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The map label for this gene is bvgS [H]

Identifier: 78224191

GI number: 78224191

Start: 3382094

End: 3384517

Strand: Direct

Name: bvgS [H]

Synonym: Gmet_2998

Alternate gene names: 78224191

Gene position: 3382094-3384517 (Clockwise)

Preceding gene: 78224190

Following gene: 78224192

Centisome position: 84.61

GC content: 57.71

Gene sequence:

>2424_bases
ATGGGCAACGATATGAGAAACGACGTCAAATCACTCCGTGCGGGCATATTCTCAGAAATCATCATCGTCTTCCTCCCCCT
GACGATGCTGCTCATCTATCAGACCGTCAGCGACATCACCGTCTCCGACAGGCTTGCCGACACCCATCGGCTCCTTGCCG
CCTCGTCGTCGGCCTACCAGAGATACAGACTGTTCGTCAACGGCGTCGTTGATGCGATCGATACCGGCAGAGTCTCCGAG
GATGCCGTCCACAACCTCGAACATACAACCGTTGAACTCAAGTCCATCACCACCGGGGACCGCAGCAGTGATTTCAGTTC
CCTGGCGGCCAGGACAAACGCCCTGCTCGCGCACCTGAGGAAAGACCGCTCCTTCGGGAAGGTACTGCCGCTGCGGGATA
CCATCAATGGGATCGATGCGGACCTGTCGGCGCTTGCCGCACAATGCGACGAAACAAATCGACAAATGATCCTGGAGAAC
ATCAATTCCACCCAGTCCAGAAAGATCATGGTGTTCACGGCCCTGGCACTGGGAGCACTCGTCACACTTGCCCTGATTGT
CATGCTTATTCGGCATGTTACCCGGTTCGAGCTGGTCTTGCGGGAGAGCGAAGAGCGAATGCGGGTAATGTTCGAGTCGA
TCAACGCCGGCATTGTGCTCATCGATTGCGATAACAACAGCATCGTGGATGTCAATCCGACTGCGCTTCGCCTGCACGGG
GGAACAAAGGAGGAATTGATAGGGTATCCGAGTGAGCGTCTCTTCCATGGGGACAATGTGCGGACAGATCCGGAGCATGA
CGAGGGGAAGGCAATCGACATATCCAAGGGGATGTTGAGCCTGTGCAATGGCGAACGCCTTCCCGTCCTTGAATCGGTCA
ACTACGTGGCCATAAACGGTCGCCGGTATATGCTGAAAAGCTTTGTCGACCTGTCGAAACAGATGACCCTGGAAACCGAG
CTCCTTGCCGCCAAGGAGGCTGCCGAGGCGGCCAGCAGGGCCAAAAGCATATTTCTCGCCAGCATGAGCCATGAAATCCG
GACTCCCATGAACGCTATCATCGGCTATGCGCAACTGCTGAAGCGAGAAGGCAATCTTGCGCCACAACAGGGACAATACC
TCAATGTCATCAACAACAGCGGAGAGCATCTCCTCAAGCTGATCAACGACATTCTCGAAATGTCGAAAATCGAGTCCGGC
ACGGTCAACCTCACGCCGGTTCCCTTCAATTTTCACAATCTGCTGCACGACGTGGAATCCCTGTTCGCCGACCGGGCCAG
GCAGAAGAAGCTGCGGTTCGACGTCCGGTTGCAGGGCGAGGTACCCGTGGTGCTGGATGCGGATGAGATGAAAGTGCGCC
AGGTCCTCATCAACATGATCGGCAACGCGCTCAAATTCACCGACGAGGGGACGATTGCCGTCACGGTTTCCTCCTCGACC
GACAGCCCGGACAAAGAACGTGACACGTACGGCGAAACGGCCATAACCGTCGATGTCGAAGACTCGGGAATCGGAATCTC
TGCCGAGGAGGCAGACCAAGTCTTTGCCCTGTTCGAGCAGACCGAAAGCGGCCGACGCAGGATAGGAGGAACGGGACTCG
GCATGCCAATCAGCCGCCAGTTCGCCCGACTGATGGGAGGAGACCTGTTTCTTGTGCGCGGCGAGCCCGGCATCGGCTCG
GCATTCCGTTTTGTCTTCAGGGCAAAGGCGCTGGACCTGGCGGAATTCAAGCAGCCGGCAGTCGATGAGCGGTTCTTCTG
GCGGATTATCCCGGACGAAAAAGAATGGCGCGTCCTGGTCGTCGATGACCAGGAGAACAACCGGAGCCTTTTGTCGCACA
TGCTCACCAGGGCCGGCTTTGCGGTTCGCGAGGCGGACGGCGGCATTGACGGCGTCGCCCAGTTTCGCGCCTGGCTTCCC
GATATCGTTCTGATGGATATCCTGATGCCGGATATGGACGGCTATGAGGCCCTGCGGCAGATAAAGGCAACCTCAGAGGG
GGGCGTTACCCCCGTAATCGCCGTTACCGCCAGCGTCATGATGGATGAACATCAGAAGGCCCTCGATCTTGGATTTGACG
GTTTCATCATGAAGCCGGTTTCCATGGAGTGCCTCTTCGAGGAAATCCGGCGTCTCACCAACGTGGCCTATCTGTACGAT
GACAGCAGGTCCTCCGGGGATGCGGCCGCGGAGATCCTTCCCCCCTGGGTTGACAGGCTGACCACGCTGCCGGACGTTCT
CCTGGGGGCCATGCGTGATGCGCTTGAGGCGGGAGACATTGCTTCACTTCGGGGGCTCATCGAGCAGATAGGCGAGTCCG
AACCGATACCGGCCGAAGCGTTACGCCGCCTTGTCGATTCTTATTCCTACGACGAACTGACCACACTGCTTGCAGGGGGG
GACGCCAGATATGCCAGCGCTTGA

Upstream 100 bases:

>100_bases
CTGGTGATACTGAAACCATTGAATTCGTGAGGAAAACACCCGGAGCGGTTGGCTATGTGAGAGTCCTCCCCAAAGGGCTC
AAGGTTATCAGGTCCTATTG

Downstream 100 bases:

>100_bases
GCAGCCGCCCAATATCATGATAGTGGACGACACTCCTGCCAATCTCCGGCTTCTTGAAACGATGCTGCAGGAAAAGAATT
ACCGCGTGCTGTTGTTTCCA

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 807; Mature: 806

Protein sequence:

>807_residues
MGNDMRNDVKSLRAGIFSEIIIVFLPLTMLLIYQTVSDITVSDRLADTHRLLAASSSAYQRYRLFVNGVVDAIDTGRVSE
DAVHNLEHTTVELKSITTGDRSSDFSSLAARTNALLAHLRKDRSFGKVLPLRDTINGIDADLSALAAQCDETNRQMILEN
INSTQSRKIMVFTALALGALVTLALIVMLIRHVTRFELVLRESEERMRVMFESINAGIVLIDCDNNSIVDVNPTALRLHG
GTKEELIGYPSERLFHGDNVRTDPEHDEGKAIDISKGMLSLCNGERLPVLESVNYVAINGRRYMLKSFVDLSKQMTLETE
LLAAKEAAEAASRAKSIFLASMSHEIRTPMNAIIGYAQLLKREGNLAPQQGQYLNVINNSGEHLLKLINDILEMSKIESG
TVNLTPVPFNFHNLLHDVESLFADRARQKKLRFDVRLQGEVPVVLDADEMKVRQVLINMIGNALKFTDEGTIAVTVSSST
DSPDKERDTYGETAITVDVEDSGIGISAEEADQVFALFEQTESGRRRIGGTGLGMPISRQFARLMGGDLFLVRGEPGIGS
AFRFVFRAKALDLAEFKQPAVDERFFWRIIPDEKEWRVLVVDDQENNRSLLSHMLTRAGFAVREADGGIDGVAQFRAWLP
DIVLMDILMPDMDGYEALRQIKATSEGGVTPVIAVTASVMMDEHQKALDLGFDGFIMKPVSMECLFEEIRRLTNVAYLYD
DSRSSGDAAAEILPPWVDRLTTLPDVLLGAMRDALEAGDIASLRGLIEQIGESEPIPAEALRRLVDSYSYDELTTLLAGG
DARYASA

Sequences:

>Translated_807_residues
MGNDMRNDVKSLRAGIFSEIIIVFLPLTMLLIYQTVSDITVSDRLADTHRLLAASSSAYQRYRLFVNGVVDAIDTGRVSE
DAVHNLEHTTVELKSITTGDRSSDFSSLAARTNALLAHLRKDRSFGKVLPLRDTINGIDADLSALAAQCDETNRQMILEN
INSTQSRKIMVFTALALGALVTLALIVMLIRHVTRFELVLRESEERMRVMFESINAGIVLIDCDNNSIVDVNPTALRLHG
GTKEELIGYPSERLFHGDNVRTDPEHDEGKAIDISKGMLSLCNGERLPVLESVNYVAINGRRYMLKSFVDLSKQMTLETE
LLAAKEAAEAASRAKSIFLASMSHEIRTPMNAIIGYAQLLKREGNLAPQQGQYLNVINNSGEHLLKLINDILEMSKIESG
TVNLTPVPFNFHNLLHDVESLFADRARQKKLRFDVRLQGEVPVVLDADEMKVRQVLINMIGNALKFTDEGTIAVTVSSST
DSPDKERDTYGETAITVDVEDSGIGISAEEADQVFALFEQTESGRRRIGGTGLGMPISRQFARLMGGDLFLVRGEPGIGS
AFRFVFRAKALDLAEFKQPAVDERFFWRIIPDEKEWRVLVVDDQENNRSLLSHMLTRAGFAVREADGGIDGVAQFRAWLP
DIVLMDILMPDMDGYEALRQIKATSEGGVTPVIAVTASVMMDEHQKALDLGFDGFIMKPVSMECLFEEIRRLTNVAYLYD
DSRSSGDAAAEILPPWVDRLTTLPDVLLGAMRDALEAGDIASLRGLIEQIGESEPIPAEALRRLVDSYSYDELTTLLAGG
DARYASA
>Mature_806_residues
GNDMRNDVKSLRAGIFSEIIIVFLPLTMLLIYQTVSDITVSDRLADTHRLLAASSSAYQRYRLFVNGVVDAIDTGRVSED
AVHNLEHTTVELKSITTGDRSSDFSSLAARTNALLAHLRKDRSFGKVLPLRDTINGIDADLSALAAQCDETNRQMILENI
NSTQSRKIMVFTALALGALVTLALIVMLIRHVTRFELVLRESEERMRVMFESINAGIVLIDCDNNSIVDVNPTALRLHGG
TKEELIGYPSERLFHGDNVRTDPEHDEGKAIDISKGMLSLCNGERLPVLESVNYVAINGRRYMLKSFVDLSKQMTLETEL
LAAKEAAEAASRAKSIFLASMSHEIRTPMNAIIGYAQLLKREGNLAPQQGQYLNVINNSGEHLLKLINDILEMSKIESGT
VNLTPVPFNFHNLLHDVESLFADRARQKKLRFDVRLQGEVPVVLDADEMKVRQVLINMIGNALKFTDEGTIAVTVSSSTD
SPDKERDTYGETAITVDVEDSGIGISAEEADQVFALFEQTESGRRRIGGTGLGMPISRQFARLMGGDLFLVRGEPGIGSA
FRFVFRAKALDLAEFKQPAVDERFFWRIIPDEKEWRVLVVDDQENNRSLLSHMLTRAGFAVREADGGIDGVAQFRAWLPD
IVLMDILMPDMDGYEALRQIKATSEGGVTPVIAVTASVMMDEHQKALDLGFDGFIMKPVSMECLFEEIRRLTNVAYLYDD
SRSSGDAAAEILPPWVDRLTTLPDVLLGAMRDALEAGDIASLRGLIEQIGESEPIPAEALRRLVDSYSYDELTTLLAGGD
ARYASA

Specific function: Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=410, Percent_Identity=35.1219512195122, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1788713, Length=499, Percent_Identity=30.2605210420842, Blast_Score=192, Evalue=9e-50,
Organism=Escherichia coli, GI87081816, Length=422, Percent_Identity=34.1232227488152, Blast_Score=170, Evalue=3e-43,
Organism=Escherichia coli, GI1789149, Length=255, Percent_Identity=38.0392156862745, Blast_Score=170, Evalue=4e-43,
Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=36.328125, Blast_Score=158, Evalue=1e-39,
Organism=Escherichia coli, GI1788549, Length=387, Percent_Identity=25.0645994832041, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI87082128, Length=237, Percent_Identity=29.535864978903, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1786600, Length=275, Percent_Identity=25.8181818181818, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=37.6146788990826, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786912, Length=315, Percent_Identity=24.7619047619048, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786784, Length=116, Percent_Identity=30.1724137931034, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790436, Length=263, Percent_Identity=25.0950570342205, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=33.0578512396694, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788393, Length=213, Percent_Identity=25.8215962441315, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1787487, Length=157, Percent_Identity=28.0254777070064, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790346, Length=202, Percent_Identity=28.7128712871287, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 89266; Mature: 89135

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNDMRNDVKSLRAGIFSEIIIVFLPLTMLLIYQTVSDITVSDRLADTHRLLAASSSAYQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHH
RYRLFVNGVVDAIDTGRVSEDAVHNLEHTTVELKSITTGDRSSDFSSLAARTNALLAHLR
HHHHHHHHHHHHHCCCCCCHHHHHCCHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
KDRSFGKVLPLRDTINGIDADLSALAAQCDETNRQMILENINSTQSRKIMVFTALALGAL
HCCCCCCEECCHHHCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCEEEEHHHHHHHHH
VTLALIVMLIRHVTRFELVLRESEERMRVMFESINAGIVLIDCDNNSIVDVNPTALRLHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCEEEECC
GTKEELIGYPSERLFHGDNVRTDPEHDEGKAIDISKGMLSLCNGERLPVLESVNYVAING
CCHHHHCCCCHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCHHHCCCEEEECC
RRYMLKSFVDLSKQMTLETELLAAKEAAEAASRAKSIFLASMSHEIRTPMNAIIGYAQLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
KREGNLAPQQGQYLNVINNSGEHLLKLINDILEMSKIESGTVNLTPVPFNFHNLLHDVES
HHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHH
LFADRARQKKLRFDVRLQGEVPVVLDADEMKVRQVLINMIGNALKFTDEGTIAVTVSSST
HHHHHHHHHHCEEEEEECCCCCEEECCHHHHHHHHHHHHHCCCEEECCCCEEEEEEECCC
DSPDKERDTYGETAITVDVEDSGIGISAEEADQVFALFEQTESGRRRIGGTGLGMPISRQ
CCCCCHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
FARLMGGDLFLVRGEPGIGSAFRFVFRAKALDLAEFKQPAVDERFFWRIIPDEKEWRVLV
HHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEE
VDDQENNRSLLSHMLTRAGFAVREADGGIDGVAQFRAWLPDIVLMDILMPDMDGYEALRQ
EECCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IKATSEGGVTPVIAVTASVMMDEHQKALDLGFDGFIMKPVSMECLFEEIRRLTNVAYLYD
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHEEEEEE
DSRSSGDAAAEILPPWVDRLTTLPDVLLGAMRDALEAGDIASLRGLIEQIGESEPIPAEA
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHH
LRRLVDSYSYDELTTLLAGGDARYASA
HHHHHHCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
GNDMRNDVKSLRAGIFSEIIIVFLPLTMLLIYQTVSDITVSDRLADTHRLLAASSSAYQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHH
RYRLFVNGVVDAIDTGRVSEDAVHNLEHTTVELKSITTGDRSSDFSSLAARTNALLAHLR
HHHHHHHHHHHHHCCCCCCHHHHHCCHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
KDRSFGKVLPLRDTINGIDADLSALAAQCDETNRQMILENINSTQSRKIMVFTALALGAL
HCCCCCCEECCHHHCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCEEEEHHHHHHHHH
VTLALIVMLIRHVTRFELVLRESEERMRVMFESINAGIVLIDCDNNSIVDVNPTALRLHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCEEEECC
GTKEELIGYPSERLFHGDNVRTDPEHDEGKAIDISKGMLSLCNGERLPVLESVNYVAING
CCHHHHCCCCHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCHHHCCCEEEECC
RRYMLKSFVDLSKQMTLETELLAAKEAAEAASRAKSIFLASMSHEIRTPMNAIIGYAQLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
KREGNLAPQQGQYLNVINNSGEHLLKLINDILEMSKIESGTVNLTPVPFNFHNLLHDVES
HHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHH
LFADRARQKKLRFDVRLQGEVPVVLDADEMKVRQVLINMIGNALKFTDEGTIAVTVSSST
HHHHHHHHHHCEEEEEECCCCCEEECCHHHHHHHHHHHHHCCCEEECCCCEEEEEEECCC
DSPDKERDTYGETAITVDVEDSGIGISAEEADQVFALFEQTESGRRRIGGTGLGMPISRQ
CCCCCHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
FARLMGGDLFLVRGEPGIGSAFRFVFRAKALDLAEFKQPAVDERFFWRIIPDEKEWRVLV
HHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEE
VDDQENNRSLLSHMLTRAGFAVREADGGIDGVAQFRAWLPDIVLMDILMPDMDGYEALRQ
EECCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IKATSEGGVTPVIAVTASVMMDEHQKALDLGFDGFIMKPVSMECLFEEIRRLTNVAYLYD
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHEEEEEE
DSRSSGDAAAEILPPWVDRLTTLPDVLLGAMRDALEAGDIASLRGLIEQIGESEPIPAEA
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHH
LRRLVDSYSYDELTTLLAGGDARYASA
HHHHHHCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]