Click here to switch to the map view.

The map label for this gene is tsf

Identifier: 78356179

GI number: 78356179

Start: 1161545

End: 1162141

Strand: Reverse

Name: tsf

Synonym: Dde_1132

Alternate gene names: 78356179

Gene position: 1162141-1161545 (Counterclockwise)

Preceding gene: 78356180

Following gene: 78356178

Centisome position: 31.15

GC content: 55.61

Gene sequence:

>597_bases
ATGGCTGCTATCACTGCCGCAATGGTTAAGGAACTGCGCGAAAAAACCGCCGCAGGTATGATGGACTGCAAGAAAGCCCT
GCAGGAATGCGACGGCGACGAAGCAAAGGCCGTTGACTGGCTGCGCCAGAAGGGTCTTTCCAAGGCCGCCAAAAAGGCCG
ACCGCGCCACCTCCGAAGGGCTGATCGGCTCCTACATCCACTCCAACGGCAAAATCGGCGTCATGGTTGAGCTGAAATGC
GAAACCGACTTCGTGGCACGTAACGAACAGTTCATCGAACTGGCCAAAAACCTGGCCATGCAGATCGCCGCCACCAACCC
CGTGGCCGTGGACGAAAACGGCGTGGATGCAGAACTCATCGAACGCGAACGTGCAGTCTACCGCGAAAAGGCTCTTGCCG
AAGGCAAGCCCGAAAATATCGTGGAAAAGATCGTTGATGGCGCTATCAAGAAGTACTACAAGGAAGTATGCCTTCTTGAA
CAGCCCTTCATCCGTGATGACAAGAAGGTTATCCGCGATCTGCTGAACGACACCATCGCCACTCTGGGCGAAAACATCAC
TGTCGGCCGTTTCTGCCGCTTCCAGCTGGGAGCGTAA

Upstream 100 bases:

>100_bases
CTGAAGAAGCCATGAAGCAGGCTGCCGAAGCTGAAGCCGAAGCTGCTGCTCCCGCTGCCGAAGAATCCGCCGAATAACGA
AGCCCTCAGGAGTTTTTGAT

Downstream 100 bases:

>100_bases
CGGCCGAGTCGGGGTTTTCCCCTGACGGACGACCCGGTTATAAAGGGGGGGCACACAGCCCCCCTTTTTTTGGGCAACGG
CCGGTGGCGCCGCATGACTG

Product: translation elongation factor Ts (EF-Ts)

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MAAITAAMVKELREKTAAGMMDCKKALQECDGDEAKAVDWLRQKGLSKAAKKADRATSEGLIGSYIHSNGKIGVMVELKC
ETDFVARNEQFIELAKNLAMQIAATNPVAVDENGVDAELIERERAVYREKALAEGKPENIVEKIVDGAIKKYYKEVCLLE
QPFIRDDKKVIRDLLNDTIATLGENITVGRFCRFQLGA

Sequences:

>Translated_198_residues
MAAITAAMVKELREKTAAGMMDCKKALQECDGDEAKAVDWLRQKGLSKAAKKADRATSEGLIGSYIHSNGKIGVMVELKC
ETDFVARNEQFIELAKNLAMQIAATNPVAVDENGVDAELIERERAVYREKALAEGKPENIVEKIVDGAIKKYYKEVCLLE
QPFIRDDKKVIRDLLNDTIATLGENITVGRFCRFQLGA
>Mature_197_residues
AAITAAMVKELREKTAAGMMDCKKALQECDGDEAKAVDWLRQKGLSKAAKKADRATSEGLIGSYIHSNGKIGVMVELKCE
TDFVARNEQFIELAKNLAMQIAATNPVAVDENGVDAELIERERAVYREKALAEGKPENIVEKIVDGAIKKYYKEVCLLEQ
PFIRDDKKVIRDLLNDTIATLGENITVGRFCRFQLGA

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI291084500, Length=195, Percent_Identity=30.7692307692308, Blast_Score=80, Evalue=9e-16,
Organism=Homo sapiens, GI291084502, Length=156, Percent_Identity=35.2564102564103, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI171846268, Length=160, Percent_Identity=35.625, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI291084498, Length=103, Percent_Identity=42.7184466019417, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1786366, Length=91, Percent_Identity=51.6483516483517, Blast_Score=94, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17561440, Length=189, Percent_Identity=30.1587301587302, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19921466, Length=123, Percent_Identity=42.2764227642276, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_DESDG (Q313G3)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_387628.1
- ProteinModelPortal:   Q313G3
- SMR:   Q313G3
- STRING:   Q313G3
- GeneID:   3755156
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_1132
- NMPDR:   fig|207559.3.peg.1307
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   MVELSCE
- ProtClustDB:   PRK12332
- BioCyc:   DDES207559:DDE_1132-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 21896; Mature: 21764

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAITAAMVKELREKTAAGMMDCKKALQECDGDEAKAVDWLRQKGLSKAAKKADRATSEG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LIGSYIHSNGKIGVMVELKCETDFVARNEQFIELAKNLAMQIAATNPVAVDENGVDAELI
HHHHHHHCCCCEEEEEEEECCCCHHHCCHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHH
ERERAVYREKALAEGKPENIVEKIVDGAIKKYYKEVCLLEQPFIRDDKKVIRDLLNDTIA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
TLGENITVGRFCRFQLGA
HHCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
AAITAAMVKELREKTAAGMMDCKKALQECDGDEAKAVDWLRQKGLSKAAKKADRATSEG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LIGSYIHSNGKIGVMVELKCETDFVARNEQFIELAKNLAMQIAATNPVAVDENGVDAELI
HHHHHHHCCCCEEEEEEEECCCCHHHCCHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHH
ERERAVYREKALAEGKPENIVEKIVDGAIKKYYKEVCLLEQPFIRDDKKVIRDLLNDTIA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
TLGENITVGRFCRFQLGA
HHCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA