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The map label for this gene is iorA [H]

Identifier: 78224673

GI number: 78224673

Start: 3919694

End: 3920155

Strand: Reverse

Name: iorA [H]

Synonym: Gmet_3490

Alternate gene names: 78224673

Gene position: 3920155-3919694 (Counterclockwise)

Preceding gene: 78224674

Following gene: 78224672

Centisome position: 98.07

GC content: 62.77

Gene sequence:

>462_bases
ATGAAAAGGATCACGTTCAAGGTCAACGGCGTTACGCACTCGTTCGCAGGGGAACCGGAGATGCCGCTTCTGTGGTATCT
CCGGGACGAACTGCACCTGACCGGCACCAAGTACGGCTGCGGCAAGGGGCTCTGCGGGGCTTGCACGGTGCAGATCAACG
GGGAGGCGACGCGCAGCTGCATAACGACCATGAAGAGCGTGGCGGGGAAGAAGATCGTCACCATCGAGGGGTTGAGCGCC
CGGGGAGACCACCCGCTGCAAAAGGCCTGGCAGGAGCTGAACGTGCCCCAGTGCGGCTACTGCCAGAGCGGCCAGATTAT
GCAGGCCGCGGCTCTTCTCAAGGGAAAGCCCCATCCGACCGATCAGGAGATCGACGAGGCGATGGGAGGCAATATCTGCC
GCTGCGGAACCTACGAGCGGATCCGCCAGGGGATCAAACGGGCAGCGGAGGTGAAGCCATGA

Upstream 100 bases:

>100_bases
CCGCTCGAGGGATCAAAACCGCCATAACGTGAAGAATACTTGTCGCCATGAGCTAAGGAGAATTGTGCCACCGGAGGTGC
CGGCAACAGGGGAGGAGTCC

Downstream 100 bases:

>100_bases
GCGCCGTGGTTCGCATGAGCCGCCGCGGATTTCTCAAGACGACGTTTTCGGCGGGGGCCCTGATCCTCTGCGCCCGTGTT
CTTCCCGGCGGAGCCCTCGA

Product: ferredoxin:(2Fe-2S)-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MKRITFKVNGVTHSFAGEPEMPLLWYLRDELHLTGTKYGCGKGLCGACTVQINGEATRSCITTMKSVAGKKIVTIEGLSA
RGDHPLQKAWQELNVPQCGYCQSGQIMQAAALLKGKPHPTDQEIDEAMGGNICRCGTYERIRQGIKRAAEVKP

Sequences:

>Translated_153_residues
MKRITFKVNGVTHSFAGEPEMPLLWYLRDELHLTGTKYGCGKGLCGACTVQINGEATRSCITTMKSVAGKKIVTIEGLSA
RGDHPLQKAWQELNVPQCGYCQSGQIMQAAALLKGKPHPTDQEIDEAMGGNICRCGTYERIRQGIKRAAEVKP
>Mature_153_residues
MKRITFKVNGVTHSFAGEPEMPLLWYLRDELHLTGTKYGCGKGLCGACTVQINGEATRSCITTMKSVAGKKIVTIEGLSA
RGDHPLQKAWQELNVPQCGYCQSGQIMQAAALLKGKPHPTDQEIDEAMGGNICRCGTYERIRQGIKRAAEVKP

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=161, Percent_Identity=37.2670807453416, Blast_Score=80, Evalue=6e-16,
Organism=Homo sapiens, GI71773480, Length=136, Percent_Identity=39.7058823529412, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1786480, Length=166, Percent_Identity=43.3734939759036, Blast_Score=120, Evalue=3e-29,
Organism=Escherichia coli, GI1789232, Length=141, Percent_Identity=37.5886524822695, Blast_Score=81, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17540638, Length=159, Percent_Identity=38.3647798742138, Blast_Score=106, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=35.7142857142857, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI32566215, Length=154, Percent_Identity=35.7142857142857, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=35.1851851851852, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=35.1851851851852, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI17737937, Length=157, Percent_Identity=36.9426751592357, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24647201, Length=155, Percent_Identity=34.1935483870968, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24647193, Length=163, Percent_Identity=34.9693251533742, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24647199, Length=154, Percent_Identity=35.0649350649351, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16694; Mature: 16694

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRITFKVNGVTHSFAGEPEMPLLWYLRDELHLTGTKYGCGKGLCGACTVQINGEATRSC
CCEEEEEECCEEECCCCCCCCCEEEEEECCEEECCCCCCCCCCCCEEEEEEECCHHHHHH
ITTMKSVAGKKIVTIEGLSARGDHPLQKAWQELNVPQCGYCQSGQIMQAAALLKGKPHPT
HHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCC
DQEIDEAMGGNICRCGTYERIRQGIKRAAEVKP
HHHHHHHHCCCEEECCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRITFKVNGVTHSFAGEPEMPLLWYLRDELHLTGTKYGCGKGLCGACTVQINGEATRSC
CCEEEEEECCEEECCCCCCCCCEEEEEECCEEECCCCCCCCCCCCEEEEEEECCHHHHHH
ITTMKSVAGKKIVTIEGLSARGDHPLQKAWQELNVPQCGYCQSGQIMQAAALLKGKPHPT
HHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCC
DQEIDEAMGGNICRCGTYERIRQGIKRAAEVKP
HHHHHHHHCCCEEECCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]