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The map label for this gene is sstT [H]

Identifier: 78355855

GI number: 78355855

Start: 827997

End: 829226

Strand: Reverse

Name: sstT [H]

Synonym: Dde_0808

Alternate gene names: 78355855

Gene position: 829226-827997 (Counterclockwise)

Preceding gene: 78355856

Following gene: 78355854

Centisome position: 22.23

GC content: 58.37

Gene sequence:

>1230_bases
TTGAAGGGGCGGCGGCTCCTTACACCATCGGAGGAGACTATCATATCCAGACGCAAAAGCGAATTCGGCCTCATCATCAA
GCTGCTGGCGGGCATCGCCATCGGCGCAGGCATCGGGTTCATGGCTGACGAAACAGTCATGCAGATCATCATGTCCGTCA
AGCATGTGCTCGGGCAGCTCATCTTTTACACGGTTCCGCTTGTCATCATCGCATTCATCGCTCCTGCCATCACCCGTCTG
GGTGAAAACGCCAGCCGCATGCTGATGACCGGTGTGGGCATTGCCTACATGTCGTCTGTGGGCGCGGCCACCATGGCCTG
TCTGGCAGGCTATGCCATTATTCCGCACCTTTCCGTACCTACATCGGTCGAAGGTCTGCGCGAACTTCCCAAAATACTCT
TCCAGCTTAATATTCCGGCAATCATGCCTGTCATGACAGCACTCATCACCGCCATCATGCTGGGTATAGCCACCCTGTGG
ACCCGTGCGGAAGTCATGGGCAAGCTGCTGGGTGAACTGGAAAAAATAATGATGCAGGTTGTCAGCCGCGTCGTTATTCC
CATTCTGCCTTTCTTCATTGCCACCACCTTTGCCGGCCTTGCCTACGAAGGCAGCCTCACACGGCAGCTGCCGGTATTCC
TCAAGGTCATCGTACTGGTGCTGCTGGGCCATTTCATCTGGCTGGCCGTCATGTACACCATTGCGGGCATTGTTTCGCGC
CGCAACCCCATCGAGGTGCTGCGCCACTACCCGCCCGCCTATCTGACCGCCGTGGGCACCATGTCCAGCGCCGCCACACT
GCCCGTGGCACTGGAATGCGCATCGCGTTCACGGGTGCTTTCCAAAGACACGGTTGAATTTGCCGTGCCGCTGGGCGCCA
CCATCCACCTGTGCGGTTCAGTACTTACCGAAACCTTCTTCGCCATGACCATCTCGCTGATGCTGTACGGCCACATGCCC
GCTTTCGGCACCATGTTCGTGTTCATCATCCTGTTCGGCGTATTCGCCATCGGCGCTCCGGGCGTGCCCGGCGGCACGGT
CATGGCTTCGCTGGGCATTGTGGTGGGCGTGCTGGGATTCGACCCCGCGGGCGTTGCCCTGCTACTTGCCATCTTTGCTC
TGCAGGACAGCTTCGGCACGGCATGCAACGTAACCGGCGACGGTGCCATTGCCCTGATGCTCGAAGGCATATTCAACAGA
AACGGAGAGCTTTCGGGGCACAAGCTATAG

Upstream 100 bases:

>100_bases
CGTTCAGGTTGCTGCCCTGCCGCTGGGCGCGGGAGTGGAAATAGAAGTGGTTGCGCGCCGGTAATTCAGGGGGAAGCCGG
ACTGTCCCGGGAAGCCGCCG

Downstream 100 bases:

>100_bases
GCACGTTCCGCCGCATCTCCATGACAACGCCATAGAAACGGATATATATATGCTCAAACCGGAATGGTCCCGATATATAG
ACCTGCTGCACAAGGAAGTT

Product: serine/threonine sodium symporter

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MKGRRLLTPSEETIISRRKSEFGLIIKLLAGIAIGAGIGFMADETVMQIIMSVKHVLGQLIFYTVPLVIIAFIAPAITRL
GENASRMLMTGVGIAYMSSVGAATMACLAGYAIIPHLSVPTSVEGLRELPKILFQLNIPAIMPVMTALITAIMLGIATLW
TRAEVMGKLLGELEKIMMQVVSRVVIPILPFFIATTFAGLAYEGSLTRQLPVFLKVIVLVLLGHFIWLAVMYTIAGIVSR
RNPIEVLRHYPPAYLTAVGTMSSAATLPVALECASRSRVLSKDTVEFAVPLGATIHLCGSVLTETFFAMTISLMLYGHMP
AFGTMFVFIILFGVFAIGAPGVPGGTVMASLGIVVGVLGFDPAGVALLLAIFALQDSFGTACNVTGDGAIALMLEGIFNR
NGELSGHKL

Sequences:

>Translated_409_residues
MKGRRLLTPSEETIISRRKSEFGLIIKLLAGIAIGAGIGFMADETVMQIIMSVKHVLGQLIFYTVPLVIIAFIAPAITRL
GENASRMLMTGVGIAYMSSVGAATMACLAGYAIIPHLSVPTSVEGLRELPKILFQLNIPAIMPVMTALITAIMLGIATLW
TRAEVMGKLLGELEKIMMQVVSRVVIPILPFFIATTFAGLAYEGSLTRQLPVFLKVIVLVLLGHFIWLAVMYTIAGIVSR
RNPIEVLRHYPPAYLTAVGTMSSAATLPVALECASRSRVLSKDTVEFAVPLGATIHLCGSVLTETFFAMTISLMLYGHMP
AFGTMFVFIILFGVFAIGAPGVPGGTVMASLGIVVGVLGFDPAGVALLLAIFALQDSFGTACNVTGDGAIALMLEGIFNR
NGELSGHKL
>Mature_409_residues
MKGRRLLTPSEETIISRRKSEFGLIIKLLAGIAIGAGIGFMADETVMQIIMSVKHVLGQLIFYTVPLVIIAFIAPAITRL
GENASRMLMTGVGIAYMSSVGAATMACLAGYAIIPHLSVPTSVEGLRELPKILFQLNIPAIMPVMTALITAIMLGIATLW
TRAEVMGKLLGELEKIMMQVVSRVVIPILPFFIATTFAGLAYEGSLTRQLPVFLKVIVLVLLGHFIWLAVMYTIAGIVSR
RNPIEVLRHYPPAYLTAVGTMSSAATLPVALECASRSRVLSKDTVEFAVPLGATIHLCGSVLTETFFAMTISLMLYGHMP
AFGTMFVFIILFGVFAIGAPGVPGGTVMASLGIVVGVLGFDPAGVALLLAIFALQDSFGTACNVTGDGAIALMLEGIFNR
NGELSGHKL

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI223468566, Length=192, Percent_Identity=30.7291666666667, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI223468564, Length=192, Percent_Identity=30.7291666666667, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI169790839, Length=259, Percent_Identity=27.4131274131274, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI66773030, Length=235, Percent_Identity=28.936170212766, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI5032093, Length=187, Percent_Identity=30.4812834224599, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI40254478, Length=228, Percent_Identity=29.8245614035088, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI194239697, Length=235, Percent_Identity=29.7872340425532, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI21314632, Length=307, Percent_Identity=24.7557003257329, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4827012, Length=253, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71996953, Length=247, Percent_Identity=27.5303643724696, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71983099, Length=243, Percent_Identity=27.9835390946502, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71983106, Length=243, Percent_Identity=27.9835390946502, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17537407, Length=254, Percent_Identity=28.740157480315, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193206505, Length=164, Percent_Identity=28.0487804878049, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583025, Length=198, Percent_Identity=30.3030303030303, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17137668, Length=198, Percent_Identity=30.3030303030303, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24583023, Length=198, Percent_Identity=30.3030303030303, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR023025 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 43488; Mature: 43488

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure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CHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]