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The map label for this gene is 78224688

Identifier: 78224688

GI number: 78224688

Start: 3935263

End: 3936246

Strand: Direct

Name: 78224688

Synonym: Gmet_3505

Alternate gene names: NA

Gene position: 3935263-3936246 (Clockwise)

Preceding gene: 78224687

Following gene: 78224689

Centisome position: 98.45

GC content: 68.29

Gene sequence:

>984_bases
GTGTCGCTGCATCCCGCGGACTTCATTGAAAAACCGCCGCGCTTCCCGGTCGTCGACGGCCACGTGGACCTCGTCTACGA
CCTGATGCGCCGTCACCCCGGAATCCCCTTCGAGCAGGTGGCAGACGGGCAGGTAACCGCCCAATCACTAAAGAAGGGAG
GAGTGTGGGTGCTGGTGGCTGCCCTCTACTGCGCCGACAGCCACAACGGTCCCGCGAGCGCCGCGCGGGAGATGCGGCGG
CTCCACGACTACGCCTGCCGATACCTGGAATGGTTCGCGCTACTCCGGAGTCCCGGGGAGATGGCGGCCGCCCTCGGAGG
AAGCGGCCCCCCCGGCATCGTCTTTCTCGTCGAAAATGCCGACGCCCTGCTGGAGCTGGACCTGGACGAGGTACGGCGTT
GGGGAGTGAGGGCCGTGGGGCTGACCCATGCCGGCAGAAACCGGCTGGCCGACGGCAACGGCGTTACCGACCCGAAGGGG
CTGACCGCTGCGGGGAAAAGTCTGGTGAGGAGCATCGCCGGCGCTGGCCTCATCCTCGACGTGGCTCACCTGGCCGAGCC
TGGTTTCCGGGAGGTGGCTTCCCTCGTCACTGGCCCCCTCATCTCCTCCCACACGGGGCTTCGCTCCTTCTGCGACCGCC
CCCGCAACCTCTCCGATCCCCAGGTGGCCGAGATTGCCCGCCGGGGAGGGGTGGTGGGAATTTCCGCCGCTCCCGAGATG
CTTGTTCCCGGAGGAACGGCGACCCTCGACGACCTCTTCCGCCAGGTCGATCACGTGGTTCAGCGGCATGGACCGGAGGC
GGTCGGCATCGGGAGCGATTTCGGCGGGTTCGACGACACGGCAAAGGGAGCGGAGGACCACGGCGGACTTCCCCTCCTGG
CGGAGCGCCTCCTGGGGGCGGGCTATCCCGCCGGGGCAGTGGGGCTCATCATGGGGGGAAACTGGTGCCGGATCTACGGG
GGAATTCCCGGCGGACCGGCATGA

Upstream 100 bases:

>100_bases
CCGGCATAGGAAATGATCGCTGAAGTTTTCCGAGCGGGTTGACGCCATGGTCTGCCCGCTCTTTTTCGTTCCGCTGCTGC
GGAACCGATGAGGAGCGATT

Downstream 100 bases:

>100_bases
GAGTCGCTGTTTTTATCTTTTCGGATGCCTAACAGACTGCCGGACAAGAGCTTTTTGCCCTGGAGCCGATTGTTCATTGA
CACGCCCGACATCCCACAAT

Product: peptidase M19, renal dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MSLHPADFIEKPPRFPVVDGHVDLVYDLMRRHPGIPFEQVADGQVTAQSLKKGGVWVLVAALYCADSHNGPASAAREMRR
LHDYACRYLEWFALLRSPGEMAAALGGSGPPGIVFLVENADALLELDLDEVRRWGVRAVGLTHAGRNRLADGNGVTDPKG
LTAAGKSLVRSIAGAGLILDVAHLAEPGFREVASLVTGPLISSHTGLRSFCDRPRNLSDPQVAEIARRGGVVGISAAPEM
LVPGGTATLDDLFRQVDHVVQRHGPEAVGIGSDFGGFDDTAKGAEDHGGLPLLAERLLGAGYPAGAVGLIMGGNWCRIYG
GIPGGPA

Sequences:

>Translated_327_residues
MSLHPADFIEKPPRFPVVDGHVDLVYDLMRRHPGIPFEQVADGQVTAQSLKKGGVWVLVAALYCADSHNGPASAAREMRR
LHDYACRYLEWFALLRSPGEMAAALGGSGPPGIVFLVENADALLELDLDEVRRWGVRAVGLTHAGRNRLADGNGVTDPKG
LTAAGKSLVRSIAGAGLILDVAHLAEPGFREVASLVTGPLISSHTGLRSFCDRPRNLSDPQVAEIARRGGVVGISAAPEM
LVPGGTATLDDLFRQVDHVVQRHGPEAVGIGSDFGGFDDTAKGAEDHGGLPLLAERLLGAGYPAGAVGLIMGGNWCRIYG
GIPGGPA
>Mature_326_residues
SLHPADFIEKPPRFPVVDGHVDLVYDLMRRHPGIPFEQVADGQVTAQSLKKGGVWVLVAALYCADSHNGPASAAREMRRL
HDYACRYLEWFALLRSPGEMAAALGGSGPPGIVFLVENADALLELDLDEVRRWGVRAVGLTHAGRNRLADGNGVTDPKGL
TAAGKSLVRSIAGAGLILDVAHLAEPGFREVASLVTGPLISSHTGLRSFCDRPRNLSDPQVAEIARRGGVVGISAAPEML
VPGGTATLDDLFRQVDHVVQRHGPEAVGIGSDFGGFDDTAKGAEDHGGLPLLAERLLGAGYPAGAVGLIMGGNWCRIYGG
IPGGPA

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI193211608, Length=323, Percent_Identity=24.7678018575851, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI193211610, Length=323, Percent_Identity=24.7678018575851, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI11641269, Length=323, Percent_Identity=24.7678018575851, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI189458885, Length=331, Percent_Identity=24.1691842900302, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4758190, Length=331, Percent_Identity=24.1691842900302, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI221475880, Length=190, Percent_Identity=28.4210526315789, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI281362638, Length=195, Percent_Identity=29.2307692307692, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281362636, Length=195, Percent_Identity=29.2307692307692, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI161083233, Length=185, Percent_Identity=29.1891891891892, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 34319; Mature: 34187

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLHPADFIEKPPRFPVVDGHVDLVYDLMRRHPGIPFEQVADGQVTAQSLKKGGVWVLVA
CCCCCHHHHCCCCCCCEECCHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHCCCHHHHHH
ALYCADSHNGPASAAREMRRLHDYACRYLEWFALLRSPGEMAAALGGSGPPGIVFLVENA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEEEECC
DALLELDLDEVRRWGVRAVGLTHAGRNRLADGNGVTDPKGLTAAGKSLVRSIAGAGLILD
CCEEECCHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHH
VAHLAEPGFREVASLVTGPLISSHTGLRSFCDRPRNLSDPQVAEIARRGGVVGISAAPEM
HHHHCCCCHHHHHHHHHCCHHHCCCHHHHHHCCCCCCCCHHHHHHHHHCCEEEECCCCCE
LVPGGTATLDDLFRQVDHVVQRHGPEAVGIGSDFGGFDDTAKGAEDHGGLPLLAERLLGA
ECCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCC
GYPAGAVGLIMGGNWCRIYGGIPGGPA
CCCCCCEEEEECCCEEEEECCCCCCCC
>Mature Secondary Structure 
SLHPADFIEKPPRFPVVDGHVDLVYDLMRRHPGIPFEQVADGQVTAQSLKKGGVWVLVA
CCCCHHHHCCCCCCCEECCHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHCCCHHHHHH
ALYCADSHNGPASAAREMRRLHDYACRYLEWFALLRSPGEMAAALGGSGPPGIVFLVENA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEEEECC
DALLELDLDEVRRWGVRAVGLTHAGRNRLADGNGVTDPKGLTAAGKSLVRSIAGAGLILD
CCEEECCHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHH
VAHLAEPGFREVASLVTGPLISSHTGLRSFCDRPRNLSDPQVAEIARRGGVVGISAAPEM
HHHHCCCCHHHHHHHHHCCHHHCCCHHHHHHCCCCCCCCHHHHHHHHHCCEEEECCCCCE
LVPGGTATLDDLFRQVDHVVQRHGPEAVGIGSDFGGFDDTAKGAEDHGGLPLLAERLLGA
ECCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCC
GYPAGAVGLIMGGNWCRIYGGIPGGPA
CCCCCCEEEEECCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]