Click here to switch to the map view.

The map label for this gene is hupC [H]

Identifier: 78224521

GI number: 78224521

Start: 3743786

End: 3744454

Strand: Reverse

Name: hupC [H]

Synonym: Gmet_3330

Alternate gene names: 78224521

Gene position: 3744454-3743786 (Counterclockwise)

Preceding gene: 78224522

Following gene: 78224520

Centisome position: 93.67

GC content: 63.08

Gene sequence:

>669_bases
ATGGCACGGAACCGGAGCTGTCTTTACGAAAAGTACGTCTGGGAGGTCCCGGTGCGGCTGACCCACTGGGTCAACGTGAT
CGCCATCATCGTCCTCTCGGTCACCGGCTTCTACATCGGCTCCCCCAGGACCCTGGGGCTCGTTCCCGCCGACTTTGTCA
TGGGTTGGGTGCGGGTGGTGCATCTTACGGCAGGGTATGCCTTTGCCGTGAGTATCGTGAGCCGCATCTGGTGGGCCTTC
GCGGGGAACCGCTACGCCGGGTGGCGGGAGTTTGTCCCGTTCATCTATCCCGAAGGGCGGCGCGACATGGGGCGGATGTT
CCTCTACTACGTCTTCCTCTCCCGGAAGGTTCCCCACCCCACCGGCCACAACGCCCTGGCCGGAGCCACGTACCTTCTCG
TCTTTGTCCTCTATCTGGTGATGGCCGGCACCGGCTTCGCCCTCGATGCCGAGCACGCGCCAGGCGGTTTGGCGCATGTT
CTCCTCACGCCGCTCTACGCTCTCTTCAGCAACCAGGGGATGCGGCTCACCCACCACATGGGCATGTGGCTTCTCATCGC
CTTTGCCATCCATCACATCTACAGCGCTTGGCTCATGGACGTGAAGGAACGGGGCGGGGTCATGTCGAGCATCTTCGGCG
GCTACAAGCCGGTGAAGCGGGGGGAGTAG

Upstream 100 bases:

>100_bases
CACCATCCACTCCTTCGATCCGTGCCTCGCCTGCGCCGTCCACGTGGTCGATCCCCGCGGCGGCGAGCTGGTGAGCGTCA
AGGTCCTGTAGGAGGTCGCC

Downstream 100 bases:

>100_bases
AATGTCGATTCTCGTGCTCGGCATCGGGAACCTGATCATGACCGACGACGGCGCCGGCGTACGGGTGGCGCAGCGGCTCA
TGGACGGGTGCCGCTTCCCC

Product: nickel-dependent hydrogenase b-type cytochrome subunit

Products: oxidized ferredoxin; H2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MARNRSCLYEKYVWEVPVRLTHWVNVIAIIVLSVTGFYIGSPRTLGLVPADFVMGWVRVVHLTAGYAFAVSIVSRIWWAF
AGNRYAGWREFVPFIYPEGRRDMGRMFLYYVFLSRKVPHPTGHNALAGATYLLVFVLYLVMAGTGFALDAEHAPGGLAHV
LLTPLYALFSNQGMRLTHHMGMWLLIAFAIHHIYSAWLMDVKERGGVMSSIFGGYKPVKRGE

Sequences:

>Translated_222_residues
MARNRSCLYEKYVWEVPVRLTHWVNVIAIIVLSVTGFYIGSPRTLGLVPADFVMGWVRVVHLTAGYAFAVSIVSRIWWAF
AGNRYAGWREFVPFIYPEGRRDMGRMFLYYVFLSRKVPHPTGHNALAGATYLLVFVLYLVMAGTGFALDAEHAPGGLAHV
LLTPLYALFSNQGMRLTHHMGMWLLIAFAIHHIYSAWLMDVKERGGVMSSIFGGYKPVKRGE
>Mature_221_residues
ARNRSCLYEKYVWEVPVRLTHWVNVIAIIVLSVTGFYIGSPRTLGLVPADFVMGWVRVVHLTAGYAFAVSIVSRIWWAFA
GNRYAGWREFVPFIYPEGRRDMGRMFLYYVFLSRKVPHPTGHNALAGATYLLVFVLYLVMAGTGFALDAEHAPGGLAHVL
LTPLYALFSNQGMRLTHHMGMWLLIAFAIHHIYSAWLMDVKERGGVMSSIFGGYKPVKRGE

Specific function: B-type cytochrome involved in electron transfer from hydrogenase to oxygen [H]

COG id: COG1969

COG function: function code C; Ni,Fe-hydrogenase I cytochrome b subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hupC/hyaC/hydC family [H]

Homologues:

Organism=Escherichia coli, GI1787208, Length=232, Percent_Identity=34.4827586206897, Blast_Score=123, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005797
- InterPro:   IPR016174
- InterPro:   IPR000516 [H]

Pfam domain/function: PF00033 Cytochrom_B_N [H]

EC number: NA

Molecular weight: Translated: 25102; Mature: 24971

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS00882 NI_HGENASE_CYTB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARNRSCLYEKYVWEVPVRLTHWVNVIAIIVLSVTGFYIGSPRTLGLVPADFVMGWVRVV
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHH
HLTAGYAFAVSIVSRIWWAFAGNRYAGWREFVPFIYPEGRRDMGRMFLYYVFLSRKVPHP
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
TGHNALAGATYLLVFVLYLVMAGTGFALDAEHAPGGLAHVLLTPLYALFSNQGMRLTHHM
CCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHH
GMWLLIAFAIHHIYSAWLMDVKERGGVMSSIFGGYKPVKRGE
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ARNRSCLYEKYVWEVPVRLTHWVNVIAIIVLSVTGFYIGSPRTLGLVPADFVMGWVRVV
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHH
HLTAGYAFAVSIVSRIWWAFAGNRYAGWREFVPFIYPEGRRDMGRMFLYYVFLSRKVPHP
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
TGHNALAGATYLLVFVLYLVMAGTGFALDAEHAPGGLAHVLLTPLYALFSNQGMRLTHHM
CCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHH
GMWLLIAFAIHHIYSAWLMDVKERGGVMSSIFGGYKPVKRGE
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Reduced ferredoxin; 2 H+ [C]

Specific reaction: Reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2 [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1597428 [H]