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The map label for this gene is nuoG2 [H]

Identifier: 78224539

GI number: 78224539

Start: 3765060

End: 3767546

Strand: Reverse

Name: nuoG2 [H]

Synonym: Gmet_3349

Alternate gene names: 78224539

Gene position: 3767546-3765060 (Counterclockwise)

Preceding gene: 78224540

Following gene: 78224538

Centisome position: 94.25

GC content: 49.54

Gene sequence:

>2487_bases
ATGGTAAATCTCACGATTGACGGAAAACAGGTAACGGTACCCAAGGACGCTACCATTTACGATGCTGCAAAATCAGCCGG
CATCAGGATACCCATTCTCTGTCACGACAAGAAGCTCCATCCCTTCGGCGGTTGCCGTATGTGTCTTGTCGAGGTCGAAC
AGATGAAAGGGCGCCAGATTCCGGCGTGTACGACCCCTGTAACTGAGGGCATGATAGTCAACACCATGACTCCTGAGATT
ATTCAGGCCCGTAAGCTCGTTCTTGAACTACTGTTGCTGAAGCATCCAATCGACTGTCCTGTTTGCGACGCCGCTGGCGA
TTGCGACCTCCAGAATCTCACCTACGAATACCAGGTGAATTCAAATCGGTTCAAAGATGAAAAATTTCAGCATCAGATCG
ACTACCAAAACCCGCTCATTGAACGGGACATGAATCGTTGCGTTCACTGCGGCAAGTGTGCTCGAATCTGTGATGAAATA
GTTTCATTCGGCGCCTATACCTTTATCAATCGGGGTCTTGAAGCAAAAATTGGTACAGAGTTCGATGGACCGCTTAATTG
CGAGTTTTGCGGATCATGTGTATCAGTTTGCCCCGTTGGCGCTCTCGTGAGCAGACCGTTCAAATTCAAGGCCCGCTGGT
GGTCATTGAATAAAGTGAAGACGGTTTGTTCTTACTGCGGAACGGGGTGCCAGCTAACTCTTGGGGTAAAGGATAACAAA
GTACTTACCACGGTCTATGACGAGAATCAGGGTTTCCATAATGGTCAGCTTTGTACTCGTGGTAGATTTGGATATCAATT
CGTGAACAGTGATAAGCGTCTCAAGACACCACTGGTCAAGAAGAACGGTAAGCTTGAGGAGGCCAGCTGGGACGAAGCTC
TCGGACTGGTACACCAGAGACTTGCTGATGCAAAAAGCGTTGGTGCATCATCTGTTGCCGGACTGGTAACGCCCCGTCTT
ACCAATGAAGAGCTCTATCTTTTCAAGCAGCTTTTCAATAAAGGAATTGGGTCCGATAACATTGATCACTCGGCAGGCTA
CGCCCACGATGCGTTGACAGCGGGCGCGGTCGAGAGCCTTGGGTATCCAGCCTCGCCAGCTTCTATTTCGGATATTCAGA
CAACGAATCTGTTGTTGGTTGTGAAGACGGATGCTTACGAAACGCACCCTGTCCTTGGCTTTGAGATAAATCTCGGAGTG
AAGCGCAAAGGCGTTAATCTCCGAATTGTGTCGGACAAGAAAGGTAAGCTTTCAAAACTTCCGAACGCTATTACATATGT
TCATAAGCCCGCAAGTGAAGTCCTCCTCTTTAATGCCCTTGCAAAGGTCATCGTTGATGAGGGACTTGCTGACAGCTCAG
CCTCATCCCTCCCTGGTTATGACGATTTCGTTAAGAATCTCGGGGCATGTGCTCCGGCTATTGTCGCAGCCCAGTGTGGT
ATGTCAATTGAAGATATTACAACCCTTGCACGCGACTATGCAAAAGCCGAGAAGGCACTCATCATGCTGCCCATCGGGCT
TGCCTATCCGGGGCATGGGAAGGCGCTTGCCCAAGCCACCATCAACCTTGCGTTGCTTACGGGCAAGATTGGCAAAGAAG
GGTGTGGCGTTCTCATAATGGGCGAGAAGAACAATAGCCAGGGGGCTGCTGATCTTAGGATTCATCCGGTTGCAGGTGGT
CGTGATGCCATGGGAATTCTAGACGGTTGTGCTTCAGGCGCCATCAAGACACTGTACGTAGTTGGTGAGAATCCCGTTAT
CTCTTACCCGAACCGTAAAAAGGTCGAAGCTGCTCTCGATGCTGTCGAGTTCCTTGTGGTTCAGGATCTGTTTATGACCG
AGACGGCCAGTAAAGCAGATGTCGTTCTCCCGGCATGCTCCTTTGCTGAGAAGAATGGTACCTTTACCAGCGCCGGTAAG
GCCGTTCAAAGGGTTCGCAAAGCAATAGATACTATCGGCATGGCCCGCAGTGACTTTGATATATTTAACTCTTTGTATTC
AACCCTTGGGTGTGACTCCTTTAAAGGATTGTCGGAAGTTTTTGCCGAGATTGCGTCTGTGGTTCCTTCGTACAGTGGGC
TTACTTTCGATGGTTTGGACGAGAACGGTTCAGTCTATTCAGTTGCCAACAGGCTGCGGTTCGTTTCAACGGTTGCGGAT
GGCCAGGAGTCGGCAGCTGGTGCGATGGCTCTCGTTACGGGCAATGCTCTCAATCATTGCGGTACCTTGTCGCTGCATGG
GGAAGGCCCCATGTATGTCTGCCCAGAAGGATATGTAGAGTTGAATAGTGGCGATGCTAAAAAACTTGGCGTTGAAAATG
ACCAGACGTTAACAGTGAAATCGTCTGTTGGAGAAGTCAAGCTGAAGGCCAAAGTAAGTATGCGCATGCCTGAAGGTGTT
GTGTTCGCGCCGTATCATTTTTCCGACATGTCCATTAACAGTATCACCAACGGTGCACCTGTTACGTGGGTTACAATAAG
CAAGTAG

Upstream 100 bases:

>100_bases
AAAGTGTACAAAATGTAAGTCGTGTTATGACGCCTGTCGGTTCATGGCGATTGAGTAACAGCTCGATGAGCTAACTATCC
GAGGTTATACAGAGGTCAAG

Downstream 100 bases:

>100_bases
CTATACTTGGATGTAAAGTCCACTCACAACACCATCACATCAAGAGGGGAAGAGTGCAAATGGGATACGAAATATTGGGA
TTGCCGATGGCATACTACAT

Product: NADH dehydrogenase I subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G 2; NDH-1 subunit G 2 [H]

Number of amino acids: Translated: 828; Mature: 828

Protein sequence:

>828_residues
MVNLTIDGKQVTVPKDATIYDAAKSAGIRIPILCHDKKLHPFGGCRMCLVEVEQMKGRQIPACTTPVTEGMIVNTMTPEI
IQARKLVLELLLLKHPIDCPVCDAAGDCDLQNLTYEYQVNSNRFKDEKFQHQIDYQNPLIERDMNRCVHCGKCARICDEI
VSFGAYTFINRGLEAKIGTEFDGPLNCEFCGSCVSVCPVGALVSRPFKFKARWWSLNKVKTVCSYCGTGCQLTLGVKDNK
VLTTVYDENQGFHNGQLCTRGRFGYQFVNSDKRLKTPLVKKNGKLEEASWDEALGLVHQRLADAKSVGASSVAGLVTPRL
TNEELYLFKQLFNKGIGSDNIDHSAGYAHDALTAGAVESLGYPASPASISDIQTTNLLLVVKTDAYETHPVLGFEINLGV
KRKGVNLRIVSDKKGKLSKLPNAITYVHKPASEVLLFNALAKVIVDEGLADSSASSLPGYDDFVKNLGACAPAIVAAQCG
MSIEDITTLARDYAKAEKALIMLPIGLAYPGHGKALAQATINLALLTGKIGKEGCGVLIMGEKNNSQGAADLRIHPVAGG
RDAMGILDGCASGAIKTLYVVGENPVISYPNRKKVEAALDAVEFLVVQDLFMTETASKADVVLPACSFAEKNGTFTSAGK
AVQRVRKAIDTIGMARSDFDIFNSLYSTLGCDSFKGLSEVFAEIASVVPSYSGLTFDGLDENGSVYSVANRLRFVSTVAD
GQESAAGAMALVTGNALNHCGTLSLHGEGPMYVCPEGYVELNSGDAKKLGVENDQTLTVKSSVGEVKLKAKVSMRMPEGV
VFAPYHFSDMSINSITNGAPVTWVTISK

Sequences:

>Translated_828_residues
MVNLTIDGKQVTVPKDATIYDAAKSAGIRIPILCHDKKLHPFGGCRMCLVEVEQMKGRQIPACTTPVTEGMIVNTMTPEI
IQARKLVLELLLLKHPIDCPVCDAAGDCDLQNLTYEYQVNSNRFKDEKFQHQIDYQNPLIERDMNRCVHCGKCARICDEI
VSFGAYTFINRGLEAKIGTEFDGPLNCEFCGSCVSVCPVGALVSRPFKFKARWWSLNKVKTVCSYCGTGCQLTLGVKDNK
VLTTVYDENQGFHNGQLCTRGRFGYQFVNSDKRLKTPLVKKNGKLEEASWDEALGLVHQRLADAKSVGASSVAGLVTPRL
TNEELYLFKQLFNKGIGSDNIDHSAGYAHDALTAGAVESLGYPASPASISDIQTTNLLLVVKTDAYETHPVLGFEINLGV
KRKGVNLRIVSDKKGKLSKLPNAITYVHKPASEVLLFNALAKVIVDEGLADSSASSLPGYDDFVKNLGACAPAIVAAQCG
MSIEDITTLARDYAKAEKALIMLPIGLAYPGHGKALAQATINLALLTGKIGKEGCGVLIMGEKNNSQGAADLRIHPVAGG
RDAMGILDGCASGAIKTLYVVGENPVISYPNRKKVEAALDAVEFLVVQDLFMTETASKADVVLPACSFAEKNGTFTSAGK
AVQRVRKAIDTIGMARSDFDIFNSLYSTLGCDSFKGLSEVFAEIASVVPSYSGLTFDGLDENGSVYSVANRLRFVSTVAD
GQESAAGAMALVTGNALNHCGTLSLHGEGPMYVCPEGYVELNSGDAKKLGVENDQTLTVKSSVGEVKLKAKVSMRMPEGV
VFAPYHFSDMSINSITNGAPVTWVTISK
>Mature_828_residues
MVNLTIDGKQVTVPKDATIYDAAKSAGIRIPILCHDKKLHPFGGCRMCLVEVEQMKGRQIPACTTPVTEGMIVNTMTPEI
IQARKLVLELLLLKHPIDCPVCDAAGDCDLQNLTYEYQVNSNRFKDEKFQHQIDYQNPLIERDMNRCVHCGKCARICDEI
VSFGAYTFINRGLEAKIGTEFDGPLNCEFCGSCVSVCPVGALVSRPFKFKARWWSLNKVKTVCSYCGTGCQLTLGVKDNK
VLTTVYDENQGFHNGQLCTRGRFGYQFVNSDKRLKTPLVKKNGKLEEASWDEALGLVHQRLADAKSVGASSVAGLVTPRL
TNEELYLFKQLFNKGIGSDNIDHSAGYAHDALTAGAVESLGYPASPASISDIQTTNLLLVVKTDAYETHPVLGFEINLGV
KRKGVNLRIVSDKKGKLSKLPNAITYVHKPASEVLLFNALAKVIVDEGLADSSASSLPGYDDFVKNLGACAPAIVAAQCG
MSIEDITTLARDYAKAEKALIMLPIGLAYPGHGKALAQATINLALLTGKIGKEGCGVLIMGEKNNSQGAADLRIHPVAGG
RDAMGILDGCASGAIKTLYVVGENPVISYPNRKKVEAALDAVEFLVVQDLFMTETASKADVVLPACSFAEKNGTFTSAGK
AVQRVRKAIDTIGMARSDFDIFNSLYSTLGCDSFKGLSEVFAEIASVVPSYSGLTFDGLDENGSVYSVANRLRFVSTVAD
GQESAAGAMALVTGNALNHCGTLSLHGEGPMYVCPEGYVELNSGDAKKLGVENDQTLTVKSSVGEVKLKAKVSMRMPEGV
VFAPYHFSDMSINSITNGAPVTWVTISK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG3383

COG function: function code R; Uncharacterized anaerobic dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=447, Percent_Identity=28.4116331096197, Blast_Score=192, Evalue=8e-49,
Organism=Escherichia coli, GI3868721, Length=677, Percent_Identity=27.917282127031, Blast_Score=263, Evalue=3e-71,
Organism=Escherichia coli, GI145693161, Length=729, Percent_Identity=24.4170096021948, Blast_Score=189, Evalue=7e-49,
Organism=Escherichia coli, GI1788534, Length=519, Percent_Identity=22.5433526011561, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI3868720, Length=219, Percent_Identity=26.027397260274, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI3868719, Length=218, Percent_Identity=25.2293577981651, Blast_Score=67, Evalue=7e-12,
Organism=Escherichia coli, GI1787778, Length=365, Percent_Identity=21.3698630136986, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1787870, Length=472, Percent_Identity=23.9406779661017, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17565758, Length=694, Percent_Identity=28.2420749279539, Blast_Score=223, Evalue=5e-58,
Organism=Caenorhabditis elegans, GI32566231, Length=648, Percent_Identity=28.7037037037037, Blast_Score=211, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI193209088, Length=247, Percent_Identity=34.412955465587, Blast_Score=162, Evalue=8e-40,
Organism=Drosophila melanogaster, GI24640559, Length=396, Percent_Identity=29.2929292929293, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24640557, Length=396, Percent_Identity=29.2929292929293, Blast_Score=194, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR000283
- InterPro:   IPR019574 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 88976; Mature: 88976

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1 ; PS00490 MOLYBDOPTERIN_PROK_2 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNLTIDGKQVTVPKDATIYDAAKSAGIRIPILCHDKKLHPFGGCRMCLVEVEQMKGRQI
CEEEEECCCEEECCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCHHHHEEEHHHHCCCCC
PACTTPVTEGMIVNTMTPEIIQARKLVLELLLLKHPIDCPVCDAAGDCDLQNLTYEYQVN
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEC
SNRFKDEKFQHQIDYQNPLIERDMNRCVHCGKCARICDEIVSFGAYTFINRGLEAKIGTE
CCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCC
FDGPLNCEFCGSCVSVCPVGALVSRPFKFKARWWSLNKVKTVCSYCGTGCQLTLGVKDNK
CCCCCCHHHHHHHHHHHCHHHHHCCCEEEEEEEECHHHHHHHHHHCCCCCEEEEECCCCE
VLTTVYDENQGFHNGQLCTRGRFGYQFVNSDKRLKTPLVKKNGKLEEASWDEALGLVHQR
EEEEEEECCCCCCCCCEEECCCCCEEEECCCCHHCCCHHHCCCCCCCCCHHHHHHHHHHH
LADAKSVGASSVAGLVTPRLTNEELYLFKQLFNKGIGSDNIDHSAGYAHDALTAGAVESL
HHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHC
GYPASPASISDIQTTNLLLVVKTDAYETHPVLGFEINLGVKRKGVNLRIVSDKKGKLSKL
CCCCCCCCCCCEEECEEEEEEEECCCCCCCEEEEEEECCEEECCCEEEEEECCCCCHHHC
PNAITYVHKPASEVLLFNALAKVIVDEGLADSSASSLPGYDDFVKNLGACAPAIVAAQCG
CCHHEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCC
MSIEDITTLARDYAKAEKALIMLPIGLAYPGHGKALAQATINLALLTGKIGKEGCGVLIM
CCHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCHHHHHHHEEEEEEECCCCCCCCCEEEE
GEKNNSQGAADLRIHPVAGGRDAMGILDGCASGAIKTLYVVGENPVISYPNRKKVEAALD
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCEEECCCCHHHHHHHH
AVEFLVVQDLFMTETASKADVVLPACSFAEKNGTFTSAGKAVQRVRKAIDTIGMARSDFD
HHHHHHHHHHHHHCCCCCCCEEEECHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHH
IFNSLYSTLGCDSFKGLSEVFAEIASVVPSYSGLTFDGLDENGSVYSVANRLRFVSTVAD
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHC
GQESAAGAMALVTGNALNHCGTLSLHGEGPMYVCPEGYVELNSGDAKKLGVENDQTLTVK
CCCCCCCEEEEEECCCCCCCEEEEECCCCCEEECCCCCEEECCCCCCCCCCCCCCEEEEE
SSVGEVKLKAKVSMRMPEGVVFAPYHFSDMSINSITNGAPVTWVTISK
CCCCCEEEEEEEEEECCCCEEECCEECCCCEECCCCCCCCEEEEEECC
>Mature Secondary Structure
MVNLTIDGKQVTVPKDATIYDAAKSAGIRIPILCHDKKLHPFGGCRMCLVEVEQMKGRQI
CEEEEECCCEEECCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCHHHHEEEHHHHCCCCC
PACTTPVTEGMIVNTMTPEIIQARKLVLELLLLKHPIDCPVCDAAGDCDLQNLTYEYQVN
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEC
SNRFKDEKFQHQIDYQNPLIERDMNRCVHCGKCARICDEIVSFGAYTFINRGLEAKIGTE
CCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCC
FDGPLNCEFCGSCVSVCPVGALVSRPFKFKARWWSLNKVKTVCSYCGTGCQLTLGVKDNK
CCCCCCHHHHHHHHHHHCHHHHHCCCEEEEEEEECHHHHHHHHHHCCCCCEEEEECCCCE
VLTTVYDENQGFHNGQLCTRGRFGYQFVNSDKRLKTPLVKKNGKLEEASWDEALGLVHQR
EEEEEEECCCCCCCCCEEECCCCCEEEECCCCHHCCCHHHCCCCCCCCCHHHHHHHHHHH
LADAKSVGASSVAGLVTPRLTNEELYLFKQLFNKGIGSDNIDHSAGYAHDALTAGAVESL
HHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHC
GYPASPASISDIQTTNLLLVVKTDAYETHPVLGFEINLGVKRKGVNLRIVSDKKGKLSKL
CCCCCCCCCCCEEECEEEEEEEECCCCCCCEEEEEEECCEEECCCEEEEEECCCCCHHHC
PNAITYVHKPASEVLLFNALAKVIVDEGLADSSASSLPGYDDFVKNLGACAPAIVAAQCG
CCHHEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCC
MSIEDITTLARDYAKAEKALIMLPIGLAYPGHGKALAQATINLALLTGKIGKEGCGVLIM
CCHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCHHHHHHHEEEEEEECCCCCCCCCEEEE
GEKNNSQGAADLRIHPVAGGRDAMGILDGCASGAIKTLYVVGENPVISYPNRKKVEAALD
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCEEECCCCHHHHHHHH
AVEFLVVQDLFMTETASKADVVLPACSFAEKNGTFTSAGKAVQRVRKAIDTIGMARSDFD
HHHHHHHHHHHHHCCCCCCCEEEECHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHH
IFNSLYSTLGCDSFKGLSEVFAEIASVVPSYSGLTFDGLDENGSVYSVANRLRFVSTVAD
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHC
GQESAAGAMALVTGNALNHCGTLSLHGEGPMYVCPEGYVELNSGDAKKLGVENDQTLTVK
CCCCCCCEEEEEECCCCCCCEEEEECCCCCEEECCCCCEEECCCCCCCCCCCCCCEEEEE
SSVGEVKLKAKVSMRMPEGVVFAPYHFSDMSINSITNGAPVTWVTISK
CCCCCEEEEEEEEEECCCCEEECCEECCCCEECCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]