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The map label for this gene is exuT [H]

Identifier: 78224412

GI number: 78224412

Start: 3621151

End: 3622401

Strand: Direct

Name: exuT [H]

Synonym: Gmet_3221

Alternate gene names: 78224412

Gene position: 3621151-3622401 (Clockwise)

Preceding gene: 78224411

Following gene: 78224413

Centisome position: 90.59

GC content: 66.35

Gene sequence:

>1251_bases
ATGCATATCAACGCTCCGTCGCCCCCCTCGAAAAGCTCTCCCTACGCACGCTACGTCCTGGCCCTCCTTCTGGGGGTCAA
CCTTCTCAACTACATCGACCGCCAGGTCCTCTATGCCGTCTTTCCCCTCATCCAGCACGATTTCAGCCTCTCCGACACCG
CCCTGGGGCTTCTGGGAAGCGGCTTCATGGTCACCTACATGGTATCGGCTCCCCTCTTCGGGTGGCTCGGCGACCGCTGG
AGCCGGACCAGGCTCGCCGCGGCGGGCCTCGGGATCTGGAGCGTCGCCACCGCCGCCGCGGGCCTTGCCCCCACCTATCC
GGCACTGTTGACTGCCCGCACCACGGTCGGGGTCGGTGAAGCGAGCTTCGGCACCGTCTCCCCCGGTCTCCTGGCCGAAT
TTTTCGACCGGGAGCGTCGAGGGCGCATCCTCTCCTACTTCTACCTGGCGATTCCCGTCGGGAGCGCCCTCGGCTATCTC
CTGGGAGGGGTCATCGGCCAGCAATGGGGATGGCATGCCGCGTTCATGATGGTGGGCCTGCCGGGGCTTCTCCTCGTCCT
CCCGGTCTGGCTCATGCGGGAACCGCCCCGCAGCGCCGATGCAGCACTAGAGCAGAACGATAACCCGGACAACGGCGGCT
ACCGCGCCCTGTTCCGGAACCGCTCCTTCATCGCCAACACCCTGGCCATGGCAGCCATGACCTTCGCCCTGGGGGGGCTC
GCCCAGTGGATACCCACCTTCCTCTACCGGGAGCACGGCCTCAGCGTGTCCACCGGTAACACCCTGTTCGGGGGGCTCAC
CGTGGTGACCGGCATCTGCGGCACCCTCACCGGCGGATGGCTCGGCGACCGCCTCCAGCGCCGCACCCCCAAGGGATACC
TCCTGGTCTCGGGCTGGGGGTTCCTCCTGGGGACGCCGGCGGCGGCCTACGCCATCCTGACCCCTTCCCTCAACCACTGC
CTGGGAGGGATGTTCCTGGCCGAGTTTTTCCTCTTCCTCAACACCGGCCCCCTCAACACCGTCATCGTCAACGTTACCCG
CCCGGCCGTCCGCGCCATGGCCTTCGCCGTGAACATCTTCTTCATCCATGCCCTGGGGGACGCAATCTCCCCCACCATCC
TCGGCCGGCTCTCGGACATCTGGGGACTCCGCACTGCCCTCCTCTCCACCCCTGTCGCCATCCTCGTTGCGGCTCTCTTT
GCCTTCGTTTGCTGCCACAGCATCGAAGGGGACATGGCAAAGGCTGAGTAG

Upstream 100 bases:

>100_bases
CCCGAAGGGTTCGGGGTCGAGTTCGTCGGCATCGCAGCCAAGGCCGCCGACCAGGTGAAACGGTACATTGCCGCTTACGT
TCCTCGTTAGGGATCAGCCC

Downstream 100 bases:

>100_bases
CCTCTGGCATCGCCAATCCCCTTCCGTTCCCCCCTGAACTATGCTAATGAAAGGGTTATTTTCCAATCCAGGAGTCAGTC
AATGAAAAAGGACATCCTCG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MHINAPSPPSKSSPYARYVLALLLGVNLLNYIDRQVLYAVFPLIQHDFSLSDTALGLLGSGFMVTYMVSAPLFGWLGDRW
SRTRLAAAGLGIWSVATAAAGLAPTYPALLTARTTVGVGEASFGTVSPGLLAEFFDRERRGRILSYFYLAIPVGSALGYL
LGGVIGQQWGWHAAFMMVGLPGLLLVLPVWLMREPPRSADAALEQNDNPDNGGYRALFRNRSFIANTLAMAAMTFALGGL
AQWIPTFLYREHGLSVSTGNTLFGGLTVVTGICGTLTGGWLGDRLQRRTPKGYLLVSGWGFLLGTPAAAYAILTPSLNHC
LGGMFLAEFFLFLNTGPLNTVIVNVTRPAVRAMAFAVNIFFIHALGDAISPTILGRLSDIWGLRTALLSTPVAILVAALF
AFVCCHSIEGDMAKAE

Sequences:

>Translated_416_residues
MHINAPSPPSKSSPYARYVLALLLGVNLLNYIDRQVLYAVFPLIQHDFSLSDTALGLLGSGFMVTYMVSAPLFGWLGDRW
SRTRLAAAGLGIWSVATAAAGLAPTYPALLTARTTVGVGEASFGTVSPGLLAEFFDRERRGRILSYFYLAIPVGSALGYL
LGGVIGQQWGWHAAFMMVGLPGLLLVLPVWLMREPPRSADAALEQNDNPDNGGYRALFRNRSFIANTLAMAAMTFALGGL
AQWIPTFLYREHGLSVSTGNTLFGGLTVVTGICGTLTGGWLGDRLQRRTPKGYLLVSGWGFLLGTPAAAYAILTPSLNHC
LGGMFLAEFFLFLNTGPLNTVIVNVTRPAVRAMAFAVNIFFIHALGDAISPTILGRLSDIWGLRTALLSTPVAILVAALF
AFVCCHSIEGDMAKAE
>Mature_416_residues
MHINAPSPPSKSSPYARYVLALLLGVNLLNYIDRQVLYAVFPLIQHDFSLSDTALGLLGSGFMVTYMVSAPLFGWLGDRW
SRTRLAAAGLGIWSVATAAAGLAPTYPALLTARTTVGVGEASFGTVSPGLLAEFFDRERRGRILSYFYLAIPVGSALGYL
LGGVIGQQWGWHAAFMMVGLPGLLLVLPVWLMREPPRSADAALEQNDNPDNGGYRALFRNRSFIANTLAMAAMTFALGGL
AQWIPTFLYREHGLSVSTGNTLFGGLTVVTGICGTLTGGWLGDRLQRRTPKGYLLVSGWGFLLGTPAAAYAILTPSLNHC
LGGMFLAEFFLFLNTGPLNTVIVNVTRPAVRAMAFAVNIFFIHALGDAISPTILGRLSDIWGLRTALLSTPVAILVAALF
AFVCCHSIEGDMAKAE

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI215490096, Length=386, Percent_Identity=36.5284974093264, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI14042968, Length=386, Percent_Identity=36.5284974093264, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI185136021, Length=451, Percent_Identity=32.3725055432373, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI215490100, Length=373, Percent_Identity=35.9249329758713, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI194239645, Length=433, Percent_Identity=32.7944572748268, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI215490102, Length=367, Percent_Identity=33.5149863760218, Blast_Score=162, Evalue=8e-40,
Organism=Homo sapiens, GI215490098, Length=367, Percent_Identity=31.6076294277929, Blast_Score=136, Evalue=3e-32,
Organism=Escherichia coli, GI2367379, Length=304, Percent_Identity=24.6710526315789, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1789515, Length=441, Percent_Identity=24.0362811791383, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789152, Length=316, Percent_Identity=23.7341772151899, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082320, Length=430, Percent_Identity=24.1860465116279, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87082404, Length=424, Percent_Identity=21.6981132075472, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082231, Length=220, Percent_Identity=25.4545454545455, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI87081723, Length=270, Percent_Identity=30, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1786686, Length=286, Percent_Identity=25.5244755244755, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71992409, Length=435, Percent_Identity=32.4137931034483, Blast_Score=181, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI193209775, Length=410, Percent_Identity=29.2682926829268, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17557872, Length=404, Percent_Identity=29.9504950495049, Blast_Score=158, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17539092, Length=392, Percent_Identity=29.8469387755102, Blast_Score=151, Evalue=6e-37,
Organism=Drosophila melanogaster, GI17864456, Length=392, Percent_Identity=32.6530612244898, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24654039, Length=392, Percent_Identity=32.6530612244898, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24654041, Length=392, Percent_Identity=32.1428571428571, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24654037, Length=392, Percent_Identity=32.1428571428571, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24654044, Length=262, Percent_Identity=35.1145038167939, Blast_Score=160, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44552; Mature: 44552

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHINAPSPPSKSSPYARYVLALLLGVNLLNYIDRQVLYAVFPLIQHDFSLSDTALGLLGS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
GFMVTYMVSAPLFGWLGDRWSRTRLAAAGLGIWSVATAAAGLAPTYPALLTARTTVGVGE
CHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
ASFGTVSPGLLAEFFDRERRGRILSYFYLAIPVGSALGYLLGGVIGQQWGWHAAFMMVGL
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
PGLLLVLPVWLMREPPRSADAALEQNDNPDNGGYRALFRNRSFIANTLAMAAMTFALGGL
HHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHH
AQWIPTFLYREHGLSVSTGNTLFGGLTVVTGICGTLTGGWLGDRLQRRTPKGYLLVSGWG
HHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCH
FLLGTPAAAYAILTPSLNHCLGGMFLAEFFLFLNTGPLNTVIVNVTRPAVRAMAFAVNIF
HHHCCCHHHHHEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHH
FIHALGDAISPTILGRLSDIWGLRTALLSTPVAILVAALFAFVCCHSIEGDMAKAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MHINAPSPPSKSSPYARYVLALLLGVNLLNYIDRQVLYAVFPLIQHDFSLSDTALGLLGS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
GFMVTYMVSAPLFGWLGDRWSRTRLAAAGLGIWSVATAAAGLAPTYPALLTARTTVGVGE
CHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
ASFGTVSPGLLAEFFDRERRGRILSYFYLAIPVGSALGYLLGGVIGQQWGWHAAFMMVGL
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
PGLLLVLPVWLMREPPRSADAALEQNDNPDNGGYRALFRNRSFIANTLAMAAMTFALGGL
HHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHH
AQWIPTFLYREHGLSVSTGNTLFGGLTVVTGICGTLTGGWLGDRLQRRTPKGYLLVSGWG
HHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCH
FLLGTPAAAYAILTPSLNHCLGGMFLAEFFLFLNTGPLNTVIVNVTRPAVRAMAFAVNIF
HHHCCCHHHHHEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHH
FIHALGDAISPTILGRLSDIWGLRTALLSTPVAILVAALFAFVCCHSIEGDMAKAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]