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The map label for this gene is ywcA [H]

Identifier: 78224479

GI number: 78224479

Start: 3698350

End: 3700317

Strand: Direct

Name: ywcA [H]

Synonym: Gmet_3288

Alternate gene names: 78224479

Gene position: 3698350-3700317 (Clockwise)

Preceding gene: 78224478

Following gene: 78224480

Centisome position: 92.52

GC content: 61.38

Gene sequence:

>1968_bases
ATGAAACGATTGGCTCCATTTTGTATTGCAGCACTTCTCATGGGGGGCGCAGCCGTCGCAGCCGAACCAGCCAAGCAAGC
GACACCCTCCCAGACCTCCGCCGTTTCCGCGGCGGCCCCGGCGCCAGCCCCTATGGCATCCGCGGCGGCCGCGACGGCCA
AGAGCACTGCCGCCCCCGCAGCCGGCGCGCCCGCCAAGATCAAGACCAACAAGGCCATCACCCTCAGCATGTTTGCCCTC
ATCGTCCTCGCCACCCTGGGGGTCGTGGTCTGGGCAGCCAGGAAGACCCAGACCGCTGCCGACTACTACACAGCCGGCGG
CGGCATCACCGGCCTGCAGAACGGTTGGGCCATCACCGGCGACGTGGTCTCGGCTGCCTCGTTCCTGGGCATGTCGGGAC
TCATCTCTCTCTACGGGATCGACGGGTTTCTCTACTCCACCGGACCGATCCTCGGCTTCGTGACCATTCTCCTCCTCATG
GCTGAACCGCTCCGCAACGCCGGTAAGTACACCATGGGTGACATCCTCTGCTTCCGGGCCTCCCCGAAGCCGGTCCGGGC
CGCGGCGGCCATCTCCACCGTGGCGGTTTCCACCTTTTATCTCCTGGCCCAGATGGTGGGCGCCGGCAAACTGATGCAGC
TCCTGTTGGACATCCCCTACAAGGTGTCGGTCATCGGCGTCGGCACACTCCTCATTATCTATGTGGTGTTCGGCGGCATG
AAGGCCACTACCTGGGTACAGATCATTAAAGCGTCTCTCCTTCTGTCCGCTGCGGTGCTTCTGTCGATATTGGTGGCGGT
CAAGGCGGGGATGAACCCCCTGCGCCTCTTTGCAGACGTGGTCAACAGCGGCGCTGTTCAGGATCATGTCAGGATCGCCG
TGCTCAAGCATCCGCTCCCCGAGCCTGGATTCGATTACGGCAGGCGCTTCCTCCAGCCAGGCCTCTTCCTGAAGAATCCC
CTCGACCAGATATCGCTGGGCCTCGCTTGGGTTCTGGGAGCCGCCGGCCTCCCTCATATCATGATGCGCTTCTTCACGGT
GCCCAACGCCAAAGAGGCGCGTAAGTCGATCCGGGTCTCGGTTTTCCTTATGGGTGCCTTTTTCATCATGACTACCTTCC
TCGGCTTCGGCGCCGCCATCCACATCACCCCCCAGAAGGTCGCAGCCATGGACAAAGGTGGCAACATGGCGACCCTCCTG
CTTGCCCAGTACCTGGGCGGGGGTGAAGGCTCCATTGGCGGCGACCTATTCCTCGCCTTCGTCTGTGCGGTGGCCTTCGC
CACCATCCTGGCCGTCGTCTCGGGGCTGGTGCTTGCGGCCTCCGCCGCCATTGCCCACGACATCTACGTAAACATCGTAA
AAAACGGCAAGGCCGACCAGAAGGAACAGGTCCTGACCGCCCGCATCACTTCGCTTGTGGTGGGCACGGCCGCCATCTGG
CTGGGAATCGCCGCCGAAAAGGAGAATATCGTCGCCCTGGTGGCCCTTGCCTTTGCCGTGGCCGCATCGGGTAACTTCCC
GGTCATCATCCTCTCGCTCTTCTGGCGCAAGTTCAACACAGCGGGGATCGTCTCGGGCATTGTGGTCGGCACCATTGCCG
CAATTGGCCTCGTGCTGGTCTCTCCCAACATGACCTACCCGAAAAAAATCGCAGCCGATGCCAAGAATGTGATTGATACC
CTGGAGAAAAAGCAGGCGACCGGCGAGATCCTGGCGGAGAAGGATCTGAACGCCCTGAACAAGGCACGAACCGACTACAC
CAAGAACAAGGACGGCAAGTCGATCATGGGGCTGGACAATCCGCTCTTCCCGCTGAAGAACCCCGGCATCGTCTCTGTCC
CCCTCGGCTTCCTGGCCGCCATCATCGGCTGCCTGGCCTTCAGGGATCGCCGTGCCGAAGAGATGTTCGACGAAATCTAT
GTACGTCAAAATACCGGAATTGGTATTGCCGAGGCAATAGATCACTAA

Upstream 100 bases:

>100_bases
CGTAAGCTTCGGCATTGCCATTCACTACGGCAGGGTTGCCGACAGGGACTTCGACAGGCTCACCCAGGAGCTTGTCAAGC
AAATCGGATAGGAGGGTATG

Downstream 100 bases:

>100_bases
TTATGTACCAAAATATTTATAATATGTCATAGCCATAACATTCAATTCACATCACACACAAGAGCACACGGATAATTATC
TGTGTGCTCTTCTTTTTGTC

Product: Na+/solute symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 655; Mature: 655

Protein sequence:

>655_residues
MKRLAPFCIAALLMGGAAVAAEPAKQATPSQTSAVSAAAPAPAPMASAAAATAKSTAAPAAGAPAKIKTNKAITLSMFAL
IVLATLGVVVWAARKTQTAADYYTAGGGITGLQNGWAITGDVVSAASFLGMSGLISLYGIDGFLYSTGPILGFVTILLLM
AEPLRNAGKYTMGDILCFRASPKPVRAAAAISTVAVSTFYLLAQMVGAGKLMQLLLDIPYKVSVIGVGTLLIIYVVFGGM
KATTWVQIIKASLLLSAAVLLSILVAVKAGMNPLRLFADVVNSGAVQDHVRIAVLKHPLPEPGFDYGRRFLQPGLFLKNP
LDQISLGLAWVLGAAGLPHIMMRFFTVPNAKEARKSIRVSVFLMGAFFIMTTFLGFGAAIHITPQKVAAMDKGGNMATLL
LAQYLGGGEGSIGGDLFLAFVCAVAFATILAVVSGLVLAASAAIAHDIYVNIVKNGKADQKEQVLTARITSLVVGTAAIW
LGIAAEKENIVALVALAFAVAASGNFPVIILSLFWRKFNTAGIVSGIVVGTIAAIGLVLVSPNMTYPKKIAADAKNVIDT
LEKKQATGEILAEKDLNALNKARTDYTKNKDGKSIMGLDNPLFPLKNPGIVSVPLGFLAAIIGCLAFRDRRAEEMFDEIY
VRQNTGIGIAEAIDH

Sequences:

>Translated_655_residues
MKRLAPFCIAALLMGGAAVAAEPAKQATPSQTSAVSAAAPAPAPMASAAAATAKSTAAPAAGAPAKIKTNKAITLSMFAL
IVLATLGVVVWAARKTQTAADYYTAGGGITGLQNGWAITGDVVSAASFLGMSGLISLYGIDGFLYSTGPILGFVTILLLM
AEPLRNAGKYTMGDILCFRASPKPVRAAAAISTVAVSTFYLLAQMVGAGKLMQLLLDIPYKVSVIGVGTLLIIYVVFGGM
KATTWVQIIKASLLLSAAVLLSILVAVKAGMNPLRLFADVVNSGAVQDHVRIAVLKHPLPEPGFDYGRRFLQPGLFLKNP
LDQISLGLAWVLGAAGLPHIMMRFFTVPNAKEARKSIRVSVFLMGAFFIMTTFLGFGAAIHITPQKVAAMDKGGNMATLL
LAQYLGGGEGSIGGDLFLAFVCAVAFATILAVVSGLVLAASAAIAHDIYVNIVKNGKADQKEQVLTARITSLVVGTAAIW
LGIAAEKENIVALVALAFAVAASGNFPVIILSLFWRKFNTAGIVSGIVVGTIAAIGLVLVSPNMTYPKKIAADAKNVIDT
LEKKQATGEILAEKDLNALNKARTDYTKNKDGKSIMGLDNPLFPLKNPGIVSVPLGFLAAIIGCLAFRDRRAEEMFDEIY
VRQNTGIGIAEAIDH
>Mature_655_residues
MKRLAPFCIAALLMGGAAVAAEPAKQATPSQTSAVSAAAPAPAPMASAAAATAKSTAAPAAGAPAKIKTNKAITLSMFAL
IVLATLGVVVWAARKTQTAADYYTAGGGITGLQNGWAITGDVVSAASFLGMSGLISLYGIDGFLYSTGPILGFVTILLLM
AEPLRNAGKYTMGDILCFRASPKPVRAAAAISTVAVSTFYLLAQMVGAGKLMQLLLDIPYKVSVIGVGTLLIIYVVFGGM
KATTWVQIIKASLLLSAAVLLSILVAVKAGMNPLRLFADVVNSGAVQDHVRIAVLKHPLPEPGFDYGRRFLQPGLFLKNP
LDQISLGLAWVLGAAGLPHIMMRFFTVPNAKEARKSIRVSVFLMGAFFIMTTFLGFGAAIHITPQKVAAMDKGGNMATLL
LAQYLGGGEGSIGGDLFLAFVCAVAFATILAVVSGLVLAASAAIAHDIYVNIVKNGKADQKEQVLTARITSLVVGTAAIW
LGIAAEKENIVALVALAFAVAASGNFPVIILSLFWRKFNTAGIVSGIVVGTIAAIGLVLVSPNMTYPKKIAADAKNVIDT
LEKKQATGEILAEKDLNALNKARTDYTKNKDGKSIMGLDNPLFPLKNPGIVSVPLGFLAAIIGCLAFRDRRAEEMFDEIY
VRQNTGIGIAEAIDH

Specific function: Unknown

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=352, Percent_Identity=24.4318181818182, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1790503, Length=623, Percent_Identity=39.3258426966292, Blast_Score=398, Evalue=1e-112,
Organism=Escherichia coli, GI1787251, Length=463, Percent_Identity=25.0539956803456, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI87082237, Length=479, Percent_Identity=23.3820459290188, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 68275; Mature: 68275

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLAPFCIAALLMGGAAVAAEPAKQATPSQTSAVSAAAPAPAPMASAAAATAKSTAAPA
CCCCHHHHHHHHHHCCHHHHCCCHHCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCC
AGAPAKIKTNKAITLSMFALIVLATLGVVVWAARKTQTAADYYTAGGGITGLQNGWAITG
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCCCCEEEH
DVVSAASFLGMSGLISLYGIDGFLYSTGPILGFVTILLLMAEPLRNAGKYTMGDILCFRA
HHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHEEEECC
SPKPVRAAAAISTVAVSTFYLLAQMVGAGKLMQLLLDIPYKVSVIGVGTLLIIYVVFGGM
CCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCC
KATTWVQIIKASLLLSAAVLLSILVAVKAGMNPLRLFADVVNSGAVQDHVRIAVLKHPLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHEEEEEECCCC
EPGFDYGRRFLQPGLFLKNPLDQISLGLAWVLGAAGLPHIMMRFFTVPNAKEARKSIRVS
CCCHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHH
VFLMGAFFIMTTFLGFGAAIHITPQKVAAMDKGGNMATLLLAQYLGGGEGSIGGDLFLAF
HHHHHHHHHHHHHHHCCCEEEECHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
VCAVAFATILAVVSGLVLAASAAIAHDIYVNIVKNGKADQKEQVLTARITSLVVGTAAIW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
LGIAAEKENIVALVALAFAVAASGNFPVIILSLFWRKFNTAGIVSGIVVGTIAAIGLVLV
HHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEE
SPNMTYPKKIAADAKNVIDTLEKKQATGEILAEKDLNALNKARTDYTKNKDGKSIMGLDN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCC
PLFPLKNPGIVSVPLGFLAAIIGCLAFRDRRAEEMFDEIYVRQNTGIGIAEAIDH
CCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCC
>Mature Secondary Structure
MKRLAPFCIAALLMGGAAVAAEPAKQATPSQTSAVSAAAPAPAPMASAAAATAKSTAAPA
CCCCHHHHHHHHHHCCHHHHCCCHHCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCC
AGAPAKIKTNKAITLSMFALIVLATLGVVVWAARKTQTAADYYTAGGGITGLQNGWAITG
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCCCCCCEEEH
DVVSAASFLGMSGLISLYGIDGFLYSTGPILGFVTILLLMAEPLRNAGKYTMGDILCFRA
HHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHEEEECC
SPKPVRAAAAISTVAVSTFYLLAQMVGAGKLMQLLLDIPYKVSVIGVGTLLIIYVVFGGM
CCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCC
KATTWVQIIKASLLLSAAVLLSILVAVKAGMNPLRLFADVVNSGAVQDHVRIAVLKHPLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHEEEEEECCCC
EPGFDYGRRFLQPGLFLKNPLDQISLGLAWVLGAAGLPHIMMRFFTVPNAKEARKSIRVS
CCCHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHH
VFLMGAFFIMTTFLGFGAAIHITPQKVAAMDKGGNMATLLLAQYLGGGEGSIGGDLFLAF
HHHHHHHHHHHHHHHCCCEEEECHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
VCAVAFATILAVVSGLVLAASAAIAHDIYVNIVKNGKADQKEQVLTARITSLVVGTAAIW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
LGIAAEKENIVALVALAFAVAASGNFPVIILSLFWRKFNTAGIVSGIVVGTIAAIGLVLV
HHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEE
SPNMTYPKKIAADAKNVIDTLEKKQATGEILAEKDLNALNKARTDYTKNKDGKSIMGLDN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCC
PLFPLKNPGIVSVPLGFLAAIIGCLAFRDRRAEEMFDEIYVRQNTGIGIAEAIDH
CCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]