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The map label for this gene is nuoI1 [H]

Identifier: 78224537

GI number: 78224537

Start: 3763537

End: 3763932

Strand: Reverse

Name: nuoI1 [H]

Synonym: Gmet_3347

Alternate gene names: 78224537

Gene position: 3763932-3763537 (Counterclockwise)

Preceding gene: 78224538

Following gene: 78224536

Centisome position: 94.16

GC content: 45.71

Gene sequence:

>396_bases
ATGATAATGCCATTGATTAATGGTCTCAAGATCACCCTGAAGCATATGTTCATGAAGCCAGTTACGCTTCAGTACCCAGA
TGAGCGGCCGACACCGTCACCCAATTTCCGTGGCTTGCATGCTCTGAAGGTTTCTCACAGTAAAGCCAAGTGTGTTTGCT
GCTATCTCTGTCCTACAGTGTGCCCAGCAAAATGCATAACCGTTGAGGCTGGTGAGGATCAGGAACACAATAAATATGCC
GAGCGGTATGAGATTGATATGCTGCGGTGCATTTTCTGCGGCTATTGTGTTGAGGCTTGCCCTGTCGATGCCCTTAAGAT
GACGGGTGAATTTGAATTGGCAAATTATAAGCGCGAAGATTTTGTATTCGTCAAAGAGCGACTCTTAGAAAAGTAA

Upstream 100 bases:

>100_bases
TCTCGGATGGAAGGTGTTCCTGCCTTTGACTCTGATCAATATCGTAGTAACTGGAATTATTGTATCACTCTAGTCACAAC
CTATTACGAGGTTACACGCC

Downstream 100 bases:

>100_bases
TAAAGGAGCAGCAATGGAAACGTTCTTCTTCATGATCGTGGCAGCAGTAGCTGTCCTGGCCAGTATTCTGGTCATTACCT
GCAAGAACCCGATCAACAGC

Product: NADH-quinone oxidoreductase, chain I

Products: NA

Alternate protein names: NADH dehydrogenase I subunit I 1; NDH-1 subunit I 1 [H]

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MIMPLINGLKITLKHMFMKPVTLQYPDERPTPSPNFRGLHALKVSHSKAKCVCCYLCPTVCPAKCITVEAGEDQEHNKYA
ERYEIDMLRCIFCGYCVEACPVDALKMTGEFELANYKREDFVFVKERLLEK

Sequences:

>Translated_131_residues
MIMPLINGLKITLKHMFMKPVTLQYPDERPTPSPNFRGLHALKVSHSKAKCVCCYLCPTVCPAKCITVEAGEDQEHNKYA
ERYEIDMLRCIFCGYCVEACPVDALKMTGEFELANYKREDFVFVKERLLEK
>Mature_131_residues
MIMPLINGLKITLKHMFMKPVTLQYPDERPTPSPNFRGLHALKVSHSKAKCVCCYLCPTVCPAKCITVEAGEDQEHNKYA
ERYEIDMLRCIFCGYCVEACPVDALKMTGEFELANYKREDFVFVKERLLEK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI4505371, Length=126, Percent_Identity=43.6507936507937, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788617, Length=116, Percent_Identity=41.3793103448276, Blast_Score=98, Evalue=2e-22,
Organism=Escherichia coli, GI1789075, Length=102, Percent_Identity=38.2352941176471, Blast_Score=69, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17555194, Length=126, Percent_Identity=42.0634920634921, Blast_Score=113, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17864306, Length=126, Percent_Identity=44.4444444444444, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR010226 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 15085; Mature: 15085

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
12.2 %Cys+Met (Translated Protein)
7.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
12.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMPLINGLKITLKHMFMKPVTLQYPDERPTPSPNFRGLHALKVSHSKAKCVCCYLCPTV
CCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCC
CPAKCITVEAGEDQEHNKYAERYEIDMLRCIFCGYCVEACPVDALKMTGEFELANYKRED
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEECCCCCHH
FVFVKERLLEK
HHHHHHHHHCC
>Mature Secondary Structure
MIMPLINGLKITLKHMFMKPVTLQYPDERPTPSPNFRGLHALKVSHSKAKCVCCYLCPTV
CCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCC
CPAKCITVEAGEDQEHNKYAERYEIDMLRCIFCGYCVEACPVDALKMTGEFELANYKRED
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEECCCCCHH
FVFVKERLLEK
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA