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The map label for this gene is atoS [H]

Identifier: 78355605

GI number: 78355605

Start: 580453

End: 582744

Strand: Reverse

Name: atoS [H]

Synonym: Dde_0558

Alternate gene names: 78355605

Gene position: 582744-580453 (Counterclockwise)

Preceding gene: 78355606

Following gene: 78355602

Centisome position: 15.62

GC content: 56.85

Gene sequence:

>2292_bases
ATGCCACCCAGAATAACACTTGCCCCGACCCCGAAGCAGTTCGTGGGACGCAGTATTTCCCGCGATCTGACCATCAGCCT
GCTTGTCATGCTTATGGTCGTGGTGGGGGGCATGGCGTCCATACAGTACATCAGCCACTCGCGCACGTCGCTGGAAGAGC
TGGACAACAAGGCCGATGAATATATCACGCGCCTGGCCGACATACTCTCGGTTCCCATATGGAATTTCGACACCCGTACC
ATCGAACAGATCGGCAGTGTGTTCACCCAGTACGATCTGGTCAACGAAGTGGTCATCAAAGACCCGGCGGGACACACGCT
GTTTTCTGTCACCAAAGCCCCCGATCCCGACGCCACACTCATCCGCCAGCGTGATATTTTTTATGACGGTGAAATAATCG
GCAACGTGCGGGTGGTGCTGACCCTGCGCGAATACAAAAGAAGCCTGCGCCGCATGCTTTCCACCACGGCGCTGACCATC
GGCGGGGTTGCGCTGGTCATTGTGCTGGCAACGGGTGTTCTGCTGCGTATTTATCTGCGCCGCCCGCTTGATGTGCTCTT
GTCCAGCATAGACAAAGTTTCAAAGGGTGATTTCCGCCACGACTTCAGCACCATACAGCAGGCCGAACTGGCAGCCATAG
CCCGCAGCTTTGCCAGCATGAGCGCAAAGGTTGAAGCGCGCGAAAAAGCCCTGCAGCGCATGAACAGCCAGCTGCAGGAA
GAAGTGGCCGAACGTGAGCGGGCAGAGCAGGCGCTGCGCAACAGCGAAGAACGGTATTCTCTGGCCGTCGGCGGCACCAA
CGACGGCATATGGGACTGGGATCTGATCTCGAATAAAGTGTATTTTTCACCCCGCTGGAAGGAAATCATCGGTTTTCAGG
ACCACGAAATACCCAACGAGATTCCCGAGTGGACCAGCCGCGTGCACCCTGATGATCTGGCCAAGATACTCAAGGCGCAC
GAAATGTATCTTTCACGCGAACTGCCCGCTTTTGAAGTGGAATACAGGCTGCGGCACAAAGACGGCAGCTACCGCTGGAT
TCTGGGACGCGGGCTGGCGCTGTGGAGCGACGCCGACCAGCCGTACCGCATGGCCGGTGCACATACCGACATCACCGACA
GAAAAGAATCGGAACGCGAACTGCTGGCCACCAAAAACCGGCTGGACAACATTCTCAATTCCATGCCGTCGCTCATCGTG
GGCGTCAGCGACAACGGCATCATTCTGCAATGGAACCGCACGGCGGAAGAGGAAACCTCCGTTTCCGCCCGCGATGCCAT
CGGCACGCCTTTTGAGAACACGCTGCCTGAATTCTCTTTTCTCATGGGCAAGGTGCTTCAGTCGCTCAATTCCGGCGAAA
CCATATCACTGGAACGCAAAGCCATCACCTACAGCGACCGTGTGCGCACGTTTGACATCATAATCTACCCCGTGACCGAA
CGCGGCGAACACAGCGCAGTCATACGCATTGACGATGTGACAGACCGCATCCGCATTGAAGAGATGATGGTACAGACAGA
AAAAATGATGTCCGTGGGCGGACTGGCGGCGGGTATGGCGCACGAAATCAACAACCCGCTGGGGGGCATTCTGCAGGGGG
CGCAAAATATCGTACGGCGCATCTCCACAGAGATAAAAGCGAACCATGCCGCTGCGGACGAAGTGGGCTGCGACCTGACG
GCCATACGGGCCTATATGGAAAAACGCGGCATCACCCGGTTCCTTGACGGCATTCAGGAATCGGGCAACCGTGCGGCAAA
AATAGTTTCCAACATGCTGGAGTTCAGCCGCCGCAGCGAGTCGCGCAGACAGCTGGCCGACATGCATGCCCTGATGGACA
AAACAGTGGAACTGGCCGCCAACGACTATGATCTGAAAAAGAAATATGACTTCAGGCACATAGAACTTGTCCGCGATTAT
GCCCCCGACCTGCCCGGCATACACTGCACCCCGACGGAAATAGAGCAGGTGCTGCTGAACCTGCTGAAAAATTCGGCACA
AGCCATGGCAGGCAGGCCCAAAGACAGCACCGAACCGCCGCGCATCACCCTGCGCACCCGCCTGCAACACGACAAGGTGT
GCATTCAGGTGCTCGATAACGGTCCCGGTATGGACGAAGAAACCCGCAAGCGGGTTTTTGAACCCTTCTTCACCACCAAA
AGTGTGGGAGAAGGTACCGGACTGGGGCTTTCGGTCTCGTACTTCATTATCACCACCAACCACGGCGGTTCCTTCACCGT
GGATTCCGAACCGGGCAAAGGCGCCTGCTTCACCATTCTGCTGCCGCGCTGA

Upstream 100 bases:

>100_bases
CGCATGATATGTGTAATAACGGCTTTCATCTTCCTTTTTGGCACCTGTTACGCTAAAAAAAGAATATGAAGACGCAGTCA
ACCTGTGGAGACCCGAACCG

Downstream 100 bases:

>100_bases
CGGCGTGCAGACAGCTTTCCGGCTCAGCGCACAAAAAACGCGCCCCGTCGCATGACGGGGCGCGTCGTTTTGTCATTGTC
AGACCTGCTGCACCGGCTTA

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 763; Mature: 762

Protein sequence:

>763_residues
MPPRITLAPTPKQFVGRSISRDLTISLLVMLMVVVGGMASIQYISHSRTSLEELDNKADEYITRLADILSVPIWNFDTRT
IEQIGSVFTQYDLVNEVVIKDPAGHTLFSVTKAPDPDATLIRQRDIFYDGEIIGNVRVVLTLREYKRSLRRMLSTTALTI
GGVALVIVLATGVLLRIYLRRPLDVLLSSIDKVSKGDFRHDFSTIQQAELAAIARSFASMSAKVEAREKALQRMNSQLQE
EVAERERAEQALRNSEERYSLAVGGTNDGIWDWDLISNKVYFSPRWKEIIGFQDHEIPNEIPEWTSRVHPDDLAKILKAH
EMYLSRELPAFEVEYRLRHKDGSYRWILGRGLALWSDADQPYRMAGAHTDITDRKESERELLATKNRLDNILNSMPSLIV
GVSDNGIILQWNRTAEEETSVSARDAIGTPFENTLPEFSFLMGKVLQSLNSGETISLERKAITYSDRVRTFDIIIYPVTE
RGEHSAVIRIDDVTDRIRIEEMMVQTEKMMSVGGLAAGMAHEINNPLGGILQGAQNIVRRISTEIKANHAAADEVGCDLT
AIRAYMEKRGITRFLDGIQESGNRAAKIVSNMLEFSRRSESRRQLADMHALMDKTVELAANDYDLKKKYDFRHIELVRDY
APDLPGIHCTPTEIEQVLLNLLKNSAQAMAGRPKDSTEPPRITLRTRLQHDKVCIQVLDNGPGMDEETRKRVFEPFFTTK
SVGEGTGLGLSVSYFIITTNHGGSFTVDSEPGKGACFTILLPR

Sequences:

>Translated_763_residues
MPPRITLAPTPKQFVGRSISRDLTISLLVMLMVVVGGMASIQYISHSRTSLEELDNKADEYITRLADILSVPIWNFDTRT
IEQIGSVFTQYDLVNEVVIKDPAGHTLFSVTKAPDPDATLIRQRDIFYDGEIIGNVRVVLTLREYKRSLRRMLSTTALTI
GGVALVIVLATGVLLRIYLRRPLDVLLSSIDKVSKGDFRHDFSTIQQAELAAIARSFASMSAKVEAREKALQRMNSQLQE
EVAERERAEQALRNSEERYSLAVGGTNDGIWDWDLISNKVYFSPRWKEIIGFQDHEIPNEIPEWTSRVHPDDLAKILKAH
EMYLSRELPAFEVEYRLRHKDGSYRWILGRGLALWSDADQPYRMAGAHTDITDRKESERELLATKNRLDNILNSMPSLIV
GVSDNGIILQWNRTAEEETSVSARDAIGTPFENTLPEFSFLMGKVLQSLNSGETISLERKAITYSDRVRTFDIIIYPVTE
RGEHSAVIRIDDVTDRIRIEEMMVQTEKMMSVGGLAAGMAHEINNPLGGILQGAQNIVRRISTEIKANHAAADEVGCDLT
AIRAYMEKRGITRFLDGIQESGNRAAKIVSNMLEFSRRSESRRQLADMHALMDKTVELAANDYDLKKKYDFRHIELVRDY
APDLPGIHCTPTEIEQVLLNLLKNSAQAMAGRPKDSTEPPRITLRTRLQHDKVCIQVLDNGPGMDEETRKRVFEPFFTTK
SVGEGTGLGLSVSYFIITTNHGGSFTVDSEPGKGACFTILLPR
>Mature_762_residues
PPRITLAPTPKQFVGRSISRDLTISLLVMLMVVVGGMASIQYISHSRTSLEELDNKADEYITRLADILSVPIWNFDTRTI
EQIGSVFTQYDLVNEVVIKDPAGHTLFSVTKAPDPDATLIRQRDIFYDGEIIGNVRVVLTLREYKRSLRRMLSTTALTIG
GVALVIVLATGVLLRIYLRRPLDVLLSSIDKVSKGDFRHDFSTIQQAELAAIARSFASMSAKVEAREKALQRMNSQLQEE
VAERERAEQALRNSEERYSLAVGGTNDGIWDWDLISNKVYFSPRWKEIIGFQDHEIPNEIPEWTSRVHPDDLAKILKAHE
MYLSRELPAFEVEYRLRHKDGSYRWILGRGLALWSDADQPYRMAGAHTDITDRKESERELLATKNRLDNILNSMPSLIVG
VSDNGIILQWNRTAEEETSVSARDAIGTPFENTLPEFSFLMGKVLQSLNSGETISLERKAITYSDRVRTFDIIIYPVTER
GEHSAVIRIDDVTDRIRIEEMMVQTEKMMSVGGLAAGMAHEINNPLGGILQGAQNIVRRISTEIKANHAAADEVGCDLTA
IRAYMEKRGITRFLDGIQESGNRAAKIVSNMLEFSRRSESRRQLADMHALMDKTVELAANDYDLKKKYDFRHIELVRDYA
PDLPGIHCTPTEIEQVLLNLLKNSAQAMAGRPKDSTEPPRITLRTRLQHDKVCIQVLDNGPGMDEETRKRVFEPFFTTKS
VGEGTGLGLSVSYFIITTNHGGSFTVDSEPGKGACFTILLPR

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=408, Percent_Identity=28.4313725490196, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1790436, Length=267, Percent_Identity=30.3370786516854, Blast_Score=110, Evalue=4e-25,
Organism=Escherichia coli, GI1790300, Length=393, Percent_Identity=25.9541984732824, Blast_Score=103, Evalue=6e-23,
Organism=Escherichia coli, GI145693157, Length=293, Percent_Identity=25.5972696245734, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI87081816, Length=253, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082128, Length=251, Percent_Identity=26.6932270916335, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI48994928, Length=409, Percent_Identity=22.9828850855746, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788381, Length=262, Percent_Identity=25.5725190839695, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 85884; Mature: 85753

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPRITLAPTPKQFVGRSISRDLTISLLVMLMVVVGGMASIQYISHSRTSLEELDNKADE
CCCCCCCCCCCHHHHCCHHCCHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHH
YITRLADILSVPIWNFDTRTIEQIGSVFTQYDLVNEVVIKDPAGHTLFSVTKAPDPDATL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCCCCCHHH
IRQRDIFYDGEIIGNVRVVLTLREYKRSLRRMLSTTALTIGGVALVIVLATGVLLRIYLR
HHHCCCEECCEEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RPLDVLLSSIDKVSKGDFRHDFSTIQQAELAAIARSFASMSAKVEAREKALQRMNSQLQE
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVAERERAEQALRNSEERYSLAVGGTNDGIWDWDLISNKVYFSPRWKEIIGFQDHEIPNE
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEHHHHCCEEEECCCHHHHCCCCCCCCCHH
IPEWTSRVHPDDLAKILKAHEMYLSRELPAFEVEYRLRHKDGSYRWILGRGLALWSDADQ
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEECCEEEECCCCC
PYRMAGAHTDITDRKESERELLATKNRLDNILNSMPSLIVGVSDNGIILQWNRTAEEETS
CHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCHHHC
VSARDAIGTPFENTLPEFSFLMGKVLQSLNSGETISLERKAITYSDRVRTFDIIIYPVTE
CCHHHCCCCCHHHCCHHHHHHHHHHHHHCCCCCEEEEEHHEEEHHCCCEEEEEEEEECCC
RGEHSAVIRIDDVTDRIRIEEMMVQTEKMMSVGGLAAGMAHEINNPLGGILQGAQNIVRR
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ISTEIKANHAAADEVGCDLTAIRAYMEKRGITRFLDGIQESGNRAAKIVSNMLEFSRRSE
HHHHHHHCCCCHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SRRQLADMHALMDKTVELAANDYDLKKKYDFRHIELVRDYAPDLPGIHCTPTEIEQVLLN
HHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
LLKNSAQAMAGRPKDSTEPPRITLRTRLQHDKVCIQVLDNGPGMDEETRKRVFEPFFTTK
HHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCC
SVGEGTGLGLSVSYFIITTNHGGSFTVDSEPGKGACFTILLPR
CCCCCCCCCEEEEEEEEEECCCCEEEECCCCCCCCEEEEEECC
>Mature Secondary Structure 
PPRITLAPTPKQFVGRSISRDLTISLLVMLMVVVGGMASIQYISHSRTSLEELDNKADE
CCCCCCCCCCHHHHCCHHCCHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHH
YITRLADILSVPIWNFDTRTIEQIGSVFTQYDLVNEVVIKDPAGHTLFSVTKAPDPDATL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCCCCCHHH
IRQRDIFYDGEIIGNVRVVLTLREYKRSLRRMLSTTALTIGGVALVIVLATGVLLRIYLR
HHHCCCEECCEEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RPLDVLLSSIDKVSKGDFRHDFSTIQQAELAAIARSFASMSAKVEAREKALQRMNSQLQE
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVAERERAEQALRNSEERYSLAVGGTNDGIWDWDLISNKVYFSPRWKEIIGFQDHEIPNE
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEHHHHCCEEEECCCHHHHCCCCCCCCCHH
IPEWTSRVHPDDLAKILKAHEMYLSRELPAFEVEYRLRHKDGSYRWILGRGLALWSDADQ
HHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEECCEEEECCCCC
PYRMAGAHTDITDRKESERELLATKNRLDNILNSMPSLIVGVSDNGIILQWNRTAEEETS
CHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCHHHC
VSARDAIGTPFENTLPEFSFLMGKVLQSLNSGETISLERKAITYSDRVRTFDIIIYPVTE
CCHHHCCCCCHHHCCHHHHHHHHHHHHHCCCCCEEEEEHHEEEHHCCCEEEEEEEEECCC
RGEHSAVIRIDDVTDRIRIEEMMVQTEKMMSVGGLAAGMAHEINNPLGGILQGAQNIVRR
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ISTEIKANHAAADEVGCDLTAIRAYMEKRGITRFLDGIQESGNRAAKIVSNMLEFSRRSE
HHHHHHHCCCCHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SRRQLADMHALMDKTVELAANDYDLKKKYDFRHIELVRDYAPDLPGIHCTPTEIEQVLLN
HHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
LLKNSAQAMAGRPKDSTEPPRITLRTRLQHDKVCIQVLDNGPGMDEETRKRVFEPFFTTK
HHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCC
SVGEGTGLGLSVSYFIITTNHGGSFTVDSEPGKGACFTILLPR
CCCCCCCCCEEEEEEEEEECCCCEEEECCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]