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The map label for this gene is cobB [H]

Identifier: 78355390

GI number: 78355390

Start: 333017

End: 334537

Strand: Reverse

Name: cobB [H]

Synonym: Dde_0343

Alternate gene names: 78355390

Gene position: 334537-333017 (Counterclockwise)

Preceding gene: 78355391

Following gene: 78355389

Centisome position: 8.97

GC content: 61.93

Gene sequence:

>1521_bases
ATGCATCCGCTCATCACCATTGCCGGAACCCACAGCGGGTGCGGCAAAACAACAGTCAGTCTGGCACTTATGGCTGCCTT
GCGCCGCGCCGGATTTGCCGTGCAGCCGTTCAAGGCAGGGCCGGACTTTATTGATACGGGGCACCACGGCACCGTAACCG
GACGGCAGGGCCAGAATATTGACGGCTGGATAATGGGCCGTCAGGCGTGCTGTGAACTGGTATCACGCGCCATGAGCAAT
CCCGCGGGGCATCCTGCGGACATCGGTGTCATTGAAGGCGTTATGGGCCTTTTTGACGGCGCGTCCGGCTCGTGCGACAG
CGGCTCCACCGCGCAACTGGCCTCATGGCTGCAAGCCCCCGTGGTGCTTGTTGCGGATGCACGCTCCATGGCCCGTTCCG
CCGCGGCGCTGGTGTCCGGTTATGTCCGGTTTGACCCGCATCTGCCGTTTGCAGGCGTTATCTTCAACAGGGTGGGCAGC
AGCAACCACCGCAGTCTCATTGCCGAAGCCATGCGCACGGCATGTCCGGACATCCCCGTGCTGGGCTTTCTGCCACGCGA
TGAATCGCTGGAAATACCGGCCCGCCATCTGGGACTGAACACCGCGGCGGAATCTCCGCTGACAGCCGGAGTGCAGGACA
GGCTTGCCCGCTGGTTCACGGCCGGAGCCAGTCTGAACAGCATTCTGACAGCAGCGCGTCGGGCAGCAGCGTCTCAGGCA
GCAACGCGTCAGACCGCAGAATGTCAGGCAGCAGAACGTGCCGGACAATGTGTTACGCGGCAGTCCGGTTCAGCACCCGA
CGGCATTGTACAGTCCCGCAGCACTGCACAAACGCCTGTCCGCATCGGCGTTTCAGCCGATGAAGCATTCTGCTTTGTCT
ATGCTGAAAACCTGCGGTTGCTCCAATCAGCCGGAGCCGAACTGGTCTTTTTTTCACCGCTGCATGATGCGCACCTGCCT
GCCGGCCTGCATGGGGTGTATCTGACTGGAGGCTATCCGGAACTTCACGCGGACAGACTGTATGAAAACACCCTGATGCG
TACCGCTGTATATGATTTTTCTCTCGCCGGAGGCATAGTGTATGCCGAGTGCGGCGGCTTCATGTATCTGATGCAGCAGC
TGTACGACCAGCAGGGAGCATCGTGGCCCATGTGCGGCTGCCTGCCTTTTTCATGCGCCATGGGCACACGCTTCAGGGCG
CTGGGCTACCGGCAGGTACGCACCACTGCGGATTCGCCTCTCGGCGCGGCAGGCACAGTCCTGCGCGGGCACGAATTTCA
TTACTCGCACCTGTGCGCGCCGCCCGCCGGAGACGATACAATGAATATTACCAACATCTATGACGCCACAGACCGCAACG
GCACGCCCCTGAACAGCGGTACCGGCGACGCCCCCGCAGCGGCAGGCCACCTGCAGCGCAACACACTGGGGTCTTACGTG
CACCTGCACTTTGCATCCTGCCCCGACGCGGCCCGCGCTTTTGTCGGCGCATGCCGCCGTTCATCCGTAACCACGCCCTG
A

Upstream 100 bases:

>100_bases
ACGGCGGAGCACCGGAACTGGAAGCAACCGCACGCACGGAAGACGCGGCAATCATCCGCGACTTTTTTCTGCGTGACGAA
GCGGAGTAACGCACGGTTTC

Downstream 100 bases:

>100_bases
CAGCGCAACATCCGCAGTGCCGGAGGAAAATATATGGATACCCCCGTTCTTCAGCAATGCTTCGCACCTCAGGCCATCGA
GGCGCGCTCCTTTGCCATTA

Product: cobyrinate a,c-diamide synthase / hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MHPLITIAGTHSGCGKTTVSLALMAALRRAGFAVQPFKAGPDFIDTGHHGTVTGRQGQNIDGWIMGRQACCELVSRAMSN
PAGHPADIGVIEGVMGLFDGASGSCDSGSTAQLASWLQAPVVLVADARSMARSAAALVSGYVRFDPHLPFAGVIFNRVGS
SNHRSLIAEAMRTACPDIPVLGFLPRDESLEIPARHLGLNTAAESPLTAGVQDRLARWFTAGASLNSILTAARRAAASQA
ATRQTAECQAAERAGQCVTRQSGSAPDGIVQSRSTAQTPVRIGVSADEAFCFVYAENLRLLQSAGAELVFFSPLHDAHLP
AGLHGVYLTGGYPELHADRLYENTLMRTAVYDFSLAGGIVYAECGGFMYLMQQLYDQQGASWPMCGCLPFSCAMGTRFRA
LGYRQVRTTADSPLGAAGTVLRGHEFHYSHLCAPPAGDDTMNITNIYDATDRNGTPLNSGTGDAPAAAGHLQRNTLGSYV
HLHFASCPDAARAFVGACRRSSVTTP

Sequences:

>Translated_506_residues
MHPLITIAGTHSGCGKTTVSLALMAALRRAGFAVQPFKAGPDFIDTGHHGTVTGRQGQNIDGWIMGRQACCELVSRAMSN
PAGHPADIGVIEGVMGLFDGASGSCDSGSTAQLASWLQAPVVLVADARSMARSAAALVSGYVRFDPHLPFAGVIFNRVGS
SNHRSLIAEAMRTACPDIPVLGFLPRDESLEIPARHLGLNTAAESPLTAGVQDRLARWFTAGASLNSILTAARRAAASQA
ATRQTAECQAAERAGQCVTRQSGSAPDGIVQSRSTAQTPVRIGVSADEAFCFVYAENLRLLQSAGAELVFFSPLHDAHLP
AGLHGVYLTGGYPELHADRLYENTLMRTAVYDFSLAGGIVYAECGGFMYLMQQLYDQQGASWPMCGCLPFSCAMGTRFRA
LGYRQVRTTADSPLGAAGTVLRGHEFHYSHLCAPPAGDDTMNITNIYDATDRNGTPLNSGTGDAPAAAGHLQRNTLGSYV
HLHFASCPDAARAFVGACRRSSVTTP
>Mature_506_residues
MHPLITIAGTHSGCGKTTVSLALMAALRRAGFAVQPFKAGPDFIDTGHHGTVTGRQGQNIDGWIMGRQACCELVSRAMSN
PAGHPADIGVIEGVMGLFDGASGSCDSGSTAQLASWLQAPVVLVADARSMARSAAALVSGYVRFDPHLPFAGVIFNRVGS
SNHRSLIAEAMRTACPDIPVLGFLPRDESLEIPARHLGLNTAAESPLTAGVQDRLARWFTAGASLNSILTAARRAAASQA
ATRQTAECQAAERAGQCVTRQSGSAPDGIVQSRSTAQTPVRIGVSADEAFCFVYAENLRLLQSAGAELVFFSPLHDAHLP
AGLHGVYLTGGYPELHADRLYENTLMRTAVYDFSLAGGIVYAECGGFMYLMQQLYDQQGASWPMCGCLPFSCAMGTRFRA
LGYRQVRTTADSPLGAAGTVLRGHEFHYSHLCAPPAGDDTMNITNIYDATDRNGTPLNSGTGDAPAAAGHLQRNTLGSYV
HLHFASCPDAARAFVGACRRSSVTTP

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 53330; Mature: 53330

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPLITIAGTHSGCGKTTVSLALMAALRRAGFAVQPFKAGPDFIDTGHHGTVTGRQGQNI
CCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCEEECCCCCCC
DGWIMGRQACCELVSRAMSNPAGHPADIGVIEGVMGLFDGASGSCDSGSTAQLASWLQAP
CCEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCC
VVLVADARSMARSAAALVSGYVRFDPHLPFAGVIFNRVGSSNHRSLIAEAMRTACPDIPV
EEEEECHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCE
LGFLPRDESLEIPARHLGLNTAAESPLTAGVQDRLARWFTAGASLNSILTAARRAAASQA
EEECCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ATRQTAECQAAERAGQCVTRQSGSAPDGIVQSRSTAQTPVRIGVSADEAFCFVYAENLRL
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCEEEECCCCCEEEEEEHHHHHH
LQSAGAELVFFSPLHDAHLPAGLHGVYLTGGYPELHADRLYENTLMRTAVYDFSLAGGIV
HHHCCCCEEEECCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
YAECGGFMYLMQQLYDQQGASWPMCGCLPFSCAMGTRFRALGYRQVRTTADSPLGAAGTV
EECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHCHHHHHHCCCCCCCCCCCE
LRGHEFHYSHLCAPPAGDDTMNITNIYDATDRNGTPLNSGTGDAPAAAGHLQRNTLGSYV
ECCCCCCHHEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEE
HLHFASCPDAARAFVGACRRSSVTTP
EEEECCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHPLITIAGTHSGCGKTTVSLALMAALRRAGFAVQPFKAGPDFIDTGHHGTVTGRQGQNI
CCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCEEECCCCCCC
DGWIMGRQACCELVSRAMSNPAGHPADIGVIEGVMGLFDGASGSCDSGSTAQLASWLQAP
CCEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCC
VVLVADARSMARSAAALVSGYVRFDPHLPFAGVIFNRVGSSNHRSLIAEAMRTACPDIPV
EEEEECHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCE
LGFLPRDESLEIPARHLGLNTAAESPLTAGVQDRLARWFTAGASLNSILTAARRAAASQA
EEECCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ATRQTAECQAAERAGQCVTRQSGSAPDGIVQSRSTAQTPVRIGVSADEAFCFVYAENLRL
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCEEEECCCCCEEEEEEHHHHHH
LQSAGAELVFFSPLHDAHLPAGLHGVYLTGGYPELHADRLYENTLMRTAVYDFSLAGGIV
HHHCCCCEEEECCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
YAECGGFMYLMQQLYDQQGASWPMCGCLPFSCAMGTRFRALGYRQVRTTADSPLGAAGTV
EECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHCHHHHHHCCCCCCCCCCCE
LRGHEFHYSHLCAPPAGDDTMNITNIYDATDRNGTPLNSGTGDAPAAAGHLQRNTLGSYV
ECCCCCCHHEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEE
HLHFASCPDAARAFVGACRRSSVTTP
EEEECCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA