGKTTCLAVKIAMHPCHIASLPLAVNVQCHSSRHKEVVF
CCCCEEEEEEEECCCCHHCCCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MKSIKAADLHAAVRDMIMDANRVLGKDVYNAFQTCMQQETTDSGKEVLRQLLENADLAAQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHH
SGLALCQDTGVAVFFVEMGEEVRMEGGGLKETLNAAMVEAYNKAFLRKSMCHPLTRKNTG
CCCHHEECCCEEEEEEECCCHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DNTPAVIHVELVPGDTLKVRYMAKGGGSENMSRCTMLTPAQGWQGIKDFVVRRMAEAGPN
CCCCEEEEEEEECCCCEEEEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCC
PCPPTIVGVGIGGTFDLAPSLAKGALFRRVDDVHPDPEIAAMEKELLDEINALGIGPMGL
CCCCCEEEECCCCCHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
GGKTTCLAVKIAMHPCHIASLPLAVNVQCHSSRHKEVVF
CCCCEEEEEEEECCCCHHCCCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]