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The map label for this gene is cysW [H]

Identifier: 78355280

GI number: 78355280

Start: 218062

End: 218760

Strand: Reverse

Name: cysW [H]

Synonym: Dde_0233

Alternate gene names: 78355280

Gene position: 218760-218062 (Counterclockwise)

Preceding gene: 78355281

Following gene: 78355279

Centisome position: 5.86

GC content: 60.8

Gene sequence:

>699_bases
ATGAGCTTTATTCTGGACGGAATGACACAGGCATTCGGCCTGCTGATGGACGGCAATCCCGAAACATGGTCAGCCGTCTA
CGCCACAGTGGCGGTAACCACCATGTCTGTGGCGGCCAGCGTTATTCTGGGCGCGCCGCTGGGTTTTCTGCTGGGATACT
GTTCATTCCCGGGCAAGCGGGCGCTGCGCATGCTTGCGGACACGCTGCTTTCTTTTCCCACCGTGGTCATAGGGCTTATC
GTCTATGCCCTGCTGTCCAGCAGAGGACCGCTGGGCGGGGCGGGGCTGCTGTTCACCCTGCCGGGGGTGGCCATAGGTCA
GACCCTGCTGGGACTGCCCATGGTCATAGCGCTGACCGCCAATGCCGTGGAATACGCCGACACCCGCCTGCGTGACACGC
TGCTCACGCTCGGGGCTTCGGGCGGACAGGTGCTGCGGGCCATGCTGTGGGAAGTGCGTTATCATCTGCTGCTTGCCGCT
GTGGCCGCTTACGGACGCATTGTGTCCGAGGTGGGCATATCCATGATGGTGGGCGGCAACATAAAGTGGCACACCCGCAC
CATAACCACGGCCATTGCGCTGGAAACAGGCAAAGGCGAGTTCGCCATGGGCATTGCACTGGGCGTGGTGCTGATGGTCA
TAGCCTTTCTGGTCAACCTTTCTCTTTCCGGTCTTAAACGCAGGGCGGTGATACGATGA

Upstream 100 bases:

>100_bases
ACCCGTTCGCCCCTCTGTCATTACAGGTCAGTATACGTCAGTACAGGCCGCCGGCAGCGTATTTTCTCCGGCTGGCACCC
AAATACTACGGAAGCCACGC

Downstream 100 bases:

>100_bases
ACCCGGCTGACCATGACACGGCGCCGCTGTACAGTCTGCGCAACGTGACCCAGCAGTACACGGGCAACGACGGCGCGCGG
CATACGGCGCTGGATATTGC

Product: ABC transporter permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSFILDGMTQAFGLLMDGNPETWSAVYATVAVTTMSVAASVILGAPLGFLLGYCSFPGKRALRMLADTLLSFPTVVIGLI
VYALLSSRGPLGGAGLLFTLPGVAIGQTLLGLPMVIALTANAVEYADTRLRDTLLTLGASGGQVLRAMLWEVRYHLLLAA
VAAYGRIVSEVGISMMVGGNIKWHTRTITTAIALETGKGEFAMGIALGVVLMVIAFLVNLSLSGLKRRAVIR

Sequences:

>Translated_232_residues
MSFILDGMTQAFGLLMDGNPETWSAVYATVAVTTMSVAASVILGAPLGFLLGYCSFPGKRALRMLADTLLSFPTVVIGLI
VYALLSSRGPLGGAGLLFTLPGVAIGQTLLGLPMVIALTANAVEYADTRLRDTLLTLGASGGQVLRAMLWEVRYHLLLAA
VAAYGRIVSEVGISMMVGGNIKWHTRTITTAIALETGKGEFAMGIALGVVLMVIAFLVNLSLSGLKRRAVIR
>Mature_231_residues
SFILDGMTQAFGLLMDGNPETWSAVYATVAVTTMSVAASVILGAPLGFLLGYCSFPGKRALRMLADTLLSFPTVVIGLIV
YALLSSRGPLGGAGLLFTLPGVAIGQTLLGLPMVIALTANAVEYADTRLRDTLLTLGASGGQVLRAMLWEVRYHLLLAAV
AAYGRIVSEVGISMMVGGNIKWHTRTITTAIALETGKGEFAMGIALGVVLMVIAFLVNLSLSGLKRRAVIR

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4662

COG function: function code H; ABC-type tungstate transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=184, Percent_Identity=27.1739130434783, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24360; Mature: 24228

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFILDGMTQAFGLLMDGNPETWSAVYATVAVTTMSVAASVILGAPLGFLLGYCSFPGKR
CCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHH
ALRMLADTLLSFPTVVIGLIVYALLSSRGPLGGAGLLFTLPGVAIGQTLLGLPMVIALTA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHH
NAVEYADTRLRDTLLTLGASGGQVLRAMLWEVRYHLLLAAVAAYGRIVSEVGISMMVGGN
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
IKWHTRTITTAIALETGKGEFAMGIALGVVLMVIAFLVNLSLSGLKRRAVIR
EEEEHHEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
>Mature Secondary Structure 
SFILDGMTQAFGLLMDGNPETWSAVYATVAVTTMSVAASVILGAPLGFLLGYCSFPGKR
CHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHH
ALRMLADTLLSFPTVVIGLIVYALLSSRGPLGGAGLLFTLPGVAIGQTLLGLPMVIALTA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHH
NAVEYADTRLRDTLLTLGASGGQVLRAMLWEVRYHLLLAAVAAYGRIVSEVGISMMVGGN
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
IKWHTRTITTAIALETGKGEFAMGIALGVVLMVIAFLVNLSLSGLKRRAVIR
EEEEHHEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]