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The map label for this gene is atoS [H]

Identifier: 78224119

GI number: 78224119

Start: 3310424

End: 3312049

Strand: Direct

Name: atoS [H]

Synonym: Gmet_2923

Alternate gene names: 78224119

Gene position: 3310424-3312049 (Clockwise)

Preceding gene: 78224112

Following gene: 78224121

Centisome position: 82.81

GC content: 58.55

Gene sequence:

>1626_bases
TTGCGCCTGTCGCTCATTGCCAAACTCTCCCTCGCCATAAGCCTCATCCTCCTCGCCACCATGGGGCTCTTTGCCTACAT
TAACGTAGAACAACTCGAAAAGCTCCTCTACGAGGAGGCGGTCATCGATGCCGACAAGCTGAGCGAGACCATCATCCGCA
CCACCCACTACCACATGCTCGAAAACAACCTGAAACGGGCCTACCAGATCATCGACGAGGTAGGGTCCCAGCGGGGAATC
ATTGACCGCATCAGGATGGTCAACAAATTTGGCCTCGTAACCCACTCCACGGACTCAAAGGAGAAAGGCCTCTATCTGGA
CAAGAAGGCCGAGGCGTGCAGCATGTGCCACTCGGGGCCATCTCCCCTTGTCCACGCTACCACCATGAATCGCAGCCGTC
TCTTCACCAACAGGGAGGGGAAAGAGGTCCTGGGCCTCGCCAAGGCAATCTATAACGAGGAGCGTTGCTACACGGCCCCC
TGTCATTTTCACCCCAAGGAGGCCAAGGTCCTCGGCGTCCTGGACGTTATCGTTTCCCTCGACCAGATGCACCAGAAGGT
ATACGCCTATCGCAACGAGATCATCGTTCTCACGGTCCTGCAGATCGGCCTTATCGCCCTCTGTCTCACCTTCCTCACCC
AGCGCCTGGTCAACCGGCCGGTCCGGGCGCTGGTCAACCATGCCCATTTGATAGGCGGCGGCGACCTCGACGCCACGGTG
AGGGTCAAGAACCGCGACGAGCTCGGCGAACTGGCCGATGCCTTCAACGGCATGACAATAAACCTGAAAAAGGCACGGGT
AGAGTTGGAGGATTGGGGCAAAAACCTTGAAGACAAGGTGGAAGAGCGGACCCAGGAGATCAAGAAAATCCAGTCGCAGT
TGGTCCACTCCGAGAAGCTCGCCTCCCTGGGAGAACTTGTGGCAGGGATTGCCCACGAGATCAACAACCCCCTGACCGGC
ATCCTCGTCTTCGCGTCGCTGCTTGCCAGCGATTCGAAGCTCGATCCGTCCCTGAAGGGGGACCTGGACCTGATCGTCAA
GGAAACCCAGCGCTGCGCCCGAATCGTGAAGGGGCTGCTCGATTTCTCCAGGGAATCGATGCCCCAGAAAAAGCCCTCGT
CCCTGAACGCCATCATGGACGCAACACTGACGCTGGTCTGCAACCAGTCGAGCTTCCACGATATCAACGTCATCAAGGAG
TACAACCCCGACATCCCCGAGATGAACCTCGACCCGAACCAGATCGAGCAGGTGTTTATCAACCTGCTCCTGAACGCCTG
CCACGCCATCGGGGGTCCTGGGGAGATCAGGATCAGAACCGGCTTCGACCAGGAGCGGGAAGAGGCCTACGCCGCCATTA
CCGACAACGGCTGCGGGATTCCCGAGGAACATTTATCCAAAATATTCGACCCCTTCTTTTCCACCAAGGAAAACAAGGGT
ACCGGCCTGGGACTTTCGGTTTCCTACGGAATTATCGAGGGCCACGGTGGGAGAATCGAGGTCCGGAGCACCATGGGAGC
GGGGACCACCTTCACCTGCTGGCTGCCGCTCAACCATGACAGGGCAACGGCTACGGCCGAAGCGGCGGCGGCCAATCAGG
CGGCTCCCTTGCCGGAATCCTCCTGA

Upstream 100 bases:

>100_bases
GCCTGGAGCTTGACTAATATTGCAGCAAAGATTAAGCTGTATTTAAATTTACTACACCCCATCGATCCTTGCCACAACAG
TACCACCCGAGGTCATGCCC

Downstream 100 bases:

>100_bases
CTCTCCATCCGCTTTCATCGGCATAAGAAAAGGGGTCCACGGATTGTGGCCCCCTTTTTCGTTTCAATCGCCCCGCAGCA
GCGGCTTCGCGTCAATTGTT

Product: signal transduction histidine kinase, nitrogen specific, NtrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MRLSLIAKLSLAISLILLATMGLFAYINVEQLEKLLYEEAVIDADKLSETIIRTTHYHMLENNLKRAYQIIDEVGSQRGI
IDRIRMVNKFGLVTHSTDSKEKGLYLDKKAEACSMCHSGPSPLVHATTMNRSRLFTNREGKEVLGLAKAIYNEERCYTAP
CHFHPKEAKVLGVLDVIVSLDQMHQKVYAYRNEIIVLTVLQIGLIALCLTFLTQRLVNRPVRALVNHAHLIGGGDLDATV
RVKNRDELGELADAFNGMTINLKKARVELEDWGKNLEDKVEERTQEIKKIQSQLVHSEKLASLGELVAGIAHEINNPLTG
ILVFASLLASDSKLDPSLKGDLDLIVKETQRCARIVKGLLDFSRESMPQKKPSSLNAIMDATLTLVCNQSSFHDINVIKE
YNPDIPEMNLDPNQIEQVFINLLLNACHAIGGPGEIRIRTGFDQEREEAYAAITDNGCGIPEEHLSKIFDPFFSTKENKG
TGLGLSVSYGIIEGHGGRIEVRSTMGAGTTFTCWLPLNHDRATATAEAAAANQAAPLPESS

Sequences:

>Translated_541_residues
MRLSLIAKLSLAISLILLATMGLFAYINVEQLEKLLYEEAVIDADKLSETIIRTTHYHMLENNLKRAYQIIDEVGSQRGI
IDRIRMVNKFGLVTHSTDSKEKGLYLDKKAEACSMCHSGPSPLVHATTMNRSRLFTNREGKEVLGLAKAIYNEERCYTAP
CHFHPKEAKVLGVLDVIVSLDQMHQKVYAYRNEIIVLTVLQIGLIALCLTFLTQRLVNRPVRALVNHAHLIGGGDLDATV
RVKNRDELGELADAFNGMTINLKKARVELEDWGKNLEDKVEERTQEIKKIQSQLVHSEKLASLGELVAGIAHEINNPLTG
ILVFASLLASDSKLDPSLKGDLDLIVKETQRCARIVKGLLDFSRESMPQKKPSSLNAIMDATLTLVCNQSSFHDINVIKE
YNPDIPEMNLDPNQIEQVFINLLLNACHAIGGPGEIRIRTGFDQEREEAYAAITDNGCGIPEEHLSKIFDPFFSTKENKG
TGLGLSVSYGIIEGHGGRIEVRSTMGAGTTFTCWLPLNHDRATATAEAAAANQAAPLPESS
>Mature_541_residues
MRLSLIAKLSLAISLILLATMGLFAYINVEQLEKLLYEEAVIDADKLSETIIRTTHYHMLENNLKRAYQIIDEVGSQRGI
IDRIRMVNKFGLVTHSTDSKEKGLYLDKKAEACSMCHSGPSPLVHATTMNRSRLFTNREGKEVLGLAKAIYNEERCYTAP
CHFHPKEAKVLGVLDVIVSLDQMHQKVYAYRNEIIVLTVLQIGLIALCLTFLTQRLVNRPVRALVNHAHLIGGGDLDATV
RVKNRDELGELADAFNGMTINLKKARVELEDWGKNLEDKVEERTQEIKKIQSQLVHSEKLASLGELVAGIAHEINNPLTG
ILVFASLLASDSKLDPSLKGDLDLIVKETQRCARIVKGLLDFSRESMPQKKPSSLNAIMDATLTLVCNQSSFHDINVIKE
YNPDIPEMNLDPNQIEQVFINLLLNACHAIGGPGEIRIRTGFDQEREEAYAAITDNGCGIPEEHLSKIFDPFFSTKENKG
TGLGLSVSYGIIEGHGGRIEVRSTMGAGTTFTCWLPLNHDRATATAEAAAANQAAPLPESS

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=231, Percent_Identity=41.1255411255411, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=37.0689655172414, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1790300, Length=237, Percent_Identity=36.2869198312236, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87081816, Length=342, Percent_Identity=28.3625730994152, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI1789149, Length=437, Percent_Identity=24.9427917620137, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1789808, Length=356, Percent_Identity=25.2808988764045, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI145693157, Length=262, Percent_Identity=29.3893129770992, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI48994928, Length=246, Percent_Identity=27.2357723577236, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790346, Length=229, Percent_Identity=26.2008733624454, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788713, Length=258, Percent_Identity=25.5813953488372, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786783, Length=343, Percent_Identity=23.9067055393586, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=28.5106382978723, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786600, Length=221, Percent_Identity=23.9819004524887, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59831; Mature: 59831

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSLIAKLSLAISLILLATMGLFAYINVEQLEKLLYEEAVIDADKLSETIIRTTHYHML
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ENNLKRAYQIIDEVGSQRGIIDRIRMVNKFGLVTHSTDSKEKGLYLDKKAEACSMCHSGP
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEECCCCCCCCCCEECCHHHHHHHHCCCC
SPLVHATTMNRSRLFTNREGKEVLGLAKAIYNEERCYTAPCHFHPKEAKVLGVLDVIVSL
CCEEEEEECCCHHHCCCCCCHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHH
DQMHQKVYAYRNEIIVLTVLQIGLIALCLTFLTQRLVNRPVRALVNHAHLIGGGDLDATV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEE
RVKNRDELGELADAFNGMTINLKKARVELEDWGKNLEDKVEERTQEIKKIQSQLVHSEKL
EECCHHHHHHHHHHHCCCEEEEHHHEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ASLGELVAGIAHEINNPLTGILVFASLLASDSKLDPSLKGDLDLIVKETQRCARIVKGLL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DFSRESMPQKKPSSLNAIMDATLTLVCNQSSFHDINVIKEYNPDIPEMNLDPNQIEQVFI
HHHHHHCCCCCCCHHHHHHHHHHEEEECCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHH
NLLLNACHAIGGPGEIRIRTGFDQEREEAYAAITDNGCGIPEEHLSKIFDPFFSTKENKG
HHHHHHHHHCCCCCEEEEECCCCHHHHHHEEEEECCCCCCCHHHHHHHHHHHHCCCCCCC
TGLGLSVSYGIIEGHGGRIEVRSTMGAGTTFTCWLPLNHDRATATAEAAAANQAAPLPES
CCCEEEEEEEEEECCCCEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCC
S
C
>Mature Secondary Structure
MRLSLIAKLSLAISLILLATMGLFAYINVEQLEKLLYEEAVIDADKLSETIIRTTHYHML
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ENNLKRAYQIIDEVGSQRGIIDRIRMVNKFGLVTHSTDSKEKGLYLDKKAEACSMCHSGP
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEECCCCCCCCCCEECCHHHHHHHHCCCC
SPLVHATTMNRSRLFTNREGKEVLGLAKAIYNEERCYTAPCHFHPKEAKVLGVLDVIVSL
CCEEEEEECCCHHHCCCCCCHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHH
DQMHQKVYAYRNEIIVLTVLQIGLIALCLTFLTQRLVNRPVRALVNHAHLIGGGDLDATV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEE
RVKNRDELGELADAFNGMTINLKKARVELEDWGKNLEDKVEERTQEIKKIQSQLVHSEKL
EECCHHHHHHHHHHHCCCEEEEHHHEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ASLGELVAGIAHEINNPLTGILVFASLLASDSKLDPSLKGDLDLIVKETQRCARIVKGLL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DFSRESMPQKKPSSLNAIMDATLTLVCNQSSFHDINVIKEYNPDIPEMNLDPNQIEQVFI
HHHHHHCCCCCCCHHHHHHHHHHEEEECCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHH
NLLLNACHAIGGPGEIRIRTGFDQEREEAYAAITDNGCGIPEEHLSKIFDPFFSTKENKG
HHHHHHHHHCCCCCEEEEECCCCHHHHHHEEEEECCCCCCCHHHHHHHHHHHHCCCCCCC
TGLGLSVSYGIIEGHGGRIEVRSTMGAGTTFTCWLPLNHDRATATAEAAAANQAAPLPES
CCCEEEEEEEEEECCCCEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]