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The map label for this gene is ppdK [H]

Identifier: 78224136

GI number: 78224136

Start: 3327578

End: 3330244

Strand: Reverse

Name: ppdK [H]

Synonym: Gmet_2940

Alternate gene names: 78224136

Gene position: 3330244-3327578 (Counterclockwise)

Preceding gene: 78224137

Following gene: 78224135

Centisome position: 83.31

GC content: 64.27

Gene sequence:

>2667_bases
ATGGCTGAAAAGTATGTCTATTTCTTCGGGAACGGCAAGGCAGAGGGCAAAGCCGACATGAAGAACCTGCTGGGGGGCAA
GGGGGCCAACCTGGCGGAGATGACCGCGATCGGACTGCCGGTTCCCCCCGGCTTCACCATCACCACCGAGGTCTGCACCT
ACTACTACGCCAACAATAAGAGCTATCCGTCGGTCCTGGCCGCCCAGGTGGCCGAGAACCTGAAAAGTGTAGAGGCCATC
ATGGGGCGTACCTTCGGTGACCCGAAGAATCCCCTTCTGGTTTCGGTCCGTTCAGGCGCCCGGGCCTCCATGCCGGGGAT
GATGGATACGATCCTCAACCTGGGACTAAACGACGAGACAGTGCAGGGGATCATCGTCCAGAGCGGTGACGAGCGCTTTG
CCTACGACGCCTACCGCCGTTTCGTCCAGATGTACTCCGACGTGGTCATGGGGATGGACAAGGAGGCTCTGGAGCACCTG
CTGGAGGAGAAGAAGGCGGCGAAGGGGGTTCACCTGGACACCGACCTCACCGCCGCCGACTGGAAGGAGCTGGTGGGGGC
CTTCAAGGCCAAGATCAGGGAGACCCTCGGCACCGCGTTCCCGGAGAATCCCCAGGAGCAGCTCTGGGGGGCCGTGGGCG
CCGTGTTCGGCTCGTGGATGAACCAGCGGGCCATCACCTACCGCCGCCTCAACGGCATCCCCGCCGACTGGGGGACCGCC
GTCAACGTCCAGTCCATGGTCTACGGCAACATGGGGAACGACTGCGCCACCGGCGTCGCCTTCACCCGGGACCCATCCAC
CGGCGAGAACTACTTCTACGGCGAGTACCTGGTGAACGCCCAGGGCGAGGACGTGGTTGCCGGCATTCGGACCCCCCAGC
CCATCAACCGCGCCAACAGCAAGGACGCGACTCTCCCCTCCATGGAAGAGGTGCTTCCCGAGTGCTACCAGCAGCTGGTC
CAGATCCGCGGCATCCTGGAGAAGCATTACAGGGACATGCAGGACATCGAGTTCACCATCGAGAAGGGGAAGCTCTTCAT
GCTCCAGACCCGCAACGGTAAGCGGACCGCCAAGGCGGCCATCAAGGTTGCCGTGGACATGGTGAAGGAGGGGCTCATCG
ACGAGAAGACCGCCGTGCTGCGGGTCTCTCCCTCCCAGCTGGATCAGCTCCTCCACCCCTCCCTCGATCCCAAGGCTCCC
AGGACGATTATCGCCAAGGGGCTTCCCGCATCGCCGGGGGCGGCATCGGGCGAGGTGGTCTTCACCGCCGACGAGGCCGA
GGCCGCCGGTCGCCTGGGGCTCAAGGTCATCCTCGTTCGGATCGAGACCTCTCCGGAAGATATCCACGGCATGCATGCGG
CCCAGGGGATCCTCACCGCCCGGGGGGGCATGACCTCCCACGCGGCGGTCGTTGCCCGCGGCATGGGCAAGTGCTGCGTT
GCCGGCTGCGGCGACATCAAGGTGGACTACGCCGCCGGCCAGTTCGTGACCGCCAAGGGGCAGGTGGTGAAAAGGGGCGA
CACGATCACCCTTGACGGTTCCACCGGAGAGGTGATGCTCGGCGAGGTCCCCACCGTGGCGCCACAGCTCACCGGCGACT
TCGGCGTTCTCATGGGATGGGTCGACACCTACCGCAAGCTCAAGGTGCGGACCAACGCCGACACTCCCAACGATTCCCGC
GTGGCCCGCGAGTTCGGGGCCGAGGGGATCGGCCTCTGCCGCACCGAGCACATGTTCTTCGAGGCGGACCGGATCGCGGC
CGTCCGTGAGATGATCCTCTCCGAGGACGTGGAAGGGCGCACGAAGGCCCTGGCCAAGATCCTCCCCATGCAGAAGGGGG
ACTTCCTCGGTATCTTCCGGGAGATGAAGGACCTGCCGGTCACCATTCGCCTCCTGGACCCGCCGCTCCATGAGTTCCTC
CCCCAGGAGGAGAAGGACGTGGATGCCCTGGCCAAGACCATGGGGGTGACGGCCCAGACCCTCAAGAACAAGGTGGACTA
CCTCCACGAGTTCAACCCGATGCTGGGGCACCGGGGGTGCCGTCTGGGGCTCACCTTCCCGGAGATCTACGACATGCAGG
TCCAGGCCATCATGGAGGCCGCCTGCGAGCTGACCAAGAACGAAGGGTTCACTATCGTCCCCGAGATCATGATCCCGCTG
GTGGGGGTGGTGAGCGAGCTGGCGCGGCTTCGTGAAAACACCGTCCGGGTATGCGAGGAGGTCATCGCTCGTTACGGCGT
GAAGATCGACTACCTCATCGGCACCATGATCGAGCTTCCCCGGGCCGCCCTGACCGCCGACGAGATTGCCCGTGAGGCAG
ACTTTTTCTCCTTCGGCACCAACGACCTGACCCAGACTACCTTCGGCCTTTCCCGTGACGATGCCGGCAAGTTCCTGCCG
TTCTATGTGGAATCGGGGCTGTTGGAAGAGGATCCCTTCGTCTCCCTGGACCAGAACGGCGTCGGTATTCTCGTGAAGAT
GGCCGTGGAGAAGGGGCGCACCACCCGCGCCGGCATCAAGCTCGGCATCTGCGGCGAGCATGGCGGCGACCCGTCGTCGG
TCATTTTCTGCCACAAGATCGGCCTTGATTATGTCTCCTGCTCCCCCTTCCGGGTGCCCATCGCCCGCCTCGCCGCTGCC
CATGCTGCTCTGGGTGAAGGGAACTGA

Upstream 100 bases:

>100_bases
ATCTCTGTTGAGTTACGCTTAATCACATTTAATGCAGCTGAAGGGTTTTGACTTTCAGTAAACGGCGGTGTCACCGTCAC
AACCACAGAGGAGGAGTGCA

Downstream 100 bases:

>100_bases
ACCTCCGTTAGTCTTCCGTTTGCAAAGAAAGCCCCGGTCACGCCGGGGCTTTCTTTGTTGAGCCTGCCCGTAACACTTCG
TAATCCTGTCTAAACTAATT

Product: pyruvate phosphate dikinase

Products: NA

Alternate protein names: Pyruvate, orthophosphate dikinase [H]

Number of amino acids: Translated: 888; Mature: 887

Protein sequence:

>888_residues
MAEKYVYFFGNGKAEGKADMKNLLGGKGANLAEMTAIGLPVPPGFTITTEVCTYYYANNKSYPSVLAAQVAENLKSVEAI
MGRTFGDPKNPLLVSVRSGARASMPGMMDTILNLGLNDETVQGIIVQSGDERFAYDAYRRFVQMYSDVVMGMDKEALEHL
LEEKKAAKGVHLDTDLTAADWKELVGAFKAKIRETLGTAFPENPQEQLWGAVGAVFGSWMNQRAITYRRLNGIPADWGTA
VNVQSMVYGNMGNDCATGVAFTRDPSTGENYFYGEYLVNAQGEDVVAGIRTPQPINRANSKDATLPSMEEVLPECYQQLV
QIRGILEKHYRDMQDIEFTIEKGKLFMLQTRNGKRTAKAAIKVAVDMVKEGLIDEKTAVLRVSPSQLDQLLHPSLDPKAP
RTIIAKGLPASPGAASGEVVFTADEAEAAGRLGLKVILVRIETSPEDIHGMHAAQGILTARGGMTSHAAVVARGMGKCCV
AGCGDIKVDYAAGQFVTAKGQVVKRGDTITLDGSTGEVMLGEVPTVAPQLTGDFGVLMGWVDTYRKLKVRTNADTPNDSR
VAREFGAEGIGLCRTEHMFFEADRIAAVREMILSEDVEGRTKALAKILPMQKGDFLGIFREMKDLPVTIRLLDPPLHEFL
PQEEKDVDALAKTMGVTAQTLKNKVDYLHEFNPMLGHRGCRLGLTFPEIYDMQVQAIMEAACELTKNEGFTIVPEIMIPL
VGVVSELARLRENTVRVCEEVIARYGVKIDYLIGTMIELPRAALTADEIAREADFFSFGTNDLTQTTFGLSRDDAGKFLP
FYVESGLLEEDPFVSLDQNGVGILVKMAVEKGRTTRAGIKLGICGEHGGDPSSVIFCHKIGLDYVSCSPFRVPIARLAAA
HAALGEGN

Sequences:

>Translated_888_residues
MAEKYVYFFGNGKAEGKADMKNLLGGKGANLAEMTAIGLPVPPGFTITTEVCTYYYANNKSYPSVLAAQVAENLKSVEAI
MGRTFGDPKNPLLVSVRSGARASMPGMMDTILNLGLNDETVQGIIVQSGDERFAYDAYRRFVQMYSDVVMGMDKEALEHL
LEEKKAAKGVHLDTDLTAADWKELVGAFKAKIRETLGTAFPENPQEQLWGAVGAVFGSWMNQRAITYRRLNGIPADWGTA
VNVQSMVYGNMGNDCATGVAFTRDPSTGENYFYGEYLVNAQGEDVVAGIRTPQPINRANSKDATLPSMEEVLPECYQQLV
QIRGILEKHYRDMQDIEFTIEKGKLFMLQTRNGKRTAKAAIKVAVDMVKEGLIDEKTAVLRVSPSQLDQLLHPSLDPKAP
RTIIAKGLPASPGAASGEVVFTADEAEAAGRLGLKVILVRIETSPEDIHGMHAAQGILTARGGMTSHAAVVARGMGKCCV
AGCGDIKVDYAAGQFVTAKGQVVKRGDTITLDGSTGEVMLGEVPTVAPQLTGDFGVLMGWVDTYRKLKVRTNADTPNDSR
VAREFGAEGIGLCRTEHMFFEADRIAAVREMILSEDVEGRTKALAKILPMQKGDFLGIFREMKDLPVTIRLLDPPLHEFL
PQEEKDVDALAKTMGVTAQTLKNKVDYLHEFNPMLGHRGCRLGLTFPEIYDMQVQAIMEAACELTKNEGFTIVPEIMIPL
VGVVSELARLRENTVRVCEEVIARYGVKIDYLIGTMIELPRAALTADEIAREADFFSFGTNDLTQTTFGLSRDDAGKFLP
FYVESGLLEEDPFVSLDQNGVGILVKMAVEKGRTTRAGIKLGICGEHGGDPSSVIFCHKIGLDYVSCSPFRVPIARLAAA
HAALGEGN
>Mature_887_residues
AEKYVYFFGNGKAEGKADMKNLLGGKGANLAEMTAIGLPVPPGFTITTEVCTYYYANNKSYPSVLAAQVAENLKSVEAIM
GRTFGDPKNPLLVSVRSGARASMPGMMDTILNLGLNDETVQGIIVQSGDERFAYDAYRRFVQMYSDVVMGMDKEALEHLL
EEKKAAKGVHLDTDLTAADWKELVGAFKAKIRETLGTAFPENPQEQLWGAVGAVFGSWMNQRAITYRRLNGIPADWGTAV
NVQSMVYGNMGNDCATGVAFTRDPSTGENYFYGEYLVNAQGEDVVAGIRTPQPINRANSKDATLPSMEEVLPECYQQLVQ
IRGILEKHYRDMQDIEFTIEKGKLFMLQTRNGKRTAKAAIKVAVDMVKEGLIDEKTAVLRVSPSQLDQLLHPSLDPKAPR
TIIAKGLPASPGAASGEVVFTADEAEAAGRLGLKVILVRIETSPEDIHGMHAAQGILTARGGMTSHAAVVARGMGKCCVA
GCGDIKVDYAAGQFVTAKGQVVKRGDTITLDGSTGEVMLGEVPTVAPQLTGDFGVLMGWVDTYRKLKVRTNADTPNDSRV
AREFGAEGIGLCRTEHMFFEADRIAAVREMILSEDVEGRTKALAKILPMQKGDFLGIFREMKDLPVTIRLLDPPLHEFLP
QEEKDVDALAKTMGVTAQTLKNKVDYLHEFNPMLGHRGCRLGLTFPEIYDMQVQAIMEAACELTKNEGFTIVPEIMIPLV
GVVSELARLRENTVRVCEEVIARYGVKIDYLIGTMIELPRAALTADEIAREADFFSFGTNDLTQTTFGLSRDDAGKFLPF
YVESGLLEEDPFVSLDQNGVGILVKMAVEKGRTTRAGIKLGICGEHGGDPSSVIFCHKIGLDYVSCSPFRVPIARLAAAH
AALGEGN

Specific function: Catalyzes the reversible phosphorylation of pyruvate and phosphate [H]

COG id: COG0574

COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEP-utilizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1787994, Length=728, Percent_Identity=25.9615384615385, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI1788756, Length=457, Percent_Identity=25.8205689277899, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1789193, Length=427, Percent_Identity=26.2295081967213, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788726, Length=602, Percent_Identity=22.4252491694352, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI48994992, Length=469, Percent_Identity=23.8805970149254, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR008279
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR002192
- InterPro:   IPR010121
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]

EC number: =2.7.9.1 [H]

Molecular weight: Translated: 96617; Mature: 96486

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE ; PS00742 PEP_ENZYMES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKYVYFFGNGKAEGKADMKNLLGGKGANLAEMTAIGLPVPPGFTITTEVCTYYYANNK
CCCEEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHEECCCCCCCCEEHHHHEEEEEECCC
SYPSVLAAQVAENLKSVEAIMGRTFGDPKNPLLVSVRSGARASMPGMMDTILNLGLNDET
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCHH
VQGIIVQSGDERFAYDAYRRFVQMYSDVVMGMDKEALEHLLEEKKAAKGVHLDTDLTAAD
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHH
WKELVGAFKAKIRETLGTAFPENPQEQLWGAVGAVFGSWMNQRAITYRRLNGIPADWGTA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VNVQSMVYGNMGNDCATGVAFTRDPSTGENYFYGEYLVNAQGEDVVAGIRTPQPINRANS
EEEHHHEECCCCCCHHCCCEEECCCCCCCCEEEEEEEECCCCCCEEEECCCCCCCCCCCC
KDATLPSMEEVLPECYQQLVQIRGILEKHYRDMQDIEFTIEKGKLFMLQTRNGKRTAKAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEECCEEEEEEECCCCHHHHHH
IKVAVDMVKEGLIDEKTAVLRVSPSQLDQLLHPSLDPKAPRTIIAKGLPASPGAASGEVV
HHHHHHHHHHCCCCCCCEEEEECHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCEE
FTADEAEAAGRLGLKVILVRIETSPEDIHGMHAAQGILTARGGMTSHAAVVARGMGKCCV
EEECCHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHEECCCCCHHHHHHHHCCCCCEE
AGCGDIKVDYAAGQFVTAKGQVVKRGDTITLDGSTGEVMLGEVPTVAPQLTGDFGVLMGW
CCCCCEEEEECCCCEEECCCCEEECCCEEEECCCCCCEEECCCCCCCCCCCCCHHHHHHH
VDTYRKLKVRTNADTPNDSRVAREFGAEGIGLCRTEHMFFEADRIAAVREMILSEDVEGR
HHHHHEEEEEECCCCCCHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCHH
TKALAKILPMQKGDFLGIFREMKDLPVTIRLLDPPLHEFLPQEEKDVDALAKTMGVTAQT
HHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHCCHHHH
LKNKVDYLHEFNPMLGHRGCRLGLTFPEIYDMQVQAIMEAACELTKNEGFTIVPEIMIPL
HHHHHHHHHHCCHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHH
VGVVSELARLRENTVRVCEEVIARYGVKIDYLIGTMIELPRAALTADEIAREADFFSFGT
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
NDLTQTTFGLSRDDAGKFLPFYVESGLLEEDPFVSLDQNGVGILVKMAVEKGRTTRAGIK
CCHHHHHCCCCCCCCCCEEHHHHHCCCCCCCCCEEECCCCCEEEEEEEHHCCCCEECCEE
LGICGEHGGDPSSVIFCHKIGLDYVSCSPFRVPIARLAAAHAALGEGN
EEECCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AEKYVYFFGNGKAEGKADMKNLLGGKGANLAEMTAIGLPVPPGFTITTEVCTYYYANNK
CCEEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHEECCCCCCCCEEHHHHEEEEEECCC
SYPSVLAAQVAENLKSVEAIMGRTFGDPKNPLLVSVRSGARASMPGMMDTILNLGLNDET
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCHH
VQGIIVQSGDERFAYDAYRRFVQMYSDVVMGMDKEALEHLLEEKKAAKGVHLDTDLTAAD
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHH
WKELVGAFKAKIRETLGTAFPENPQEQLWGAVGAVFGSWMNQRAITYRRLNGIPADWGTA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VNVQSMVYGNMGNDCATGVAFTRDPSTGENYFYGEYLVNAQGEDVVAGIRTPQPINRANS
EEEHHHEECCCCCCHHCCCEEECCCCCCCCEEEEEEEECCCCCCEEEECCCCCCCCCCCC
KDATLPSMEEVLPECYQQLVQIRGILEKHYRDMQDIEFTIEKGKLFMLQTRNGKRTAKAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEECCEEEEEEECCCCHHHHHH
IKVAVDMVKEGLIDEKTAVLRVSPSQLDQLLHPSLDPKAPRTIIAKGLPASPGAASGEVV
HHHHHHHHHHCCCCCCCEEEEECHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCEE
FTADEAEAAGRLGLKVILVRIETSPEDIHGMHAAQGILTARGGMTSHAAVVARGMGKCCV
EEECCHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHEECCCCCHHHHHHHHCCCCCEE
AGCGDIKVDYAAGQFVTAKGQVVKRGDTITLDGSTGEVMLGEVPTVAPQLTGDFGVLMGW
CCCCCEEEEECCCCEEECCCCEEECCCEEEECCCCCCEEECCCCCCCCCCCCCHHHHHHH
VDTYRKLKVRTNADTPNDSRVAREFGAEGIGLCRTEHMFFEADRIAAVREMILSEDVEGR
HHHHHEEEEEECCCCCCHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCHH
TKALAKILPMQKGDFLGIFREMKDLPVTIRLLDPPLHEFLPQEEKDVDALAKTMGVTAQT
HHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHCCHHHH
LKNKVDYLHEFNPMLGHRGCRLGLTFPEIYDMQVQAIMEAACELTKNEGFTIVPEIMIPL
HHHHHHHHHHCCHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHH
VGVVSELARLRENTVRVCEEVIARYGVKIDYLIGTMIELPRAALTADEIAREADFFSFGT
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
NDLTQTTFGLSRDDAGKFLPFYVESGLLEEDPFVSLDQNGVGILVKMAVEKGRTTRAGIK
CCHHHHHCCCCCCCCCCEEHHHHHCCCCCCCCCEEECCCCCEEEEEEEHHCCCCEECCEE
LGICGEHGGDPSSVIFCHKIGLDYVSCSPFRVPIARLAAAHAALGEGN
EEECCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9168612 [H]