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The map label for this gene is 78355470

Identifier: 78355470

GI number: 78355470

Start: 422088

End: 422954

Strand: Reverse

Name: 78355470

Synonym: Dde_0423

Alternate gene names: NA

Gene position: 422954-422088 (Counterclockwise)

Preceding gene: 78355479

Following gene: 78355469

Centisome position: 11.34

GC content: 62.28

Gene sequence:

>867_bases
ATGCAGCCGTATTTCATTGCAGAAGTTTCCAGTAACCACAACCGCGATCTGGACCGTTGTCTGGCATTTATCGAAACAGC
CGCAGGCTGCGGATGTGATGCGGTCAAATTCCAGCTCTTCCGGCTGGACGAGCTGTTTGCGCCGGAAGTCTTTGCCGCCA
TGCCGCAGGTAACCGGACGCAGAGCATGGGAACTGCCTGAAGACTACCTGCCCGTGCTGGCGCAGTCCTGCCGCAGACAC
GGTGTGGCATTCAGCGCCACCCCTTTTTCGCTTCAGGCGGTACATGCACTGCAACCTCATGTCGATTTTTATAAAATTGC
ATCCTACGAACTGCTCTGGGATGCCCTGCTGCACGCCTGTGCCGGCACGGGCAAGCCCGTTGTGCTTTCCACCGGCATGG
CAGCTCTGCAGGAAGTGGCCCATGCCGCGGACGTGCTGCGCACCGCCGGCTGCCGTGATATGACGCTGCTGCACTGCACG
TCCGGCTATCCCGCCCCGCCGGAACAATGCAATCTTGCGGCGGTGGAGACCCTGCGCAGGCAGTTCGGCTGCGCCGCAGG
CTGGTCCGACCATACCGTGCATGCCGGTGTCATTCACCGCGCCGTACACCGCTGGGGTGCTCAGGTTGTGGAATTTCATC
TTGATCTTGACGGCGACGGTGCGGAATACGCCAGCGGCCACTGCTGGCTGCCCCATCAGATAGCACCGGTCATCAGCCAG
ATACGGCAGGCTTTCAGCGCCGACGGCAACGGTGTGAAAGAGCCTGCGCCATGCGAGGAGCAGGAGCGCAACTGGCGCGC
CGACCCGCAGGACGGTCTGCGTCCGCTGCGCGCAGTGCGCGCCGGTCTGGAGGCGGAACATGCATGA

Upstream 100 bases:

>100_bases
GCGCACGGCGCGCCGCCGCACCGCACCGGCGTGCACAAACACACGCCCCCGTCAGCACGGTGACGGTATGGCGCAACAGC
CGCAAAGCCGGAGATACCAC

Downstream 100 bases:

>100_bases
CAGCCCGTTTGCCGTCCGTCTGCTGGCGGACGAGCCGGCCTTCGGCCCTCTGGCCCTGCAATGGATTTATGAACAATGGG
GGGCCGCCCCCGGTGTGACG

Product: N-acetylneuraminate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MQPYFIAEVSSNHNRDLDRCLAFIETAAGCGCDAVKFQLFRLDELFAPEVFAAMPQVTGRRAWELPEDYLPVLAQSCRRH
GVAFSATPFSLQAVHALQPHVDFYKIASYELLWDALLHACAGTGKPVVLSTGMAALQEVAHAADVLRTAGCRDMTLLHCT
SGYPAPPEQCNLAAVETLRRQFGCAAGWSDHTVHAGVIHRAVHRWGAQVVEFHLDLDGDGAEYASGHCWLPHQIAPVISQ
IRQAFSADGNGVKEPAPCEEQERNWRADPQDGLRPLRAVRAGLEAEHA

Sequences:

>Translated_288_residues
MQPYFIAEVSSNHNRDLDRCLAFIETAAGCGCDAVKFQLFRLDELFAPEVFAAMPQVTGRRAWELPEDYLPVLAQSCRRH
GVAFSATPFSLQAVHALQPHVDFYKIASYELLWDALLHACAGTGKPVVLSTGMAALQEVAHAADVLRTAGCRDMTLLHCT
SGYPAPPEQCNLAAVETLRRQFGCAAGWSDHTVHAGVIHRAVHRWGAQVVEFHLDLDGDGAEYASGHCWLPHQIAPVISQ
IRQAFSADGNGVKEPAPCEEQERNWRADPQDGLRPLRAVRAGLEAEHA
>Mature_288_residues
MQPYFIAEVSSNHNRDLDRCLAFIETAAGCGCDAVKFQLFRLDELFAPEVFAAMPQVTGRRAWELPEDYLPVLAQSCRRH
GVAFSATPFSLQAVHALQPHVDFYKIASYELLWDALLHACAGTGKPVVLSTGMAALQEVAHAADVLRTAGCRDMTLLHCT
SGYPAPPEQCNLAAVETLRRQFGCAAGWSDHTVHAGVIHRAVHRWGAQVVEFHLDLDGDGAEYASGHCWLPHQIAPVISQ
IRQAFSADGNGVKEPAPCEEQERNWRADPQDGLRPLRAVRAGLEAEHA

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=271, Percent_Identity=27.3062730627306, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21357081, Length=255, Percent_Identity=30.9803921568627, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 31569; Mature: 31569

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPYFIAEVSSNHNRDLDRCLAFIETAAGCGCDAVKFQLFRLDELFAPEVFAAMPQVTGR
CCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCC
RAWELPEDYLPVLAQSCRRHGVAFSATPFSLQAVHALQPHVDFYKIASYELLWDALLHAC
CCCCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AGTGKPVVLSTGMAALQEVAHAADVLRTAGCRDMTLLHCTSGYPAPPEQCNLAAVETLRR
CCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHCCHHHHHHHHH
QFGCAAGWSDHTVHAGVIHRAVHRWGAQVVEFHLDLDGDGAEYASGHCWLPHQIAPVISQ
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
IRQAFSADGNGVKEPAPCEEQERNWRADPQDGLRPLRAVRAGLEAEHA
HHHHHCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQPYFIAEVSSNHNRDLDRCLAFIETAAGCGCDAVKFQLFRLDELFAPEVFAAMPQVTGR
CCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCC
RAWELPEDYLPVLAQSCRRHGVAFSATPFSLQAVHALQPHVDFYKIASYELLWDALLHAC
CCCCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AGTGKPVVLSTGMAALQEVAHAADVLRTAGCRDMTLLHCTSGYPAPPEQCNLAAVETLRR
CCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHCCHHHHHHHHH
QFGCAAGWSDHTVHAGVIHRAVHRWGAQVVEFHLDLDGDGAEYASGHCWLPHQIAPVISQ
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
IRQAFSADGNGVKEPAPCEEQERNWRADPQDGLRPLRAVRAGLEAEHA
HHHHHCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]