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The map label for this gene is rnr [C]

Identifier: 78355220

GI number: 78355220

Start: 156038

End: 158134

Strand: Reverse

Name: rnr [C]

Synonym: Dde_0173

Alternate gene names: 78355220

Gene position: 158134-156038 (Counterclockwise)

Preceding gene: 78355221

Following gene: 78355219

Centisome position: 4.24

GC content: 61.18

Gene sequence:

>2097_bases
ATGAGCGCTACCTCCCCTCTGGTCCAATACCCCGGCCCGGGCTGCATCGTCGAATTCATGCAGGGCAACAAGCCCCAGAT
AGCATGGGTTCAGGAAGAACAGTCCGGCAAACTGCGCCTTCTCACCCAGAGCAAGCGGGAGACAAAGCTCGCAGCGGCAC
GCGTCATGCCATGGGCCGGTCCGCAGTACGGTGCCGACAAATCACGTCAGGAAGCACTGGAACTGCTGAACCAGCACGAA
GAACGCCGCAACACCAGAGCGGCCGCGCTTGACCCGCTGGAACTGTGGGAACTGGCGCAGGGCGAAGTACAGGCTGCCAC
GGCGCAGTGGTTTGCCGAACTGCTGCACGAATCGCCCGACGCAGACGACATAGCCGCCATGGGCCGCGTGCTGCTGGAAT
GCAAGACACATTTCAAGTTTCAGTCGCCGGAGTTTGAAATATACGACGCAGAAAAAGTGCACGCCCGCATGACCGAACAG
GAAGCCCGCCGGAAACGCGAACAGCTCGCATCCGAAGGTCATGATTTTCTGCGCGCTCTGTGGGAAACCCATCAGAAAAG
ACGCACCCCGCCCTGTACGCCTGAAGACGCCGGACTGGCCGCCGAAATTGAAGCCCTGCTGCGCAAACGCATCGCAGAAC
CGGACGATCACGACTCAGAACAGTTGTGGAAACAGATATCCAAAGGGCTGCCGGACGTGCCGCACCTGCCTCTGCTGCTG
GCACAGGCATGGGGTATTGTGCCCGCCCACCATAATTTTCATCTGGACAGGGCCGATTATGACAGATCGCCCGACTGGCA
CGCTCCCCATGCACAGGCACTCGCAGACCTGCGCCGGCGTGTGCTTGCCGCACGCACCGAACCCTGCGGTATTCCGTTCA
TCAGCATCGATTCCTCCTCCACGCGTGACATTGACGATGCCTTCCATATCGAACCGCGCGCCGACGGCGGCCACCGCCTG
CGGCTGGCCATTGCCTGCCCCGCTCTGGGATGGGAATTCGGCAGCGAACTGGACAAAGCCGTCATGCGCCGCGCCACCAG
CATATATCTTCCCGAAGGCAATCTGCACATGCTGCCGGAAGAGCTGGGCACGGACTTTTTCAGTCTCATAGGACAGCAGG
AGCGGCCGGCTCTGGTCATGGAATTTGACATTGCTCCCGCCGGACAACTGGAAGCCACAACCCTGAAGGCGTGCTGGGTA
CAGCTGGCCGCCAACCTGAGTTATGCCGACTGCGAAGCCGTGCTGAACGGCGATCCGGGCTGGGACGCCCCCGACAACCC
CGCCGCCGCCTTTGCTGACCAGCTGAAGGCCGGAGCCGCGCTTTCGCGCATCTTGCTGGAACAACGGGTGTCCTGCGGGG
CCGTGGTCATCGAACGCCCGGACCCCAAAACCACTCTTACCGGCACCGGAGCCGACACACAGGTGGAAATTGAGCACGAC
AGCCCCACTCCGGCATCGTGCCTGCTGGTCAGCGAAATGATGATACTGGCCAACAGCGGTATTGCCCTGTGGGCAAAAGA
CCGTGACATAGCCCTGCTGCACCGCACGCAGGACGTGGGCGTGCCCAAGGAATACGCCGGAGTATGGGACCAGCCCCATG
ACATCGCCCGCGTGGTCAAGGCGCTGTCGTCCGCCGTGCTGGAAACGGCCCCGCGCAGGCATTCAGGCATAGGCGTACCC
GCCTACAGCCCTGTCACATCGCCACTGCGGCGCTATCCCGACCTTGTCAACGTTGCGCAACTCATACATTATCTCGGCAC
CGGCACTCCCCGCTGGTCGCGCGACGAGCTTGATGCCATGCTGCCGCTGCTCACCGCACGGCTGGATGCCGCAGGGCAGG
TACAACGTTTCCGCCCAAGATACTGGAAACTGCTGTACTTCAAGCAGAAAGGCGATAAAACGTGGTGGGACGCAGTGGTG
ACGGACGAAAACGATGCCTTTGTCACCGTGTCGCTGCCCGATCAGCAGATTTTTGTGCGCGGACGCAGGTCCTCTTTCGG
CGAAAGGGCGCACCCCGGTACCAGACTTATGGTGCGCATCGGCAAAGTGCATCCGCTTAACAACGAGATCCAGATACTGG
ACGTCATGGAACAATAG

Upstream 100 bases:

>100_bases
GGCCAGCGGTCTTTCAAGCATTAACCGGCAGCGGAGGGCGGCATGCCGCCCTCCGCATACCGCTGAAACAAGCAACCACG
CGCAAACACAAGCAGGAATC

Downstream 100 bases:

>100_bases
TCCCGCGCAACGCGCATTACGCAAGGAGAACTCCCCTATGGGCTACCTGCTCTGGCTCGTCACCGCCTATGTCATCGGCT
CTGTCCCCTTCGGTCTGGTC

Product: RNB-like family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 698; Mature: 697

Protein sequence:

>698_residues
MSATSPLVQYPGPGCIVEFMQGNKPQIAWVQEEQSGKLRLLTQSKRETKLAAARVMPWAGPQYGADKSRQEALELLNQHE
ERRNTRAAALDPLELWELAQGEVQAATAQWFAELLHESPDADDIAAMGRVLLECKTHFKFQSPEFEIYDAEKVHARMTEQ
EARRKREQLASEGHDFLRALWETHQKRRTPPCTPEDAGLAAEIEALLRKRIAEPDDHDSEQLWKQISKGLPDVPHLPLLL
AQAWGIVPAHHNFHLDRADYDRSPDWHAPHAQALADLRRRVLAARTEPCGIPFISIDSSSTRDIDDAFHIEPRADGGHRL
RLAIACPALGWEFGSELDKAVMRRATSIYLPEGNLHMLPEELGTDFFSLIGQQERPALVMEFDIAPAGQLEATTLKACWV
QLAANLSYADCEAVLNGDPGWDAPDNPAAAFADQLKAGAALSRILLEQRVSCGAVVIERPDPKTTLTGTGADTQVEIEHD
SPTPASCLLVSEMMILANSGIALWAKDRDIALLHRTQDVGVPKEYAGVWDQPHDIARVVKALSSAVLETAPRRHSGIGVP
AYSPVTSPLRRYPDLVNVAQLIHYLGTGTPRWSRDELDAMLPLLTARLDAAGQVQRFRPRYWKLLYFKQKGDKTWWDAVV
TDENDAFVTVSLPDQQIFVRGRRSSFGERAHPGTRLMVRIGKVHPLNNEIQILDVMEQ

Sequences:

>Translated_698_residues
MSATSPLVQYPGPGCIVEFMQGNKPQIAWVQEEQSGKLRLLTQSKRETKLAAARVMPWAGPQYGADKSRQEALELLNQHE
ERRNTRAAALDPLELWELAQGEVQAATAQWFAELLHESPDADDIAAMGRVLLECKTHFKFQSPEFEIYDAEKVHARMTEQ
EARRKREQLASEGHDFLRALWETHQKRRTPPCTPEDAGLAAEIEALLRKRIAEPDDHDSEQLWKQISKGLPDVPHLPLLL
AQAWGIVPAHHNFHLDRADYDRSPDWHAPHAQALADLRRRVLAARTEPCGIPFISIDSSSTRDIDDAFHIEPRADGGHRL
RLAIACPALGWEFGSELDKAVMRRATSIYLPEGNLHMLPEELGTDFFSLIGQQERPALVMEFDIAPAGQLEATTLKACWV
QLAANLSYADCEAVLNGDPGWDAPDNPAAAFADQLKAGAALSRILLEQRVSCGAVVIERPDPKTTLTGTGADTQVEIEHD
SPTPASCLLVSEMMILANSGIALWAKDRDIALLHRTQDVGVPKEYAGVWDQPHDIARVVKALSSAVLETAPRRHSGIGVP
AYSPVTSPLRRYPDLVNVAQLIHYLGTGTPRWSRDELDAMLPLLTARLDAAGQVQRFRPRYWKLLYFKQKGDKTWWDAVV
TDENDAFVTVSLPDQQIFVRGRRSSFGERAHPGTRLMVRIGKVHPLNNEIQILDVMEQ
>Mature_697_residues
SATSPLVQYPGPGCIVEFMQGNKPQIAWVQEEQSGKLRLLTQSKRETKLAAARVMPWAGPQYGADKSRQEALELLNQHEE
RRNTRAAALDPLELWELAQGEVQAATAQWFAELLHESPDADDIAAMGRVLLECKTHFKFQSPEFEIYDAEKVHARMTEQE
ARRKREQLASEGHDFLRALWETHQKRRTPPCTPEDAGLAAEIEALLRKRIAEPDDHDSEQLWKQISKGLPDVPHLPLLLA
QAWGIVPAHHNFHLDRADYDRSPDWHAPHAQALADLRRRVLAARTEPCGIPFISIDSSSTRDIDDAFHIEPRADGGHRLR
LAIACPALGWEFGSELDKAVMRRATSIYLPEGNLHMLPEELGTDFFSLIGQQERPALVMEFDIAPAGQLEATTLKACWVQ
LAANLSYADCEAVLNGDPGWDAPDNPAAAFADQLKAGAALSRILLEQRVSCGAVVIERPDPKTTLTGTGADTQVEIEHDS
PTPASCLLVSEMMILANSGIALWAKDRDIALLHRTQDVGVPKEYAGVWDQPHDIARVVKALSSAVLETAPRRHSGIGVPA
YSPVTSPLRRYPDLVNVAQLIHYLGTGTPRWSRDELDAMLPLLTARLDAAGQVQRFRPRYWKLLYFKQKGDKTWWDAVVT
DENDAFVTVSLPDQQIFVRGRRSSFGERAHPGTRLMVRIGKVHPLNNEIQILDVMEQ

Specific function: 3'-5'Exoribonuclease That Participates In An Essential Cell Function. Acts Nonspecifically On Poly(A), Poly(U) And Ribosomal RNAs. Required For The Expression Of VIrulence Genes In Enteroinvasive Strains Of E.Coli. [C]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonuclease II (RNB) family [H]

Homologues:

Organism=Homo sapiens, GI134288890, Length=352, Percent_Identity=23.2954545454545, Blast_Score=73, Evalue=9e-13,
Organism=Escherichia coli, GI87082383, Length=356, Percent_Identity=26.4044943820225, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1787542, Length=350, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6323943, Length=441, Percent_Identity=24.4897959183673, Blast_Score=116, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001900
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00773 RNB [H]

EC number: 3.1.13.1

Molecular weight: Translated: 77919; Mature: 77788

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATSPLVQYPGPGCIVEFMQGNKPQIAWVQEEQSGKLRLLTQSKRETKLAAARVMPWAG
CCCCCCCCCCCCCCHHHHHHCCCCCCEEEEEECCCCCEEEEECCHHHHHHHHHHCCCCCC
PQYGADKSRQEALELLNQHEERRNTRAAALDPLELWELAQGEVQAATAQWFAELLHESPD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
ADDIAAMGRVLLECKTHFKFQSPEFEIYDAEKVHARMTEQEARRKREQLASEGHDFLRAL
HHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WETHQKRRTPPCTPEDAGLAAEIEALLRKRIAEPDDHDSEQLWKQISKGLPDVPHLPLLL
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHH
AQAWGIVPAHHNFHLDRADYDRSPDWHAPHAQALADLRRRVLAARTEPCGIPFISIDSSS
HHHHCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCC
TRDIDDAFHIEPRADGGHRLRLAIACPALGWEFGSELDKAVMRRATSIYLPEGNLHMLPE
CCCCCCCEEECCCCCCCCEEEEEEECCHHCCHHHHHHHHHHHHHHHEEEECCCCCEECHH
ELGTDFFSLIGQQERPALVMEFDIAPAGQLEATTLKACWVQLAANLSYADCEAVLNGDPG
HHCCHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
WDAPDNPAAAFADQLKAGAALSRILLEQRVSCGAVVIERPDPKTTLTGTGADTQVEIEHD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEECCCCCCEEEEECC
SPTPASCLLVSEMMILANSGIALWAKDRDIALLHRTQDVGVPKEYAGVWDQPHDIARVVK
CCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCHHHHCCCCCCHHHHHHHH
ALSSAVLETAPRRHSGIGVPAYSPVTSPLRRYPDLVNVAQLIHYLGTGTPRWSRDELDAM
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
LPLLTARLDAAGQVQRFRPRYWKLLYFKQKGDKTWWDAVVTDENDAFVTVSLPDQQIFVR
HHHHHHHHCCCHHHHHHCCCCEEEEEEEECCCCCEECEEEECCCCEEEEEECCCCEEEEE
GRRSSFGERAHPGTRLMVRIGKVHPLNNEIQILDVMEQ
CCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCC
>Mature Secondary Structure 
SATSPLVQYPGPGCIVEFMQGNKPQIAWVQEEQSGKLRLLTQSKRETKLAAARVMPWAG
CCCCCCCCCCCCCHHHHHHCCCCCCEEEEEECCCCCEEEEECCHHHHHHHHHHCCCCCC
PQYGADKSRQEALELLNQHEERRNTRAAALDPLELWELAQGEVQAATAQWFAELLHESPD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
ADDIAAMGRVLLECKTHFKFQSPEFEIYDAEKVHARMTEQEARRKREQLASEGHDFLRAL
HHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WETHQKRRTPPCTPEDAGLAAEIEALLRKRIAEPDDHDSEQLWKQISKGLPDVPHLPLLL
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHH
AQAWGIVPAHHNFHLDRADYDRSPDWHAPHAQALADLRRRVLAARTEPCGIPFISIDSSS
HHHHCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCC
TRDIDDAFHIEPRADGGHRLRLAIACPALGWEFGSELDKAVMRRATSIYLPEGNLHMLPE
CCCCCCCEEECCCCCCCCEEEEEEECCHHCCHHHHHHHHHHHHHHHEEEECCCCCEECHH
ELGTDFFSLIGQQERPALVMEFDIAPAGQLEATTLKACWVQLAANLSYADCEAVLNGDPG
HHCCHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
WDAPDNPAAAFADQLKAGAALSRILLEQRVSCGAVVIERPDPKTTLTGTGADTQVEIEHD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEECCCCCCEEEEECC
SPTPASCLLVSEMMILANSGIALWAKDRDIALLHRTQDVGVPKEYAGVWDQPHDIARVVK
CCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCHHHHCCCCCCHHHHHHHH
ALSSAVLETAPRRHSGIGVPAYSPVTSPLRRYPDLVNVAQLIHYLGTGTPRWSRDELDAM
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
LPLLTARLDAAGQVQRFRPRYWKLLYFKQKGDKTWWDAVVTDENDAFVTVSLPDQQIFVR
HHHHHHHHCCCHHHHHHCCCCEEEEEEEECCCCCEECEEEECCCCEEEEEECCCCEEEEE
GRRSSFGERAHPGTRLMVRIGKVHPLNNEIQILDVMEQ
CCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]