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The map label for this gene is cvrA [H]

Identifier: 78355915

GI number: 78355915

Start: 896617

End: 898437

Strand: Reverse

Name: cvrA [H]

Synonym: Dde_0868

Alternate gene names: 78355915

Gene position: 898437-896617 (Counterclockwise)

Preceding gene: 78355916

Following gene: 78355912

Centisome position: 24.09

GC content: 57.17

Gene sequence:

>1821_bases
ATGCACGCTTCAACACTGGTCCTGATCATACTGTGCGCCGGACTGGCCAGCCAGTGGCTGGCATGGCGGCTTCGCCTGCC
TGCGGTTGTCGTTCTGATCACCACGGGCATTATGCTTGGTCCTGCAAGCGGCATCATTGATCCGGGTCTGTCGCAGGCGG
AACTGACGGAACTCATCGGTCTGGGGGTCGCCATTATTCTATTTGAAGGCGGCATGGACCTGAAACTGGGCGAGATCCGG
CGCGTCGGTCATGGCGTGGGGCGGCTGACAATTTTAGGGCCTCCGCTGGCCTGGATTTTCGGTGCACTGGCTGCCCGCTT
TGTTGCCGGACTCAGCTGGCCGGTATCATGGGTGCTGGGCGCCATTCTGGTTGTTACCGGCCCCACTGTAATCCTGCCCT
TGCTGCGGCAGGCCCATCTCAACAAAAGGTCTGCGGCACTGCTGAAATGGGAAGGCATTGCCAACGATCCCGTGGGCGTT
TTACTGGCAGTACTTACTTTTCAGTATTTTACGCTTACTGATGGCGGATGGACACAGGTGCTTGCGGGACTGGCTTCGGC
TGCGGCCATGGCAGGACTGCTTGGCGGGCTGGGAGGCTGGCTCATCGGCTGGCTTTACCGCCGGGGAGTCGTCCCGACAC
GCCTTAAGGCGCCTCTGCTGATGGTACTGGTGCTGGCCGCATACTGGGCAAGCAATCTCATCCAGCATGAAGCGGGTCTC
CTTACTGTGACTGTGATGGGAGTGGTCATCGGCAATATGCAGCTTGTGGAACGTGAGCCACTGCGACATTTCAAAGAAAA
CCTCACCATTGTACTGCTGTCCGCTCTGTTTATCGTCATTCCTTCACAGCTTCATCTGGAACAGGTGAACCTGCTTAACT
GGCCTGTGGCCGCCTTTGTACTGGTCACCCTGCTTGTTGTGCGCCCGCTGTCAATCGTGCTGGCTACCGTTGGTGCCCCC
ATGCGCGGCGAGGACAAGCTGTTGCTGGCATGGATTGCTCCCCGCGGAATCGTTGCCGCAGCCACTGCAGGAATTTTCGG
ACCGGCGCTGGTAGCCGCCGGATATCAGGATGCCGAAGCACTTCTGCCCATTGTCTTTCTGATCATTTTTACCACCGTGC
TGGCACATGGGTTCACGCTGGGACCACTGGCGCGAAAACTGGGGCTGGCAGCGGAAGAAGAAAACGGCCTGCTCATTGTA
GGCGCCTCTCCCTGGTCACGGACTCTGGCTCAGGCTCTGAAAAAGCTTGATGCGGATGTGGTAGTGGCCGACGGCTCCTA
CCAGCGGCTCAGACCTTTCCGGATGGACGGCATAAAGGTGTATTACGGTGAAATTCTTTCTGAACATGCCGAGCATGAAC
TCGATGACGAACACCTGAGCTATCTGCTCTGCGCAACCGACAACCATTACTACAACGCGCTGGTCTGCAAGGCACAGGGG
CACGAATTCGGCCATCACCGCACCTTTCAGCTGGCCCCCTGCCAGGAAGCCGGACATGAACAAAAACGGCTTCTTTTGCA
GCAACGCGGCTACTTTGCCTTTGAACCGCCAACAGATTTTTGCACATTGCACCAGCTGTTAAGCGACGGCTGGACAGTAC
AGTCCACCCGCCTGAGCGACACTTTCAATATCGGCAGGCTGAAAGACAGACTCGGCGCTCCCGGTGCCGACTGGATATTG
ATCGGCGGAGTATCCCCGCAGGGAAAACTGCAGATTTATTCCAATGAACAGGCATTCAAGCCTGCCAAGGGCTGGACGCT
GCTTTACTTTGCACCCGAGAAAAAAGAGGCAGCACAAGCCAGAAGTGACACAGAACAGTGA

Upstream 100 bases:

>100_bases
CGTTGCTGATGCGGAACACAGCACCTTCCCCCGGACAGAGGCTGAAACAACTTGGCAGTTCTTCGGGCTTTTGGGGCGGT
AACTAACATATGGAGATCTC

Downstream 100 bases:

>100_bases
TGCGCAGGATAGTGCTGCAGCCGGATGACAACGTATTCCCCGTATCCGCGAGAGATGTCGCCGGTATTCAGCTTGCCGGT
GTCCGGTTTGCCGCTTCTTC

Product: Na(+):H(+) antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 606; Mature: 606

Protein sequence:

>606_residues
MHASTLVLIILCAGLASQWLAWRLRLPAVVVLITTGIMLGPASGIIDPGLSQAELTELIGLGVAIILFEGGMDLKLGEIR
RVGHGVGRLTILGPPLAWIFGALAARFVAGLSWPVSWVLGAILVVTGPTVILPLLRQAHLNKRSAALLKWEGIANDPVGV
LLAVLTFQYFTLTDGGWTQVLAGLASAAAMAGLLGGLGGWLIGWLYRRGVVPTRLKAPLLMVLVLAAYWASNLIQHEAGL
LTVTVMGVVIGNMQLVEREPLRHFKENLTIVLLSALFIVIPSQLHLEQVNLLNWPVAAFVLVTLLVVRPLSIVLATVGAP
MRGEDKLLLAWIAPRGIVAAATAGIFGPALVAAGYQDAEALLPIVFLIIFTTVLAHGFTLGPLARKLGLAAEEENGLLIV
GASPWSRTLAQALKKLDADVVVADGSYQRLRPFRMDGIKVYYGEILSEHAEHELDDEHLSYLLCATDNHYYNALVCKAQG
HEFGHHRTFQLAPCQEAGHEQKRLLLQQRGYFAFEPPTDFCTLHQLLSDGWTVQSTRLSDTFNIGRLKDRLGAPGADWIL
IGGVSPQGKLQIYSNEQAFKPAKGWTLLYFAPEKKEAAQARSDTEQ

Sequences:

>Translated_606_residues
MHASTLVLIILCAGLASQWLAWRLRLPAVVVLITTGIMLGPASGIIDPGLSQAELTELIGLGVAIILFEGGMDLKLGEIR
RVGHGVGRLTILGPPLAWIFGALAARFVAGLSWPVSWVLGAILVVTGPTVILPLLRQAHLNKRSAALLKWEGIANDPVGV
LLAVLTFQYFTLTDGGWTQVLAGLASAAAMAGLLGGLGGWLIGWLYRRGVVPTRLKAPLLMVLVLAAYWASNLIQHEAGL
LTVTVMGVVIGNMQLVEREPLRHFKENLTIVLLSALFIVIPSQLHLEQVNLLNWPVAAFVLVTLLVVRPLSIVLATVGAP
MRGEDKLLLAWIAPRGIVAAATAGIFGPALVAAGYQDAEALLPIVFLIIFTTVLAHGFTLGPLARKLGLAAEEENGLLIV
GASPWSRTLAQALKKLDADVVVADGSYQRLRPFRMDGIKVYYGEILSEHAEHELDDEHLSYLLCATDNHYYNALVCKAQG
HEFGHHRTFQLAPCQEAGHEQKRLLLQQRGYFAFEPPTDFCTLHQLLSDGWTVQSTRLSDTFNIGRLKDRLGAPGADWIL
IGGVSPQGKLQIYSNEQAFKPAKGWTLLYFAPEKKEAAQARSDTEQ
>Mature_606_residues
MHASTLVLIILCAGLASQWLAWRLRLPAVVVLITTGIMLGPASGIIDPGLSQAELTELIGLGVAIILFEGGMDLKLGEIR
RVGHGVGRLTILGPPLAWIFGALAARFVAGLSWPVSWVLGAILVVTGPTVILPLLRQAHLNKRSAALLKWEGIANDPVGV
LLAVLTFQYFTLTDGGWTQVLAGLASAAAMAGLLGGLGGWLIGWLYRRGVVPTRLKAPLLMVLVLAAYWASNLIQHEAGL
LTVTVMGVVIGNMQLVEREPLRHFKENLTIVLLSALFIVIPSQLHLEQVNLLNWPVAAFVLVTLLVVRPLSIVLATVGAP
MRGEDKLLLAWIAPRGIVAAATAGIFGPALVAAGYQDAEALLPIVFLIIFTTVLAHGFTLGPLARKLGLAAEEENGLLIV
GASPWSRTLAQALKKLDADVVVADGSYQRLRPFRMDGIKVYYGEILSEHAEHELDDEHLSYLLCATDNHYYNALVCKAQG
HEFGHHRTFQLAPCQEAGHEQKRLLLQQRGYFAFEPPTDFCTLHQLLSDGWTVQSTRLSDTFNIGRLKDRLGAPGADWIL
IGGVSPQGKLQIYSNEQAFKPAKGWTLLYFAPEKKEAAQARSDTEQ

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 65599; Mature: 65599

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHASTLVLIILCAGLASQWLAWRLRLPAVVVLITTGIMLGPASGIIDPGLSQAELTELIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
LGVAIILFEGGMDLKLGEIRRVGHGVGRLTILGPPLAWIFGALAARFVAGLSWPVSWVLG
CCEEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHH
AILVVTGPTVILPLLRQAHLNKRSAALLKWEGIANDPVGVLLAVLTFQYFTLTDGGWTQV
HHHHHCCHHHHHHHHHHHHCCCHHCEEEEECCCCCCHHHHHHHHHHHHHEEECCCCHHHH
LAGLASAAAMAGLLGGLGGWLIGWLYRRGVVPTRLKAPLLMVLVLAAYWASNLIQHEAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
LTVTVMGVVIGNMQLVEREPLRHFKENLTIVLLSALFIVIPSQLHLEQVNLLNWPVAAFV
HHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHH
LVTLLVVRPLSIVLATVGAPMRGEDKLLLAWIAPRGIVAAATAGIFGPALVAAGYQDAEA
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHH
LLPIVFLIIFTTVLAHGFTLGPLARKLGLAAEEENGLLIVGASPWSRTLAQALKKLDADV
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEECCCCEEEEECCCHHHHHHHHHHHCCCCE
VVADGSYQRLRPFRMDGIKVYYGEILSEHAEHELDDEHLSYLLCATDNHYYNALVCKAQG
EEECCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHEEEEEECCCCEEEEEEEEECC
HEFGHHRTFQLAPCQEAGHEQKRLLLQQRGYFAFEPPTDFCTLHQLLSDGWTVQSTRLSD
CCCCCCCEEEECCCHHCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCEEEEEECCC
TFNIGRLKDRLGAPGADWILIGGVSPQGKLQIYSNEQAFKPAKGWTLLYFAPEKKEAAQA
CCCHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCEEEEECCCHHHHHHH
RSDTEQ
HCCCCC
>Mature Secondary Structure
MHASTLVLIILCAGLASQWLAWRLRLPAVVVLITTGIMLGPASGIIDPGLSQAELTELIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
LGVAIILFEGGMDLKLGEIRRVGHGVGRLTILGPPLAWIFGALAARFVAGLSWPVSWVLG
CCEEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHH
AILVVTGPTVILPLLRQAHLNKRSAALLKWEGIANDPVGVLLAVLTFQYFTLTDGGWTQV
HHHHHCCHHHHHHHHHHHHCCCHHCEEEEECCCCCCHHHHHHHHHHHHHEEECCCCHHHH
LAGLASAAAMAGLLGGLGGWLIGWLYRRGVVPTRLKAPLLMVLVLAAYWASNLIQHEAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
LTVTVMGVVIGNMQLVEREPLRHFKENLTIVLLSALFIVIPSQLHLEQVNLLNWPVAAFV
HHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHH
LVTLLVVRPLSIVLATVGAPMRGEDKLLLAWIAPRGIVAAATAGIFGPALVAAGYQDAEA
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHH
LLPIVFLIIFTTVLAHGFTLGPLARKLGLAAEEENGLLIVGASPWSRTLAQALKKLDADV
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEECCCCEEEEECCCHHHHHHHHHHHCCCCE
VVADGSYQRLRPFRMDGIKVYYGEILSEHAEHELDDEHLSYLLCATDNHYYNALVCKAQG
EEECCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHEEEEEECCCCEEEEEEEEECC
HEFGHHRTFQLAPCQEAGHEQKRLLLQQRGYFAFEPPTDFCTLHQLLSDGWTVQSTRLSD
CCCCCCCEEEECCCHHCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCEEEEEECCC
TFNIGRLKDRLGAPGADWILIGGVSPQGKLQIYSNEQAFKPAKGWTLLYFAPEKKEAAQA
CCCHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCEEEEECCCHHHHHHH
RSDTEQ
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA