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The map label for this gene is ynfJ [C]

Identifier: 78224657

GI number: 78224657

Start: 3890950

End: 3892791

Strand: Direct

Name: ynfJ [C]

Synonym: Gmet_3470

Alternate gene names: 78224657

Gene position: 3890950-3892791 (Clockwise)

Preceding gene: 78224656

Following gene: 78224667

Centisome position: 97.34

GC content: 63.36

Gene sequence:

>1842_bases
ATGAAACAGCAACCCCCTCGACGAGCTCCGCTCTGGCCCACGCCATTGGTCCTGATCCACGACCTCCACCTGCTTCGCCG
GTTCGTTCGGCTACGGCGGAGTGTCCTGGCCCTCCTCTCCCGTCTGCGGATCAGCGAGAGCACCCTCATGGCAGTTCTGG
CCGTGGGGATAGGGCTCCTGGCGGGACTCTGCAACTACGCCTTCCGTTCGTGCATCGATTTTTTCCGCTGGCTCATCATC
GACAACGGTGCCCGACTGACCGGCTATTCCCCCGACACCTGGGACGCAAGCCGGCTCTGGGCGTTGGCCTTTCCCGTCAT
CGGCGCGACCATCATGCTCCCCCTCTTCATCTGGTACCGAGAGGACATGGCCTTCGGCTTCCCCCGTTTCCTTGAGAGGG
TCAACCTGAGGGGGGGACGACTTCCCCTGCGGCTCATGTTCACCAGGGGGATTTCGTCGGCCCTCACCATCGGCTCCGGC
GGCTCGGCCGGCCAGGAAGGCCCCATCGCCCAGATCGGCGGCACGGCCGGCTCCGTGGTTGGCCATCTGCTCGGCATGCC
GGAGGAACGGCTCAAGGTCCTGATCGGCTGCGGAGTTTCCGGCGGCGTGGCAGCCACCTTCAACGCCCCCCTCGCCGGCG
TCTTTTTTGCCCACGAAATTGTCCTTCTCTCCAGCTTCGAGCTTTCCTCTTTCACGAGCATCGTCATCTCATCCGGCATG
GCCACGGTCGTCTCCCGGGCCATGTACGGCGACATCCCCGCCTTTGACGTACCGGCCTACCAGCTCGTCCACCCCCTGGA
ACTGGTCTTGTATGCCCTGTTAGGGATCGTGTGCGGCTGCGTCGCGGCCCTCTTCATCACTGGCTATGGAAAAACCAGGG
AGTTTTTCGAGCAGCTCCGGGTGAATCCCCTCTGGAAGCCGCTGCTCGGGGGATTCCTCGCCGGCTGTGTCGGGGTCCTC
CTCCCCCAGGTCCAGGGAAACGGGTACGGATTCATTGAAAAGGCCGTCGGCAACGACGTGGGATGGCTCCTTGTCACGCT
CCTCATCGTCGGGAAGATGGCCGCCACCTGCGTCACGATCGGCTCGGGGCTGCCGGGGGGAACCTTCGCCCCGTCGCTTT
TCATAGGGTCAGTGACCGGCATGAGTTTCGGTTTCCTGGCAAACCTCCTCTTTCCGCTCCATACCGCAACGCCGGGGGCC
TATGCCCTGGTGGGAATGGGGGCGTTCCTCGCCTCGGTCACCCATGCGCCCATGACCGGCATCTTCCTCCTGTTTGAGAT
GACCGGTTCCTACAAGGTTATCATTCCGATCATGCTTGCCTGCTCCATCGGCACTGCCGTGGCGCGCCATTTCCGCAAGG
ACGGCATCGACACCGCCGACCTTGCAGCCCGGGGGATCGACCTGAGAACGGGGCGCGAGGAGACGATACTGGAGAAGATC
CAGGTGAGGGGAGTCATGATGCACGATGCGGAGGTTCTCCCCGAATCGATGACCATCCGTGAGTTTCTGGAACGCGCCCA
TACCCCTCGCCAGCACACCTTTCCCCTGGTAGACGCCGGCGGCGGCCTGGCCGGCGTCGTCACGATCCATGACTTCCTGG
GCGTCGCCTTCGAACCGGACATCCTGGACAAGGTTCCCCTCGGGGAAATGGCCACCGACGACGTCATCACCGTGCAGGGC
GACGAAAGCCTCGCCGCTGCGCTCAGGAAGATGGACCTCACCCCCATCGAAGAACTGCCGGTTGTCGATTCCGGCAATGG
AAAGGTTATCGGGATTCTGTCGCGACGGGAAGTCATTGCCGCCTACAACCGGGCGATCGTGGAACGGACGTTCCGGGCGT
GA

Upstream 100 bases:

>100_bases
CTGCGGGAATACGGGGAATAGTCCGCGCCGCCGCGTTAGAACCGCGCTGGGAAAATCAGTTGCGCAATTCCCGTGGCGTC
AGTATAAAATCTGCGTGCCC

Downstream 100 bases:

>100_bases
GCCCCCTTCCGCCATAGCTCTCGGCATCACTTTCCCGACCTCATGCTCAAGGGGGATGTCCGGGCAAAGGTCATCTGTGG
CGAGATCAACGGCGTCCGGG

Product: Cl- channel, voltage gated

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 613; Mature: 613

Protein sequence:

>613_residues
MKQQPPRRAPLWPTPLVLIHDLHLLRRFVRLRRSVLALLSRLRISESTLMAVLAVGIGLLAGLCNYAFRSCIDFFRWLII
DNGARLTGYSPDTWDASRLWALAFPVIGATIMLPLFIWYREDMAFGFPRFLERVNLRGGRLPLRLMFTRGISSALTIGSG
GSAGQEGPIAQIGGTAGSVVGHLLGMPEERLKVLIGCGVSGGVAATFNAPLAGVFFAHEIVLLSSFELSSFTSIVISSGM
ATVVSRAMYGDIPAFDVPAYQLVHPLELVLYALLGIVCGCVAALFITGYGKTREFFEQLRVNPLWKPLLGGFLAGCVGVL
LPQVQGNGYGFIEKAVGNDVGWLLVTLLIVGKMAATCVTIGSGLPGGTFAPSLFIGSVTGMSFGFLANLLFPLHTATPGA
YALVGMGAFLASVTHAPMTGIFLLFEMTGSYKVIIPIMLACSIGTAVARHFRKDGIDTADLAARGIDLRTGREETILEKI
QVRGVMMHDAEVLPESMTIREFLERAHTPRQHTFPLVDAGGGLAGVVTIHDFLGVAFEPDILDKVPLGEMATDDVITVQG
DESLAAALRKMDLTPIEELPVVDSGNGKVIGILSRREVIAAYNRAIVERTFRA

Sequences:

>Translated_613_residues
MKQQPPRRAPLWPTPLVLIHDLHLLRRFVRLRRSVLALLSRLRISESTLMAVLAVGIGLLAGLCNYAFRSCIDFFRWLII
DNGARLTGYSPDTWDASRLWALAFPVIGATIMLPLFIWYREDMAFGFPRFLERVNLRGGRLPLRLMFTRGISSALTIGSG
GSAGQEGPIAQIGGTAGSVVGHLLGMPEERLKVLIGCGVSGGVAATFNAPLAGVFFAHEIVLLSSFELSSFTSIVISSGM
ATVVSRAMYGDIPAFDVPAYQLVHPLELVLYALLGIVCGCVAALFITGYGKTREFFEQLRVNPLWKPLLGGFLAGCVGVL
LPQVQGNGYGFIEKAVGNDVGWLLVTLLIVGKMAATCVTIGSGLPGGTFAPSLFIGSVTGMSFGFLANLLFPLHTATPGA
YALVGMGAFLASVTHAPMTGIFLLFEMTGSYKVIIPIMLACSIGTAVARHFRKDGIDTADLAARGIDLRTGREETILEKI
QVRGVMMHDAEVLPESMTIREFLERAHTPRQHTFPLVDAGGGLAGVVTIHDFLGVAFEPDILDKVPLGEMATDDVITVQG
DESLAAALRKMDLTPIEELPVVDSGNGKVIGILSRREVIAAYNRAIVERTFRA
>Mature_613_residues
MKQQPPRRAPLWPTPLVLIHDLHLLRRFVRLRRSVLALLSRLRISESTLMAVLAVGIGLLAGLCNYAFRSCIDFFRWLII
DNGARLTGYSPDTWDASRLWALAFPVIGATIMLPLFIWYREDMAFGFPRFLERVNLRGGRLPLRLMFTRGISSALTIGSG
GSAGQEGPIAQIGGTAGSVVGHLLGMPEERLKVLIGCGVSGGVAATFNAPLAGVFFAHEIVLLSSFELSSFTSIVISSGM
ATVVSRAMYGDIPAFDVPAYQLVHPLELVLYALLGIVCGCVAALFITGYGKTREFFEQLRVNPLWKPLLGGFLAGCVGVL
LPQVQGNGYGFIEKAVGNDVGWLLVTLLIVGKMAATCVTIGSGLPGGTFAPSLFIGSVTGMSFGFLANLLFPLHTATPGA
YALVGMGAFLASVTHAPMTGIFLLFEMTGSYKVIIPIMLACSIGTAVARHFRKDGIDTADLAARGIDLRTGREETILEKI
QVRGVMMHDAEVLPESMTIREFLERAHTPRQHTFPLVDAGGGLAGVVTIHDFLGVAFEPDILDKVPLGEMATDDVITVQG
DESLAAALRKMDLTPIEELPVVDSGNGKVIGILSRREVIAAYNRAIVERTFRA

Specific function: Unknown

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Homo sapiens, GI119433677, Length=428, Percent_Identity=23.3644859813084, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI55770840, Length=396, Percent_Identity=23.7373737373737, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI55770838, Length=555, Percent_Identity=22.8828828828829, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI153252026, Length=390, Percent_Identity=23.3333333333333, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI87081943, Length=407, Percent_Identity=27.5184275184275, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1786350, Length=293, Percent_Identity=32.4232081911263, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17532615, Length=540, Percent_Identity=23.3333333333333, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71980828, Length=454, Percent_Identity=23.7885462555066, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71980824, Length=454, Percent_Identity=23.7885462555066, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24665008, Length=542, Percent_Identity=23.0627306273063, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 65912; Mature: 65912

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQQPPRRAPLWPTPLVLIHDLHLLRRFVRLRRSVLALLSRLRISESTLMAVLAVGIGLL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AGLCNYAFRSCIDFFRWLIIDNGARLTGYSPDTWDASRLWALAFPVIGATIMLPLFIWYR
HHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EDMAFGFPRFLERVNLRGGRLPLRLMFTRGISSALTIGSGGSAGQEGPIAQIGGTAGSVV
HHHHCCCHHHHHHHCCCCCCCCEEEHHHHCCCHHEEECCCCCCCCCCCCHHCCCCHHHHH
GHLLGMPEERLKVLIGCGVSGGVAATFNAPLAGVFFAHEIVLLSSFELSSFTSIVISSGM
HHHHCCCHHHHHEEEECCCCCCEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCH
ATVVSRAMYGDIPAFDVPAYQLVHPLELVLYALLGIVCGCVAALFITGYGKTREFFEQLR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
VNPLWKPLLGGFLAGCVGVLLPQVQGNGYGFIEKAVGNDVGWLLVTLLIVGKMAATCVTI
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GSGLPGGTFAPSLFIGSVTGMSFGFLANLLFPLHTATPGAYALVGMGAFLASVTHAPMTG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHH
IFLLFEMTGSYKVIIPIMLACSIGTAVARHFRKDGIDTADLAARGIDLRTGREETILEKI
HEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHH
QVRGVMMHDAEVLPESMTIREFLERAHTPRQHTFPLVDAGGGLAGVVTIHDFLGVAFEPD
HHHHEEEECHHHCCCHHHHHHHHHHHCCCCCCCCCEEECCCCEEHHHHHHHHHCCCCCCC
ILDKVPLGEMATDDVITVQGDESLAAALRKMDLTPIEELPVVDSGNGKVIGILSRREVIA
HHCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCHHHCCCEECCCCCEEEEECHHHHHH
AYNRAIVERTFRA
HHHHHHHHHHHCC
>Mature Secondary Structure
MKQQPPRRAPLWPTPLVLIHDLHLLRRFVRLRRSVLALLSRLRISESTLMAVLAVGIGLL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AGLCNYAFRSCIDFFRWLIIDNGARLTGYSPDTWDASRLWALAFPVIGATIMLPLFIWYR
HHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EDMAFGFPRFLERVNLRGGRLPLRLMFTRGISSALTIGSGGSAGQEGPIAQIGGTAGSVV
HHHHCCCHHHHHHHCCCCCCCCEEEHHHHCCCHHEEECCCCCCCCCCCCHHCCCCHHHHH
GHLLGMPEERLKVLIGCGVSGGVAATFNAPLAGVFFAHEIVLLSSFELSSFTSIVISSGM
HHHHCCCHHHHHEEEECCCCCCEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCH
ATVVSRAMYGDIPAFDVPAYQLVHPLELVLYALLGIVCGCVAALFITGYGKTREFFEQLR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
VNPLWKPLLGGFLAGCVGVLLPQVQGNGYGFIEKAVGNDVGWLLVTLLIVGKMAATCVTI
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GSGLPGGTFAPSLFIGSVTGMSFGFLANLLFPLHTATPGAYALVGMGAFLASVTHAPMTG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHH
IFLLFEMTGSYKVIIPIMLACSIGTAVARHFRKDGIDTADLAARGIDLRTGREETILEKI
HEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHH
QVRGVMMHDAEVLPESMTIREFLERAHTPRQHTFPLVDAGGGLAGVVTIHDFLGVAFEPD
HHHHEEEECHHHCCCHHHHHHHHHHHCCCCCCCCCEEECCCCEEHHHHHHHHHCCCCCCC
ILDKVPLGEMATDDVITVQGDESLAAALRKMDLTPIEELPVVDSGNGKVIGILSRREVIA
HHCCCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCHHHCCCEECCCCCEEEEECHHHHHH
AYNRAIVERTFRA
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]