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The map label for this gene is galT [H]

Identifier: 78224367

GI number: 78224367

Start: 3574468

End: 3575529

Strand: Reverse

Name: galT [H]

Synonym: Gmet_3176

Alternate gene names: 78224367

Gene position: 3575529-3574468 (Counterclockwise)

Preceding gene: 78224368

Following gene: 78224366

Centisome position: 89.45

GC content: 63.47

Gene sequence:

>1062_bases
ATGCGGAGAACTGGCTCATATGAAACTGGAGGAACAATGTCCGAACTGAGATGGGACCCCCTCAAGCAGCACTGGGTGAT
TATCGCCACCGACCGGGGGCGCCGGCCGCGGGATTTCCTCGTGGAGCCCGAGCCCACGGAGATGACCAGCTGTCCCTTCT
GCTACGGCAACGAGGACAAGACCCCCGGCGAGGTGTACGTGGTTCGTCCTGTCGGCGGAGCGAATGCCACCGGGTGGAAG
GTGCGGGTGATCCCGAACCGCTTTCCGGTGCTCCGGATCGAAGGGGAACTCAACAGCCGCGCCTACGGCATCTATGATGT
CATGAACGGCATCGGCGCCCACGAGATCATCATCGAGACACCGGACCACAACCGGGGGCTGGCAGAGCTCTCCCCCGCAG
AGATCACCGAGGTTCTCAAGGCGTACCGCGCCCGTTTCCTGGACCTGCGCCGGGACACGCGGTTCCGCTACATGGTCCTT
TTCAAGAACCACGGCCGGCGGGCCGGGGCCACCCTTTCCCACTCCCACAGCCAGCTCATCGCGGTCCCCCTCATTCCCCC
GGCTGCGGCCACCGAGCTGCGCGTCTGCCGGGAGCACTATGCCAACAAGGAGCGCTGCCTCTTCTGCGACCTGCTCGATT
TCGAGCTCCAGAGCGGCGACCGGATTGTTCGGGAATTCGGCAACTACGTGATCATGACACCCTACGCCTCCTGTTTTCCC
TTCGAGCTGCGGCTCTACCCGAAGCGCCATTCCCACGATTTCGCCCTGTCCACCGACGGCGAACTGGCCGAACTGGCCGT
GGCCCTCAAGGATATGCTCGGCCGGCTCAAGAGCGTCCTCAAGGATCCCCCCTACAACTTCATCCTCCATACCGCGCCCC
CACCGCAGCCGCGGCTCGGCAAGCCGGAATTCTGGAGTTCCATCGAATACGACTACCACTGGCACATCGAGTTGGTGCCA
CGGCTTACCCCCATCGCCGGCTTCGAGTGGGGGACCGGCTTCTACATCAATCCAACCTCGCCGGAAGACGCAGCCACATT
CCTTCGGGGGGCTGAGCTGTAG

Upstream 100 bases:

>100_bases
AAGCTCTTCGCTTTCGTGACCCTCGTCCGCGGAGGCGAAGAGTTTGGTCGCTGGCCCGCCGATTCGCCCCTCGTTCTGAG
CTATGCGGGGCCGGAGCTGG

Downstream 100 bases:

>100_bases
ATGCCCGAAGCCTGACGCCACCTATCGACTCTGAGCCGCTGCGAGGCCCGATAATGAAAATCCTGCAGGTTGCATCCGAG
GTTGCCCCCCTTGCCAAGAC

Product: galactose-1-phosphate uridyl transferase, class I

Products: NA

Alternate protein names: Gal-1-P uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MRRTGSYETGGTMSELRWDPLKQHWVIIATDRGRRPRDFLVEPEPTEMTSCPFCYGNEDKTPGEVYVVRPVGGANATGWK
VRVIPNRFPVLRIEGELNSRAYGIYDVMNGIGAHEIIIETPDHNRGLAELSPAEITEVLKAYRARFLDLRRDTRFRYMVL
FKNHGRRAGATLSHSHSQLIAVPLIPPAAATELRVCREHYANKERCLFCDLLDFELQSGDRIVREFGNYVIMTPYASCFP
FELRLYPKRHSHDFALSTDGELAELAVALKDMLGRLKSVLKDPPYNFILHTAPPPQPRLGKPEFWSSIEYDYHWHIELVP
RLTPIAGFEWGTGFYINPTSPEDAATFLRGAEL

Sequences:

>Translated_353_residues
MRRTGSYETGGTMSELRWDPLKQHWVIIATDRGRRPRDFLVEPEPTEMTSCPFCYGNEDKTPGEVYVVRPVGGANATGWK
VRVIPNRFPVLRIEGELNSRAYGIYDVMNGIGAHEIIIETPDHNRGLAELSPAEITEVLKAYRARFLDLRRDTRFRYMVL
FKNHGRRAGATLSHSHSQLIAVPLIPPAAATELRVCREHYANKERCLFCDLLDFELQSGDRIVREFGNYVIMTPYASCFP
FELRLYPKRHSHDFALSTDGELAELAVALKDMLGRLKSVLKDPPYNFILHTAPPPQPRLGKPEFWSSIEYDYHWHIELVP
RLTPIAGFEWGTGFYINPTSPEDAATFLRGAEL
>Mature_353_residues
MRRTGSYETGGTMSELRWDPLKQHWVIIATDRGRRPRDFLVEPEPTEMTSCPFCYGNEDKTPGEVYVVRPVGGANATGWK
VRVIPNRFPVLRIEGELNSRAYGIYDVMNGIGAHEIIIETPDHNRGLAELSPAEITEVLKAYRARFLDLRRDTRFRYMVL
FKNHGRRAGATLSHSHSQLIAVPLIPPAAATELRVCREHYANKERCLFCDLLDFELQSGDRIVREFGNYVIMTPYASCFP
FELRLYPKRHSHDFALSTDGELAELAVALKDMLGRLKSVLKDPPYNFILHTAPPPQPRLGKPEFWSSIEYDYHWHIELVP
RLTPIAGFEWGTGFYINPTSPEDAATFLRGAEL

Specific function: Galactose metabolism; second step. [C]

COG id: COG1085

COG function: function code C; Galactose-1-phosphate uridylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family [H]

Homologues:

Organism=Homo sapiens, GI22165416, Length=285, Percent_Identity=22.8070175438596, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1786973, Length=284, Percent_Identity=27.4647887323944, Blast_Score=116, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17557105, Length=299, Percent_Identity=23.0769230769231, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319492, Length=305, Percent_Identity=22.6229508196721, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24582285, Length=288, Percent_Identity=24.3055555555556, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001937
- InterPro:   IPR019779
- InterPro:   IPR005850
- InterPro:   IPR005849
- InterPro:   IPR011146
- InterPro:   IPR011151 [H]

Pfam domain/function: PF02744 GalP_UDP_tr_C; PF01087 GalP_UDP_transf [H]

EC number: =2.7.7.12 [H]

Molecular weight: Translated: 40306; Mature: 40306

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRTGSYETGGTMSELRWDPLKQHWVIIATDRGRRPRDFLVEPEPTEMTSCPFCYGNEDK
CCCCCCCCCCCCHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCC
TPGEVYVVRPVGGANATGWKVRVIPNRFPVLRIEGELNSRAYGIYDVMNGIGAHEIIIET
CCCEEEEEEECCCCCCCCEEEEECCCCCCEEEEECCCCCCEEEHHHHHCCCCCEEEEEEC
PDHNRGLAELSPAEITEVLKAYRARFLDLRRDTRFRYMVLFKNHGRRAGATLSHSHSQLI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEECCCCCEE
AVPLIPPAAATELRVCREHYANKERCLFCDLLDFELQSGDRIVREFGNYVIMTPYASCFP
EEECCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHCCEEEECCCCCCCC
FELRLYPKRHSHDFALSTDGELAELAVALKDMLGRLKSVLKDPPYNFILHTAPPPQPRLG
EEEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCC
KPEFWSSIEYDYHWHIELVPRLTPIAGFEWGTGFYINPTSPEDAATFLRGAEL
CCHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCEEECCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MRRTGSYETGGTMSELRWDPLKQHWVIIATDRGRRPRDFLVEPEPTEMTSCPFCYGNEDK
CCCCCCCCCCCCHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCC
TPGEVYVVRPVGGANATGWKVRVIPNRFPVLRIEGELNSRAYGIYDVMNGIGAHEIIIET
CCCEEEEEEECCCCCCCCEEEEECCCCCCEEEEECCCCCCEEEHHHHHCCCCCEEEEEEC
PDHNRGLAELSPAEITEVLKAYRARFLDLRRDTRFRYMVLFKNHGRRAGATLSHSHSQLI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEECCCCCEE
AVPLIPPAAATELRVCREHYANKERCLFCDLLDFELQSGDRIVREFGNYVIMTPYASCFP
EEECCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHCCEEEECCCCCCCC
FELRLYPKRHSHDFALSTDGELAELAVALKDMLGRLKSVLKDPPYNFILHTAPPPQPRLG
EEEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCC
KPEFWSSIEYDYHWHIELVPRLTPIAGFEWGTGFYINPTSPEDAATFLRGAEL
CCHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCEEECCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9741105; 10360571 [H]