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The map label for this gene is cobQ [H]

Identifier: 78356077

GI number: 78356077

Start: 1055687

End: 1057243

Strand: Direct

Name: cobQ [H]

Synonym: Dde_1030

Alternate gene names: 78356077

Gene position: 1055687-1057243 (Clockwise)

Preceding gene: 78356065

Following gene: 78356080

Centisome position: 28.3

GC content: 61.98

Gene sequence:

>1557_bases
ATGAGCACCTTGGCGCAAAAAACGTTTTCCGTTTCTGTCTCACGCAGCCGCACTCCGGCGCTGATGATTCAGGGCACCTG
CTCCAATGCAGGTAAAAGTATCCTCACTGCGGCCCTGTGCCGTATTCTGCTGCAGGACGGTCTGTCTGTGGCGCCTTTCA
AGTCGCAGAACATGGCACTCAATTCATTTGTGACCCCCGACGGTCTTGAGATCGGGCGCGCTCAGGCCGTTCAGGCGGCG
GCGTGCCGGCTGGAACCTGACGTGCGCATGAATCCGGTGCTGCTCAAACCCAGTTCCGATACGGGGTCTCAGGTCATTGT
CATGGGCAGGCCGGTGGGCAACATGCGGGTGCGCGAATATATGGCCTATAAACCGCAGGCTTTTGCCCGGGCCTGCACTG
CATATGATTCGCTGGCGGACGAACATGACGTGATGGTGCTGGAAGGGGCCGGCAGCCCCGCCGAAATCAACCTGAAGCAG
CACGACATAGTGAACATGGCCATGGCACGCCATGCACAGGCCCGGGTGCTGATTGCCGGTGACATCGACCGCGGCGGAGT
CTTTGCCGCGCTGGTGGGCACATGGGAACTGCTGGACCCTTGGGAACGCGATCTTGTGGCCGGTTTTGTGCTGAACATGT
TCCGCGGTGACGCCTCGCTGCTCGAATCCGCTCTGACGTATGTGACGGAGCGCACCGGCTGCCCGTTTTACGGTGTGGTG
CCGTATGTTTCCGGTCTGGGACTGCCCGAAGAGGATTCCGTTTCCTTCAAAGAGGCTCTGCGCGGTTCCTGTGGCGGCAT
GCCGGAAAGTGTTTGGCCGCACGGAATGCTGGAAGCGGTACTTGTCGACCTGCCGCACATCTCCAACTTTACCGATGTGG
ACGCTTTGCGCGCGGAACCCGACGTGCGCTTGCGGGTGGCAGGTACTGCGGAGGCGCTGGACGCCTGCGGAATGCCGCAT
CTGCTTATTGTTCCCGGCAGTAAGAACACGCTGGCCGATCTGGCAGCGCTGGAAAATAGCGGCATGGGGGCCCGCATCCG
TGCTCTCGCAGGGGCAGGATGTCCCGTGGTAGGCATCTGCGGGGGCTTTCAGATGCTGGGAACATCAGTAACCGACCCGC
ACGGTGTGGAGTCCGGCGCCCGCAGCCGCGAAGGACTGGGGCTGCTGCCTGTGGAAACCGTGATGGGCCGGCATAAAACG
CTGGCCCGCACTGCGGGGCTTCACTGCGATACGGGATGCCGTGTGAGCGGGTACGAGATTCATCACGGAAGCACCACCGC
AAACGGGCCTGTGCGGACAGTGCTGCGCGATGACAGCGGTGCTCCGCTGGGACTGGGCGACACTGACGGTGCGGTTTGGG
GAACCTATCTGCATGGTATTTTTGACGAAGACGATTTCCGCCGCGCGTTTCTGGATGCGCTGCGCCGCCGCGCCGGACTG
GAACCGGTGGGACGGGTGGTGGCCCCATACAGCATTGACGGCGCGCTGGACAGACTGGCGGCCGTGGTCAGGAGCAGCAT
GGATATGACTGCCCTGTACCGTGTGCTGGGATTGTAG

Upstream 100 bases:

>100_bases
CACGGAAATGCGCCATTGTCAATAATAAGCTGCAGCCGCCGCATGCACCGGCAGCCGGAAACGCTGGCAAGCCCCGTGGA
AATGCTGTATCTGCCTTCGG

Downstream 100 bases:

>100_bases
CGGGGCGTTGGTGCCGGAGGCCGCAGCCTGTCTGGGGCAGCCGGTTTGCAGCCGGTTTGCTGCGGGTGCCGGCTCCGGTC
CGGCGGTACCGGCGGGTGCG

Product: cobyric acid synthase

Products: ADP; phosphate; adenosylcobyric acid; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MSTLAQKTFSVSVSRSRTPALMIQGTCSNAGKSILTAALCRILLQDGLSVAPFKSQNMALNSFVTPDGLEIGRAQAVQAA
ACRLEPDVRMNPVLLKPSSDTGSQVIVMGRPVGNMRVREYMAYKPQAFARACTAYDSLADEHDVMVLEGAGSPAEINLKQ
HDIVNMAMARHAQARVLIAGDIDRGGVFAALVGTWELLDPWERDLVAGFVLNMFRGDASLLESALTYVTERTGCPFYGVV
PYVSGLGLPEEDSVSFKEALRGSCGGMPESVWPHGMLEAVLVDLPHISNFTDVDALRAEPDVRLRVAGTAEALDACGMPH
LLIVPGSKNTLADLAALENSGMGARIRALAGAGCPVVGICGGFQMLGTSVTDPHGVESGARSREGLGLLPVETVMGRHKT
LARTAGLHCDTGCRVSGYEIHHGSTTANGPVRTVLRDDSGAPLGLGDTDGAVWGTYLHGIFDEDDFRRAFLDALRRRAGL
EPVGRVVAPYSIDGALDRLAAVVRSSMDMTALYRVLGL

Sequences:

>Translated_518_residues
MSTLAQKTFSVSVSRSRTPALMIQGTCSNAGKSILTAALCRILLQDGLSVAPFKSQNMALNSFVTPDGLEIGRAQAVQAA
ACRLEPDVRMNPVLLKPSSDTGSQVIVMGRPVGNMRVREYMAYKPQAFARACTAYDSLADEHDVMVLEGAGSPAEINLKQ
HDIVNMAMARHAQARVLIAGDIDRGGVFAALVGTWELLDPWERDLVAGFVLNMFRGDASLLESALTYVTERTGCPFYGVV
PYVSGLGLPEEDSVSFKEALRGSCGGMPESVWPHGMLEAVLVDLPHISNFTDVDALRAEPDVRLRVAGTAEALDACGMPH
LLIVPGSKNTLADLAALENSGMGARIRALAGAGCPVVGICGGFQMLGTSVTDPHGVESGARSREGLGLLPVETVMGRHKT
LARTAGLHCDTGCRVSGYEIHHGSTTANGPVRTVLRDDSGAPLGLGDTDGAVWGTYLHGIFDEDDFRRAFLDALRRRAGL
EPVGRVVAPYSIDGALDRLAAVVRSSMDMTALYRVLGL
>Mature_517_residues
STLAQKTFSVSVSRSRTPALMIQGTCSNAGKSILTAALCRILLQDGLSVAPFKSQNMALNSFVTPDGLEIGRAQAVQAAA
CRLEPDVRMNPVLLKPSSDTGSQVIVMGRPVGNMRVREYMAYKPQAFARACTAYDSLADEHDVMVLEGAGSPAEINLKQH
DIVNMAMARHAQARVLIAGDIDRGGVFAALVGTWELLDPWERDLVAGFVLNMFRGDASLLESALTYVTERTGCPFYGVVP
YVSGLGLPEEDSVSFKEALRGSCGGMPESVWPHGMLEAVLVDLPHISNFTDVDALRAEPDVRLRVAGTAEALDACGMPHL
LIVPGSKNTLADLAALENSGMGARIRALAGAGCPVVGICGGFQMLGTSVTDPHGVESGARSREGLGLLPVETVMGRHKTL
ARTAGLHCDTGCRVSGYEIHHGSTTANGPVRTVLRDDSGAPLGLGDTDGAVWGTYLHGIFDEDDFRRAFLDALRRRAGLE
PVGRVVAPYSIDGALDRLAAVVRSSMDMTALYRVLGL

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: 6.3.5.10

Molecular weight: Translated: 54960; Mature: 54828

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLAQKTFSVSVSRSRTPALMIQGTCSNAGKSILTAALCRILLQDGLSVAPFKSQNMAL
CCCHHHHHEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
NSFVTPDGLEIGRAQAVQAAACRLEPDVRMNPVLLKPSSDTGSQVIVMGRPVGNMRVREY
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCHHHHHH
MAYKPQAFARACTAYDSLADEHDVMVLEGAGSPAEINLKQHDIVNMAMARHAQARVLIAG
HHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHCCCEEEEEEE
DIDRGGVFAALVGTWELLDPWERDLVAGFVLNMFRGDASLLESALTYVTERTGCPFYGVV
CCCCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEHH
PYVSGLGLPEEDSVSFKEALRGSCGGMPESVWPHGMLEAVLVDLPHISNFTDVDALRAEP
HHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHCCCC
DVRLRVAGTAEALDACGMPHLLIVPGSKNTLADLAALENSGMGARIRALAGAGCPVVGIC
CEEEEECCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCCEEHHHHCCCCCEEEEC
GGFQMLGTSVTDPHGVESGARSREGLGLLPVETVMGRHKTLARTAGLHCDTGCRVSGYEI
CCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHCCCCCCCCCEECCEEE
HHGSTTANGPVRTVLRDDSGAPLGLGDTDGAVWGTYLHGIFDEDDFRRAFLDALRRRAGL
ECCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
EPVGRVVAPYSIDGALDRLAAVVRSSMDMTALYRVLGL
CCHHHEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure 
STLAQKTFSVSVSRSRTPALMIQGTCSNAGKSILTAALCRILLQDGLSVAPFKSQNMAL
CCHHHHHEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
NSFVTPDGLEIGRAQAVQAAACRLEPDVRMNPVLLKPSSDTGSQVIVMGRPVGNMRVREY
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCHHHHHH
MAYKPQAFARACTAYDSLADEHDVMVLEGAGSPAEINLKQHDIVNMAMARHAQARVLIAG
HHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHCCCEEEEEEE
DIDRGGVFAALVGTWELLDPWERDLVAGFVLNMFRGDASLLESALTYVTERTGCPFYGVV
CCCCCCEEEEEHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEHH
PYVSGLGLPEEDSVSFKEALRGSCGGMPESVWPHGMLEAVLVDLPHISNFTDVDALRAEP
HHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHCCCC
DVRLRVAGTAEALDACGMPHLLIVPGSKNTLADLAALENSGMGARIRALAGAGCPVVGIC
CEEEEECCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCCEEHHHHCCCCCEEEEC
GGFQMLGTSVTDPHGVESGARSREGLGLLPVETVMGRHKTLARTAGLHCDTGCRVSGYEI
CCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHCCCCCCCCCEECCEEE
HHGSTTANGPVRTVLRDDSGAPLGLGDTDGAVWGTYLHGIFDEDDFRRAFLDALRRRAGL
ECCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
EPVGRVVAPYSIDGALDRLAAVVRSSMDMTALYRVLGL
CCHHHEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; adenosylcobyrinic acid a,c-diamide; L-glutamine; H2O

Specific reaction: 4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H2O = 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA