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The map label for this gene is nadB [C]

Identifier: 78224107

GI number: 78224107

Start: 3297065

End: 3298660

Strand: Reverse

Name: nadB [C]

Synonym: Gmet_2911

Alternate gene names: 78224107

Gene position: 3298660-3297065 (Counterclockwise)

Preceding gene: 78224108

Following gene: 78224104

Centisome position: 82.52

GC content: 63.16

Gene sequence:

>1596_bases
ATGTATCCGGATTCATTGTGCGATTCCATAGCCATTGTCGACGCCACCCGGGAAAAGCGGAAAGGGGAGGAGCTGCTAAG
GCTCACCAGTGCGGAGATGGAAGGGCTCCTCAGGCGGTACCACCCGGACTACCGGGAGGCGGGATTCCGGAACCTGAGGA
TCGGCGCCAACCGGGGCGACCGCACGACCCATGAGATCGCTGACCTTCTGGAGGCATTCAGCAACCTGGACCACTCGAAG
ATCAGCCTCGAACCCGAATTCGACACCGATGTGCTGGTTCTCGGCGGGGGAGGAGCGGGGGTGACGGCGGCTCTTTTCGC
CGAGAGCATGGGGGCGCGGGTCATCCTGGCCACGAAGCTGCGGGTCGGTAACTCCAATACCATCATGGCCCTTGGCGGGA
TGCAGGCGTCGGTCCACGAAGACGATTCACCCGTCAGACATTTTGCCGACACCATGGGGGCGGGGAAATTCGCCGGGAAG
AGGGAGCTGGTGAAGACCATGGTGGAGGACGGGCCGGCCATCGTCAAGTGGCTCCTGGAACTCGGCGTCGATTTCGACCG
GGACGAAGAGGGGAACCTCGCCACCCGCAAGGCGGGGGGGATCACTGCCCCGCGGATCATCTCCATCGGCGACTATACCG
GACTGAACATCATGAAGGTGCTGAAGGACGAGATCCGGAAAGGTGAGGGTATCGAAGTCATGGAATTCGCCCCGGCGGTG
GAGCTTACCACCAACGGGTTCGGCGAGTGCAACGGCGCCGTGCTCTTCGACCTGGGGAGGAAGCGGCATTTCACGGTGCG
GGCGCGGGCGGTGGTCCTGGCGACCGGCGGTTCGGGGCGGCTCCACTTCCAGGGGTTCCCCTCCTCCAACAACTTCGGCG
CCACCGGGGACGCCATCGTCCTCGCCTACCGTGCCGGGGCCAGGCTGGAGGGGATCGACTCGTTCCAGTATCATCCGACC
GGTGTCATGTTCCCTGACCACATGGTGGGAGTCCTGGTGACCGAGGCGGCCCGGAGTCTTGGCGGCCAGTTGGTGAATGG
GAAGGGGGAGCGGTTCATCAACGAGCTGGAGACCCGCGATGCCTGCTCAGCCGCCATCATCCGGGAATGTGAGGAGGGAA
ACGGCGTCAGGACCCCAGCCGGCAAGGTGGGAGTCTGGCTCGACACCCCTCTCATCGAAGAGACCCAGGGAAAGGGATTC
CTCAAGAGGCGCTTCCCCTCCATGTACCGGCATTTTATGCGGGTGAAGATCGACATCTCCAAGCGGCCTCTCCTCACCTA
TCCCACCCTCCACTACCAGAACGGCGGGATTCTCATCGACGAAAAGGGGGAGACCACGGTGAGAAATCTCTTCACGGCGG
GGGAGGCCGCAGGGGGAATCCATGGCCGGAATCGCGCCATGGGGAATTCGCTCCTGGACATCTTCGTCTTCGGCCGAAGG
GCGGGGCTGGCGGCGGCAAAACGCAAGTACAGCGAGCCGGGGAACGTCACCCTCGGTCATGTCTATCGCTACTACGACCG
GCTCAAGTCGCTGCGGATATCGAGCGTTGCCACGTCGCCGACCCTCTTTCCCGAGTTCATCGTGAGCAAGCTGTAG

Upstream 100 bases:

>100_bases
CAGATGGAATCGTTTGTCTTCGAGGCGGAATGGAGTCGGATCGTCGCCATGGGGGATGATGAGCTGAAGGCCTACTGCGC
GGCCATGGAGGGCCCCTAGC

Downstream 100 bases:

>100_bases
TTTCTGTTCCTGAACAATCAGAAATAGGTTACTTGCAGCAGCGGCGCCAGGATTCCCCGGTTTGAGATGGGATCGGAAAT
CTCGATGAGGCCGGGGGTGA

Product: fumarate reductase/succinate dehydrogenase flavoprotein-like

Products: fumarate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MYPDSLCDSIAIVDATREKRKGEELLRLTSAEMEGLLRRYHPDYREAGFRNLRIGANRGDRTTHEIADLLEAFSNLDHSK
ISLEPEFDTDVLVLGGGGAGVTAALFAESMGARVILATKLRVGNSNTIMALGGMQASVHEDDSPVRHFADTMGAGKFAGK
RELVKTMVEDGPAIVKWLLELGVDFDRDEEGNLATRKAGGITAPRIISIGDYTGLNIMKVLKDEIRKGEGIEVMEFAPAV
ELTTNGFGECNGAVLFDLGRKRHFTVRARAVVLATGGSGRLHFQGFPSSNNFGATGDAIVLAYRAGARLEGIDSFQYHPT
GVMFPDHMVGVLVTEAARSLGGQLVNGKGERFINELETRDACSAAIIRECEEGNGVRTPAGKVGVWLDTPLIEETQGKGF
LKRRFPSMYRHFMRVKIDISKRPLLTYPTLHYQNGGILIDEKGETTVRNLFTAGEAAGGIHGRNRAMGNSLLDIFVFGRR
AGLAAAKRKYSEPGNVTLGHVYRYYDRLKSLRISSVATSPTLFPEFIVSKL

Sequences:

>Translated_531_residues
MYPDSLCDSIAIVDATREKRKGEELLRLTSAEMEGLLRRYHPDYREAGFRNLRIGANRGDRTTHEIADLLEAFSNLDHSK
ISLEPEFDTDVLVLGGGGAGVTAALFAESMGARVILATKLRVGNSNTIMALGGMQASVHEDDSPVRHFADTMGAGKFAGK
RELVKTMVEDGPAIVKWLLELGVDFDRDEEGNLATRKAGGITAPRIISIGDYTGLNIMKVLKDEIRKGEGIEVMEFAPAV
ELTTNGFGECNGAVLFDLGRKRHFTVRARAVVLATGGSGRLHFQGFPSSNNFGATGDAIVLAYRAGARLEGIDSFQYHPT
GVMFPDHMVGVLVTEAARSLGGQLVNGKGERFINELETRDACSAAIIRECEEGNGVRTPAGKVGVWLDTPLIEETQGKGF
LKRRFPSMYRHFMRVKIDISKRPLLTYPTLHYQNGGILIDEKGETTVRNLFTAGEAAGGIHGRNRAMGNSLLDIFVFGRR
AGLAAAKRKYSEPGNVTLGHVYRYYDRLKSLRISSVATSPTLFPEFIVSKL
>Mature_531_residues
MYPDSLCDSIAIVDATREKRKGEELLRLTSAEMEGLLRRYHPDYREAGFRNLRIGANRGDRTTHEIADLLEAFSNLDHSK
ISLEPEFDTDVLVLGGGGAGVTAALFAESMGARVILATKLRVGNSNTIMALGGMQASVHEDDSPVRHFADTMGAGKFAGK
RELVKTMVEDGPAIVKWLLELGVDFDRDEEGNLATRKAGGITAPRIISIGDYTGLNIMKVLKDEIRKGEGIEVMEFAPAV
ELTTNGFGECNGAVLFDLGRKRHFTVRARAVVLATGGSGRLHFQGFPSSNNFGATGDAIVLAYRAGARLEGIDSFQYHPT
GVMFPDHMVGVLVTEAARSLGGQLVNGKGERFINELETRDACSAAIIRECEEGNGVRTPAGKVGVWLDTPLIEETQGKGF
LKRRFPSMYRHFMRVKIDISKRPLLTYPTLHYQNGGILIDEKGETTVRNLFTAGEAAGGIHGRNRAMGNSLLDIFVFGRR
AGLAAAKRKYSEPGNVTLGHVYRYYDRLKSLRISSVATSPTLFPEFIVSKL

Specific function: Catalyzes The Oxidation Of L-Aspartate To Iminoaspartate. [C]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=489, Percent_Identity=30.0613496932515, Blast_Score=171, Evalue=2e-42,
Organism=Escherichia coli, GI1788928, Length=422, Percent_Identity=31.7535545023697, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1790597, Length=396, Percent_Identity=31.5656565656566, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1786942, Length=432, Percent_Identity=34.2592592592593, Blast_Score=157, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17505833, Length=402, Percent_Identity=30.8457711442786, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17550100, Length=402, Percent_Identity=29.6019900497512, Blast_Score=148, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI71986328, Length=291, Percent_Identity=27.8350515463918, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322701, Length=425, Percent_Identity=31.0588235294118, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6322416, Length=425, Percent_Identity=31.2941176470588, Blast_Score=146, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6322511, Length=472, Percent_Identity=25.2118644067797, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320788, Length=487, Percent_Identity=27.3100616016427, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17137288, Length=434, Percent_Identity=31.5668202764977, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24655642, Length=434, Percent_Identity=31.5668202764977, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24655647, Length=434, Percent_Identity=31.5668202764977, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24663005, Length=457, Percent_Identity=28.6652078774617, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR015939
- InterPro:   IPR004112 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: 1.3.99.1

Molecular weight: Translated: 57957; Mature: 57957

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPDSLCDSIAIVDATREKRKGEELLRLTSAEMEGLLRRYHPDYREAGFRNLRIGANRGD
CCCHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEECCCCC
RTTHEIADLLEAFSNLDHSKISLEPEFDTDVLVLGGGGAGVTAALFAESMGARVILATKL
CHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEEEE
RVGNSNTIMALGGMQASVHEDDSPVRHFADTMGAGKFAGKRELVKTMVEDGPAIVKWLLE
EECCCCEEEEECCCEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
LGVDFDRDEEGNLATRKAGGITAPRIISIGDYTGLNIMKVLKDEIRKGEGIEVMEFAPAV
HCCCCCCCCCCCEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCE
ELTTNGFGECNGAVLFDLGRKRHFTVRARAVVLATGGSGRLHFQGFPSSNNFGATGDAIV
EEECCCCCCCCCEEEEECCCCEEEEEEEEEEEEEECCCCEEEEEECCCCCCCCCCCCEEE
LAYRAGARLEGIDSFQYHPTGVMFPDHMVGVLVTEAARSLGGQLVNGKGERFINELETRD
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHH
ACSAAIIRECEEGNGVRTPAGKVGVWLDTPLIEETQGKGFLKRRFPSMYRHFMRVKIDIS
HHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEEC
KRPLLTYPTLHYQNGGILIDEKGETTVRNLFTAGEAAGGIHGRNRAMGNSLLDIFVFGRR
CCCEEECCEEEECCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHEEHHHHCCC
AGLAAAKRKYSEPGNVTLGHVYRYYDRLKSLRISSVATSPTLFPEFIVSKL
CCHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHCC
>Mature Secondary Structure
MYPDSLCDSIAIVDATREKRKGEELLRLTSAEMEGLLRRYHPDYREAGFRNLRIGANRGD
CCCHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEECCCCC
RTTHEIADLLEAFSNLDHSKISLEPEFDTDVLVLGGGGAGVTAALFAESMGARVILATKL
CHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEEEE
RVGNSNTIMALGGMQASVHEDDSPVRHFADTMGAGKFAGKRELVKTMVEDGPAIVKWLLE
EECCCCEEEEECCCEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
LGVDFDRDEEGNLATRKAGGITAPRIISIGDYTGLNIMKVLKDEIRKGEGIEVMEFAPAV
HCCCCCCCCCCCEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCE
ELTTNGFGECNGAVLFDLGRKRHFTVRARAVVLATGGSGRLHFQGFPSSNNFGATGDAIV
EEECCCCCCCCCEEEEECCCCEEEEEEEEEEEEEECCCCEEEEEECCCCCCCCCCCCEEE
LAYRAGARLEGIDSFQYHPTGVMFPDHMVGVLVTEAARSLGGQLVNGKGERFINELETRD
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHH
ACSAAIIRECEEGNGVRTPAGKVGVWLDTPLIEETQGKGFLKRRFPSMYRHFMRVKIDIS
HHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEEC
KRPLLTYPTLHYQNGGILIDEKGETTVRNLFTAGEAAGGIHGRNRAMGNSLLDIFVFGRR
CCCEEECCEEEECCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHEEHHHHCCC
AGLAAAKRKYSEPGNVTLGHVYRYYDRLKSLRISSVATSPTLFPEFIVSKL
CCHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]