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The map label for this gene is oxaA

Identifier: 78224744

GI number: 78224744

Start: 3995018

End: 3996628

Strand: Reverse

Name: oxaA

Synonym: Gmet_3561

Alternate gene names: 78224744

Gene position: 3996628-3995018 (Counterclockwise)

Preceding gene: 78224745

Following gene: 78224743

Centisome position: 99.98

GC content: 58.97

Gene sequence:

>1611_bases
ATGGAAAAAAGGGCTTTGATTGCAGTTATCCTCTCTATTGTATTCTTCTACGGGTACTCGGCCCTGTTCCCCCCGCCGAA
GAAGGAGGCTCCGGCGCCGTCCGCCCAGCAGGCGGTGACCGGTTCCCAGCCGGGAGCACCCCAGGCTTCTGTAGCGGCAG
TTCCGGCCCCTTCACCTGTGCCCGCTGCAGCGGTTAAGGCCCAGCAGAAGGAGATAGCCGTCGAGACGCCGGACTATACG
GCGGTCTTTTCGACTCAAGGGGGTAGTCTGACCCGCCTTGTCCTGAAAAAGTACCGCGAAACCGCTGACCTCACCGGCAA
ACATGTCACCTTGGTGGACGAGCGCGACCCGTCCGCTTATACCCTCTCCACCCGTGCCGCCGGCATTGGTCTCGATCCGT
CTGCCCTCTTTGTGTCGAGCGCCGACTCCCTGACCGTGGAGGCAGGGGAGGAGAAGAAGGAACTTGCCTTCACCTGGATA
TCGCCTGCCGGCGTCACGGTCCGCAAGATTTACACTTTCCAGGGTGGCAACTACGGCATCGACATGGTCTACCAGACTGC
CAATTCCGGCACGGCCCGGGTCGGCGCCGCCTTCCAGACGGTCATGACCTATCCGGCGGTTCCCCGGGTCAAGGAGAGCC
GGCTTGAGACGTTCGGACCGGTGACCTTTGCCCAGGACAAGCTTACGGAGGAGAAGGTCAAGGACCTGGTCGGGCAGGGG
AAGAGCTACAGTGCACCTCTCTGGAGCGGTTTTGCCGACAAGTATTTCCTCTCGGCCGTCGTGGGGCAGGGGGGGAGCAT
CGCCACGGCCGCTGTCCGCAGCACCCCCCGGGGGATGCTTGAGGACACCATCACCGCACCGGAAACTTCTCTGAATCCCG
GCGAGTCGAAATCCGTCGCCTATCGCCTCTACTTCGGTCCCAAGGATCTGGATATCCTCAAGGCACAGGGGAACAGCCTG
GAGCGGGCCATCGACCTGGGCTGGTTCGCAATGCTGGCCAAACCGCTTCTCCACAGCCTCAAGTTCTTCTACAAGTACGT
CCACAACTATGGCATCGCCATTATCATTATCACGGTGATCCTGAAGATCATCTTCTATCCCCTGACCCACTCCAGCTACA
AGTCCATGAAGCAGATGCAGAAGCTTCAGCCGAAGATGCAGGAGGTGCGGGAAAAGTACAAGAATGACCGCGATGCCATG
AACAAGGCGATCATGGAACTCTACCAGACCCACAAGGTGAACCCCGTGGGTGGTTGCCTCCCGATGCTCGTCCAGATCCC
GGTCTTCTTCGCCCTCTACAAGGCCCTCATGTTCTCCATTGAACTGCGCCACGCGCCGTTCATGCTTTGGATCCAGGATC
TCGCCGGCAAGGATCCTTATTATGTGACTCCCATCATCATGGGGATCACCATGGTCATCCAGCAGAAGATGACGCCGTCC
CAAATGGACCCCATGCAGCAGAAGATGATGATGGCCCTGCCGGTGGTCTTCACCTTCATGTTCCTGAACTTCCCGTCGGG
ACTCGTCCTCTACTGGCTCGTGAACAACGTTCTGACCATTATCCAGCAATCCTACATCAACAAGAGCATCGCCGCGGCCG
AGGCCAAGTAG

Upstream 100 bases:

>100_bases
CTCAAAGGGCTGTGGTACAGTGCCGTCCGGATCATGAAATGTCATCCGTACCACCCCGGTGGCTACGACCCCGTCAAGTA
ACCATCCATCAGGAGCTGAC

Downstream 100 bases:

>100_bases
GGACACGATGTACCTGGAAGATACCATAGCGGCCATCGGCACGCCGGTGGGGGAGGGGGGGATCGGCATCATCCGCGTGA
GCGGTCCCGATGTCCCCGCC

Product: protein translocase subunit yidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 536

Protein sequence:

>536_residues
MEKRALIAVILSIVFFYGYSALFPPPKKEAPAPSAQQAVTGSQPGAPQASVAAVPAPSPVPAAAVKAQQKEIAVETPDYT
AVFSTQGGSLTRLVLKKYRETADLTGKHVTLVDERDPSAYTLSTRAAGIGLDPSALFVSSADSLTVEAGEEKKELAFTWI
SPAGVTVRKIYTFQGGNYGIDMVYQTANSGTARVGAAFQTVMTYPAVPRVKESRLETFGPVTFAQDKLTEEKVKDLVGQG
KSYSAPLWSGFADKYFLSAVVGQGGSIATAAVRSTPRGMLEDTITAPETSLNPGESKSVAYRLYFGPKDLDILKAQGNSL
ERAIDLGWFAMLAKPLLHSLKFFYKYVHNYGIAIIIITVILKIIFYPLTHSSYKSMKQMQKLQPKMQEVREKYKNDRDAM
NKAIMELYQTHKVNPVGGCLPMLVQIPVFFALYKALMFSIELRHAPFMLWIQDLAGKDPYYVTPIIMGITMVIQQKMTPS
QMDPMQQKMMMALPVVFTFMFLNFPSGLVLYWLVNNVLTIIQQSYINKSIAAAEAK

Sequences:

>Translated_536_residues
MEKRALIAVILSIVFFYGYSALFPPPKKEAPAPSAQQAVTGSQPGAPQASVAAVPAPSPVPAAAVKAQQKEIAVETPDYT
AVFSTQGGSLTRLVLKKYRETADLTGKHVTLVDERDPSAYTLSTRAAGIGLDPSALFVSSADSLTVEAGEEKKELAFTWI
SPAGVTVRKIYTFQGGNYGIDMVYQTANSGTARVGAAFQTVMTYPAVPRVKESRLETFGPVTFAQDKLTEEKVKDLVGQG
KSYSAPLWSGFADKYFLSAVVGQGGSIATAAVRSTPRGMLEDTITAPETSLNPGESKSVAYRLYFGPKDLDILKAQGNSL
ERAIDLGWFAMLAKPLLHSLKFFYKYVHNYGIAIIIITVILKIIFYPLTHSSYKSMKQMQKLQPKMQEVREKYKNDRDAM
NKAIMELYQTHKVNPVGGCLPMLVQIPVFFALYKALMFSIELRHAPFMLWIQDLAGKDPYYVTPIIMGITMVIQQKMTPS
QMDPMQQKMMMALPVVFTFMFLNFPSGLVLYWLVNNVLTIIQQSYINKSIAAAEAK
>Mature_536_residues
MEKRALIAVILSIVFFYGYSALFPPPKKEAPAPSAQQAVTGSQPGAPQASVAAVPAPSPVPAAAVKAQQKEIAVETPDYT
AVFSTQGGSLTRLVLKKYRETADLTGKHVTLVDERDPSAYTLSTRAAGIGLDPSALFVSSADSLTVEAGEEKKELAFTWI
SPAGVTVRKIYTFQGGNYGIDMVYQTANSGTARVGAAFQTVMTYPAVPRVKESRLETFGPVTFAQDKLTEEKVKDLVGQG
KSYSAPLWSGFADKYFLSAVVGQGGSIATAAVRSTPRGMLEDTITAPETSLNPGESKSVAYRLYFGPKDLDILKAQGNSL
ERAIDLGWFAMLAKPLLHSLKFFYKYVHNYGIAIIIITVILKIIFYPLTHSSYKSMKQMQKLQPKMQEVREKYKNDRDAM
NKAIMELYQTHKVNPVGGCLPMLVQIPVFFALYKALMFSIELRHAPFMLWIQDLAGKDPYYVTPIIMGITMVIQQKMTPS
QMDPMQQKMMMALPVVFTFMFLNFPSGLVLYWLVNNVLTIIQQSYINKSIAAAEAK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=494, Percent_Identity=33.6032388663968, Blast_Score=281, Evalue=8e-77,
Organism=Drosophila melanogaster, GI24662345, Length=301, Percent_Identity=26.9102990033223, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356443, Length=301, Percent_Identity=26.9102990033223, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_GEOMG (Q39PQ8)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_386491.1
- ProteinModelPortal:   Q39PQ8
- STRING:   Q39PQ8
- GeneID:   3739860
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_3561
- NMPDR:   fig|269799.3.peg.3529
- eggNOG:   COG0706
- HOGENOM:   HBG507812
- OMA:   VELYREP
- PhylomeDB:   Q39PQ8
- ProtClustDB:   CLSK829298
- BioCyc:   GMET269799:GMET_3561-MONOMER
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 58996; Mature: 58996

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x160bcfd0)-; HASH(0x14c9c2f4)-; HASH(0x15dc4ed8)-; HASH(0x15a22248)-; HASH(0x15e96a54)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRALIAVILSIVFFYGYSALFPPPKKEAPAPSAQQAVTGSQPGAPQASVAAVPAPSPV
CCCHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEECCCCCCC
PAAAVKAQQKEIAVETPDYTAVFSTQGGSLTRLVLKKYRETADLTGKHVTLVDERDPSAY
CHHHHHHHHHHEEEECCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEE
TLSTRAAGIGLDPSALFVSSADSLTVEAGEEKKELAFTWISPAGVTVRKIYTFQGGNYGI
EEECCCCCCCCCCHHHEEECCCCEEEECCCCCCEEEEEEECCCCCEEEEEEEECCCCCCE
DMVYQTANSGTARVGAAFQTVMTYPAVPRVKESRLETFGPVTFAQDKLTEEKVKDLVGQG
EEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
KSYSAPLWSGFADKYFLSAVVGQGGSIATAAVRSTPRGMLEDTITAPETSLNPGESKSVA
CCCCCCHHCCHHHHHHHHHHHCCCCCEEHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCEE
YRLYFGPKDLDILKAQGNSLERAIDLGWFAMLAKPLLHSLKFFYKYVHNYGIAIIIITVI
EEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LKIIFYPLTHSSYKSMKQMQKLQPKMQEVREKYKNDRDAMNKAIMELYQTHKVNPVGGCL
HHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHH
PMLVQIPVFFALYKALMFSIELRHAPFMLWIQDLAGKDPYYVTPIIMGITMVIQQKMTPS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCC
QMDPMQQKMMMALPVVFTFMFLNFPSGLVLYWLVNNVLTIIQQSYINKSIAAAEAK
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MEKRALIAVILSIVFFYGYSALFPPPKKEAPAPSAQQAVTGSQPGAPQASVAAVPAPSPV
CCCHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEECCCCCCC
PAAAVKAQQKEIAVETPDYTAVFSTQGGSLTRLVLKKYRETADLTGKHVTLVDERDPSAY
CHHHHHHHHHHEEEECCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEE
TLSTRAAGIGLDPSALFVSSADSLTVEAGEEKKELAFTWISPAGVTVRKIYTFQGGNYGI
EEECCCCCCCCCCHHHEEECCCCEEEECCCCCCEEEEEEECCCCCEEEEEEEECCCCCCE
DMVYQTANSGTARVGAAFQTVMTYPAVPRVKESRLETFGPVTFAQDKLTEEKVKDLVGQG
EEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
KSYSAPLWSGFADKYFLSAVVGQGGSIATAAVRSTPRGMLEDTITAPETSLNPGESKSVA
CCCCCCHHCCHHHHHHHHHHHCCCCCEEHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCEE
YRLYFGPKDLDILKAQGNSLERAIDLGWFAMLAKPLLHSLKFFYKYVHNYGIAIIIITVI
EEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LKIIFYPLTHSSYKSMKQMQKLQPKMQEVREKYKNDRDAMNKAIMELYQTHKVNPVGGCL
HHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHH
PMLVQIPVFFALYKALMFSIELRHAPFMLWIQDLAGKDPYYVTPIIMGITMVIQQKMTPS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCC
QMDPMQQKMMMALPVVFTFMFLNFPSGLVLYWLVNNVLTIIQQSYINKSIAAAEAK
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA