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The map label for this gene is xerC [H]

Identifier: 78355959

GI number: 78355959

Start: 939853

End: 940767

Strand: Reverse

Name: xerC [H]

Synonym: Dde_0912

Alternate gene names: 78355959

Gene position: 940767-939853 (Counterclockwise)

Preceding gene: 78355960

Following gene: 78355955

Centisome position: 25.22

GC content: 67.54

Gene sequence:

>915_bases
ATGAGCAACCGAACGGCTGACCTCGACCTGACGGGCGCGACAGAGGCGTTCTGTGCCCGCCTGTCGGCCGAAGGACGCTC
CCCGGCGACCATAGCCGCATACCGCCGGGACCTTGCCCTGGTGGCCCGCGTTGCCGATGAGCTGGCCCCGGGCATCATCT
GCCGGGCGATCACGGCCGGGCTCCTCGACCGGGCGTTCTCCGCCGGGGCGGTCACCGAGAGCGGGCGCGGCCCACGCTCG
GCGGCCTCGCTCCATCGGATGAAGGCGGCGGTGCGGGCCTTTTTCGCCTGGGCCTCCGAGGCTGGCGTGGTCGATGACAA
TCCGGCCCGGTCCATCCGCATGCATCGGCTGCCGAGAAAGCTGCCGGTGTTCCTGACCACCGCCGAAAAGAAACGACTGC
TCAAGGAACTCAAGGGACGGACCGACTTCTCCGCTCTGCGCGACCGCGCCATGATCGAGGTGCTGCTGGGCACCGGGATC
AGGCTTGGCGAGCTGGCCGCGCTCGACATGGATGACATCGACCTCGACGCCAAACATCTGCGGGTGCGGGCCAAGGGGAA
TGTACCGCAGGTCAAGTTCATCAAGACCGACCTCCGCACATTGCTGCGCCGTTACCTGGCCGAGCGCCGCCGACATGGCC
GTCCGGAAATGGAAGCCCTGTTCCTGTCGAACCGGGACGGCAGACTCTGCCAGCGGCAGATTGCCAACCGGCTCGCCCAC
TGGCTGCGGAAGGCCGGGATCGAAAAGGAACTGACGCCGCACGGGCTGCGGCATACCTTCGCCACCCACCTCTACGGCGC
GACCAATGACCTGCTCGTGGTGCAGCGGGCCTTGGGGCATCGGGACGTGTCCACCACCCAGATCTACACCCACCTCGTGG
ACGGCCAGCTCGAGGAAGCCCTCGAACGCCTCTGA

Upstream 100 bases:

>100_bases
CGCATGATGATGGTATGGGCCAGGGAATCGGGGCGCATCGAGGAGCTGCCGCTGCCCAAGAGCACACCCATGGGTCACAG
CAGGGTGAAGGAGTCCAGCG

Downstream 100 bases:

>100_bases
TCCTTCCGGACCCGACGATGGGAGCGGCCTCGGCTGCTCCTGTTTTCGTTGGGGAAGACAGTATCGAAGACAGTGAATGA
CAGTGCCCGCAGAAGAACAC

Product: integrase/recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSNRTADLDLTGATEAFCARLSAEGRSPATIAAYRRDLALVARVADELAPGIICRAITAGLLDRAFSAGAVTESGRGPRS
AASLHRMKAAVRAFFAWASEAGVVDDNPARSIRMHRLPRKLPVFLTTAEKKRLLKELKGRTDFSALRDRAMIEVLLGTGI
RLGELAALDMDDIDLDAKHLRVRAKGNVPQVKFIKTDLRTLLRRYLAERRRHGRPEMEALFLSNRDGRLCQRQIANRLAH
WLRKAGIEKELTPHGLRHTFATHLYGATNDLLVVQRALGHRDVSTTQIYTHLVDGQLEEALERL

Sequences:

>Translated_304_residues
MSNRTADLDLTGATEAFCARLSAEGRSPATIAAYRRDLALVARVADELAPGIICRAITAGLLDRAFSAGAVTESGRGPRS
AASLHRMKAAVRAFFAWASEAGVVDDNPARSIRMHRLPRKLPVFLTTAEKKRLLKELKGRTDFSALRDRAMIEVLLGTGI
RLGELAALDMDDIDLDAKHLRVRAKGNVPQVKFIKTDLRTLLRRYLAERRRHGRPEMEALFLSNRDGRLCQRQIANRLAH
WLRKAGIEKELTPHGLRHTFATHLYGATNDLLVVQRALGHRDVSTTQIYTHLVDGQLEEALERL
>Mature_303_residues
SNRTADLDLTGATEAFCARLSAEGRSPATIAAYRRDLALVARVADELAPGIICRAITAGLLDRAFSAGAVTESGRGPRSA
ASLHRMKAAVRAFFAWASEAGVVDDNPARSIRMHRLPRKLPVFLTTAEKKRLLKELKGRTDFSALRDRAMIEVLLGTGIR
LGELAALDMDDIDLDAKHLRVRAKGNVPQVKFIKTDLRTLLRRYLAERRRHGRPEMEALFLSNRDGRLCQRQIANRLAHW
LRKAGIEKELTPHGLRHTFATHLYGATNDLLVVQRALGHRDVSTTQIYTHLVDGQLEEALERL

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerD binding sites by a short central region, forming

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=285, Percent_Identity=35.7894736842105, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1789261, Length=277, Percent_Identity=35.3790613718412, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1790767, Length=169, Percent_Identity=29.585798816568, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33865; Mature: 33733

Theoretical pI: Translated: 10.89; Mature: 10.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRTADLDLTGATEAFCARLSAEGRSPATIAAYRRDLALVARVADELAPGIICRAITAG
CCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLDRAFSAGAVTESGRGPRSAASLHRMKAAVRAFFAWASEAGVVDDNPARSIRMHRLPRK
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
LPVFLTTAEKKRLLKELKGRTDFSALRDRAMIEVLLGTGIRLGELAALDMDDIDLDAKHL
CCEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCHHHE
RVRAKGNVPQVKFIKTDLRTLLRRYLAERRRHGRPEMEALFLSNRDGRLCQRQIANRLAH
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCCHHHHHHHHHHHHH
WLRKAGIEKELTPHGLRHTFATHLYGATNDLLVVQRALGHRDVSTTQIYTHLVDGQLEEA
HHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LERL
HHCC
>Mature Secondary Structure 
SNRTADLDLTGATEAFCARLSAEGRSPATIAAYRRDLALVARVADELAPGIICRAITAG
CCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLDRAFSAGAVTESGRGPRSAASLHRMKAAVRAFFAWASEAGVVDDNPARSIRMHRLPRK
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
LPVFLTTAEKKRLLKELKGRTDFSALRDRAMIEVLLGTGIRLGELAALDMDDIDLDAKHL
CCEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCHHHE
RVRAKGNVPQVKFIKTDLRTLLRRYLAERRRHGRPEMEALFLSNRDGRLCQRQIANRLAH
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEECCCCCHHHHHHHHHHHHH
WLRKAGIEKELTPHGLRHTFATHLYGATNDLLVVQRALGHRDVSTTQIYTHLVDGQLEEA
HHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LERL
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]