Click here to switch to the map view.

The map label for this gene is cat2 [H]

Identifier: 78224485

GI number: 78224485

Start: 3707551

End: 3708864

Strand: Direct

Name: cat2 [H]

Synonym: Gmet_3294

Alternate gene names: 78224485

Gene position: 3707551-3708864 (Clockwise)

Preceding gene: 78224484

Following gene: 78224486

Centisome position: 92.75

GC content: 60.81

Gene sequence:

>1314_bases
ATGAATAATGCAGCATTGGCCGTATCCCGATACGAACAGGAATATCAGCAGAAGCTCTCCACCGCCGAAGAGGTGGCGGC
CACCGTCAAATCGGGGGACCATCTCTGCTTCCCCATCTGCGCCGGAGAGCCGACTCTCTTCGTCAAGGCCCTTGCAGCCC
GCAAACATGAGCTCGAAAGGGTGGTGGTAAACCAGCAGCACCACCTCTGCCCCGACTACCTCACCGAGGAGTCCACTCCC
CATATCCGGGTCAACTCCTGGTTCACGAGCCACGTCTCCCGCAAGGCGGTCCAGAACGGCTGGGCCGACTTCGTCCCCAA
CTACTTCCACGAGGTGCCCAAGCTCCTGCGGGAATACTGGCCCGTTGATATCGCGGGAACCGTGGTTTCCCCCATGGACG
AGCACGGCTTCTTCACCTGCAGCCTCTCGGTGGCCTACACCATGGAGGCGGTCAAGAAGGCGAACCGGGTGGTGGTGCAG
GTGAACCCCAATGCCCCCCGCACCCACGGCAACTGCCACATCCACATATCCGACGTGGACTTCATCATCGAAACCAACGA
CCCCATCGTCGAACTGGCCATTCCTCCCATCACCCCCATCGAGGAGGCGATTGGCGGCTACATCGCCGAACTCATCGAGG
ACGGCTCCACCCTGCAGCTCGGCATCGGCGGCATTCCCAACGCAGTCTGCAAGGCGCTCCTGAAAAAGCGAGATCTGGGA
ATTCACACCGAGATGATCACCGACGGCATGGTGGACCTCATGTTCAGCGGAGCGGTGAACAACTCTAAAAAGAACCTCCT
GCCGGGGAAGACCCTCGGCACCTTCGCCCTGGGAACCAAGCGGCTTTACGAGTTCATGAACGAGAACCCCATGATTGAGA
TGCACCCCGTGGACTTCACCAACAACCCCTACAACATCGGCCAGAACGACAAGGTGGTGGCCATCAACGCCACTATTGAG
GTGGACCTCCTGGGACAGTGCTGCTCCGAATCCCTGGGCCACGTCCAGTGGAGCGGCACCGGCGGCCAAGCCGACTTCGT
CCGGGGGGCCAACATCTCTCGCGGAGGGAAAAGCTTCATCACCACCGCCGCCACCGCCAAGAACGGAACGGTGTCGAGCA
TCGTACCGACCCTCAAGCCGGGAGCGGCGGTCACCACCAACAAGAACGACGTCGATTACGTGGTGACCGAGTTCGGGGTG
GCGAAGCTTCGCGGCCAGACCGCCCGGCAGCGTGCCCTCAACCTTATCAATATCGCCCACCCCGACTTCCGTGAGGAACT
GACGGCTGAAGCCCGGCGGATGAACCGAATTTAA

Upstream 100 bases:

>100_bases
GCCCGTCGGGCTCCCGTGTGGCTCGGGCCATGGGGTGCTCTCCACACCAGATAACGACGACGGCAAACGCCTGAACTAAA
ACAATACAGGAGGATTGACC

Downstream 100 bases:

>100_bases
AGAAATGGCCCGGGACCTGGTAGGGATTCGGAAGATACGCCGAGGAATATTCCGAGTCCCAAGGCCTGGGACCGCACCGC
GCGCCGGGAGGGGCGCCTCC

Product: Acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MNNAALAVSRYEQEYQQKLSTAEEVAATVKSGDHLCFPICAGEPTLFVKALAARKHELERVVVNQQHHLCPDYLTEESTP
HIRVNSWFTSHVSRKAVQNGWADFVPNYFHEVPKLLREYWPVDIAGTVVSPMDEHGFFTCSLSVAYTMEAVKKANRVVVQ
VNPNAPRTHGNCHIHISDVDFIIETNDPIVELAIPPITPIEEAIGGYIAELIEDGSTLQLGIGGIPNAVCKALLKKRDLG
IHTEMITDGMVDLMFSGAVNNSKKNLLPGKTLGTFALGTKRLYEFMNENPMIEMHPVDFTNNPYNIGQNDKVVAINATIE
VDLLGQCCSESLGHVQWSGTGGQADFVRGANISRGGKSFITTAATAKNGTVSSIVPTLKPGAAVTTNKNDVDYVVTEFGV
AKLRGQTARQRALNLINIAHPDFREELTAEARRMNRI

Sequences:

>Translated_437_residues
MNNAALAVSRYEQEYQQKLSTAEEVAATVKSGDHLCFPICAGEPTLFVKALAARKHELERVVVNQQHHLCPDYLTEESTP
HIRVNSWFTSHVSRKAVQNGWADFVPNYFHEVPKLLREYWPVDIAGTVVSPMDEHGFFTCSLSVAYTMEAVKKANRVVVQ
VNPNAPRTHGNCHIHISDVDFIIETNDPIVELAIPPITPIEEAIGGYIAELIEDGSTLQLGIGGIPNAVCKALLKKRDLG
IHTEMITDGMVDLMFSGAVNNSKKNLLPGKTLGTFALGTKRLYEFMNENPMIEMHPVDFTNNPYNIGQNDKVVAINATIE
VDLLGQCCSESLGHVQWSGTGGQADFVRGANISRGGKSFITTAATAKNGTVSSIVPTLKPGAAVTTNKNDVDYVVTEFGV
AKLRGQTARQRALNLINIAHPDFREELTAEARRMNRI
>Mature_437_residues
MNNAALAVSRYEQEYQQKLSTAEEVAATVKSGDHLCFPICAGEPTLFVKALAARKHELERVVVNQQHHLCPDYLTEESTP
HIRVNSWFTSHVSRKAVQNGWADFVPNYFHEVPKLLREYWPVDIAGTVVSPMDEHGFFTCSLSVAYTMEAVKKANRVVVQ
VNPNAPRTHGNCHIHISDVDFIIETNDPIVELAIPPITPIEEAIGGYIAELIEDGSTLQLGIGGIPNAVCKALLKKRDLG
IHTEMITDGMVDLMFSGAVNNSKKNLLPGKTLGTFALGTKRLYEFMNENPMIEMHPVDFTNNPYNIGQNDKVVAINATIE
VDLLGQCCSESLGHVQWSGTGGQADFVRGANISRGGKSFITTAATAKNGTVSSIVPTLKPGAAVTTNKNDVDYVVTEFGV
AKLRGQTARQRALNLINIAHPDFREELTAEARRMNRI

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=472, Percent_Identity=23.9406779661017, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32563853, Length=426, Percent_Identity=39.906103286385, Blast_Score=288, Evalue=4e-78,
Organism=Caenorhabditis elegans, GI17538151, Length=424, Percent_Identity=37.2641509433962, Blast_Score=263, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6319456, Length=391, Percent_Identity=25.8312020460358, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21358615, Length=416, Percent_Identity=42.7884615384615, Blast_Score=310, Evalue=1e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 47933; Mature: 47933

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNAALAVSRYEQEYQQKLSTAEEVAATVKSGDHLCFPICAGEPTLFVKALAARKHELER
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
VVVNQQHHLCPDYLTEESTPHIRVNSWFTSHVSRKAVQNGWADFVPNYFHEVPKLLREYW
HHHCCCCCCCCHHHCCCCCCCEEEECHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHC
PVDIAGTVVSPMDEHGFFTCSLSVAYTMEAVKKANRVVVQVNPNAPRTHGNCHIHISDVD
CCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEEEECEE
FIIETNDPIVELAIPPITPIEEAIGGYIAELIEDGSTLQLGIGGIPNAVCKALLKKRDLG
EEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCC
IHTEMITDGMVDLMFSGAVNNSKKNLLPGKTLGTFALGTKRLYEFMNENPMIEMHPVDFT
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCC
NNPYNIGQNDKVVAINATIEVDLLGQCCSESLGHVQWSGTGGQADFVRGANISRGGKSFI
CCCCCCCCCCEEEEEEEEEEEEHHHHHHHHHHCCEEECCCCCCCCEEECCCCCCCCCHHE
TTAATAKNGTVSSIVPTLKPGAAVTTNKNDVDYVVTEFGVAKLRGQTARQRALNLINIAH
EEEECCCCCCHHHHCCCCCCCCEEECCCCCCCEEHHHHHHHHHCCHHHHHHHHHHHCCCC
PDFREELTAEARRMNRI
CCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNAALAVSRYEQEYQQKLSTAEEVAATVKSGDHLCFPICAGEPTLFVKALAARKHELER
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHH
VVVNQQHHLCPDYLTEESTPHIRVNSWFTSHVSRKAVQNGWADFVPNYFHEVPKLLREYW
HHHCCCCCCCCHHHCCCCCCCEEEECHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHC
PVDIAGTVVSPMDEHGFFTCSLSVAYTMEAVKKANRVVVQVNPNAPRTHGNCHIHISDVD
CCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEEEECEE
FIIETNDPIVELAIPPITPIEEAIGGYIAELIEDGSTLQLGIGGIPNAVCKALLKKRDLG
EEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCC
IHTEMITDGMVDLMFSGAVNNSKKNLLPGKTLGTFALGTKRLYEFMNENPMIEMHPVDFT
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCC
NNPYNIGQNDKVVAINATIEVDLLGQCCSESLGHVQWSGTGGQADFVRGANISRGGKSFI
CCCCCCCCCCEEEEEEEEEEEEHHHHHHHHHHCCEEECCCCCCCCEEECCCCCCCCCHHE
TTAATAKNGTVSSIVPTLKPGAAVTTNKNDVDYVVTEFGVAKLRGQTARQRALNLINIAH
EEEECCCCCCHHHHCCCCCCCCEEECCCCCCCEEHHHHHHHHHCCHHHHHHHHHHHCCCC
PDFREELTAEARRMNRI
CCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]