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The map label for this gene is erfK [H]

Identifier: 78224668

GI number: 78224668

Start: 3913300

End: 3914748

Strand: Direct

Name: erfK [H]

Synonym: Gmet_3485

Alternate gene names: 78224668

Gene position: 3913300-3914748 (Clockwise)

Preceding gene: 78224667

Following gene: 78224669

Centisome position: 97.9

GC content: 59.08

Gene sequence:

>1449_bases
ATGGGGCGGAAAGCCTATAGGGTCTCCCTGAGACAGCCGGGTTGCCGAAATATCACGCGATATTTGGTCCCGGCTTTTTT
GTGTCTTGACGCGGAACTTACCCATTCTCGAGAAAGGTACCGAACTCAATCCATGTACCGAATCGCTGACCTGCCCCTCT
CTACCGCCTGTTTTCGCCTGATCGCTCTAGGGGTATGTATCCTATCCCTTCAAGGATGCGCTGTACTCAGGGGTGCCCAG
GAGCAATCATCGCTTGCGCCAGGCCATCTTGCCGCGGAGATCGAACGAAATGACTTTCCCGTTGCCAATGGCGACGACGT
CATTGGCCGGCTTGCCGTCCTCAGACTTGAACAGGGGGATACGCTCCCGGATATTGCGAGACATTTCGGTCTGGGGATCA
CGGCACTCAGCGCCGCCAATCCGGGCATGGATGTCTGGGCGCCCGAGGCCGGAAAACCGGTCATCCTGCCCCTGAGCTTT
GTCCTGCCGGACACCCCGAGACGAGGGATTGTGGTCAACGTCGCCACAATGAGGCTCTTTCAGTACAAGGGCGATGGCGC
CTCCCTGGCGGTATCCACCTACCCCGTCGGCGTCGGCACCAAGGAGCGCCCCACCCCCACCGGCCCAACGCGGGTGTATC
GCAAGGCGGCCCGGCCGACCTGGCATGTGCCTGCTTCAATTGCCGAGGACCATCGAAAGAAGGGGGATCCGCTCCCCCCG
GAAGTTCCGCCGGGGCCGGAGAATCCCCTGGGGGAATACGCTCTCTACCTGAGCAAACCGGGGTATCTGATCCATGGCAC
GAACAAGCCGGCCAGCATCGGGCTTAAGGCAACCAATGGCTGTATGAGGCTCTATCCGGAAAACATCGAGGTGCTCTATA
ACGACACGCCGGTCAACACCCCGGTGGCCATTGTCAACCAACCCTACCTCATCGGTCAACGGGACGGGGTGCTTTACCTG
GAAGCCCATACCCCGCTGGAAGACGCAGGCACTCTCGAACTGACGAAGGTGTATGAAAAGTTGAGAGCCATTGAAAAGAA
AACAGGCCGTGCGCTTGACTGGACAAAAATCAGAAAAGTTCAGGCCGAGGCCCGGGGGATTCCGGTTCCCATCCTCGAAC
TGCGCCAGGGAAGTGAAAAAGGGATTCCGCAAACCATGGAAGTCGGGCACCCCGACACACTGCACGGCAGACCGGAAATA
CCGGACCTGAAACCGGATGCCTGGTATGTTCTGGCTGCCGATGTGCGTAACGAGCTTGAGGCCCGGAGGATTGCCGCCAT
CATCAACCACCAGGGCCCTCCGATACCGGCACGGGTCTTGGCAAAGAACAACGCCTACCGTGTCATCGCCGGCCCGTTCG
CTGATGGCAGTAGGGCCAGGGATGCGGCCAAACGCCTGAAGATCGATTTGGAAATCGACGGCATATTGATTGATCCTGCT
GGGAAGTAG

Upstream 100 bases:

>100_bases
CCGACAAGGAGTGCGTCTCTGACGTGGCGGTGCCTGTGGGCGCCGGAAAACTGCAACAAAATAGTTGGTGGTAGACGATA
ATACTAAACCATTCGCGAGA

Downstream 100 bases:

>100_bases
ACAGCCCCTCTTCCTGGCTGGGCAACCTAGAGAGAAAGGAGGTGATTAGCGATGAAAGGGATTCTCTTGCTGATCGCAAT
GCTGCTCGTTCTCCCTGTCA

Product: ErfK/YbiS/YcfS/YnhG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MGRKAYRVSLRQPGCRNITRYLVPAFLCLDAELTHSRERYRTQSMYRIADLPLSTACFRLIALGVCILSLQGCAVLRGAQ
EQSSLAPGHLAAEIERNDFPVANGDDVIGRLAVLRLEQGDTLPDIARHFGLGITALSAANPGMDVWAPEAGKPVILPLSF
VLPDTPRRGIVVNVATMRLFQYKGDGASLAVSTYPVGVGTKERPTPTGPTRVYRKAARPTWHVPASIAEDHRKKGDPLPP
EVPPGPENPLGEYALYLSKPGYLIHGTNKPASIGLKATNGCMRLYPENIEVLYNDTPVNTPVAIVNQPYLIGQRDGVLYL
EAHTPLEDAGTLELTKVYEKLRAIEKKTGRALDWTKIRKVQAEARGIPVPILELRQGSEKGIPQTMEVGHPDTLHGRPEI
PDLKPDAWYVLAADVRNELEARRIAAIINHQGPPIPARVLAKNNAYRVIAGPFADGSRARDAAKRLKIDLEIDGILIDPA
GK

Sequences:

>Translated_482_residues
MGRKAYRVSLRQPGCRNITRYLVPAFLCLDAELTHSRERYRTQSMYRIADLPLSTACFRLIALGVCILSLQGCAVLRGAQ
EQSSLAPGHLAAEIERNDFPVANGDDVIGRLAVLRLEQGDTLPDIARHFGLGITALSAANPGMDVWAPEAGKPVILPLSF
VLPDTPRRGIVVNVATMRLFQYKGDGASLAVSTYPVGVGTKERPTPTGPTRVYRKAARPTWHVPASIAEDHRKKGDPLPP
EVPPGPENPLGEYALYLSKPGYLIHGTNKPASIGLKATNGCMRLYPENIEVLYNDTPVNTPVAIVNQPYLIGQRDGVLYL
EAHTPLEDAGTLELTKVYEKLRAIEKKTGRALDWTKIRKVQAEARGIPVPILELRQGSEKGIPQTMEVGHPDTLHGRPEI
PDLKPDAWYVLAADVRNELEARRIAAIINHQGPPIPARVLAKNNAYRVIAGPFADGSRARDAAKRLKIDLEIDGILIDPA
GK
>Mature_481_residues
GRKAYRVSLRQPGCRNITRYLVPAFLCLDAELTHSRERYRTQSMYRIADLPLSTACFRLIALGVCILSLQGCAVLRGAQE
QSSLAPGHLAAEIERNDFPVANGDDVIGRLAVLRLEQGDTLPDIARHFGLGITALSAANPGMDVWAPEAGKPVILPLSFV
LPDTPRRGIVVNVATMRLFQYKGDGASLAVSTYPVGVGTKERPTPTGPTRVYRKAARPTWHVPASIAEDHRKKGDPLPPE
VPPGPENPLGEYALYLSKPGYLIHGTNKPASIGLKATNGCMRLYPENIEVLYNDTPVNTPVAIVNQPYLIGQRDGVLYLE
AHTPLEDAGTLELTKVYEKLRAIEKKTGRALDWTKIRKVQAEARGIPVPILELRQGSEKGIPQTMEVGHPDTLHGRPEIP
DLKPDAWYVLAADVRNELEARRIAAIINHQGPPIPARVLAKNNAYRVIAGPFADGSRARDAAKRLKIDLEIDGILIDPAG
K

Specific function: Responsible, at least in part, for anchoring of the major outer membrane lipoprotein (Lpp, also known as the Braun lipoprotein) to the peptidoglycan via a meso-diaminopimelyl-L-Lys- bond on the terminal residue of Lpp [H]

COG id: COG1376

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the YkuD family [H]

Homologues:

Organism=Escherichia coli, GI1788299, Length=228, Percent_Identity=39.9122807017544, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1787040, Length=231, Percent_Identity=38.5281385281385, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1787968, Length=281, Percent_Identity=34.5195729537367, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1787356, Length=217, Percent_Identity=38.7096774193548, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005490 [H]

Pfam domain/function: PF03734 YkuD [H]

EC number: NA

Molecular weight: Translated: 52663; Mature: 52532

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRKAYRVSLRQPGCRNITRYLVPAFLCLDAELTHSRERYRTQSMYRIADLPLSTACFRL
CCCCEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IALGVCILSLQGCAVLRGAQEQSSLAPGHLAAEIERNDFPVANGDDVIGRLAVLRLEQGD
HHHHHHHHHHCCHHHHCCCCHHHCCCCCCEEEEEECCCCCCCCCCHHHEEEEEEEECCCC
TLPDIARHFGLGITALSAANPGMDVWAPEAGKPVILPLSFVLPDTPRRGIVVNVATMRLF
CHHHHHHHHCCCEEEEECCCCCCEEECCCCCCEEEEEEEEECCCCCCCCEEEEEEEEEEE
QYKGDGASLAVSTYPVGVGTKERPTPTGPTRVYRKAARPTWHVPASIAEDHRKKGDPLPP
EECCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCC
EVPPGPENPLGEYALYLSKPGYLIHGTNKPASIGLKATNGCMRLYPENIEVLYNDTPVNT
CCCCCCCCCCCCEEEEEECCCEEEECCCCCCEEEEEECCCEEEECCCCEEEEECCCCCCC
PVAIVNQPYLIGQRDGVLYLEAHTPLEDAGTLELTKVYEKLRAIEKKTGRALDWTKIRKV
CEEEECCCEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHH
QAEARGIPVPILELRQGSEKGIPQTMEVGHPDTLHGRPEIPDLKPDAWYVLAADVRNELE
HHHHCCCCCCHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHH
ARRIAAIINHQGPPIPARVLAKNNAYRVIAGPFADGSRARDAAKRLKIDLEIDGILIDPA
HHHHHHHHCCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHEEEEEEECCEEECCC
GK
CC
>Mature Secondary Structure 
GRKAYRVSLRQPGCRNITRYLVPAFLCLDAELTHSRERYRTQSMYRIADLPLSTACFRL
CCCEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IALGVCILSLQGCAVLRGAQEQSSLAPGHLAAEIERNDFPVANGDDVIGRLAVLRLEQGD
HHHHHHHHHHCCHHHHCCCCHHHCCCCCCEEEEEECCCCCCCCCCHHHEEEEEEEECCCC
TLPDIARHFGLGITALSAANPGMDVWAPEAGKPVILPLSFVLPDTPRRGIVVNVATMRLF
CHHHHHHHHCCCEEEEECCCCCCEEECCCCCCEEEEEEEEECCCCCCCCEEEEEEEEEEE
QYKGDGASLAVSTYPVGVGTKERPTPTGPTRVYRKAARPTWHVPASIAEDHRKKGDPLPP
EECCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCC
EVPPGPENPLGEYALYLSKPGYLIHGTNKPASIGLKATNGCMRLYPENIEVLYNDTPVNT
CCCCCCCCCCCCEEEEEECCCEEEECCCCCCEEEEEECCCEEEECCCCEEEEECCCCCCC
PVAIVNQPYLIGQRDGVLYLEAHTPLEDAGTLELTKVYEKLRAIEKKTGRALDWTKIRKV
CEEEECCCEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHH
QAEARGIPVPILELRQGSEKGIPQTMEVGHPDTLHGRPEIPDLKPDAWYVLAADVRNELE
HHHHCCCCCCHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHH
ARRIAAIINHQGPPIPARVLAKNNAYRVIAGPFADGSRARDAAKRLKIDLEIDGILIDPA
HHHHHHHHCCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHEEEEEEECCEEECCC
GK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592411; 9097040; 9278503; 9298646 [H]