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The map label for this gene is mtnN [H]

Identifier: 78224571

GI number: 78224571

Start: 3794963

End: 3795694

Strand: Reverse

Name: mtnN [H]

Synonym: Gmet_3381

Alternate gene names: 78224571

Gene position: 3795694-3794963 (Counterclockwise)

Preceding gene: 78224572

Following gene: 78224570

Centisome position: 94.95

GC content: 64.34

Gene sequence:

>732_bases
ATGGATTCCATTATCATTGCCGCGGCAACCAGTCTGGAGCTTTCCCTCCTCGTCCGGAGCATCGGTGCCCGGGAGGTCAG
GAGAAAAAAAGGTTTTAGCGATACCTACCGGGGGAAGGTCGGCGGCACCACGGTGCTTCTGGCCGTGACGGGGATCGGCA
AGGCGAATACCGCATCGGCGCTCACCGCGCTTCTGGAGCGGTACACTCCACGGCTCCTCATCGATACCGGCTGTGCCGGA
GCCTACGGGGGGGGCGGCCTGGCGGTGGGAGACCTGGCCGTGGCCTCGACTGAGGTCTATGGCGACGAGGGGATCCTGAC
GCCGTCCGGTTGGGAATCCCTTGAGATCATCGGCATTCCGCAGCTGGAACGGGGAGGACGCCGTTTTTTCAACGAGTTCC
CCCTGGCTCTTTTGCCGGCGGAGCGGGCCGTGCAGCTTGGCGCCGCGCTGGGGGTGCCGGTGCGGCGCGGAAGGTTTGTC
ACCGTATCCACCTGTAGTGGCACCACCGCCCGGGGGAACGCGCTGGCCCGCCGCTTCAACGCCATCTGCGAGAACATGGA
AGGAGCCGTGGCGGCCCACCTGGCGCTCAGGTACGGGATCGACTGCCTGGAGCTCCGTGGCATCAGCAACATGGTGGAAG
ACCGGGATCTCTCCGGCTGGAACATTCCCCTGGCGGTGGAGAGGGCCCAACGCTTCATACTCAAATTCCTGGAAACCTGC
AATGACGACTGA

Upstream 100 bases:

>100_bases
CATGGCGGAAAGATCGACGTGGTGAGTGAGGTGGGGAAGGGGAGCGTCTTTACGGTGTATCTCCCCCTTCAGGGTACGGT
CTGACGGAGCGCACTCCCCC

Downstream 100 bases:

>100_bases
CACCGTTCCCCTTACCCTCGGTTTTTCACCCTGCCCCAACGACACCTACATCTTTCACGCCCTGGTCCACGGCCTGGTCG
ACACGGGGGGGCTCACCTTC

Product: purine phosphorylase family protein 1

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MDSIIIAAATSLELSLLVRSIGAREVRRKKGFSDTYRGKVGGTTVLLAVTGIGKANTASALTALLERYTPRLLIDTGCAG
AYGGGGLAVGDLAVASTEVYGDEGILTPSGWESLEIIGIPQLERGGRRFFNEFPLALLPAERAVQLGAALGVPVRRGRFV
TVSTCSGTTARGNALARRFNAICENMEGAVAAHLALRYGIDCLELRGISNMVEDRDLSGWNIPLAVERAQRFILKFLETC
NDD

Sequences:

>Translated_243_residues
MDSIIIAAATSLELSLLVRSIGAREVRRKKGFSDTYRGKVGGTTVLLAVTGIGKANTASALTALLERYTPRLLIDTGCAG
AYGGGGLAVGDLAVASTEVYGDEGILTPSGWESLEIIGIPQLERGGRRFFNEFPLALLPAERAVQLGAALGVPVRRGRFV
TVSTCSGTTARGNALARRFNAICENMEGAVAAHLALRYGIDCLELRGISNMVEDRDLSGWNIPLAVERAQRFILKFLETC
NDD
>Mature_243_residues
MDSIIIAAATSLELSLLVRSIGAREVRRKKGFSDTYRGKVGGTTVLLAVTGIGKANTASALTALLERYTPRLLIDTGCAG
AYGGGGLAVGDLAVASTEVYGDEGILTPSGWESLEIIGIPQLERGGRRFFNEFPLALLPAERAVQLGAALGVPVRRGRFV
TVSTCSGTTARGNALARRFNAICENMEGAVAAHLALRYGIDCLELRGISNMVEDRDLSGWNIPLAVERAQRFILKFLETC
NDD

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 25845; Mature: 25845

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSIIIAAATSLELSLLVRSIGAREVRRKKGFSDTYRGKVGGTTVLLAVTGIGKANTASA
CCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEEEECCCCCCHHHH
LTALLERYTPRLLIDTGCAGAYGGGGLAVGDLAVASTEVYGDEGILTPSGWESLEIIGIP
HHHHHHHCCCEEEEECCCCCCCCCCCEEEHHHHHHHHEEECCCCCCCCCCCCCEEEEECC
QLERGGRRFFNEFPLALLPAERAVQLGAALGVPVRRGRFVTVSTCSGTTARGNALARRFN
CHHHHHHHHHHHCCEEEECHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHH
AICENMEGAVAAHLALRYGIDCLELRGISNMVEDRDLSGWNIPLAVERAQRFILKFLETC
HHHHCCCHHHHHHHHHHHCCCCEECCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
NDD
CCC
>Mature Secondary Structure
MDSIIIAAATSLELSLLVRSIGAREVRRKKGFSDTYRGKVGGTTVLLAVTGIGKANTASA
CCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEEEECCCCCCHHHH
LTALLERYTPRLLIDTGCAGAYGGGGLAVGDLAVASTEVYGDEGILTPSGWESLEIIGIP
HHHHHHHCCCEEEEECCCCCCCCCCCEEEHHHHHHHHEEECCCCCCCCCCCCCEEEEECC
QLERGGRRFFNEFPLALLPAERAVQLGAALGVPVRRGRFVTVSTCSGTTARGNALARRFN
CHHHHHHHHHHHCCEEEECHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHH
AICENMEGAVAAHLALRYGIDCLELRGISNMVEDRDLSGWNIPLAVERAQRFILKFLETC
HHHHCCCHHHHHHHHHHHCCCCEECCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
NDD
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]