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The map label for this gene is etfB [H]

Identifier: 78224491

GI number: 78224491

Start: 3713109

End: 3713885

Strand: Direct

Name: etfB [H]

Synonym: Gmet_3300

Alternate gene names: 78224491

Gene position: 3713109-3713885 (Clockwise)

Preceding gene: 78224490

Following gene: 78224492

Centisome position: 92.89

GC content: 60.62

Gene sequence:

>777_bases
ATGAAGATACTGGTCTGCATCAAACAGGTACCCGACATGGAGTCCCGCTTCAGGGTAAGCAGCTCCGGAAACTGGCTCGA
AGAATCCGATCTGGCCTTCCGGCTTAACGAGTACGACGAGTACGCCGTGGAGCAGGCGGTCCAGCTCAAGGAACAGCTGG
GGGACATCCCCGAGATCACGGTCCTCTCCATTGGCCCGGACCGGGTCGGCGAGTCCATAAGGAAGGCACTGGCCATGGGA
TGCGACCGGGGAGTCCACATCCGGGACCCCGAATCGTCCCGCAAGGATCCGTGGCAGATCGCCTCCCTCATCGCCTCCTT
CGCCGGGGACAAGGAATTTGACCTCATTCTCACCGGGATGCAATCCCAGGACCGGGGCTCCGCCCAGGTGGGAATCATGG
TGTCCGAAATCCTCGGCTATCCCTGCGCCTCCACCCTGGTCGGTTTCTCCTACGACAACGGCATCATCAGCGCCAGGCGG
GAACTGGAAGGAGGAACCAAGGCAGTCGTGCGACTCCGGACGCCGGCGGTCGTCACCTGCCAGCTGGGGCTCAACGTGCC
GCGCTACCCTACCCTTCCCAATATCATGAAGGCCAAAAAAAAGGAAATTCTGTCGGTGCCGGTGGCGGATTTCTCCGTCG
TGGACGGACATGCAACAACCCTGCGACTCTATCAGCCGGCAAAGAAGGGGGGCGGGCTCGTCATCGAGGGGGAAGTGAAT
GATCTTGCCGACAGGCTCGTGGGGATACTGAAGCAGAAAACCATGGTGCTGAGGTAG

Upstream 100 bases:

>100_bases
GGCATTCTACTTCTTCTGATCAGCGGCGGCGTGCCCCTTCCGCCGGGGGGCACGCCGCAACCGCGGAACAGGCTTAACGC
TCTTCACCTAGGAGGTCAGC

Downstream 100 bases:

>100_bases
TGACAACATGCCGGCCGCGATCAACGGTTCCGCGGCCCGCCTATGAAGGAGGTTCTATGAAGGTGCTTCTGGTGGGAGAA
TACCGCGAAGGAAAGCTCCG

Product: electron transfer flavoprotein subunit beta

Products: NA

Alternate protein names: Beta-ETF; Electron transfer flavoprotein small subunit; ETFSS [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MKILVCIKQVPDMESRFRVSSSGNWLEESDLAFRLNEYDEYAVEQAVQLKEQLGDIPEITVLSIGPDRVGESIRKALAMG
CDRGVHIRDPESSRKDPWQIASLIASFAGDKEFDLILTGMQSQDRGSAQVGIMVSEILGYPCASTLVGFSYDNGIISARR
ELEGGTKAVVRLRTPAVVTCQLGLNVPRYPTLPNIMKAKKKEILSVPVADFSVVDGHATTLRLYQPAKKGGGLVIEGEVN
DLADRLVGILKQKTMVLR

Sequences:

>Translated_258_residues
MKILVCIKQVPDMESRFRVSSSGNWLEESDLAFRLNEYDEYAVEQAVQLKEQLGDIPEITVLSIGPDRVGESIRKALAMG
CDRGVHIRDPESSRKDPWQIASLIASFAGDKEFDLILTGMQSQDRGSAQVGIMVSEILGYPCASTLVGFSYDNGIISARR
ELEGGTKAVVRLRTPAVVTCQLGLNVPRYPTLPNIMKAKKKEILSVPVADFSVVDGHATTLRLYQPAKKGGGLVIEGEVN
DLADRLVGILKQKTMVLR
>Mature_258_residues
MKILVCIKQVPDMESRFRVSSSGNWLEESDLAFRLNEYDEYAVEQAVQLKEQLGDIPEITVLSIGPDRVGESIRKALAMG
CDRGVHIRDPESSRKDPWQIASLIASFAGDKEFDLILTGMQSQDRGSAQVGIMVSEILGYPCASTLVGFSYDNGIISARR
ELEGGTKAVVRLRTPAVVTCQLGLNVPRYPTLPNIMKAKKKEILSVPVADFSVVDGHATTLRLYQPAKKGGGLVIEGEVN
DLADRLVGILKQKTMVLR

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2086

COG function: function code C; Electron transfer flavoprotein, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF beta-subunit/fixA family [H]

Homologues:

Organism=Homo sapiens, GI4503609, Length=249, Percent_Identity=35.7429718875502, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI62420877, Length=215, Percent_Identity=38.1395348837209, Blast_Score=135, Evalue=5e-32,
Organism=Escherichia coli, GI87081682, Length=220, Percent_Identity=33.1818181818182, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI87082158, Length=245, Percent_Identity=26.9387755102041, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367123, Length=208, Percent_Identity=29.8076923076923, Blast_Score=73, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25141345, Length=263, Percent_Identity=32.6996197718631, Blast_Score=130, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6321646, Length=251, Percent_Identity=31.0756972111554, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24651147, Length=215, Percent_Identity=36.2790697674419, Blast_Score=127, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24651145, Length=215, Percent_Identity=36.2790697674419, Blast_Score=127, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000049
- InterPro:   IPR014730
- InterPro:   IPR012255
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF [H]

EC number: NA

Molecular weight: Translated: 28290; Mature: 28290

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVCIKQVPDMESRFRVSSSGNWLEESDLAFRLNEYDEYAVEQAVQLKEQLGDIPEIT
CEEEEEECCCCCHHHHEEECCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCEE
VLSIGPDRVGESIRKALAMGCDRGVHIRDPESSRKDPWQIASLIASFAGDKEFDLILTGM
EEECCHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECC
QSQDRGSAQVGIMVSEILGYPCASTLVGFSYDNGIISARRELEGGTKAVVRLRTPAVVTC
CCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHCCCCCEEEEEEECCEEEEE
QLGLNVPRYPTLPNIMKAKKKEILSVPVADFSVVDGHATTLRLYQPAKKGGGLVIEGEVN
EECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCCCCEEEECCHH
DLADRLVGILKQKTMVLR
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKILVCIKQVPDMESRFRVSSSGNWLEESDLAFRLNEYDEYAVEQAVQLKEQLGDIPEIT
CEEEEEECCCCCHHHHEEECCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCEE
VLSIGPDRVGESIRKALAMGCDRGVHIRDPESSRKDPWQIASLIASFAGDKEFDLILTGM
EEECCHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECC
QSQDRGSAQVGIMVSEILGYPCASTLVGFSYDNGIISARRELEGGTKAVVRLRTPAVVTC
CCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHCCCCCEEEEEEECCEEEEE
QLGLNVPRYPTLPNIMKAKKKEILSVPVADFSVVDGHATTLRLYQPAKKGGGLVIEGEVN
EECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCCCCEEEECCHH
DLADRLVGILKQKTMVLR
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8599534; 12597275 [H]